World Journal of Urology最新文献

{"title":"Comment on:'' A systematic review and meta-analysis of alpha-adrenergic antagonists for the treatment of pain in chronic prostatitis''.","authors":"Yun Deng, Changhong Xu, Li Yang","doi":"10.1007/s00345-025-05693-3","DOIUrl":"https://doi.org/10.1007/s00345-025-05693-3","url":null,"abstract":"","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"43 1","pages":"308"},"PeriodicalIF":2.8,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144080838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the cost-effectiveness and evidence base for perioperative chemotherapy in muscle-invasive bladder cancer.","authors":"Takeshi Takahashi","doi":"10.1007/s00345-025-05681-7","DOIUrl":"https://doi.org/10.1007/s00345-025-05681-7","url":null,"abstract":"","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"43 1","pages":"310"},"PeriodicalIF":2.8,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144080844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Temperature variations with Ho: YAG and thulium fiber lasers, including advanced fragmentation pulse (AFP) technology: an experimental analysis.","authors":"Nariman Gadzhiev, Aram Aloyan, Ivan Gorgotsky, Nikolai Piven, Alexey Martov, Vineet Gauhar, Selcuk Güven","doi":"10.1007/s00345-025-05675-5","DOIUrl":"https://doi.org/10.1007/s00345-025-05675-5","url":null,"abstract":"<p><strong>Purpose: </strong>Recent developments in high-power systems and the super-pulsed thulium fiber laser (TFL) promise enhanced efficiency but raise concerns about thermal safety. This study examines the intrarenal temperature profiles of Ho: YAG and TFL systems including the advanced fragmentation pulse (AFP) mode under simulated conditions.</p><p><strong>Methods: </strong>A custom-designed kidney and ureter model was used to measure intrarenal temperature changes during laser activation. Real-time temperature data were recorded via thermocouples placed in collecting system. Results were analyzed to compare water temperature increases with the safety threshold of 43 °C.</p><p><strong>Results: </strong>At an irrigation flow rate of 23 mL/min and an initial water temperature of 22 ± 1 °C, WTIs for all laser systems remained below the safety threshold of temperature increase (STTI) during 60 s of laser activation. Ho: YAG consistently demonstrated the lowest WTIs, whereas TFL in AFP mode showed higher WTIs comparable to Ho: YAG but lower compared to TFL standard mode. Across all settings, WTIs were highest in the pelvis due to proximity to the laser fiber, with lower values in the upper and lower poles. The rapid temperature rise observed in the first 10-15 s was followed by a slower, steady increase. These findings confirm that with proper irrigation, even high-power laser lithotripsy systems, including TFL with AFP, operate within thermally safe limits.</p><p><strong>Conclusion: </strong>This study confirms that both Ho: YAG and TFL systems, including AFP mode, remain thermally safe with adequate irrigation (23 mL/min) during 60-second activation sessions.</p>","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"43 1","pages":"309"},"PeriodicalIF":2.8,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144080925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prospective randomized study on the efficacy of tamsulosin, solifenacin, and their combination in relieving lower urinary tract symptoms in ureteric stent patients: insights from the brief-form Chinese USSQ.","authors":"Peter Hanna, Mohamed A Fahmy, Mohamed M Hussein, Amr Alam El-Din","doi":"10.1007/s00345-025-05695-1","DOIUrl":"10.1007/s00345-025-05695-1","url":null,"abstract":"<p><strong>Purpose: </strong>Assess the efficacy of selective alpha-1 blocker (tamsulosin) and antimuscarinic (solifenacin) as well as their combination in alleviating lower urinary tract symptoms in patients with ureteric stents using the brief-form Chinese version of the USSQ.</p><p><strong>Methods: </strong>A prospective randomized control study was conducted from May 2023 to October 2024 in the Urology department at Aswan University Hospital involving 160 consecutive patients undergoing DJ insertion after uncomplicated ureteroscopy. All patients are randomized into 4 groups receiving different treatments. Groups A, B, C, and D received a placebo, tamsulosin 0.4 mg, solifenacin 5 mg, and combinations respectively. IPSS and USSQ (brief-version) were collected and analyzed on the 1st day, 1st week, and 3rd week postoperative.</p><p><strong>Results: </strong>In all, 158 patients completed the study, 39 patients for Group A and Group B, while 40 patients for Group C and Group D. Baseline characteristics were comparable among all groups. Group (D) showed a significant decrease in mean ± (SD) IPSS 9.5 (± 1.4), and 7.7 (± 1.3) on 1st week and 3rd week postoperative respectively. Regarding USSQ, group (D) showed significantly lower scores compared to groups (A), (B), and (C) on the 1st day, 1st week, and 3rd week postoperatively (p < 0.001, p < 0.001, p < 0.001; respectively).