World Journal of Urology最新文献

Algorithm to detect ISUP ≥ 2 prostate cancer using canine detection. 犬类检测ISUP≥2前列腺癌的算法。

IF 2.9 2区医学

World Journal of Urology Pub Date : 2025-09-11 DOI: 10.1007/s00345-025-05938-1

Margaux Hermieu, Alice Roux, Loïc Desquilbet, Nicolas Hermieu, Capucine Gallet, Evanguelos Xylinas, Alexandre de La Taille, Dominique Grandjean, Jean-François Hermieu

{"title":"Algorithm to detect ISUP ≥ 2 prostate cancer using canine detection.","authors":"Margaux Hermieu, Alice Roux, Loïc Desquilbet, Nicolas Hermieu, Capucine Gallet, Evanguelos Xylinas, Alexandre de La Taille, Dominique Grandjean, Jean-François Hermieu","doi":"10.1007/s00345-025-05938-1","DOIUrl":"https://doi.org/10.1007/s00345-025-05938-1","url":null,"abstract":"Purpose: Screening and diagnosing ISUP ≥ 2 prostate cancer is challenging. This study aimed to determine whether canine detection could be beneficial addition to the ISUP ≥ 2 prostate cancer diagnostic protocol by creating a decision-making algorithm for men with suspected prostate cancer.Methods: We conducted a prospective study at two urology institutions and a French veterinary school, including men with a suspicion of prostate cancer from November to April 2023, which were divided into two groups according to their prostate biopsy results. Eight binary variables known to be associated with a higher risk of prostate cancer were considered: body mass index, family history, age, smoking status, hypertension, digital rectal examination, total PSA level and prostate MRI. A decision-making algorithm was then created using two diagnostic scores.Results: 151 patients were included, 78 with ISUP ≥2 prostate cancer, and 73 without. The ProstateDetectScore was based on age, blood pressure, digital rectal examination, and MRI.[Formula: see text]Weight i is the whole part {rounded (10 x β i)} where β i is the model parameter value associated with the variable i included in this model and var ij is the value of variable i for patient j. The ProstateK9DetectScore is calculated from the same data plus the canine detection result. The following algorithm was constructed: PCa Prostate cancer, NPV negative predictive value, PPV positive predictive value CONCLUSION: The algorithm, involving canine detection, increases ISUP ≥2 prostate cancer detection rate through prostate biopsy, thus reducing the number of unnecessary biopsies.","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"43 1","pages":"549"},"PeriodicalIF":2.9,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145034249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comment on "PSA density correlates to pathology T stage and ISUP grade: insights from a cohort of 3568 radical rostatectomy cases". 评论“PSA密度与病理T分期和ISUP分级相关：来自3568例根治性前列腺切除术病例的见解”。

IF 2.9 2区医学

World Journal of Urology Pub Date : 2025-09-11 DOI: 10.1007/s00345-025-05934-5

Mohammad Taha Rahimipour, Ali Sedighi, Nima Masoudi

引用次数: 0

Endoscopic combined intrarenal surgery (ECIRS) versus supine percutaneous nephrolithotomy (S-PCNL): a propensity score matched study of surgical outcomes and complications. 内镜联合肾内手术（ECIRS）与仰卧经皮肾镜取石术（S-PCNL）：手术结果和并发症的倾向评分匹配研究

IF 2.9 2区医学

World Journal of Urology Pub Date : 2025-09-11 DOI: 10.1007/s00345-025-05913-w

T Fonseka, G Basile, L Ongaro, S Bhat, L Logrado, F Dionisio, D Allen, P Singh, A Goyal, G Ellis, R Kucheria, A Goode, D Yu, L Ajayi

