Women & Health最新文献_第9页

Regulatory mechanism of GPER in the invasion and migration of ectopic endometrial stromal cells in endometriosis. GPER 在子宫内膜异位症异位子宫内膜基质细胞侵袭和迁移中的调控机制。

IF 1.6 4区医学

Women & Health Pub Date : 2024-02-07 Epub Date: 2024-01-30 DOI: 10.1080/03630242.2023.2296522

Hongyan Shi, Kejun Xu, Mengna Huang, Meiya Mao, Jilan Ou

{"title":"Regulatory mechanism of GPER in the invasion and migration of ectopic endometrial stromal cells in endometriosis.","authors":"Hongyan Shi, Kejun Xu, Mengna Huang, Meiya Mao, Jilan Ou","doi":"10.1080/03630242.2023.2296522","DOIUrl":"10.1080/03630242.2023.2296522","url":null,"abstract":"Endometriosis (EMS) is a chronic inflammatory disorder of high incidence that causes serious reproductive consequences. High estrogen production is a consistently observed endocrine feature of EMS. The present study aims to probe the molecular mechanism of G protein-coupled estrogen receptor 1 (GPER) in the invasion and migration of ectopic endometrial stromal cells (Ect-ESCs) and provides a new rationale for EMS treatment. Eutopic and ectopic endometrial tissues were collected from 41 EMS patients, and primary ESCs were separated. GPER, miR-16-5p, and miR-103a-3p levels in cells and tissues were determined by qRT-PCR or Western blot assay. Cell viability, proliferation, invasion, and migration were evaluated by CCK-8, colony formation, and Transwell assays. The upstream miRNAs of GPER were predicted by databases, and dual-luciferase assay was performed to validate the binding of miR-16-5p and miR-103a-3p to GPER 3'UTR. GPER was highly expressed in EMS tissues and Ect-ESCs. Inhibition of GPER mitigated the proliferation, invasion, and migration of Ect-ESCs. GPER was regulated by miR-16-5p and miR-103a-3p. Overexpression of miR-16-5p and miR-103a-3p negatively regulated GPER expression and inhibited the invasion and migration of Ect-ESC. In conclusion, GPER promoted the invasion and migration of Ect-ESCs, which can be reversed by upstream miR-16-5p and miR-103a-3p.","PeriodicalId":23972,"journal":{"name":"Women & Health","volume":" ","pages":"109-120"},"PeriodicalIF":1.6,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139040485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spousal support and dyadic adjustment in the early postpartum period. 产后早期的配偶支持和夫妻适应。

IF 1.6 4区医学

Women & Health Pub Date : 2024-02-07 Epub Date: 2024-01-30 DOI: 10.1080/03630242.2024.2304891

Sureyya Kılıç, Ruveyde Can, Sema Dereli Yilmaz

引用次数: 0

SOS reproductive healthcare: a call for action. SOS 生殖保健：行动呼吁。

IF 1.6 4区医学

Women & Health Pub Date : 2024-02-07 Epub Date: 2024-01-30 DOI: 10.1080/03630242.2024.2308308

Márcia Mendonça Carneiro

引用次数: 0

Healthcare utilization before and during the COVID-19 pandemic among mothers and birthing parents with elevated levels of postpartum depression symptoms. 在 COVID-19 大流行之前和期间，产后抑郁症状加重的母亲和分娩父母的医疗保健使用情况。

IF 1.6 4区医学

Women & Health Pub Date : 2024-02-07 Epub Date: 2024-01-30 DOI: 10.1080/03630242.2024.2308516

