Koşuyolu Heart Journal最新文献_第2页

Chicken-egg and Cardiomyopathy Ventricular Extrasystole Paradox 鸡蛋与心肌病室性期外收缩悖论

Koşuyolu Heart Journal Pub Date : 2024-04-01 DOI: 10.51645/khj.2024.366

Meltem Altınsoy, U. Küçük

{"title":"Chicken-egg and Cardiomyopathy Ventricular Extrasystole Paradox","authors":"Meltem Altınsoy, U. Küçük","doi":"10.51645/khj.2024.366","DOIUrl":"https://doi.org/10.51645/khj.2024.366","url":null,"abstract":"Objectives: Left ventricular ejection fraction (LVEF) may decrease due to frequent ventricular extrasystoles (VESs). This study aimed to investigate whether the site of VES origin and other VES characteristics are associated with a decline in LVEF.\u0000 Methods: The rhythm Holter records and follow-up files of 400 patients who presented to the outpatient clinic with complaints such as palpitations, presyncope, syncope, and dyspnea between January 2017 and March 2023 and who were prescribed a rhythm Holter as part of their evaluation were retrospectively reviewed. The relationship between reduced LVEF, defined as LVEF <50% on echocardiography, and VES characteristics was examined in patients with normal LVEF and a VES burden above 10%, utilizing 24- and 48-h electrophysiology studies.\u0000 Results: The study comprised 34 patients with a mean age of 59.8±17.0 (range: 21–87) years. Among them, 55.9% (19 patients) were female, and the mean ejection fraction (EF) % was 49.5±11.3 (range: 25–67). Patients with EF % <50 (n=18) exhibited significantly higher diastolic diameter (5.3±0.5 vs. 4.7±0.5 cm, respectively; p=0.004), VES burden (32.3 vs. 16.7, respectively; p=0.0001), longer coupling interval (CI) measurements (p=0.018), and QRS duration (p=0.0001) compared to patients with EF % >50 (n=16). A positive correlation was observed between VES load and QRS duration in the group with EF <50% (r=0.664; p=0.002). In patients who developed VES-induced cardiomyopathy (CMP), VES originated from the mitral annulus (p<0.001), whereas VES originating from the right ventricular outflow tract was significantly associated with the non-CMP group (p<0.001).\u0000 Conclusion: The burden of VESs may be associated with CMP, as well as longer QRS duration, CI, and exit location.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"173 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140779964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prognostic Value of Logistic Clinical Syntax Score in Coronary Bifurcation Lesions Treated with Double Stent Technique Logistic临床句法评分对双支架治疗冠状动脉分叉病变的预后价值

Koşuyolu Heart Journal Pub Date : 2022-12-01 DOI: 10.51645/khj.2022.m269

Gokhan Demirci, S. Aslan, A. R. Demir, B. Uygur, Ayan Işık, Enes Arslan, M. Ertürk

{"title":"Prognostic Value of Logistic Clinical Syntax Score in Coronary Bifurcation Lesions Treated with Double Stent Technique","authors":"Gokhan Demirci, S. Aslan, A. R. Demir, B. Uygur, Ayan Işık, Enes Arslan, M. Ertürk","doi":"10.51645/khj.2022.m269","DOIUrl":"https://doi.org/10.51645/khj.2022.m269","url":null,"abstract":"Introduction: In this study, we aimed to investigate the relationship between the preprocedural logistic clinical SYNTAX score (Log CSS) and major cardiovascular events (MACE) in patients with true bifurcation lesions who underwent revascularization with the double stent strategy.\u0000 Patients and Methods: A total of 233 non-ST elevation myocardial infarction (NSTEMI) patients who underwent revascularization with a double stent strategy were retrospectively included in the study. Anatomical SYNTAX score (SS) and log CSS were calculated. The patients were divided into two groups according to the cut-off value determined by ROC analysis. The prediction of two-year MACE with Log CSS was evaluated.\u0000 Results: MACE developed in 33.9% of patients with high Log CSS and 8.5% of patients with low Log CSS (p< 0.001). In the Kaplan-Meier survival analysis, the long-term survival of the high Log CSS patients was significantly lower than the low Log CSS group (Log-rank p< 0.001). In multivariate COX analyses, high Log CCS (HR= 3.781; 95% CI= 1.706-8.377; p= 0.001) was the strongest independent predictor of MACE.\u0000 Conclusion: Log CSS can be a simple and useful tool to predict the development of MACE in patients with true bifurcation lesions revascularized by percutaneous coronary intervention.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"74 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121154225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sacubitril/Valsartan Treatment in Heart Failure Increases The Left Ventricular Ejection Fraction: A Bayesian Analysis 舒比利/缬沙坦治疗心力衰竭增加左心室射血分数:贝叶斯分析