{"title":"Endoscopic combined intrarenal surgery (ECIRS) versus supine percutaneous nephrolithotomy (S-PCNL): a propensity score matched study of surgical outcomes and complications.","authors":"T Fonseka, G Basile, L Ongaro, S Bhat, L Logrado, F Dionisio, D Allen, P Singh, A Goyal, G Ellis, R Kucheria, A Goode, D Yu, L Ajayi","doi":"10.1007/s00345-025-05913-w","DOIUrl":"https://doi.org/10.1007/s00345-025-05913-w","url":null,"abstract":"Purpose: Endoscopic Combined Intrarenal Surgery (ECIRS) has transformed the management of complex renal stones, offering potential advantages over conventional Percutaneous Nephrolithotomy (PCNL), including reduced need for secondary punctures and improved stone-free rates (SFR). This study aimed to compare surgical outcomes and complications between ECIRS and Supine PCNL (S-PCNL).Methods: Data was prospectively collected from all consecutive patients treated with ECIRS or S-PCNL at a UK tertiary centre from 2008 to 2024. Surgical outcomes, complications, transfusion rates, and hospital stay were recorded. A 1:1 propensity score matching (PSM) method was used to minimize differences in baseline characteristics. The primary outcome was secondary puncture rate; secondary outcomes included SFR, complication rates, operative time, transfusion rate, and hospital stay.Results: A total of 704 patients were included, with 186 (26%) undergoing ECIRS. After PSM, 176 matched pairs were analysed. ECIRS showed a significantly lower secondary puncture rate (2% vs. 7%, p = 0.01) and higher SFR (90% vs. 81%, p = 0.01). There were no significant differences in overall (16% vs. 14%, p = 0.7) or major complications (6% vs. 4.5%, p = 0.8), or in transfusion rates (0.6% vs. 1.1%, p = 0.7). ECIRS had a longer median operative time [72 vs. 65 min, p = 0.03], while S-PCNL was associated with a longer hospital stay [3 vs. 2 days, p = 0.02].Conclusions: ECIRS is a safe and effective technique for managing complex renal stones. The technique is associated with higher stone free rate and reduced need for secondary puncture compared to S-PCNL.","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"43 1","pages":"550"},"PeriodicalIF":2.9,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145034277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ergonomics in percutaneous nephrolithotomy: a comparative analysis of musculoeskeletical and mental workload in prone vs. supine positions with two lithotripters-a pilot study. 经皮肾镜取石术的人体工程学：两种碎石机在俯卧位和仰卧位时肌肉骨骼和精神负荷的比较分析——一项初步研究。

IF 2.9 2区医学

World Journal of Urology Pub Date : 2025-09-09 DOI: 10.1007/s00345-025-05922-9

Diego González, Catherine Sánchez, Christian Segovia, Tomas Gatica, Smita De, Felipe Pauchard, Gastón M Astroza, José A Salvadó, Juan Fulla

{"title":"Ergonomics in percutaneous nephrolithotomy: a comparative analysis of musculoeskeletical and mental workload in prone vs. supine positions with two lithotripters-a pilot study.","authors":"Diego González, Catherine Sánchez, Christian Segovia, Tomas Gatica, Smita De, Felipe Pauchard, Gastón M Astroza, José A Salvadó, Juan Fulla","doi":"10.1007/s00345-025-05922-9","DOIUrl":"https://doi.org/10.1007/s00345-025-05922-9","url":null,"abstract":"Purpose: Percutaneous nephrolithotomy (PCNL) is a common technique in the surgical management of renal lithiasis, but it also represents a significant workload for surgeons. Factors such as the patient's position and the type of lithotripter used influence the physical and mental load on the surgeon. The study aimed to identify stressors related to PCNL by comparing the physical and mental workload experienced by urologists during PCNL under different patient positions and using two lithotripters.Methods: Four expert endourologists were evaluated when simulating PCNL at four different conditions: prone and supine, using the Lithoclast Master (LM) or Lithoclast Trilogy (LT) devices. Physical load was measured using electromyography, while mental load was analyzed by measuring the heart rate variation (HRV). After each simulation, cylindrical grip strength was evaluated using a Jamar dynamometer, and the Surgery Task Load Index (SURG-TLX) questionnaire was applied.Results: Differences in muscle activation were observed, with greater activation in the LT-Prone position, where the erector spinae reached 27.7%. This was reflected in increased mental, physical, and temporal demands. Similarly, overactivation of the wrist extensor, averaging 229%, was related to back muscle fatigue, when compared to low activation (10%). No significant differences were found in grip strength, while a greater HRV was observed with LT in both positions.Conclusion: We observed differences in physical and mental fatigue related to patient position, the lithotripter used and the surgeon's muscle activation. This pilot study gives insights into conditions that should be considered to enhance urologist performance and prevent injuries during PCNL.","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"43 1","pages":"545"},"PeriodicalIF":2.9,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145024227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Management of renal cancer with inferior vena cava extension over 30 years: a bi-centric study. 下腔静脉延伸超过30年的肾癌的处理：一项双中心研究。

IF 2.9 2区医学

World Journal of Urology Pub Date : 2025-09-09 DOI: 10.1007/s00345-025-05914-9

Thomas Poirier, Benoit Mesnard, Mathieu Roumiguie, Stephane De Vergie, Cloe Geay, Julien Branchereau, Thomas Prudhomme, Jerome Rigaud