Vanessa Luk, Haley Layton, Calan Savoy, Kathryn Huh, Ryan J Van Lieshout

{"title":"Healthcare utilization before and during the COVID-19 pandemic among mothers and birthing parents with elevated levels of postpartum depression symptoms.","authors":"Vanessa Luk, Haley Layton, Calan Savoy, Kathryn Huh, Ryan J Van Lieshout","doi":"10.1080/03630242.2024.2308516","DOIUrl":"10.1080/03630242.2024.2308516","url":null,"abstract":"Little is known about the healthcare utilization of mothers and birthing parents experiencing elevated levels of symptoms of postpartum depression (PPD), particularly during the COVID-19 pandemic. This study examined how healthcare utilization changed in these individuals during COVID-19. Individuals living in Ontario, Canada, with Edinburgh Postnatal Depression Scale Scores ≥ 10 were recruited into two separate randomized controlled trials of a 1-day intervention for PPD before (pre-COVID-19, n = 441) and during the pandemic (COVID-19, n = 287). Participants in both samples completed the same health resource use questionnaire, self-reporting the number of virtual and/or in-person visits to specific healthcare services over the three months preceding their treatment intervention. Use of medications, mental health care, primary care, hospital-based care, allied health care, and overall healthcare utilization were compared between the pre-COVID-19 and COVID-19 groups. While participants had higher levels of PPD symptoms during COVID-19, differences were not seen in the use of specific categories of care (e.g. mental health and primary care). However, before and after statistically adjusting for covariates, overall healthcare utilization decreased from an average of 9.5 visits prior to COVID-19 to 6.9 during COVID-19 (p < .001), a change that was at least partly contributed to by reductions in visits to allied health professionals (e.g. dentists and physiotherapists). Overall healthcare utilization decreased by 27 % in mothers and birthing parents seeking treatment for elevated levels of PPD symptoms during the COVID-19 pandemic in Ontario, Canada - despite higher levels of PPD symptoms - highlighting the need to support and address barriers to postpartum care.","PeriodicalId":23972,"journal":{"name":"Women & Health","volume":" ","pages":"175-184"},"PeriodicalIF":1.6,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139520641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Can't stop, won't stop - understanding anxiety's role in cyberchondria among pregnant women. 停不下来，停不下来--了解焦虑在孕妇网络成瘾中的作用。

IF 1.6 4区医学

Women & Health Pub Date : 2024-02-07 Epub Date: 2024-01-30 DOI: 10.1080/03630242.2024.2308525

Matea Šoštarić, Nataša Jokić-Begić, Matea Vukušić Mijačika

{"title":"Can't stop, won't stop - understanding anxiety's role in cyberchondria among pregnant women.","authors":"Matea Šoštarić, Nataša Jokić-Begić, Matea Vukušić Mijačika","doi":"10.1080/03630242.2024.2308525","DOIUrl":"10.1080/03630242.2024.2308525","url":null,"abstract":"Online health research is common during pregnancy, especially if women are facing complications. Given the unpleasant emotions women experience after research, it is surprising that cyberchondria, excessive and repeated online health research caused by anxiety that intensifies such anxiety, has not been studied in pregnant women. Therefore, the aim of this study was to examine the predictors of cyberchondria among women with and without pregnancy complications, accounting for health anxiety (a worry regarding personal health) and pregnancy-specific anxiety (concerns related to pregnancy and childbirth). A total of 360 pregnant women completed a questionnaire consisted of Short Health Anxiety Inventory, Pregnancy Concerns Scale and Short Cyberchondria Scale. The results of one-way MANOVA showed that women who had medically complicated pregnancy had higher levels of health anxiety, pregnancy-specific anxiety and cyberchondria compared to those without complications. A hierarchical multiple regression analysis showed that health anxiety and pregnancy-specific anxiety were predictors of cyberchondria but had different roles depending on complications. Pregnancy-specific anxiety predicted cyberchondria in both groups above health anxiety. Health anxiety predicted cyberchondria only in women without complications. In conclusion, women with complications have a higher chance of experiencing cyberchondria. Pregnancy-specific and health anxiety are risk factors for cyberchondria in pregnant women.","PeriodicalId":23972,"journal":{"name":"Women & Health","volume":" ","pages":"185-194"},"PeriodicalIF":1.6,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139520629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of Pilates exercise during pregnancy on delivery outcomes: a systematic review and meta-analysis. 孕期普拉提运动对分娩结果的影响：系统回顾和荟萃分析。

