World Journal of Urology最新文献

{"title":"Diagnostic performance and pathologic associations of the UroVysion assay in patients with upper tract lesions and negative urinary cytology: a large-scale real-world study of 1,256 patients.","authors":"Longtao Zheng, Bao Guan, Zheng Wu, Yi Ding, Bei Zhang, Xuesong Li, Yanqing Gong","doi":"10.1007/s00345-026-06876-2","DOIUrl":"10.1007/s00345-026-06876-2","url":null,"abstract":"<p><strong>Purpose: </strong>The UroVysion assay is widely used for diagnosing upper tract urothelial carcinoma (UTUC), but its value in patients with negative urinary cytology remains unclear. This study evaluated its diagnostic performance and pathological associations in this specific population.</p><p><strong>Methods: </strong>This retrospective study included 1,256 patients with upper tract lesions on imaging, negative urinary cytology, and preoperative UroVysion testing. Pathological diagnosis served as the reference standard. Diagnostic performance was assessed using sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy. Logistic regression analysis was used to evaluate the association between UroVysion positivity and high-grade disease, lymphovascular invasion (LVI), and muscle invasion (≥ pT2). Subgroup analyses were performed according to tumor size and location.</p><p><strong>Results: </strong>Among the 1,256 patients, 1,007 (80.2%) had UTUC and 249 (19.8%) had benign lesions. The UroVysion assay showed a sensitivity of 66.9%, specificity of 82.7%, PPV of 94.0%, and NPV of 38.2%, and an overall accuracy of 70.1% for UTUC diagnosis. UroVysion positivity was independently associated with high-grade disease (OR = 2.10, p < 0.001), LVI (OR = 1.63, p = 0.023), and muscle invasion (OR = 1.32, p = 0.049). Interaction tests showed no significant heterogeneity by tumor size or tumor location.</p><p><strong>Conclusion: </strong>In patients with upper tract lesions and negative cytology, the UroVysion assay provides complementary diagnostic information and is associated with adverse pathological features. No significant heterogeneity in these associations was observed according to tumor size or location.</p>","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"44 1","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149220903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mini-PCNL and mini-ECIRS in a solitary kidney population: a single-center experience.","authors":"Francesco Di Bello, Alejandra Bravo-Balado, Paolo Verri, Paula Izquierdo, Roger Pujol, Lucio Fila, Andres K Kanashiro, Oriol Angerri","doi":"10.1007/s00345-026-06874-4","DOIUrl":"https://doi.org/10.1007/s00345-026-06874-4","url":null,"abstract":"<p><strong>Objective: </strong>To quantify the postoperative outcomes, namely complication rates and renal function, of mini-combined endoscopic combined intrarenal surgery (ECIRS) or mini-percutaneous nephrolithotomy (PCNL) within solitary kidney (SK) patients.</p><p><strong>Methods: </strong>We relied on a single-centre retrospective database including 658 patients who underwent endourological surgeries for stone treatment, between 2018 and 2025. Endpoints, namely intraoperative and postoperative complications, length of stay (LOS), and renal function were quantified.</p><p><strong>Results: </strong>Based on a median follow-up of 15 months (IQR 6-35), 28 SK patients, for a total of 33 surgeries, were included. Out of 33 surgeries, 18 (55%) consisted of ECIRS and 15 (45%) were PCNL. The rates of SK patients who underwent surgeries ranged from 3% in 2018 to 14% in 2025. Out of all 33 surgeries, 14 (42%) were performed in Guy's stone score (GSS) ≥ III stones. Median volume of treated stones was 120 mm3 (IQR 12-305). Among 33 surgeries, five (15%) were associated with intraoperative complications and 12 (36%) were associated with postoperative complications (Clavien-Dindo IIIa, n = 1, 3%). Residual stones were present in 12 (36%) surgeries. According to renal function, no differences were recorded between pre-operative and either 3-mo eGFR (p = 0.2) or 6-mo eGFR (p = 0.2).</p><p><strong>Conclusions: </strong>In this single-center European cohort, mini-ECIRS and mini-PCNL were feasible and safe treatment options for stones in SK patients, with acceptable postoperative outcomes. Nevertheless, larger prospective studies are needed to strengthen the current evidence.