{"title":"Management of renal cancer with inferior vena cava extension over 30 years: a bi-centric study.","authors":"Thomas Poirier, Benoit Mesnard, Mathieu Roumiguie, Stephane De Vergie, Cloe Geay, Julien Branchereau, Thomas Prudhomme, Jerome Rigaud","doi":"10.1007/s00345-025-05914-9","DOIUrl":"10.1007/s00345-025-05914-9","url":null,"abstract":"Purpose: In 5-10% of cases, renal cancer extends into the venous system, particularly the inferior vena cava (IVC), which worsens prognosis. This study aims to assess morbidity, mortality, and oncological outcomes of patients treated surgically for renal cancer with IVC extension over a 30-year period, in two experienced centers.Materials and methods: This bicentric, retrospective study analyzed patients treated between 1988 and 2020 for renal cancer involving the IVC. Surgical approach varied based on thrombus level, with CPB mostly employed for thrombi above the hepatic veins.Results: From 1988 to 2020, 213 patients were treated. Thrombi below the hepatic veins were found in 137 patients (64.3%), while 76 (35.7%) had thrombi above the hepatic veins. Synchronous metastases were identified in 34.3%. Median blood loss was 1.75 L. Transfusions were required in 81.8%.CPB use significantly extended hospital stay (p < 0.001) and increased complication rates (p < 0.01). Morbidity was recorded in 53% of patients. Postoperative mortality within 30 days occurred in 9.4% of cases. Median follow-up was 25 months. The 2- and 5-year OS rates were 50.2% and 29.6%, respectively. In multivariate analysis, M + and pN + status at diagnosis were the primaries prognostics factors for OS (HR = 1.54, p = 0.033 and HR = 2.21, p = 0.002). The 2 and 5 years PFS were 25.3% and 11.7%, respectively.Conclusion: Renal cancer with IVC extension remains a highly aggressive disease with poor prognosis. While surgery offers a potential cure for some patients, the high rates of perioperative morbidity and mortality remain a challenge.","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"43 1","pages":"544"},"PeriodicalIF":2.9,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145024310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development and validation of a non-invasive nomogram for predicting proximal ureteral impacted calculi. 一种预测输尿管近端冲击型结石的无创影像的发展和验证。

IF 2.9 2区医学

World Journal of Urology Pub Date : 2025-09-09 DOI: 10.1007/s00345-025-05909-6

Quanfang He, Peichang Wang, Huaxu Yang, Hua Tang, Lixiang Lan, Shaoting Chen

{"title":"Development and validation of a non-invasive nomogram for predicting proximal ureteral impacted calculi.","authors":"Quanfang He, Peichang Wang, Huaxu Yang, Hua Tang, Lixiang Lan, Shaoting Chen","doi":"10.1007/s00345-025-05909-6","DOIUrl":"10.1007/s00345-025-05909-6","url":null,"abstract":"Objective: To develop and validate a prognostic nomogram for predicting the risk of proximal ureteral impacted calculi, supporting personalized clinical management.Methods: This retrospective, multicenter study employed a continuous cohort of 391 patients with proximal ureteral stones treated between January 2021 and April 2024. Data from Longyan People's Hospital (affiliated with Xiamen Medical College) comprised the training set, while independent external validation was performed using data from The Fifth Affiliated Hospital of Fujian University of Traditional Chinese Medicine. Independent predictors were ascertained via univariate and multivariate logistic regression analysis. A nomogram was subsequently developed, and its predictive performance and clinical utility were evaluated.Results: Hydronephrosis (OR = 3.911, 95% CI: 1.152-13.227, P = 0.044), maximum ureteral wall thickness (UWT) (OR = 9.574, 95% CI: 5.775-15.874, P < 0.001), maximum ureteral jet velocity (Vmax) (OR = 0.762, 95% CI: 0.677-0.858, P < 0.001), stone Hounsfield units (HU) (OR = 2.228, 95% CI: 1.207-4.114, P = 0.002), and stone size (OR = 2.069, 95% CI: 1.128-3.796, P = 0.019) emerged as significant independent predictors of impacted proximal ureteral calculi. The nomogram exhibited high predictive accuracy, with area under the receiver operating characteristic curve (AUC) values of 0.928 (training set) and 0.903 (validation set). Decision curve analysis indicated substantial net clinical benefit across a range of threshold probabilities for clinical use.Conclusion: Hydronephrosis, UWT, Vmax, stone HU, and stone size constitute independent predictors of proximal ureteral impacted calculi. The nomogram incorporating these factors provides a reliable prognostic tool to assist in treatment planning and potentially enhance patient outcomes in clinical practice.","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"43 1","pages":"547"},"PeriodicalIF":2.9,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145024251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The multidrug resistance protein inhibitor, MK571 inhibits the hypercontractility state in prostate from obese mice. 多药耐药蛋白抑制剂MK571抑制肥胖小鼠前列腺的过度收缩状态。