IF 1.6 4区医学

Women & Health Pub Date : 2024-02-07 Epub Date: 2024-01-30 DOI: 10.1080/03630242.2024.2304893

Saeed Baradwan, Khalid Khadawardi, Nada M Alayed, Khalid M Akkour, Maram Salaheldeen Mahmoud, Ahmed Mohamed Abdelhakim, Mohammad Sunoqrot, Ahmed Sherif Abdel Hamid

{"title":"The effect of Pilates exercise during pregnancy on delivery outcomes: a systematic review and meta-analysis.","authors":"Saeed Baradwan, Khalid Khadawardi, Nada M Alayed, Khalid M Akkour, Maram Salaheldeen Mahmoud, Ahmed Mohamed Abdelhakim, Mohammad Sunoqrot, Ahmed Sherif Abdel Hamid","doi":"10.1080/03630242.2024.2304893","DOIUrl":"10.1080/03630242.2024.2304893","url":null,"abstract":"A systematic review and meta-analysis were conducted to investigate the effectiveness of the Pilates exercise program during pregnancy on different delivery outcomes. Various databases were searched from inception until November 2022. The included studies compared Pilates exercise to routine antenatal care in pregnant women. The primary outcomes assessed were vaginal and cesarean delivery rates, as well as labor duration. Secondary outcomes included episiotomy incidence, Apgar scores, and epidural analgesia. Seven studies met the inclusion criteria, involving a total of 1,003 patients. Results indicated a significant increase in the vaginal delivery rate among the Pilates exercise group compared to the control group (p < .001). Moreover, the Pilates exercise group exhibited significantly reduced rates of cesarean delivery and shorter labor duration. Pilates exercise was associated with a significant decline in the incidence of episiotomy and the number of women requiring epidural analgesia during delivery (p < .001 & p = .008). In addition, Apgar scores at one and five minutes were significantly higher in the Pilates exercise group compared to the control group (p < .001). In conclusion, Pilates exercise during pregnancy has a positive effect on maternal outcomes and Apgar scores. However, more trials are needed to confirm these findings.","PeriodicalId":23972,"journal":{"name":"Women & Health","volume":" ","pages":"131-141"},"PeriodicalIF":1.6,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139467124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of physical activity on the relationship between adiposity and cardiac autonomic modulation in female breast cancer survivors: a longitudinal study. 体育锻炼对女性乳腺癌幸存者脂肪含量与心脏自律神经调节之间关系的影响：一项纵向研究。

IF 1.6 4区医学

Women & Health Pub Date : 2024-02-07 Epub Date: 2024-01-30 DOI: 10.1080/03630242.2024.2305342

Mariana R Palma, William R Tebar, Victor S Beretta, Luiz Carlos M Vanderlei, Cristina E P T Fregonesi, Fernanda E Ribeiro, Daniela T Caldeira, Ercy M C Ramos, Gabriel G Cucato, Gerson Ferrari, Raphael M Ritti-Dias, Diego G D Christofaro

