World Journal of Urology最新文献

筛选
英文 中文
Should percutaneous nephrolithotomy be performed in patients with severe chronic kidney disease? A closer look at renal function outcomes. 严重慢性肾病患者是否应行经皮肾镜取石术?仔细观察肾功能结果。
IF 2.9 2区 医学
World Journal of Urology Pub Date : 2025-09-03 DOI: 10.1007/s00345-025-05906-9
Vinay Durbhakula, Ziv Savin, Eve Frangopoulos, Asher Mandel, Linda Dayan Rahmani, Adam Daniel Geffner, Esther Kim, Aubrey Dibello, Blair Gallante, William M Atallah, Mantu Gupta
{"title":"Should percutaneous nephrolithotomy be performed in patients with severe chronic kidney disease? A closer look at renal function outcomes.","authors":"Vinay Durbhakula, Ziv Savin, Eve Frangopoulos, Asher Mandel, Linda Dayan Rahmani, Adam Daniel Geffner, Esther Kim, Aubrey Dibello, Blair Gallante, William M Atallah, Mantu Gupta","doi":"10.1007/s00345-025-05906-9","DOIUrl":"https://doi.org/10.1007/s00345-025-05906-9","url":null,"abstract":"","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"43 1","pages":"533"},"PeriodicalIF":2.9,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Can intraoperative endoscopic evaluation replace postoperative low-dose CT for assessing the stone-free status in vacuum-assisted dedusting lithotripsy. 术中内镜评估是否可以取代术后低剂量CT评估真空除尘碎石中无结石状态?
IF 2.9 2区 医学
World Journal of Urology Pub Date : 2025-09-03 DOI: 10.1007/s00345-025-05911-y
Qi Liu, Junkai Huang, Jian Li, Xuanhao Zhang, Yue Zheng, Chunyu Liu, Haijie Xie
{"title":"Can intraoperative endoscopic evaluation replace postoperative low-dose CT for assessing the stone-free status in vacuum-assisted dedusting lithotripsy.","authors":"Qi Liu, Junkai Huang, Jian Li, Xuanhao Zhang, Yue Zheng, Chunyu Liu, Haijie Xie","doi":"10.1007/s00345-025-05911-y","DOIUrl":"10.1007/s00345-025-05911-y","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the diagnostic accuracy of intraoperative endoscopic assessment with postoperative low-dose computed tomography (LDCT) for determining stone-free status (SFS) following retrograde vacuum-assisted dedusting lithotripsy (VADL) using a tip-flexible vacuum-assisted suction ureteral access sheath (tFVS-UAS) and evaluate the feasibility of replacing routine LDCT with intraoperative evaluation.</p><p><strong>Methods: </strong>This single-center retrospective study analyzed 1,105 patients undergoing unilateral VADL (December 2022-December 2024). All VADL procedures were performed retrograde using tFVS-UAS. Postoperative LDCT on day 30 served as the reference standard. Agreement between intraoperative endoscopic assessment and LDCT was evaluated using McNemar's test and Kappa statistics. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were calculated.</p><p><strong>Results: </strong>The overall stone-free rate (SFR) was 83.35% (89.89% for stones ≤ 20 mm; 63.50% for stones > 20 mm). Intraoperative assessment demonstrated high specificity (98.70%, 95% CI: 97.80-99.60%) but low sensitivity (43.48%, 95% CI: 36.35-50.61%), with an NPV of 89.73% and PPV of 86.96%. Subgroup analysis revealed stronger agreement for stones ≤ 20 mm (Kappa = 0.61, NPV = 94.40%) compared to stones > 20 mm (Kappa = 0.40, sensitivity = 40.00%)(Bonferroni-adjusted α = 0.025).</p><p><strong>Conclusion: </strong>Intraoperative endoscopic assessment during VADL reliably confirms SFS for stones ≤ 20 mm, potentially reducing the utilization of postoperative LDCT in low-risk patients when SFS is endoscopically verified. However, LDCT remains essential for stones > 20 mm or high-risk scenarios due to limited sensitivity. Clinical implementation requires risk stratification and shared decision-making.</p>","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"43 1","pages":"537"},"PeriodicalIF":2.9,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Routine annual imaging does not aid in diagnosing new functional complications more than five years after RC with ileal conduit. 常规年度影像学检查不能帮助诊断回肠导管切除术后5年内新的功能并发症。
IF 2.9 2区 医学
World Journal of Urology Pub Date : 2025-09-03 DOI: 10.1007/s00345-025-05903-y