</p>","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"44 1","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149216822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microvascular architecture of the prostatic urethra: anatomical basis for extended urethral preservation in robot-assisted radical prostatectomy.","authors":"Anastasios D Asimakopoulos, Gaia Colalillo, Filippo Annino, Aurora Polvani, Sacchini Alessio, Andrea Fuschi, Thierry Piechaud, Richard Gaston, Filippo Borri","doi":"10.1007/s00345-026-06869-1","DOIUrl":"https://doi.org/10.1007/s00345-026-06869-1","url":null,"abstract":"<p><strong>Purpose: </strong>To characterize the microvascular architecture of the prostatic urethra (PU) and assess its potential anatomical relevance to extended prostatic urethral preservation (EPUP) during robot-assisted radical prostatectomy.</p><p><strong>Methods: </strong>This pilot morphological study included three non-distorted prostate specimens obtained from cystoprostatectomy. Specimens were entirely submitted for histological examination and evaluated using hematoxylin and eosin and modified Verhoeff-Masson staining. Periurethral vascular structures were morphologically characterized, and their distance from the urothelial basement membrane was measured on digital whole-slide images.</p><p><strong>Results: </strong>Two morphologically distinct periurethral vascular compartments were identified. The Inner Periurethral Capillary Network (IPCN) consisted of small-caliber vascular structures within the subepithelial connective tissue (SCT/chorion), whereas the Outer Vascular Network (OVN) comprised predominantly larger vessels with more conspicuous muscular walls. The distance between the urothelial basement membrane and the IPCN ranged from 0.10 to 0.94 mm. However, the present study does not demonstrate arterial connectivity, independent perfusion, or a causal relationship between IPCN preservation and functional outcomes.</p><p><strong>Conclusion: </strong>A distinct inner periurethral vascular compartment was identified within the SCT of the PU. Its anatomical location may provide a potential substrate for preservation of the local vascular environment during EPUP. Larger anatomical studies incorporating immunohistochemical and intraoperative perfusion assessment of the preserved urethra in cases of EPUP are warranted.</p>","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"44 1","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149207999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Confidence without consensus? Human versus AI abstracts in urology.","authors":"Sholem Hack, Shlomo Resnik, Yoram Dekel, Shlomi Moshe, Daniel Noy, Mohammad Shalabi, Ari Frajewicki, Omri Zonenfeld, Sobhi Khoury, Israel Benzekry, Yazeed Barghouthy, Maharan Kabha","doi":"10.1007/s00345-026-06872-6","DOIUrl":"10.1007/s00345-026-06872-6","url":null,"abstract":"<p><strong>Objective: </strong>This study asked whether urologists can tell human-written abstracts apart from artificial intelligence (AI)-written abstracts when both describe the same study, and whether the answer depends on which AI model did the writing.</p><p><strong>Methods: </strong>Fifteen published urology studies were selected. For each study, the original human-written abstract was paired with three AI-written abstracts covering the same material, produced by Claude Sonnet 4.6, GPT-5.5, and Gemini 3 Flash using identical instructions and each model's ordinary consumer settings. Because all four versions described the same study, the underlying data were held constant, and the versions differed in how that material was written and presented. The resulting 60 abstracts were stripped of identifying information, and eight urologists read all of them without knowing which was which (480 judgments in total). For each abstract, reviewers stated whether they believed it was written by a human or by AI, rated how confident they were in that judgment, and rated the abstract's quality and credibility on 5-point scales.</p><p><strong>Results: </strong>Reviewers correctly identified AI-written abstracts 49.3% of the time, approximately 50%, compared with 62.4% for human-written abstracts (p = .011). Results depended heavily on which model wrote the text (p = .003). Abstracts written by Claude were recognized as AI only 40.0% of the time, significantly less often than human abstracts were correctly identified (p = .003) and less often than GPT abstracts (56.8%, p = .038); Gemini fell between the two at 50.9%. Quality ratings differed only for GPT, which scored lower than human abstracts (p = .046; omnibus p = .030); credibility ratings did not differ between sources at all (p = .577). Reviewers who felt confident were no more likely to be correct (p = .749), and reviewers seldom agreed with one another about which abstracts were AI-written (Fleiss' κ = -0.009).</p><p><strong>Conclusion: </strong>Urologists could not reliably recognize AI-written urology abstracts, and the difficulty came mainly from one model rather than from AI writing in general. How good an abstract appeared had little to do with whether its authorship was correctly identified, and neither reviewer confidence nor agreement between reviewers gave any warning. Reading alone is therefore not a dependable way to detect undisclosed AI authorship.