Wiener medizinische Wochenschrift最新文献

{"title":"Diabetic retinopathy-recommendations for screening and treatment.","authors":"Alisa Pedrini, Yvonne Nowosielski, Matus Rehak","doi":"10.1007/s10354-025-01088-6","DOIUrl":"10.1007/s10354-025-01088-6","url":null,"abstract":"<p><p>Diabetic retinopathy (DR), the prevalence of which continues to rise, is one of the most common causes of vision loss worldwide. Experimental and clinical research in recent years has contributed to a better understanding of the pathogenesis of DR, which is complex and results from many interrelated processes leading to abnormal permeability and occlusion of the retinal vasculature, with ischemia and subsequent neovascularization. According to the absence or presence of neovascularization, DR is divided into two main forms: nonproliferative and proliferative DR. From nonproliferative to proliferative disease, diabetic macular edema (DME) can develop anywhere along the spectrum. As the majority of diabetics have no ophthalmologic symptoms, screening plays an important role in preventing the development of retinal disease. Specific treatment options beyond metabolic risk factor control, including intravitreal administration of anti-vascular endothelial growth factor (VEGF) agents or corticosteroids, laser photocoagulation, and vitreous surgery, are effective approaches for ocular diabetic complications.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":" ","pages":"253-263"},"PeriodicalIF":1.1,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144043204","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current trends in ophthalmology with an impact on medicine and society.","authors":"Sebastian M Waldstein","doi":"10.1007/s10354-025-01087-7","DOIUrl":"https://doi.org/10.1007/s10354-025-01087-7","url":null,"abstract":"","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":"175 7-8","pages":"141-142"},"PeriodicalIF":1.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144030543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial intelligence in managing retinal disease-current concepts and relevant aspects for health care providers.","authors":"Sophie Riedl, Klaudia Birner, Ursula Schmidt-Erfurth","doi":"10.1007/s10354-024-01069-1","DOIUrl":"10.1007/s10354-024-01069-1","url":null,"abstract":"<p><p>Given how the diagnosis and management of many ocular and, most specifically, retinal diseases heavily rely on various imaging modalities, the introduction of artificial intelligence (AI) into this field has been a logical, inevitable, and successful development in recent decades. The field of retinal diseases has practically become a showcase for the use of AI in medicine. In this article, after providing a short overview of the most relevant retinal diseases and their socioeconomic impact, we highlight various aspects of how AI can be applied in research, diagnosis, and disease management and how this is expected to alter patient flows, affecting also health care professionals beyond ophthalmologists.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":" ","pages":"143-152"},"PeriodicalIF":1.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12031981/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sustainable practices in ophthalmology-steps towards environmental stewardship in healthcare.","authors":"Nicolas Winklmair, David F Chang, Oliver Findl","doi":"10.1007/s10354-024-01063-7","DOIUrl":"10.1007/s10354-024-01063-7","url":null,"abstract":"<p><p>The healthcare sector, responsible for approximately 4-5% of global carbon dioxide equivalent (CO₂eq) emissions, significantly impacts the environment due to its high energy consumption and waste generation. As a specialty, ophthalmology has a disproportionately large environmental impact because of the high annual volume of ophthalmic surgeries. In recent years, significant organized efforts have focused on reducing ophthalmology's carbon footprint while maintaining quality patient care. As one example, EyeSustain is a coalition of 50 global ophthalmology societies collaborating to advance sustainability in the delivery of eye care through education, research, and advocacy. Education and advocacy are critical to raising awareness and promoting the implementation of sustainable practices among physicians. Many of these practices can and should be applied throughout the broader healthcare system, and EyeSustain is a model of how other specialties can organize education and advocacy efforts through medical societies. We review current initiatives, advocacy efforts, and waste-reduction strategies aimed at reducing the environmental footprint of ophthalmic procedures.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":" ","pages":"203-209"},"PeriodicalIF":1.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142628937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A review of rhegmatogenous retinal detachment: past, present and future.","authors":"Jessica Xiong, Tuan Tran, Sebastian M Waldstein, Adrian T Fung","doi":"10.1007/s10354-025-01085-9","DOIUrl":"10.1007/s10354-025-01085-9","url":null,"abstract":"<p><p>Retinal detachments are ophthalmic emergencies given their potential to become a permanently blinding disorder if left untreated. This review will outline the history, pathogenesis, clinical presentation, and current and future management of retinal detachments.