</p><p><strong>Conclusion: </strong>The brief-form USSQ is a useful, reliable substitute for evaluating stent-related symptoms. Our findings support the notion that tamsulosin/solifenacin combinations have considerably reduced LUTS linked to the placement of ureteral stents.</p>","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"43 1","pages":"313"},"PeriodicalIF":2.8,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12084230/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144085755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Video-assisted education for informed consent in percutaneous nephrolithotomy: a prospective study on patient comprehension.","authors":"Mucahit Gelmis, Yasar Pazir, Ufuk Caglar, Ahmet Halis, Caglar Dizdaroglu, Furkan Gunay, Sedat Cakmak, Faruk Ozgor","doi":"10.1007/s00345-025-05690-6","DOIUrl":"10.1007/s00345-025-05690-6","url":null,"abstract":"<p><strong>Purpose: </strong>The prevalence of urinary stone disease is increasing due to climate change, dietary habits, and obesity. Percutaneous nephrolithotomy (PCNL) remains the preferred treatment for large kidney stones. The informed consent process is essential for patient understanding; however, conventional verbal and written methods may be inadequate. This study aimed to evaluate the effectiveness of video-assisted education in improving informed consent for PCNL.</p><p><strong>Methods: </strong>This randomized controlled study was conducted from January to July 2023. Eighty patients scheduled for PCNL were randomly assigned to either a written-consent-only group or a video-assisted consent group that received both written consent and a seven-minute 3D-animated video. Comprehension was assessed using a 17-question knowledge assessment questionnaire before and after the consent process. Improvements in knowledge and differences in comprehension were compared.</p><p><strong>Results: </strong>The video-assisted consent group showed significantly greater comprehension improvement than the written-only group, benefiting patients across all education levels. Multivariate analysis confirmed the strong association between video education and knowledge gain, though older age was linked to lower improvement. Despite its effectiveness, two patients withdrew due to increased anxiety, underscoring the need to balance understanding with emotional reassurance.</p><p><strong>Conclusion: </strong>Video-assisted informed consent significantly improves comprehension in PCNL patients, particularly in those with lower education levels. However, an increased awareness of surgical risks may contribute to preoperative anxiety. Future research should refine video content, assess long-term outcomes, and explore strategies to balance comprehension with emotional reassurance.</p>","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"43 1","pages":"305"},"PeriodicalIF":2.8,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144080927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the editor for the article \"influence of metastatic sites and burden on oncological outcomes in patients progressing to metastatic castration resistant prostate cancer\".","authors":"Yi Zhang, Shaoping Feng, Yao Shi, Jianfeng Chen, Zhigang Zhou, Chenghua Zhu","doi":"10.1007/s00345-025-05682-6","DOIUrl":"https://doi.org/10.1007/s00345-025-05682-6","url":null,"abstract":"","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"43 1","pages":"304"},"PeriodicalIF":2.8,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144080923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Platelet-rich plasma intra-plaque injections rapidly reduce penile curvature and improve sexual function in Peyronie's disease patients: results from a prospective large-cohort study.","authors":"Giuseppe Dachille, Andrea Panunzio, Leonardo Bizzotto, Maria Valeria D'Agostino, Federico Greco, Giuseppe Guglielmi, Umberto Carbonara, Marco Spilotros, Claudia Citarella, Angelo Ostuni, Giuseppe Lucarelli, Pasquale Ditonno, Alessandro Tafuri","doi":"10.1007/s00345-025-05691-5","DOIUrl":"https://doi.org/10.1007/s00345-025-05691-5","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate efficacy and safety of platelet-rich plasma (PRP) intra-plaque injections in Peyronie's disease (PD) patients.</p><p><strong>Methods: </strong>Three injections of 6 mL PRP were performed two weeks apart. Patients were evaluated at baseline (T0, first injection), after two weeks (T1, second injection), and four weeks after the third injection (T2). The curvature angle of the erect penis, plaque size, dedicated sexual function questionnaires (PD questionnaire-PDQ, and International Index of Erectile Function five-items - IIEF-5) scores, and adverse events/side effects were evaluated.