</p>","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"44 1","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13675285/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149207925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of accuracy, quality, and readability of large language models in kidney transplantation practice.","authors":"Muhammed Emin Polat, Mecit Celik, Kazim Ceviz, Mustafa Karaaslan, Yusuf Kasap, Caglar Sarioglu, Sedat Tastemur, Hakan Bahadir Haberal, Alessio Pecoraro, Thomas Prudhomme, Alicia L Abad, Alberto Piana, Muhammet Irfan Donmez, Erkan Olcucuoglu, Angelo Territo","doi":"10.1007/s00345-026-06856-6","DOIUrl":"https://doi.org/10.1007/s00345-026-06856-6","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to comparatively evaluate the accuracy, overall quality, and readability of responses generated by three contemporary large language models (LLMs)-Grok AI, ChatGPT-5 Plus, and Gemini 2.5 Flash-to clinical questions commonly encountered in kidney transplantation (KT) practice.</p><p><strong>Methods: </strong>Ten open-ended clinical scenarios covering surgical techniques, complication management, immunosuppressive strategies, and perioperative care were independently assessed by two experienced physicians. LLM-generated responses were evaluated using a structured rubric assessing scientific accuracy, comprehensiveness, clarity, and clinical relevance (equally weighted), along with the Global Quality Score (GQS). Readability was analyzed using the Flesch Reading Ease Score (FRES). Inter-rater reliability was determined using Cronbach's alpha and intraclass correlation coefficients (ICC).</p><p><strong>Results: </strong>All three LLMs demonstrated consistently high performance, with mean rubric scores exceeding 9.2/10 and GQS values above 4.4/5. Grok AI achieved the highest numerical scores (rubric: 9.5 ± 0.71; GQS: 4.7 ± 0.48), followed by ChatGPT-5 Plus (9.4 ± 0.70; 4.6 ± 0.52) and Gemini 2.5 Flash (9.2 ± 1.03; 4.4 ± 0.70); however, no statistically significant differences were observed (p > 0.05). FRES values ranged from 23.85 to 32.19, indicating professional-level readability suitable for physicians. Inter-rater reliability was high across all measures (Cronbach's alpha: 0.737-0.889; ICC: p < 0.05). Key limitations include the potential for LLM hallucinations, the limited number of scenarios, and the evaluation of text-based responses at a single time point.</p><p><strong>Conclusions: </strong>Current-generation LLMs show high and comparable performance in addressing complex KT-related clinical questions. Their consistent accuracy, quality, and readability support their potential role as adjunctive clinical decision-support tools, provided appropriate physician oversight.</p>","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"44 1","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149207982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EQUIPOISE: EQUivalence In Prostate cancer treatment: surgery Or radiotherapy? An Intention-to-treat Survival analysis from real-world Evidence.","authors":"Gustavo A Viani, Ana Carolina Hamamura, Caio Viani Arruda, Carlos E Cardoso, Helio A Salmon, Gustavo O Amaral","doi":"10.1007/s00345-026-06811-5","DOIUrl":"10.1007/s00345-026-06811-5","url":null,"abstract":"<p><strong>Purpose: </strong>To compare cancer-specific and overall survival between a surgery-based strategy and radiotherapy plus androgen deprivation (RT + ADT) in intermediate- and high-risk localized prostate cancer, using contemporary real-world data from a Latin American public health system.</p><p><strong>Methods: </strong>Using the state-wide cancer registry of São Paulo, Brazil, we studied men with intermediate- or high-risk localized prostate cancer diagnosed in 2014-2023. Treatment was assigned by initial modality (intention-to-treat). The primary outcome was cancer-specific survival (CSS), with overall survival (OS) secondary. Groups were compared after 1:1 propensity-score matching, with weighting and per-protocol sensitivity analyses.</p><p><strong>Results: </strong>Of 21,292 patients, matching yielded 4263 pairs (all standardized mean differences below 0.10). CSS did not differ between RT + ADT and surgery [hazard ratio 0.87, 95% CI 0.58-1.29, p = 0.48 (intermediate); 1.00, 95% CI 0.78-1.27, p = 0.98 (high)]. At 5 years, CSS with surgery versus RT + ADT was 98.0% versus 96.6% (intermediate) and 94.9% versus 92.9% (high); OS was 92.6% versus 84.6% and 87.5% versus 82.7%. The crude OS advantage of surgery did not persist after matching (p = 0.10; p = 0.33). Additional therapy was given to 20.2% of operated men, rising to 48.9% in pN1 disease.