Koşuyolu Heart Journal Pub Date : 2022-12-01 DOI: 10.51645/khj.2022.m261

Oğuzhan Birdal, M. Saygı, Pınar Demir Gündoğmuş, E. Aksakal, Flora Özkalaycı

{"title":"Sacubitril/Valsartan Treatment in Heart Failure Increases The Left Ventricular Ejection Fraction: A Bayesian Analysis","authors":"Oğuzhan Birdal, M. Saygı, Pınar Demir Gündoğmuş, E. Aksakal, Flora Özkalaycı","doi":"10.51645/khj.2022.m261","DOIUrl":"https://doi.org/10.51645/khj.2022.m261","url":null,"abstract":"Introduction: Heart failure is an important leading cause of mortality and morbidity despite optimal medical treatment and device therapy. Sacubitril/valsartan, a first-generation drug, was approved to use heart failure treatment recently. There are limited studies on the relationship between sacubitril/valsartan and left ventricular contraction. In our study, we aimed to evaluate the changes in left ventricular ejection fraction (LVEF) after sacubitril/valsartan treatment.\u0000 Patients and Methods: Fifty-two patients with heart failure and reduced ejection fraction (HFrEF) were enrolled in this study. The baseline demographic, clinical, and echocardiographic characteristics of 52 patients were compared using the Bayesian method.\u0000 Results: Fifty-two patients with heart failure and reduced ejection fraction (HFrEF) were included in the final analysis (66.2 ± 9.3 years, 69.2% male). Sacubitril/valsartan initial dose was low in 44.2% of patients, and intermediate in 55.8%. In the low initial dose population, the increase in absolute LVEF was 3.87 (95% HDI 1.53-6.20) and in the intermediate initial dose population, the increase in absolute LVEF was 5.89 (95% HDI 4.18-7.61). In the female population, the increase in absolute LVEF was 5.56 (95% HDI 3.49-7.63) and in the male population 4.75 (95% HDI 2.91-6.58) respectively.\u0000 Conclusion: In this study, we demonstrated that sacubitril/valsartan is associated with increased LVEF regardless of baseline clinical characteristics.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126412529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Predictive Value of C-Reactive ProteinAlbumin Ratio in Long-Term Mortality Among Patients Undergoing Carotid Artery Stenting c反应蛋白白蛋白比值对颈动脉支架植入术患者长期死亡率的预测价值

Koşuyolu Heart Journal Pub Date : 2022-12-01 DOI: 10.51645/khj.2022.m322

C. Toprak

{"title":"The Predictive Value of C-Reactive ProteinAlbumin Ratio in Long-Term Mortality Among Patients Undergoing Carotid Artery Stenting","authors":"C. Toprak","doi":"10.51645/khj.2022.m322","DOIUrl":"https://doi.org/10.51645/khj.2022.m322","url":null,"abstract":"Introduction: Several inflammatory biomarkers reported in previous research have been associated with the severity of carotid artery stenosis, symptomatic carotid lesions, and carotid stent restenosis. The C-reactive protein (CRP)-to-serum albumin ratio (CAR) has been shown to predict peripheral artery disease severity in patients with carotid artery disease (CAD). However, the relationship between CAR and long-term mortality in CAD patients following carotid artery stenting (CAS) remains uncertain. The goal of this study was to investigate the ability of CAR to predict long-term mortality in patients with CAS.\u0000 Patients and Methods: A total of 998 CAD patients who had percutaneous carotid artery intervention were reviewed retrospectively, and 482 of them without follow-up data were excluded from this study. The study included patients who had percutaneous carotid artery intervention between 2012 and 2018. Before the procedure, serum CRP, complete blood counts, and albumin levels were measured. The relationships between patients’ characteristics, procedural details, and CAR with all-cause mortality were evaluated in the long-term follow-up after CAS.\u0000 Results: Older age (HR= 1.044; 95% CI= 1.001-1.089; p= 0.046), smoking (HR= 2.636; 95% CI= 1.213- 5.728; p= 0.014), blood urea (HR= 1.017; 95% CI= 1.002-1.033; p= 0.025), albumin (HR= 0.252; 95% CI= 0.132-0.480; p< 0.001), CRP levels (HR= 1.336; 95% CI= 1.055-1.691; p= 0.016) and CAR (HR= 1.012; 95% CI= 1.003-1.022; p= 0.008) were statistically associated with all-cause mortality at 55.2 ± 12.4 months follow-up after CAS in multivariate COX regression analysis.\u0000 Conclusion: In patients undergoing CAS, CAR was independently related to long-term mortality. CAR could be used in this population for risk stratification to achieve closer follow-up and optimize treatment.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125118683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Impact of Obesity and Patient-Reported Reasons on Patient Noncompliance with Compression Stockings 肥胖和患者报告的原因对患者不遵守压缩袜的影响