</p><p><strong>Results: </strong>Overall, 72 patients were included. Median age was 60 years, and median BMI was 23.1 kg/m². Plaques were more frequently located at the middle third of the penis (n = 43); penile curvature direction was more frequently dorsal (n = 45). During follow up median plaque size decreased from 11.1 mm at T0 to 8.2 mm at T2 (p = 0.004), and median penile curvature decreased from 50.0° at T0 to 40.0° at T2 (p < 0.001). At the same timepoints, a statistically significant reduction was observed for all the three domains of the PDQ (PDQ1:p = 0.006, PDQ2:p = 0.002, PDQ3:p < 0.001), but not for the IIEF-5 (p = 0.3). At univariable linear regression analysis, testing the association between BMI and median penile curvature difference from the first and last evaluation, a tendency towards statistical significance was observed (β = -1.28, p = 0.055). No adverse events/side effect were registered.</p><p><strong>Conclusion: </strong>PRP is a safe and effective treatment option in men with PD, rapidly reducing plaques size and penile curvature angle, thus positively influencing sexual function. The higher the BMI the lower benefit might be derived from PRP injection.</p>","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"43 1","pages":"306"},"PeriodicalIF":2.8,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144080924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ageing patients, missing evidence: the need for more research in the elderly.","authors":"Patrick Juliebø-Jones, Stephen Baug, Lazaros Tzelves, Christian Beisland","doi":"10.1007/s00345-025-05688-0","DOIUrl":"https://doi.org/10.1007/s00345-025-05688-0","url":null,"abstract":"","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"43 1","pages":"303"},"PeriodicalIF":2.8,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144080837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can suction alone explain improved better stone free rate in percutaneous nephrolithotomy?","authors":"Behnam Shakiba, Vahid Vahedi","doi":"10.1007/s00345-025-05684-4","DOIUrl":"https://doi.org/10.1007/s00345-025-05684-4","url":null,"abstract":"","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"43 1","pages":"302"},"PeriodicalIF":2.8,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143989346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postoperative pain evaluation in laparoscopic radical prostatectomy surgery using tranexamic acid: analgesia?, hyperalgesia??","authors":"Gülten Arslan, Nihan Yaman Mammadov, Ceren Önal, Fırat Mavi, Fatih Doğu Geyik, Banu Eler Çevik","doi":"10.1007/s00345-025-05581-w","DOIUrl":"10.1007/s00345-025-05581-w","url":null,"abstract":"<p><strong>Purpose: </strong>Tranexamic acid(TXA), an antifibrinolytic agent, is widely used to reduce bleeding, but its effect on pain is not clear.The purpose of this study was to evaluate the effectiveness of intravenous TXA on postoperative pain and bleeding in patients undergoing laparoscopic radical prostatectomy(LRP).</p><p><strong>Methods: </strong>Our study was conducted as a prospective, observational study. Seventy patients aged 18-75years, ASA II-III, who would undergo LRP surgery under general anesthesia were included in the study.After anaesthesia induction, maintenance was provided with desflurane and 0.1-0.5mcg/kg/min remifentanil infusion with BIS monitoring.The control group(Group C) (n = 35) received 100 ml of saline and the study group(Group TXA) (n = 35) received TXA 15 mg/kg bolus 10 min before the incision and then 100 mg/hour infusion until skin closure. Demographic, hemodynamic data, ASA, education level, duration of operation and anesthesia, bleeding, administered fluid and remifentanil amounts, hemoglobin values(at the beginning of the operation, 2nd hours, end of the operation, postoperative 12th, 24th hours), Visual Analog Scale (VAS) (at 0th, 6th, 12th, 24th hours postoperatively), time to first rescue analgesia requirement, number of rescue analgesia used within 24h and side effects were recorded.</p><p><strong>Results: </strong>It was observed that VAS scores were statistically higher in TXA group at postoperative 0th and 6th hours, postoperative rescue analgesia requirement was higher and first rescue analgesia requirement time was shorter. No difference was determined between the groups in terms of other parameters.</p><p><strong>Conclusion: </strong>In our study, we concluded that there was no significant difference in terms of bleeding in patients who were administered TXA, but this agent may cause hyperalgesia and a special approach to analgesia should be taken in cases where it is decided to be used.</p><p><strong>Clinical trials: </strong>GOV : (NCT06040853).</p>","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"43 1","pages":"300"},"PeriodicalIF":2.8,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12075332/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144031577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}