Joanneke B Ringia, Femke E F Scholte, Renee A G Lijnen, Emma Algie, Sarah M H Einerhand, Esther M K Wit, Maaike W van de Kamp, Thierry N Boellaard, Henk G van der Poel, Bas W G van Rhijn, Laura S Mertens, Kees Hendricksen
{"title":"Routine annual imaging does not aid in diagnosing new functional complications more than five years after RC with ileal conduit.","authors":"Joanneke B Ringia, Femke E F Scholte, Renee A G Lijnen, Emma Algie, Sarah M H Einerhand, Esther M K Wit, Maaike W van de Kamp, Thierry N Boellaard, Henk G van der Poel, Bas W G van Rhijn, Laura S Mertens, Kees Hendricksen","doi":"10.1007/s00345-025-05903-y","DOIUrl":"10.1007/s00345-025-05903-y","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the value of routine annual imaging in identifying complications more than 5 years after radical cystectomy (RC) with ileal conduit.</p><p><strong>Methods: </strong>We included patients with bladder cancer who underwent RC with ileal conduit between 2011 and 2018. Patients were excluded if they received no functional follow up after discontinuing oncological follow up, if there was oncological progression or if an uretero-enteric structure (UES) was diagnosed within 5 years after RC. Functional follow up consisted of annual imaging using either ultrasound or CT, along with laboratory tests. The primary outcomes were: (1) the incidence of new or progressive hydronephrosis, and (2) the incidence of imaging-diagnosed complications i.e. UES and urolithiasis.</p><p><strong>Results: </strong>A total of eighty-two patients were included, with a mean follow up of 6.5 years after RC. In total, 202 ultrasounds and 71 CTs were performed. New or progressive hydronephrosis was observed in 6 imaging modalities (2.2%), in 6 different patients (7.3%). No UES cases were diagnosed following routine annual imaging. One patient was diagnosed with UES after diagnostic imaging was prompted by clinical symptoms.</p><p><strong>Conclusion: </strong>In our cohort, routine annual imaging beyond five years after radical cystectomy (RC) with ileal conduit rarely revealed abnormalities and did not contribute to the diagnosis of UES nor urolithiasis. However, imaging should be performed when clinically indicated.</p>","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"43 1","pages":"539"},"PeriodicalIF":2.9,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy, feasibility, and safety of aquablation after previous urolift treatment of lower urinary tract symptoms secondary to benign prostate hyperplasia: a retrospective cohort study. 既往尿路提升治疗继发于良性前列腺增生的下尿路症状后水消融的有效性、可行性和安全性:一项回顾性队列研究
IF 2.9 2区 医学
World Journal of Urology Pub Date : 2025-09-03 DOI: 10.1007/s00345-025-05897-7
Hashem Darwazeh, Keng Lim Ng, Neil Barber
{"title":"Efficacy, feasibility, and safety of aquablation after previous urolift treatment of lower urinary tract symptoms secondary to benign prostate hyperplasia: a retrospective cohort study.","authors":"Hashem Darwazeh, Keng Lim Ng, Neil Barber","doi":"10.1007/s00345-025-05897-7","DOIUrl":"10.1007/s00345-025-05897-7","url":null,"abstract":"<p><strong>Purpose: </strong>The influence of a previous Urolift treatment on the outcomes of prostate Aquablation is still controversial. This retrospective cohort study aimed to evaluate the perioperative outcomes, efficacy, feasibility, and safety of Aquablation after previous Urolift treatment.</p><p><strong>Methods: </strong>The charts of patients with benign prostate hyperplasia (BPH) complicated by storage and voiding symptoms, who were previously treated with Urolift followed by Aquablation between January 2022 and July 2024, were retrospectively reviewed and analyzed for changes in International Prostate Symptom Score (IPSS), maximum urinary flow rates (Qmax), and postvoid residual volume (PVR) from baseline (pre-Aquablation) to the mean of three months postoperatively. Day-case surgery was performed in 75% of the cases.