</p><p><strong>Conclusions: </strong>Surgery and RT + ADT showed similar cancer-specific and overall survival after adjustment, and surgery frequently entailed multimodal therapy. Both can be presented as alternative therapeutic options in shared decision-making.</p>","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"44 1","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13672427/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149196789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ambient artificial intelligence scribes in urology: a pilot evaluation of user experience and clinical efficiency gains.","authors":"Aleksandra M Golos, Sharath Reddy, Mursal Gardezi, Thomas V Martin, Marianne Casilla-Lennon","doi":"10.1007/s00345-026-06860-w","DOIUrl":"10.1007/s00345-026-06860-w","url":null,"abstract":"<p><strong>Purpose: </strong>Ambient artificial intelligence (AI) scribes aim to reduce documentation burden, yet evidence in urology is limited. We evaluated the pilot rollout of an AI scribe system in our academic urology department, focusing on user experience and electronic health record-based efficiency metrics.</p><p><strong>Methods: </strong>AI scribes were introduced into outpatient urology clinics in June 2024. We developed a user experience questionnaire to assess navigation, functionality, workload reduction, and clinical impact at 1 and 11 months of implementation. Clinical efficiency was evaluated using changes in Epic Signal metrics from pre- to post-rollout. Descriptive statistics were stratified by AI scribe adoption status and documentation method.</p><p><strong>Results: </strong>Of 41 eligible clinicians, seven initially enrolled in the AI scribe pilot. Two clinicians discontinued use, and three additional clinicians adopted the technology, resulting in eight persistent AI scribe users (19.5%). Median utilization in office visit notes was 90%. User experience improved across all domains, most notably in workload reduction (3.1 to 4.7). Users reported reduced after-hours charting and improved patient interaction; limitations included lack of pre-charting capabilities and insufficient adaptation to urology-specific documentation needs. AI scribe users demonstrated consistent within-clinician reductions in time in notes per day (-28.7%; 14.0 min), time in notes per appointment (-21.9%; 0.9 min), and time outside scheduled hours (-28.6%; 13.4 min). Inconsistent background trends were observed among non-users.</p><p><strong>Conclusion: </strong>AI scribe users reported positive experience with the technology and demonstrated reductions in documentation burden. Findings are exploratory and support larger, controlled evaluations of note quality and workflow impact.</p>","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"44 1","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149184685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety and complications of upper pole puncture in supine percutaneous nephrolithotomy.","authors":"Juliana Villanueva-Congote, Yi W Li, Michal Segall, Mehmet Gokce, Silvia Proietti, Guido Giusti, Jose Ernesto Torres Garcia, Braulio Manzo, Alan Yaghoubian, Mariano Gonzalez, Leye Ajayi, Daniel A Wollin, Brian H Eisner","doi":"10.1007/s00345-026-06735-0","DOIUrl":"10.1007/s00345-026-06735-0","url":null,"abstract":"<p><strong>Objective: </strong>Supine percutaneous nephrolithotomy (PCNL) has gained attention as a viable alternative to the traditional/historical prone approach for the treatment of large renal stones. However, concerns remain regarding the safety and feasibility of upper calyx punctures in the supine position, particularly for upper-pole access. This multicenter, retrospective cohort study evaluated the safety and stone-free rates of upper-pole punctures in supine PCNL, comparing outcomes with middle and lower calyx punctures and with literature on prone PCNL.</p><p><strong>Methods: </strong>This retrospective study analyzed supine PCNL cases performed between 2009 and 2019 across eight international centers, categorizing patients by calyx of entry (upper, middle, or lower). Patients who required multiple calyx entries were excluded. Demographics, surgical details, and outcomes were recorded, including complications and stone-free rates. We used logistic regression to assess the association between stone-free rates and calyx puncture sites, adjusting for age, gender, Guy's Stone Score, and ASA score. Based on the initial findings, we performed a second multivariable logistic regression among patients undergoing upper calyx puncture using the same covariates. ANOVA was used to compare the means of quantitative variables, and Chi-square tests assessed associations between categorical variables. Bonferroni adjustment was applied when appropriate.