Koşuyolu Heart Journal Pub Date : 2022-12-01 DOI: 10.51645/khj.2022.m321

Abdulkerim Özhan, M. Baştopçu, C. Kocaaslan, M. Bademci, Ahmet Öztekin, F. Bayraktar, Betul Nur Keser, Ebuzer Aydın

{"title":"The Impact of Obesity and Patient-Reported Reasons on Patient Noncompliance with Compression Stockings","authors":"Abdulkerim Özhan, M. Baştopçu, C. Kocaaslan, M. Bademci, Ahmet Öztekin, F. Bayraktar, Betul Nur Keser, Ebuzer Aydın","doi":"10.51645/khj.2022.m321","DOIUrl":"https://doi.org/10.51645/khj.2022.m321","url":null,"abstract":"Introduction: The aim of this study is to investigate the impact of obesity on patient compliance with elastic compression stockings and to reveal patient behavior-related and compression stockings-related factors for noncompliance.\u0000 Patients and Methods: Between July and August 2022, a total of 246 patients with chronic venous insufficiency were included in the study. The patients were divided into two groups, obese and non-obese patients (88 vs. 158 patients), and questioned for proper use of compression stockings and the patient-reported reasons for the non-compliance.\u0000 Results: The mean age was 49.0 ± 13.1, and the mean BMI was 28.6 ± 5.2. Only 51 patients (20.7%) out of 246 complied with stocking use. The mean number of days per week in which the compression stockings were properly used was 2.9 ± 1.7 in the study population. Patient compliance was higher in the non-obese group (12.5% vs. 25.3%, p= 0.017), and the number of days per week in which the compression stockings were worn properly was higher in the non-obese group (2.6 ± 1.3 vs. 3.1 ± 1.9, p= 0.032).\u0000 Conclusion: The compliance of our patients with elastic compression stockings was found to be as low as 20.7%. Compliance was lower in the group of obese patients. Obesity and diabetes mellitus were the only factors associated with noncompliance in univariate logistic regression analysis. Further studies are needed in larger patient populations to increase the rate of patient compliance.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134449867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Neutrophil/Lymphocyte Ratio Changes on Morbidity in the Perioperative Period of Neonates with Total Abnormal Pulmonary Venous Return Anomaly 中性粒细胞/淋巴细胞比值变化对新生儿全肺静脉回流异常围手术期发病率的影响