</p><p><strong>Results: </strong>The study included 40 patients with a mean age of 68 (SD ± 8.91) years with moderately enlarged prostates (mean volume 81.56 mL, (SD ± 25.32), and median PSA 3.2 ng/dL). Five patients were presented initially with an indwelling Foley catheter, so their data were not included in the statistical analysis. After Aquablation, the mean IPSS improved from 24.7 (SD ± 7.63) at baseline to 9.8 (SD ± 2.55) (p < 0.0001), the mean Qmax increased from 9.6mL/sec (SD ± 5.76) at baseline to 20.8mL/sec (SD ± 6.28) (p < 0.0001), and the mean PVR decreased from 143mL (SD ± 104.89) at baseline to 36mL (SD ± 30.63 ) (p < 0.0001). The hospital stay for patients admitted ranged from 1 to 2 days. Moreover, there were no major intraoperative difficulties removing dislodged Urolift clips with a loop resectoscope at the end of the procedure, while non-dislodged clips were left in situ. None of the patients had postoperative bleeding that required hospital admission or blood transfusion following discharge.</p><p><strong>Conclusion: </strong>Based on these results, prostate Aquablation appeared to be an effective, safe, feasible, and reliable surgical procedure for BPH patients who have had previous Urolift treatment. Further prospective and larger scale studies are needed.</p>","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"43 1","pages":"535"},"PeriodicalIF":2.9,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12408747/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognostic significance of perineural invasion and lymphovascular invasion following robot-assisted radical prostatectomy with negative surgical margins: a retrospective study from a high-volume center. 机器人辅助阴性切缘根治性前列腺切除术后神经周围浸润和淋巴血管浸润的预后意义:一项来自大容量中心的回顾性研究。
IF 2.9 2区 医学
World Journal of Urology Pub Date : 2025-09-03 DOI: 10.1007/s00345-025-05749-4
Yu Ozawa, Rohan Sharma, Marcio Covas Moschovas, Shady Saikali, Ahmed Gamal, Marco Sandri, Travis Rogers, Vipul Patel
{"title":"Prognostic significance of perineural invasion and lymphovascular invasion following robot-assisted radical prostatectomy with negative surgical margins: a retrospective study from a high-volume center.","authors":"Yu Ozawa, Rohan Sharma, Marcio Covas Moschovas, Shady Saikali, Ahmed Gamal, Marco Sandri, Travis Rogers, Vipul Patel","doi":"10.1007/s00345-025-05749-4","DOIUrl":"10.1007/s00345-025-05749-4","url":null,"abstract":"<p><strong>Purpose: </strong>Perineural invasion (PNI) and lymphovascular invasion (LVI) represent tumor escape mechanisms at radical prostatectomy (RP). We assessed their prognostic significance for biochemical recurrence (BCR) following complete resection.</p><p><strong>Methods: </strong>We analyzed 10,471 men with negative surgical margins after RP, stratified into three groups based on pathological PNI and LVI status: Group 1 (PNI-/LVI-, n = 1,925), Group 2 (PNI+/LVI-, n = 7,849), and Group 3 (LVI+, n = 697; 14 with PNI-/LVI + and 683 with PNI+/LVI+). The cumulative probability of BCR (PSA > 0.2 ng/mL after initial undetectable level), cancer-specific mortality, and all-cause mortality were compared using Kaplan-Meier curves and log-rank tests. Multivariable Cox regression adjusted for age, race, comorbidity, PSA at biopsy, final grade group, pathological T and N stage, and tumor diameter.</p><p><strong>Results: </strong>The median follow-up was 60 months (IQR: 18-108). Pathological N1 disease was more frequent in Group 3 (5.7%) than in Group 1 (0.1%) and Group 2 (0.3%). Compared with Group 1, the unadjusted hazard ratios (HRs) for BCR were 6.07 (95% CI: 4.30-8.56) in Group 2 and 23.4 (95% CI: 16.3-33.6) in Group 3; adjusted HRs were 2.51 (95% CI: 1.76-3.58) and 3.79 (95% CI: 2.55-5.53), respectively. Mortality outcomes were comparable across groups, both before and after the adjustment.</p><p><strong>Conclusion: </strong>Our study demonstrated that the combination of PNI and LVI independently predicted BCR following complete resection. Their integration into postoperative risk assessment may improve BCR prediction and guide individualized follow-up planning. Longer follow-up is required to draw definitive conclusions regarding their impact on mortality outcomes.</p>","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"43 1","pages":"536"},"PeriodicalIF":2.9,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radical nephroureterectomy vs kidney sparing surgery for upper tract urothelial carcinoma in solitary kidney patients: a multi-institutional analysis of the ROBUUST 2.0 registry. 根治性肾输尿管切除术与肾保留手术治疗孤立肾患者上尿路上皮癌:robust2.0注册的多机构分析