</p><p><strong>Results: </strong>Among 989 patients, 10% had upper, 28.5% middle, and 61.5% lower calyx punctures. No significant differences were found in overall complication rates when comparing upper, middle, and lower calyces. Thoracic complications were rare and did not differ significantly across calyces (p = 0.74). Upper calyx punctures had lower stone-free rates (51%) compared to middle (77.7%) and lower (62.8%) punctures (p < 0.001). The overall complication rate did not differ significantly (p = 0.82). According to the logistic regression, patients with a middle puncture site had 2.98 times higher odds of a stone-free outcome than those with an upper puncture site (OR, 2.98; 95% CI, 1.69-5.29). In contrast, patients with a lower puncture site did not have a significant difference in stone-free rates compared to those with an upper puncture (OR = 1.10, 95% CI: 0.64, 1.86, p = 0.7). Among patients undergoing upper calyx puncture, Guy's Stone Score 4 was independently associated with lower odds of achieving stone-free status (OR 0.20, 95% CI 0.04-0.91; p = 0.045). No significant associations were observed for age, gender, or ASA classification.</p><p><strong>Conclusion: </strong>Upper calyx punctures showed similar complication rates to middle and lower calyx punctures, with slightly lower stone-free rates likely due to higher stone complexity. These findings support the feasibility, safety, and efficacy of supine PCNL for upper calyx access.</p>","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"44 1","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13668940/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149184779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor: Analysis populations and extraction consistency in combined prostate and bladder stone surgery.","authors":"Asad Ur Rab","doi":"10.1007/s00345-026-06847-7","DOIUrl":"10.1007/s00345-026-06847-7","url":null,"abstract":"","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"44 1","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149184764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between sarcopenia, lower urinary tract symptoms, and urinary incontinence-related anxiety in community-dwelling older women: a cross-sectional study.","authors":"Yukari Aishita, Hyuma Makizako, Daijo Shiratsuchi, Shoma Akaida, Yuto Kiuchi, Mana Tateishi, Ryoji Kiyama, Takuro Kubozono, Toshihiro Takenaka, Mitsuru Ohishi","doi":"10.1007/s00345-026-06864-6","DOIUrl":"10.1007/s00345-026-06864-6","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to examine the associations among sarcopenia, lower urinary tract symptoms, and anxiety in urinary incontinence in community-dwelling older women.</p><p><strong>Methods: </strong>We analyzed data from 194 older women (mean age: 74.7 ± 5.8 years) who participated in a community cohort study. Sarcopenia was defined according to the Asian Working Group for Sarcopenia 2019 criteria. Lower urinary tract symptoms were classified into two groups based on the presence or absence of urinary incontinence, increased daytime frequency, and nocturia. Anxiety was classified into two groups based on the presence or absence of urinary incontinence-related anxiety in urinary incontinence. Associations among sarcopenia, lower urinary tract symptoms, and anxiety in urinary incontinence were examined using binary logistic regression analysis.</p><p><strong>Results: </strong>Of the participants, 31 (16%) were classified as having sarcopenia, of whom 67.7% had nocturia, which was a significantly higher proportion (42.9%) than that in those without sarcopenia (p = 0.011). Multivariate analysis revealed that sarcopenia was significantly associated with nocturia (odds ratio: 2.61; 95% confidence interval: 1.05-6.49). No association was observed between sarcopenia and urinary incontinence, increased daytime frequency, or anxiety in urinary incontinence.</p><p><strong>Conclusions: </strong>Sarcopenia was independently associated with nocturia in community-dwelling older women, regardless of the presence or absence of concomitant lower urinary tract symptoms. These findings suggest that sarcopenia is related to nocturia and highlight the potential importance of evaluating sarcopenia in addition to pelvic floor muscles in older women.</p>","PeriodicalId":23954,"journal":{"name":"World Journal of Urology","volume":"44 1","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13661739/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149184717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}