IF 2.9 2区医学

World Journal of Urology Pub Date : 2025-09-09 DOI: 10.1007/s00345-025-05929-2

Gabriela Reolon Passos, Natalícia de Jesus Antunes, Mariana G de Oliveira, José Luiz da Costa, André Almeida Schenka, Adriano Fregonesi, Edson Antunes, Fabiola Zakia Mónica

{"title":"The multidrug resistance protein inhibitor, MK571 inhibits the hypercontractility state in prostate from obese mice.","authors":"Gabriela Reolon Passos, Natalícia de Jesus Antunes, Mariana G de Oliveira, José Luiz da Costa, André Almeida Schenka, Adriano Fregonesi, Edson Antunes, Fabiola Zakia Mónica","doi":"10.1007/s00345-025-05929-2","DOIUrl":"https://doi.org/10.1007/s00345-025-05929-2","url":null,"abstract":"Purpose: To evaluate the impact of MRP inhibition by MK571 on prostate hypercontractility in diet-induced obesity, based on the hypothesis that this intervention enhances intracellular cAMP and cGMP signaling.Methods: Adult C57BL/6 mice were divided into three groups: (i) lean, (ii) obese, and (iii) obese + MK571 (5 mg/kg/day, 14 days). The prostate was isolated for immunohistochemistry, biochemistry and functional assays. Electrical field stimulation (EFS) and concentration-response curves to the α1-adrenoceptor agonist phenylephrine or the nitric oxide donor sodium nitroprusside were performed with or without MK571 (20 µM, 30 min), guanylyl or adenylyl cyclase inhibitors (ODQ and SQ22,536, respectively), or the leukotriene receptor antagonist montelukast.Results: MRP4 and MRP5 were detected in the prostate. In vitro, phenylephrine-and EFS-induced contractions were significantly higher in prostates from obese mice compared to lean mice. Adding MK571 to the myograph chamber significantly reduced the contractile responses and improved relaxation in obese mice, reaching similar responses to those of the lean group. These effects of MK571 were inhibited by co-incubation with ODQ and SQ22536, but not by montelukast. Additionally, treating obese mice for 14 days reversed prostate hypercontractility. Obese mice exhibited significantly lower intracellular levels of cGMP compared to lean, while cAMP levels were similar. However, MK571 treatment significantly increased both cyclic nucleotides, restoring cGMP levels close to those in lean mice.Conclusion: Our findings highlight that inhibiting MRPs promotes the accumulation of cGMP in the prostate, ultimately enhancing smooth muscle relaxation.","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"43 1","pages":"546"},"PeriodicalIF":2.9,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145024221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Open access publishing: is urology ready? A survey of authors, readers, and editorial board's knowledge, impressions and satisfaction. 开放获取出版：泌尿外科准备好了吗？对作者、读者和编委会的知识、印象和满意度的调查。

IF 2.9 2区医学

World Journal of Urology Pub Date : 2025-09-08 DOI: 10.1007/s00345-025-05928-3

Abbas Guennoun, Kahina Bensaadi, Marc-André Simard, Liam Murad, Ryan Schwartz, Kelven Chen, Saud Almousa, Max Levitt, Michael Leveridge, Robert Siemens, Vincent Larivière, Naeem Bhojani