IF 2.9 2区 医学
World Journal of Urology Pub Date : 2025-09-03 DOI: 10.1007/s00345-025-05882-0
Francesco Ditonno, Alessandro Veccia, Gabriele Bignante, Zhenjie Wu, Linhui Wang, Firas Abdollah, Alex Stephens, Giuseppe Simone, Gabriele Tuderti, Randall Lee, Daniel D Eun, Andres F Correa, Ottavio De Cobelli, Matteo Ferro, Francesco Porpiglia, Daniele Amparore, Enrico Checcucci, Antonio Tufano, Roberto Contieri, Sisto Perdonà, Raj Bhanvadia, Vitaly Margulis, Stephan Brönimann, Nirmish Singla, James Porter, Saum Ghodoussipour, Andrea Minervini, Andrea Mari, Luca Lambertini, Alireza Ghoreifi, Omri Falik Nativ, Mark L Gonzalgo, Daniel Sidhom, Chandru P Sundaram, Reuben Ben-David, Ahmed Eraky, Reza Mehrazin, Takashi Yoshida, Hidefumi Kinoshita, Alireza Dehghanmanshadi, Soroush Rais-Bahrami, Margaret F Meagher, Dhruv Puri, Ithaar H Derweesh, Farshad S Moghaddam, Hooman Djaladat, Riccardo Bertolo, Riccardo Autorino, Alessandro Antonelli
{"title":"Radical nephroureterectomy vs kidney sparing surgery for upper tract urothelial carcinoma in solitary kidney patients: a multi-institutional analysis of the ROBUUST 2.0 registry.","authors":"Francesco Ditonno, Alessandro Veccia, Gabriele Bignante, Zhenjie Wu, Linhui Wang, Firas Abdollah, Alex Stephens, Giuseppe Simone, Gabriele Tuderti, Randall Lee, Daniel D Eun, Andres F Correa, Ottavio De Cobelli, Matteo Ferro, Francesco Porpiglia, Daniele Amparore, Enrico Checcucci, Antonio Tufano, Roberto Contieri, Sisto Perdonà, Raj Bhanvadia, Vitaly Margulis, Stephan Brönimann, Nirmish Singla, James Porter, Saum Ghodoussipour, Andrea Minervini, Andrea Mari, Luca Lambertini, Alireza Ghoreifi, Omri Falik Nativ, Mark L Gonzalgo, Daniel Sidhom, Chandru P Sundaram, Reuben Ben-David, Ahmed Eraky, Reza Mehrazin, Takashi Yoshida, Hidefumi Kinoshita, Alireza Dehghanmanshadi, Soroush Rais-Bahrami, Margaret F Meagher, Dhruv Puri, Ithaar H Derweesh, Farshad S Moghaddam, Hooman Djaladat, Riccardo Bertolo, Riccardo Autorino, Alessandro Antonelli","doi":"10.1007/s00345-025-05882-0","DOIUrl":"10.1007/s00345-025-05882-0","url":null,"abstract":"<p><strong>Purpose: </strong>Radical nephroureterectomy (RNU) for upper tract urothelial carcinoma (UTUC) in solitary kidney patients is a rare and underreported scenario. This study aims to compare the outcomes of UTUC solitary kidney patients becoming anephric after RNU to those of patients undergoing kidney-sparing surgery (KSS).</p><p><strong>Methods: </strong>Data from patients with a solitary kidney were retrieved from the ROBUUST 2.0 database, a global, multicenter registry containing data on patients who underwent curative surgery for UTUC. Baseline patient demographics, disease characteristics, and surgical features were compared between RNU and KSS. Kaplan-Meier methods were used to estimate recurrence-free survival (RFS), metastasis-free survival (MFS), cancer-specific survival (CSS), and overall survival (OS) in patients undergoing RNU, with 3-year and 5-year cutoffs applied.</p><p><strong>Results: </strong>Thirty-nine patients (76.5%) underwent RNU, whereas 12 (23.5%) underwent KSS. Despite a comparable preoperative renal function, the distribution of CKD stages differed significantly between the groups (p = 0.019). Despite a similar rate of postoperative complications, patients undergoing RNU experienced a significantly higher median LOS (p < 0.001). Among RNU patients, OS was 83.9%, CSS was 96.9%, RFS was 71.8%, and MFS was 84.4% at the 3-year follow-up. After 5 years post-surgery, OS was 73.4%, CSS was 83.1%, RFS was 59.9%, and MFS was 78.5% in the same cohort.</p><p><strong>Conclusions: </strong>UTUC solitary kidney patients undergoing RNU or KSS face a substantial perioperative burden. Despite these challenges, our cohort demonstrated favorable oncological outcomes comparable to those reported in the existing literature.</p>","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"43 1","pages":"534"},"PeriodicalIF":2.9,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12405301/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intelligent pressure-controlled ureteral access sheath combined with flexible ureteroscopy versus flexible ureteroscopy and percutaneous nephrolithotomy for renal stones less than 3 cm in diameter: a comparative efficacy study. 智能压力控制输尿管通路鞘联合输尿管软镜与输尿管软镜联合经皮肾镜取石治疗直径小于3cm肾结石的疗效比较研究