Koşuyolu Heart Journal Pub Date : 2022-12-01 DOI: 10.51645/khj.2022.m313

D. Öztürk, Behzat Tüzün

{"title":"The Effect of Neutrophil/Lymphocyte Ratio Changes on Morbidity in the Perioperative Period of Neonates with Total Abnormal Pulmonary Venous Return Anomaly","authors":"D. Öztürk, Behzat Tüzün","doi":"10.51645/khj.2022.m313","DOIUrl":"https://doi.org/10.51645/khj.2022.m313","url":null,"abstract":"Introduction: Total abnormal pulmonary venous return anomaly (TAPVD) is a congenital heart disease characterized by abnormal pulmonary venous drainage to the right atrium. The Neutrophil/Lymphocyte Ratio (NLR) is used to predict mortality and morbidity after congenital heart surgery. In this study, the effect of postoperative NLR changes on prolonged intensive care unit stay in newborns with TAPVD was searched.\u0000 Patients and Methods: The newborns with TAPVD who were followed up and operated on in the pediatric cardiac intensive care unit between May 1, 2020, and May 1, 2022, were included in the study. Hematological parameters and NLR changes were recorded before and after the operation (1st-2nd-3rd days). Long ICU duration (PCILOS, being in the longest 25 percent as duration) was accepted as morbidity. The effects of NLO changes on PCILOS were examined.\u0000 Results: Twenty-four patients were included in the study. The median age was 18 days (IQR 12 days-24 days) and the median weight was 3 kg (IQR= 2.8-3.2). Fifteen patients were male (63%). Median mechanical ventilator duration, intensive care unit stay, and hospital stay were 40 hours (IQR= 30-48 hours), seven days (IQR= 5-9), and 15 days (IQR= 12-18), respectively. PCILOS duration was determined as >9 days. Three patients (12.5%) died in the postoperative first 30 days. Preoperative NLR value> 1.9 and postoperative 3rd day NLR> 2.8 predicted PCILOS strongly.\u0000 Conclusion: High NLR values in the preoperative and early postoperative periods of neonates with total abnormal pulmonary venous return anomaly may be helpful to predict prolonged ICU stay.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"191 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127025792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Adaptation to Turkish of the Self-Care of Heart Failure Index: A Validity and Reliability Study 心衰自理指数对土耳其语的适应性:效度与信度研究

Koşuyolu Heart Journal Pub Date : 2022-12-01 DOI: 10.51645/khj.2022.m300

Fusun Afsar, S. Kayalı, Vildan Kesgin, T. Akgün, Habip Yılmaz

{"title":"Adaptation to Turkish of the Self-Care of Heart Failure Index: A Validity and Reliability Study","authors":"Fusun Afsar, S. Kayalı, Vildan Kesgin, T. Akgün, Habip Yılmaz","doi":"10.51645/khj.2022.m300","DOIUrl":"https://doi.org/10.51645/khj.2022.m300","url":null,"abstract":"Introduction: Heart failure is a chronic and progressive disease with increasing prevalence and incidence worldwide, despite advances in science and technology, and it necessitates long-term follow-up, treatment, and care. Self-care in heart failure is one of the fundamental elements of quality of life and disability-free living. The aim of this study was to assess the validity and reliability of the Turkish version of the Self-Care of Heart Failure Index v.2 (SCHFI).\u0000 Patients and Methods: The study sample included 233 patients who presented with a diagnosis of heart failure and volunteered to participate in the research at a training and research hospital. The data were collected using a personal information form and the SCHFI. The SCHFI was translated into Turkish, and the internal consistency coefficient and the item-total points reliability coefficient were analyzed for the reliability study. To determine structure validity, Explanatory Factor Analysis and Confirmatory Factor Analysis were performed.\u0000 Results: The adaptation of the SCHFI to Turkish culture was found to have high structure validity and internal consistency in the reliability and validity studies.\u0000 Conclusion: We concluded that the Self-Care of Heart Failure Index can be used as a unidimensional scale.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134374477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association Between Systemic ImmuneInflammation Index and Long-Term Mortality in Patients with Critical Limb-Threatening Ischemia Undergoing Endovascular Therapy Below the Knee 膝关节以下血管内治疗严重肢体缺血患者的全身免疫炎症指数与长期死亡率的关系