{"title":"Effect of physical activity on the relationship between adiposity and cardiac autonomic modulation in female breast cancer survivors: a longitudinal study.","authors":"Mariana R Palma, William R Tebar, Victor S Beretta, Luiz Carlos M Vanderlei, Cristina E P T Fregonesi, Fernanda E Ribeiro, Daniela T Caldeira, Ercy M C Ramos, Gabriel G Cucato, Gerson Ferrari, Raphael M Ritti-Dias, Diego G D Christofaro","doi":"10.1080/03630242.2024.2305342","DOIUrl":"10.1080/03630242.2024.2305342","url":null,"abstract":"This longitudinal study aimed to analyze the influence of physical activity (PA) on the relationship between body adiposity and cardiac autonomic modulation (CAM) in women survivors of breast cancer. We collected body adiposity through electrical bioimpedance considering body fat percentage (BFP), CAM through heart rate variability (considering RMSSD, SDNN, PNN50, LF (m2), HF (m2), SD1 indexes and SD1/SD2 ratio) and PA through a questionnaire in 64 participants (58.0 ± 9.6 years), recruited through the local association of support for breast cancer and by direct indications from city mastologists. After insertion of PA into the multivariate statistical model, significant attenuation was observed in the relationship between body adiposity and CAM for the indices: SDNN (β = -0.94; 95 percent CI: -1.93; 0.04; p = .060) and SD1/SD2 (β = -0.01;95 percent CI = -0.02; 0.001; p = .065). In conclusion, it was observed that PA was able to mitigate the relationships between BFP and CAM (considering SDNN index and SD1/SD2 ratio) in breast cancer survivors.","PeriodicalId":23972,"journal":{"name":"Women & Health","volume":" ","pages":"165-174"},"PeriodicalIF":1.6,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139479386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Menstrual and psychosocial characteristics associated with high-risk of premenstrual dysphoric disorder among university students: a cross-sectional study. 与大学生经前期情感障碍高风险相关的月经和社会心理特征：一项横断面研究。

IF 1.6 4区医学

Women & Health Pub Date : 2024-02-07 Epub Date: 2024-01-30 DOI: 10.1080/03630242.2024.2304899

Jung Jae Lee, Tongyao Wang, Jeongok Park, Bohee Lee, Hyojin Lee, Polly Wai Chi Li, Edmond Pui Hang Choi

{"title":"Menstrual and psychosocial characteristics associated with high-risk of premenstrual dysphoric disorder among university students: a cross-sectional study.","authors":"Jung Jae Lee, Tongyao Wang, Jeongok Park, Bohee Lee, Hyojin Lee, Polly Wai Chi Li, Edmond Pui Hang Choi","doi":"10.1080/03630242.2024.2304899","DOIUrl":"10.1080/03630242.2024.2304899","url":null,"abstract":"Up to 92 percent of Chinese women of reproductive age have pre-menstrual syndrome (PMS). The severe form of PMS (i.e. pre-menstrual dysphoric disorder [PMDD]) negatively affects women's everyday functioning and reproductive health. This study examined the relationships between menstrual, psychosocial characteristics and the risk of PMDD among young Chinese women. A cross-sectional online survey was conducted among Chinese university students in Hong Kong. Logistic regression was used to compute adjusted odds ratio (aOR) for the association of high-risk PMDD with menstrual and psychosocial characteristics. A total of 541 Chinese university students were recruited. Approximately 53 percent of female students were at high risk of developing PMDD. The high-risk PMDD group was significantly associated with a heavy volume of menstrual flow (aOR = 2.17, 95 percent CI 1.06-4.45), irregular menstrual cycle (1.72, 1.17-2.52), high dysmenorrhea (2.80, 1.95-4.04) and older ages of menarche (0.67, 0.45-0.98) in the menstrual characteristics. In the psychosocial characteristics, high-risk PMDD was significantly associated with symptoms of anxiety (2.19, 1.48-3.32) and depression (2.22, 1.48-3.32), high loneliness (1.94, 1.34-2.79) and low resilience (2.21, 1.52-3.23) levels. Additionally, resilience had a potential moderating effect on the associations between the high risk of PMDD and anxiety, depression and loneliness. The development and delivery of interventions that can enhance resilience and manage psychological distress would be beneficial for young Chinese women's reproductive health.","PeriodicalId":23972,"journal":{"name":"Women & Health","volume":" ","pages":"153-164"},"PeriodicalIF":1.6,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139547256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Influence of postdiagnostic aspirin use on clinical outcomes of women with breast cancer: a meta-analysis. 诊断后服用阿司匹林对乳腺癌妇女临床预后的影响：一项荟萃分析。

IF 1.6 4区医学

Women & Health Pub Date : 2024-02-07 Epub Date: 2024-01-30 DOI: 10.1080/03630242.2023.2293718