IF 2.9 2区 医学
World Journal of Urology Pub Date : 2025-09-03 DOI: 10.1007/s00345-025-05907-8
Yunduo Fan, Chenyu Miao, Yuanxiao Li, Bin Li, Shengxian Li
{"title":"Intelligent pressure-controlled ureteral access sheath combined with flexible ureteroscopy versus flexible ureteroscopy and percutaneous nephrolithotomy for renal stones less than 3 cm in diameter: a comparative efficacy study.","authors":"Yunduo Fan, Chenyu Miao, Yuanxiao Li, Bin Li, Shengxian Li","doi":"10.1007/s00345-025-05907-8","DOIUrl":"https://doi.org/10.1007/s00345-025-05907-8","url":null,"abstract":"","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"43 1","pages":"538"},"PeriodicalIF":2.9,"publicationDate":"2025-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Post-surgical outcomes in transgender women: a prospective analysis of sexual function and health-related quality of life. 变性女性术后结局:性功能与健康相关生活质量的前瞻性分析
IF 2.9 2区 医学
World Journal of Urology Pub Date : 2025-09-02 DOI: 10.1007/s00345-025-05887-9
M J Wenk, N Rademacher, B Liedl, B Grüne, B Meister
{"title":"Post-surgical outcomes in transgender women: a prospective analysis of sexual function and health-related quality of life.","authors":"M J Wenk, N Rademacher, B Liedl, B Grüne, B Meister","doi":"10.1007/s00345-025-05887-9","DOIUrl":"10.1007/s00345-025-05887-9","url":null,"abstract":"<p><strong>Purpose: </strong>To prospectively evaluate patient and clinician reported outcomes of sexual function and health-related quality of life (QOL) of transgender women preoperatively (t0), 6 months (t1), and 12 months (t2) after gender-affirming surgery (GAS) with penile inversion vaginoplasty.</p><p><strong>Methods: </strong>Transgender women undergoing two-stage GAS at our tertiary care center were included (04/2019-01/2023). Patients received a composed questionnaire including a validated questionnaire (SF-12). Clinical outcomes and adverse events were evaluated. A regression analysis was performed to identify possible risk factors for a deterioration in sexual function and QOL.</p><p><strong>Results: </strong>Fifty-three patients with an average age of 40.27 ± 14.43 years were included. Complications were mostly minor (Clavien Dindo Classification grade I/II). The depth of the neovagina postoperatively was 11.98 ± 2.19 cm and the width 3.44 ± 0.98 cm. 79.4% of patients were able to experience an orgasm 12 months postoperatively. Orgasm quality increased significantly over the measurement time points (p = 0.003). The SF-12 average physical and mental scores of our collective were similar to the German populations average scores with no significant differences between the time measurement points (p = 0.405 and p = 0.198, respectively). The mental score was always lower than the physical score. A multiple linear regression analysis showed age < 40 years to be a significant influence factor regarding the physical QOL-score (p = 0.048) and the ability to experience an orgasm (p = 0.026).</p><p><strong>Conclusion: </strong>Penile inversion vaginoplasty is a safe procedure that yields favorable outcomes regarding sexual function and health-related QOL. Younger age significantly predicts improved physical QOL and the ability to experience orgasm postoperatively.</p>","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"43 1","pages":"529"},"PeriodicalIF":2.9,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12405499/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Flexible ureteroscopy in renal anomalies: an explainable AI model for surgical outcome prediction from EAU endourology. 肾异常的柔性输尿管镜:一种可解释的人工智能模型,用于EAU泌尿外科手术结果预测。
IF 2.9 2区 医学
World Journal of Urology Pub Date : 2025-09-02 DOI: 10.1007/s00345-025-05904-x