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":" ","pages":"186-202"},"PeriodicalIF":1.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12031774/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intravitreal therapy-success stories and challenges.","authors":"Daniel Egger, Katharina A Heger, Matthias Bolz, Max P Brinkmann, Katharina Krepler, Pia Veronika Vecsei-Marlovits, Andreas Wedrich, Sebastian M Waldstein","doi":"10.1007/s10354-024-01070-8","DOIUrl":"10.1007/s10354-024-01070-8","url":null,"abstract":"<p><p>Intravitreal injections have revolutionized the treatment of various sight-threatening diseases of the posterior segment of the eye. Initially explored for treatment of bacterial endophthalmitis, intravitreal injections rapidly expanded to combat retinal vascular disease in particular. Especially anti-vascular endothelial growth factor agents have emerged as a cornerstone of intravitreal therapy, targeting neovascular age-related macular degeneration and diabetic macular edema as important examples. Advances continue, with novel therapies such as complement inhibitors now available as treatment for geographic atrophy secondary to non-neovascular age-related macular degeneration, offering hope for a previously untreatable condition. Pioneering approaches such as the port delivery system and intravitreal gene therapy aim to improve treatment efficacy while minimizing patient burden. Despite notable successes, challenges for intravitreal therapies persist, including ocular and systemic complications and high treatment burden. Future research endeavors aim to address these challenges and enhance treatment outcomes. This comprehensive review critically evaluates the efficacy, safety, and cost-effectiveness of intravitreal injections, delving into emerging trends and future directions.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":" ","pages":"162-174"},"PeriodicalIF":1.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12031929/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Telemedicine in ophthalmology.","authors":"Marina Casazza, Matthias Bolz, Josef Huemer","doi":"10.1007/s10354-025-01081-z","DOIUrl":"https://doi.org/10.1007/s10354-025-01081-z","url":null,"abstract":"<p><p>Since its beginnings in the 1970s, telemedicine has advanced extensively. Telemedicine is now more accessible and powerful than ever thanks to developments in medical imaging, Internet accessibility, advancements in telecommunications infrastructure, exponential growth in computing power, and related computer-aided diagnoses. This is especially true in the field of ophthalmology. With the COVID 19 pandemic serving as a catalyst for the widespread adoption and acceptance of teleophthalmology, new models of healthcare provision integrating telemedicine are needed to meet the challenges of the modern world. The demand for ophthalmic services is growing globally due to population growth, aging, and a shortage of ophthalmologists. In this review, we discuss the development and use of telemedicine in the field of ophthalmology and shed light on the benefits and drawbacks of teleophthalmology.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":"175 7-8","pages":"153-161"},"PeriodicalIF":1.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144013054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A historical view of the development of corneal transplantation: from penetrating keratoplasty to selective transplantation of the finest corneal layers.","authors":"Katharina A Heger, Daniel Egger, Gerald Schmidinger, Christian Skorpik, Sebastian M Waldstein, Niklas Pircher","doi":"10.1007/s10354-025-01077-9","DOIUrl":"10.1007/s10354-025-01077-9","url":null,"abstract":"<p><p>Replacement of damaged corneal tissue with a clear transplant represents a viable solution for restoring vision in patients with corneal blindness. Among organ transplants, corneal transplantation occupies a unique status due to the cornea's lack of vascularization. This avascular nature makes immune compatibility testing between donor and recipient unnecessary and reduces the risk of transplant rejection, making corneal transplantation the most successful organ transplant procedure worldwide. Over the past century, corneal transplantation has undergone a transformative journey, evolving from full-thickness keratoplasty to highly refined techniques that selectively target individual diseased corneal layers. These modern lamellar approaches aim for faster recovery times and reduced rejection rates. The global demand for corneal graft tissue far exceeds the availability of donor tissue, leading to prolonged waiting times for patients in need of transplantation. Modern therapeutic strategies are expected to support or potentially even replace transplantation of corneal layers in the future.