Chuanfeng Wu, Minmin Hu, Shuangling Zhang, Jian Zhang, Liqing Shen, Xueqing Shen

{"title":"Influence of postdiagnostic aspirin use on clinical outcomes of women with breast cancer: a meta-analysis.","authors":"Chuanfeng Wu, Minmin Hu, Shuangling Zhang, Jian Zhang, Liqing Shen, Xueqing Shen","doi":"10.1080/03630242.2023.2293718","DOIUrl":"10.1080/03630242.2023.2293718","url":null,"abstract":"We examined the association between postdiagnostic aspirin use and recurrence and disease-specific mortality among women with breast cancer in a meta-analysis. The PubMed, Embase, and Web of Science databases were searched to identify observational studies with longitudinal follow-ups according to the aim of the meta-analysis. Combining the results was achieved using a random-effects model that included inter-study heterogeneity. Fifteen cohort studies with 131,636 women with breast cancer were included. Based on a meta-analysis, women who took aspirin after being diagnosed with breast cancer had a lower risk of breast cancer recurrence (adjusted risk ratio [RR]: 0.77, 95 percent confidence interval [CI]: 0.63 to 0.95, P = .02; I2 = 72 percent) and breast cancer specific mortality (adjusted RR: 0.73, 95 percent CI: 0.60 to 0.90, P = .004; I2 = 80 percent) than those who did not use aspirin. The certainty of the evidence was rated using the Grading of Recommendations Assessment, Development, and Evaluations scoring system showed moderate certainty for both the outcomes because significant inconsistency was observed. In conclusion, aspirin use after diagnosis might be associated with reduced recurrence and disease-specific mortality in women with breast cancer.","PeriodicalId":23972,"journal":{"name":"Women & Health","volume":" ","pages":"94-108"},"PeriodicalIF":1.6,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139049428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Breastfeeding challenges and the impact of social support in Iranian Muslim mothers: A cross-sectional study. 母乳喂养的挑战和社会支持对伊朗穆斯林母亲的影响：一项横断面研究。

IF 1.6 4区医学

Women & Health Pub Date : 2024-02-07 Epub Date: 2024-01-30 DOI: 10.1080/03630242.2024.2304898

Sepideh Soltani, Mina Hosseinzadeh, Mojgan Mirghafourvand, Parvaneh Aghajari, Elaine Burns

{"title":"Breastfeeding challenges and the impact of social support in Iranian Muslim mothers: A cross-sectional study.","authors":"Sepideh Soltani, Mina Hosseinzadeh, Mojgan Mirghafourvand, Parvaneh Aghajari, Elaine Burns","doi":"10.1080/03630242.2024.2304898","DOIUrl":"10.1080/03630242.2024.2304898","url":null,"abstract":"Breast milk is the perfect food during infancy. Adequate support from family and health systems can be helpful to continue breastfeeding. This study aimed to determine the status of breastfeeding challenges and its relationship with social support and socio-demographic factors. In this correlational-descriptive study, 348 breastfeeding mothers were recruited using cluster random sampling from health care centers in Tabriz, Iran in 2022. Socio-demographic, breastfeeding challenges and social support questionnaires were used for data collection. Data were analyzed for descriptive and inferential statistics (Pearson correlation tests, independent t-test, one-way ANOVA and general linear model) using SPSS version 16. Difficulty in completing household tasks and breastfeeding at the same time (32.5 percent) was the most common challenge reported by mothers. There was an inverse and significant correlation between perceived social support and experiencing challenges (r = -0.199؛ p = .001). Based on the adjusted general linear model, with increasing social support, the score of breastfeeding challenges decreased (B = -0.165; 95 percent CI: -0.07-0.25, p < .001). Considering the relationship between perceived social support and the challenges experienced during breastfeeding, it can be concluded that adequate support from family along with training and guidance from health care providers can lead women to have better breastfeeding experiences and overcome breastfeeding problems.","PeriodicalId":23972,"journal":{"name":"Women & Health","volume":" ","pages":"142-152"},"PeriodicalIF":1.6,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139520628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0