Carlotta Nedbal, Vineet Gauhar, Sairam Adithya, Nithesh Naik, Shilpa Gite, Het Sevalia, Daniele Castellani, Andrea Gregori, Frédéric Panthier, Yiloren Tanidir, Anil Shrestha, Vikram Sridharan, Abhishek Singh, Boyke Soebhali, Mohamed Amine Lakmichi, Saeed Biin Hamri, Bhaskar Kumar Somani
{"title":"Flexible ureteroscopy in renal anomalies: an explainable AI model for surgical outcome prediction from EAU endourology.","authors":"Carlotta Nedbal, Vineet Gauhar, Sairam Adithya, Nithesh Naik, Shilpa Gite, Het Sevalia, Daniele Castellani, Andrea Gregori, Frédéric Panthier, Yiloren Tanidir, Anil Shrestha, Vikram Sridharan, Abhishek Singh, Boyke Soebhali, Mohamed Amine Lakmichi, Saeed Biin Hamri, Bhaskar Kumar Somani","doi":"10.1007/s00345-025-05904-x","DOIUrl":"10.1007/s00345-025-05904-x","url":null,"abstract":"","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"43 1","pages":"530"},"PeriodicalIF":2.9,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12405343/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Donor site morbidity and impact on oral health following buccal mucosal graft harvesting for urethroplasty: a prospective study. 一项前瞻性研究:用于尿道成形术的颊粘膜移植术后供区发病率及其对口腔健康的影响。
IF 2.9 2区 医学
World Journal of Urology Pub Date : 2025-09-02 DOI: 10.1007/s00345-025-05898-6
Devang Desai, Sachin Joshi, Kapilan Ravichandran, Hannah Flynn, Stefan De Wachter, Gunter De Win
{"title":"Donor site morbidity and impact on oral health following buccal mucosal graft harvesting for urethroplasty: a prospective study.","authors":"Devang Desai, Sachin Joshi, Kapilan Ravichandran, Hannah Flynn, Stefan De Wachter, Gunter De Win","doi":"10.1007/s00345-025-05898-6","DOIUrl":"10.1007/s00345-025-05898-6","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate patient-reported oral health and pain and buccal donor site complications in adults who underwent BMG harvesting utilizing two validated questionnaires.</p><p><strong>Materials and methods: </strong>An ethics-approved prospective observational study was conducted among a cohort of 40 adults who had a BMG urethroplasty between June 2020 and October 2021. All cases were performed by one fellowship-trained genitourinary reconstructive surgeon. Oral health was appraised before and after BMG harvesting via the validated Oral Impacts of Daily Performance (OIDP) questionnaire. Post-operative pain at the BMG donor site was assessed by administering the Visual Analogue Scale for pain (VAS) both pre-and post-operatively. Statistical analysis was undertaken to identify risk factors for increased post-operative pain and decreased oral health.</p><p><strong>Results: </strong>The cohort included sub-meatal, penile, bulbar, and pan-urethral strictures. Most cases (36/40) were a primary urethroplasty, but 4 cases were a re-do urethroplasty. Only 5 participants (12.5%) experienced complication(s) at the donor site such as bleeding (2/40, 5%), infection (1/40, 2.5%), hyper granulation tissue (1/40, 2.5%), and long-term difficulty with mouth opening (3/40, 7.5%). Most participants (32/40, 80%) had at least one daily oral performance affected by BMG harvesting. Eating, speaking, and cleaning teeth were the most impacted domains. However, there was no statistically significant decrease in oral health at either 3- or 6 months post-BMG harvesting (p < 0.05). Almost all participants (38/40, 95%) reported no pain at the donor site before BMG harvesting. Pain at the donor site peaked at 1 week post-operatively (28/40, 70%), but the majority were pain-free by 3 months post-BMG harvesting (35/40, 87.5%).</p><p><strong>Conclusion: </strong>BMG harvesting is an effective means of procuring a suitable graft for urethroplasty. Whilst pain at the donor site is experienced in the immediate post-operative period, long-term pain is a rare complication. Overall oral health is not detrimentally impacted by BMG harvesting.</p>","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"43 1","pages":"531"},"PeriodicalIF":2.9,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144971694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信