Koşuyolu Heart Journal Pub Date : 2022-12-01 DOI: 10.51645/khj.2022.m316

Y. Avcı, M. Duran, A. Demir, Gokhan Demirci, Ömer Taşbulak, A. Güler, A. Yalçın, Sezgin Atmaca, M. Ertürk

{"title":"Association Between Systemic ImmuneInflammation Index and Long-Term Mortality in Patients with Critical Limb-Threatening Ischemia Undergoing Endovascular Therapy Below the Knee","authors":"Y. Avcı, M. Duran, A. Demir, Gokhan Demirci, Ömer Taşbulak, A. Güler, A. Yalçın, Sezgin Atmaca, M. Ertürk","doi":"10.51645/khj.2022.m316","DOIUrl":"https://doi.org/10.51645/khj.2022.m316","url":null,"abstract":"Introduction: Endovascular interventions have been increasingly used for the treatment of patients suffering from below-the-knee (BTK) ischemic lesions. Yet, there is a paucity of data regarding long-term adverse events in patients with critical limb ischemia (CLI) undergoing endovascular revascularization for BTK lesions. Recently introduced systemic immune-inflammation index (SII) is a reliable indicator of poor outcomes in various cardiovascular conditions. Herein, we aimed to investigate the prognostic role of the SII on mortality in patients with CLI undergoing endovascular revascularization for BTK lesions.\u0000 Patients and Methods: The records of 112 patients with symptomatic CLI undergoing endovascular revascularization for BTK lesions between January 2015 and December 2019 were analyzed. Patients were divided into groups with low and high SII values based on an SII cut-off value derived from a ROC analysis. For each group, procedural details and follow-up outcomes were analyzed.\u0000 Results: The mean follow-up time was 40.3 ± 19.9 months. According to our data, patients with high SII values had higher rates of mortality compared to patients with low SII values (65.2% vs 30.3%, p< 0.001). To determine the SII cut-off value for predicting mortality, the ROC curve was drawn, and the best cut-off value was determined as 966 by using the Youden index, (AUC= 0.658, 95% CI= 0.556-0.760, p= 0.004). Cox multivariate regression analysis also identified the SII score as an independent predictor of mortality.\u0000 Conclusion: SII is an independent predictor of mortality, especially among patients with CLI who underwent endovascular revascularization for BTK lesions.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128161352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Should We Hesitate to Use Skeletonized Bilateral Internal Mammary Artery? 我们应该犹豫使用双侧乳腺内动脉骨架吗?

Koşuyolu Heart Journal Pub Date : 2022-12-01 DOI: 10.51645/khj.2022.m281

Ayça Özgen, Hamdi Toköz

引用次数: 0

Relationship Between Syntax Score and Cystatin C in Patients with Acute Coronary Syndrome 急性冠脉综合征患者句法评分与胱抑素C的关系

Koşuyolu Heart Journal Pub Date : 2022-12-01 DOI: 10.51645/khj.2022.m246

K. Toprak

{"title":"Relationship Between Syntax Score and Cystatin C in Patients with Acute Coronary Syndrome","authors":"K. Toprak","doi":"10.51645/khj.2022.m246","DOIUrl":"https://doi.org/10.51645/khj.2022.m246","url":null,"abstract":"Introduction: The SYNTAX (SYNergy between PCI with TAXUS and Cardiac Surgery) score (SS) is an angiographic scoring system to determine the severity of coronary artery disease (CAD). As far as we know, studies examining the relationship between SYNTAX Score and Cystatin C (Cys-C) are limited in the literature. In this study, we aimed to investigate the relationship between Cys-C level and SS in patients presenting with ST-elevation myocardial infarction (STEMI).\u0000 Patients and Methods: One hundred ninety-two patients who underwent coronary angiography for STEMI between June 2021 and December 2021 in our center were included in the study. The patients were divided into two groups according to their SS values: Group 1 included patients with SS<22, and Group 2 included patients with SS≥ 22. The two groups were compared in terms of baseline characteristics and serum Cys-C levels.\u0000 Results: Patients in Group 2 had significantly higher Cys-C levels than those in Group 1 (1.7 ± 0.53 vs 1.3 ± 0.29; p= 0.006). In the correlation analysis, SS showed a positive correlation with the Cys-C level (r= 0.189, p= 0.015). Multivariate logistic regression analysis showed that Cys-C level was an independent predictor of high SS (β=0.306, p= 0.006). When receiver operating characteristic (ROC) curve analysis was performed, the optimal cut-off value of Cys-C to predict severe coronary artery disease (indicating high SS) was Cys-C≥ 1.56, which was predictive for severe coronary artery disease with 74% sensitivity and 72% specificity [area under the curve (AUC)= 0.745, 95% confidence interval (CI)= 0.624-0.835, p<0.001).\u0000 Conclusion: Cystatin C levels are independently associated with high SS in STEMI patients. In summary, our findings show that Cys-C is a promising clinical biomarker that can be used to assess the severity of coronary artery lesions, potentially providing additional information to established risk markers.","PeriodicalId":239985,"journal":{"name":"Koşuyolu Heart Journal","volume":"150 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123392776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0