{"title":"Open access publishing: is urology ready? A survey of authors, readers, and editorial board's knowledge, impressions and satisfaction.","authors":"Abbas Guennoun, Kahina Bensaadi, Marc-André Simard, Liam Murad, Ryan Schwartz, Kelven Chen, Saud Almousa, Max Levitt, Michael Leveridge, Robert Siemens, Vincent Larivière, Naeem Bhojani","doi":"10.1007/s00345-025-05928-3","DOIUrl":"https://doi.org/10.1007/s00345-025-05928-3","url":null,"abstract":"Purpose: To report the level of knowledge, impressions, and satisfaction of Urology readers, authors, and editorial boards regarding Open Access (OA) publishing in the field of Urology and to determine their satisfaction with the current OA models.Methods: We developed an online, five-section cross-sectional survey including 23 questions. To recruit participants, we used mixed methods to obtain responses based on a simple random sampling and convenience sampling. Herein we present descriptive outcomes of the responses.Results: 157 participants from 21 countries responded to the survey between May 2023 and October 2024. The majority of respondents (80.2%) reported having \"Acceptable\" to \"Excellent\" knowledge regarding OA publishing. However, of those that responded they were familiar with the concepts, only a minority knew the definitions of Gold, Green, Diamond, and Hybrid OA publishing models. Of all respondents, 49.7% reported having a \"Positive\" to \"Strongly positive\" impressions toward OA publishing, whereas 16.6% had \"Negative\" to \"Strongly negative\" impressions. Although a majority agreed that OA publishing can offer several advantages, 40.8% thought that the quality of peer-review is lower for OA journals compared to traditional publishing models. The vast majority (82.2%) agreed that articles processing charge (APC) can be overly burdensome for authors. Members of a Urology journal editorial board are more incline to not publish in an OA journal.Conclusion: Results from this anonymous, international survey among urologists, show high awareness of OA publishing with low knowledge regarding details. Participants are pessimistic regarding the quality of OA journals and peer-review.","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"43 1","pages":"542"},"PeriodicalIF":2.9,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145024254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Percutaneous nephrolithotomy under total X-ray free technique in horseshoe kidney stones: a 10-year experience from a large stone center. 全无x线技术下经皮肾镜取石术治疗马蹄形肾结石：一个大型结石中心的10年经验。

IF 2.9 2区医学

World Journal of Urology Pub Date : 2025-09-05 DOI: 10.1007/s00345-025-05908-7

Bo Xiao, Yang Chen, Sen Lin, Xue Zeng, Nan Zhang, Zhongjie Shan, Wenjie Bai, Tianfu Ding, Jianxing Li

{"title":"Percutaneous nephrolithotomy under total X-ray free technique in horseshoe kidney stones: a 10-year experience from a large stone center.","authors":"Bo Xiao, Yang Chen, Sen Lin, Xue Zeng, Nan Zhang, Zhongjie Shan, Wenjie Bai, Tianfu Ding, Jianxing Li","doi":"10.1007/s00345-025-05908-7","DOIUrl":"https://doi.org/10.1007/s00345-025-05908-7","url":null,"abstract":"Objectives: To report outcomes of complete ultrasound-guided percutaneous nephrolithotomy (PCNL) for horseshoe kidney (HSK) stones at a high-volume center and evaluate a novel technique (Needle-perc-assisted endoscopic surgery, NAES) for these patients.Patients and methods: We retrospectively reviewed all HSK stone patients who underwent PCNL at our institution over a 10-year period. The NAES technique was utilized during the most recent 4 years. Preoperative, intraoperative, and postoperative characteristics were analyzed, comparing traditional PCNL with NAES.Results: Successful renal access was achieved in all 82 procedures. One-stage surgery was performed in 62 renal units (75.6%), while 20 (24.4%) required second-stage surgery. The final stone-free rate (SFR) was 74.4% (61/82). The prone position was predominantly used (96.3%), and the upper calyx was the initial target in 87.8% (72/82) of renal units. Residual stones were most frequently located in the isthmus (76.2%, 16/21) and lower calyx (23.8%, 5/21). Patients were stratified into NAES (n = 35) and conventional PCNL (n = 47) groups. The NAES group demonstrated significantly higher SFR (85.7% vs. 68.1%, p = 0.025), improved pain scores on postoperative day 1 (POD1), and shorter hospital stays.Conclusion: Complete ultrasound-guided PCNL is safe and effective for HSK stones. The NAES technique significantly enhances stone clearance rates and improves patient outcomes in this cohort.","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"43 1","pages":"540"},"PeriodicalIF":2.9,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145006607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Should percutaneous nephrolithotomy be performed in patients with severe chronic kidney disease? A closer look at renal function outcomes. 严重慢性肾病患者是否应行经皮肾镜取石术？仔细观察肾功能结果。

IF 2.9 2区医学

World Journal of Urology Pub Date : 2025-09-03 DOI: 10.1007/s00345-025-05906-9

Vinay Durbhakula, Ziv Savin, Eve Frangopoulos, Asher Mandel, Linda Dayan Rahmani, Adam Daniel Geffner, Esther Kim, Aubrey Dibello, Blair Gallante, William M Atallah, Mantu Gupta

引用次数: 0