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":" ","pages":"175-185"},"PeriodicalIF":1.1,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The impact of an emercency form on the place of death of palliative care patients].","authors":"Günter Polt, Gerold Muhri, Anna Theresia Schultz, Erwin Stolz","doi":"10.1007/s10354-024-01058-4","DOIUrl":"10.1007/s10354-024-01058-4","url":null,"abstract":"&lt;p&gt;&lt;p&gt;A pilot study conducted by our research group in 2019 showed that a decision made in advance about the transfer of palliative care patients documented within the emergency information was associated with the actual place of death, thus realizing the patient's wishes regarding the place of death. There were also details on how the scope, duration, and frequency of home visits by mobile palliative care teams should be designed in order to fulfill patients' wishes regarding the place of death. Systematic reviews point to a discrepancy between preferred and actual places of death and a lack of prospective studies and data to support patients and their caregivers.The current observational study lasted one year, included all mobile palliative care teams for adults working in Styria and collected data from a total of 1425 patients (52.6% men). The median age at the time of death was 78.1 years (IQR = 17.4). 76.9% of the sample were cancer patients. Other diseases included cardiovascular (6.3%), neurological (4.1%) and respiratory diseases (2.3%).The emergency information used in this study was an optimized version of the emergency information used in the 2019 pilot, based on input from all palliative care teams who participated in 2019.A total of 109 patients (7.6%) of the entire sample took part in the intervention (emergency information). Of these, 85 individuals (78.9% of the intervention group) indicated a preference for on-side treatment, i.e., without transfer. Only 8 patients (7.3%) indicated a preference for transfer and 16 (14.7%) did not indicate a preference. Of the 85 patients who did not wish to be transferred, 75 (88.2%) died at home, i.e., in around 9 out of 10 cases the patient's wishes were complied with. In contrast, of the 8 people who requested transfer, only 3 (37.5%) died at home, i.e., the majority (5 or 62.5%) died in hospital or a palliative care unit, indicating that the patient's wishes were complied with in the majority of cases.The preference expressed in the emergency information for on-site treatment and against transfer was associated with a more than five times higher odds (p &lt; 0.001) of actually dying at home. The preference expressed in the emergency information increased the probability of dying at home from 63% in the control group to 89% in the intervention group.There was also a significant difference according to the number of medical contacts, i.e. patients who took part in the intervention and did not wish to be transferred had twice as many contacts with physicians (p = 0.031).The results of the logistic regression model also suggested an influence of age, disease and intensity of care by physicians on the odds of dying at home: Older people and the minority of palliative care patients who did not suffer from cancer had higher odds of dying at home than those with cancer. While there was no correlation between the duration of care and the total number of care contacts, the odds of dying at home increased ","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":" ","pages":"110-116"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142628883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frequency and risk factors of nosocomial infections in a trauma center: a case study from the Beni Suef University Hospital, Egypt.","authors":"Moaz Beni Melhem, Manal M Yasser, Aya I Tagyan, Shimaa S Khaled, M Sayed Mohamed, Dalal Hussien M Alkhalifah, Wael N Hozzein","doi":"10.1007/s10354-024-01059-3","DOIUrl":"10.1007/s10354-024-01059-3","url":null,"abstract":"<p><strong>Background and objective: </strong>Hospital-acquired infections (HAI) cause a significant risk to patient maintenance and wellbeing, particularly within the specialized environment of a trauma center. This study focuses on investigating the frequency of HAI in a trauma center through a comprehensive surveillance and monitoring system.</p><p><strong>Methods: </strong>This observational study, conducted between January 2023 and June 2023, focused on the 16-bed trauma center. HAI diagnoses were based on the centers for disease control and prevention (CDC) definitions that typically include specific criteria for different types of infections, for example, urinary tract infections, surgical site infections, bloodstream infections, and others.</p><p><strong>Results: </strong>Among the 160 trauma center-admitted patients, 89 were included in the study. 44 patients contracted HAI, resulting in a frequency of 49.4%. The incidence rates (IR) were 21/1000 central venous catheter (CVC) days for catheter-related bloodstream infections (CRBSI), 10/100 urinary catheter days for catheter-associated urinary tract infections (CAUTI), and 34/1000 ventilator days for ventilator-associated pneumonia (VAP).</p><p><strong>Conclusion: </strong>The HAI percentages noticed in the trauma center are comparatively lower than those reported in other developing country hospitals. The incidence of VAP aligns with findings from other studies.</p>","PeriodicalId":23882,"journal":{"name":"Wiener medizinische Wochenschrift","volume":" ","pages":"117-127"},"PeriodicalIF":1.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142628906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}