Zeitschrift fur Gastroenterologie最新文献_第3页

[When Digital Meets Diagnostics: E-Learning Effectiveness in Internal Medicine Sonography Training]. [当数字遇上诊断：内科超声培训中的电子学习效果]。

IF 1.6 4区医学

Zeitschrift fur Gastroenterologie Pub Date : 2026-02-26 DOI: 10.1055/a-2802-7950

Johannes Weimer, Klaus Dirks, Michael Ludwig, Daniel Merkel, Norbert Börner, Florian Recker, Andreas Weimer, Lukas Müller, Roman Kloeckner, Liv Annebritt Weimer, Leonie Horn, Christoph F Dietrich, Johannes Peter Ruppert, Julia Weinmann-Menke

{"title":"[When Digital Meets Diagnostics: E-Learning Effectiveness in Internal Medicine Sonography Training].","authors":"Johannes Weimer, Klaus Dirks, Michael Ludwig, Daniel Merkel, Norbert Börner, Florian Recker, Andreas Weimer, Lukas Müller, Roman Kloeckner, Liv Annebritt Weimer, Leonie Horn, Christoph F Dietrich, Johannes Peter Ruppert, Julia Weinmann-Menke","doi":"10.1055/a-2802-7950","DOIUrl":"https://doi.org/10.1055/a-2802-7950","url":null,"abstract":"Sonography is a key component of internal medicine diagnostics, making the teaching of basic sonographic skills essential. This study aimed to evaluate the effectiveness of an abdominal-sonography-specific e-learning intervention.In this prospective controlled study, medical students were assessed before (T1) and after (T2) completion of the e-learning within a blended-learning framework. At T2, competence levels and evaluation outcomes were additionally compared with a reference group of physicians who had used the same module to prepare for a certified abdominal ultrasound course. Objective theoretical competencies were measured via written tests; subjective competencies and acceptance were assessed using 7-point Likert scales. Demographic data and usage behavior were also collected.A total of 191 participants were included (144 students, 47 physicians). Students showed significant improvements in objective and subjective competence domains (each p < 0.001). Physicians rated their competencies higher, whereas test scores did not differ significantly between groups (p = 0.07) at T2. Both groups rated the e-learning highly (mean >6.0 scalepoints). Completion time and number of completed modules were relevant influencing factors.The demonstrated competence gains and high acceptance highlight the potential of integrating digital learning resources more extensively into ultrasound education.","PeriodicalId":23853,"journal":{"name":"Zeitschrift fur Gastroenterologie","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147310748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chronic Watery Diarrhea With Colonic Intraepithelial Lymphocytosis Refractory To Budesonide Treatment - A Case Report. 布地奈德治疗难治性慢性水样腹泻伴结肠上皮内淋巴细胞增多1例。

IF 1.6 4区医学

Zeitschrift fur Gastroenterologie Pub Date : 2026-02-01 Epub Date: 2026-01-08 DOI: 10.1055/a-2722-1140

Markus Reiser, Benita Pawlak, Frank Oehmen, Edin Zahirovic, Klaus J Schmitz

{"title":"Chronic Watery Diarrhea With Colonic Intraepithelial Lymphocytosis Refractory To Budesonide Treatment - A Case Report.","authors":"Markus Reiser, Benita Pawlak, Frank Oehmen, Edin Zahirovic, Klaus J Schmitz","doi":"10.1055/a-2722-1140","DOIUrl":"10.1055/a-2722-1140","url":null,"abstract":"Intraepithelial lymphocytosis is a hallmark of microscopic colitis commonly presenting with debilitating chronic watery diarrhea. The exact pathophysiology remains unclear but is believed to involve an abnormal immune response to the luminal microenvironment in genetically predisposed individuals. Medications like nonsteroidal anti-inflammatory drugs, proton pump inhibitors, and antidepressants, as well as alcohol consumption and smoking have been regarded as risk factors for microscopic colitis. Lymphocytic colitis often responds well to anti-inflammatory treatment, with budesonide being a first line therapy. Relapse is common after discontinuing budesonide, often necessitating low-dose maintenance therapy. Advanced therapies including anti-TNF-alpha (e.g. infliximab) or anti-integrin (e.g. vedolizumab) agents as well as JAK inhibitors (e.g. upadacitinib) may be considered in refractory cases. However, confirmation of the diagnosis and ruling out other etiologies are necessary before intensifying treatment. Here, we present the case of a 78-year-old female patient with a twenty month history of chronic refractory diarrhea, repeatedly diagnosed as microscopic lymphocytic colitis. Following further deterioration and the development of hepatosplenomegaly with atypical liver lesions, a review of colonic biopsies and additional work-up led to the correct diagnosis.","PeriodicalId":23853,"journal":{"name":"Zeitschrift fur Gastroenterologie","volume":" ","pages":"179-183"},"PeriodicalIF":1.6,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145935306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chronic Imbalance? Gender Disparities in Gastroenterology Across a Decade of the Visceral Medicine Congress in Germany. 慢性不平衡?德国内脏医学大会十年来胃肠病学的性别差异。

IF 1.6 4区医学

Zeitschrift fur Gastroenterologie Pub Date : 2026-02-01 Epub Date: 2025-10-07 DOI: 10.1055/a-2701-1372

Jennifer Gill, Lea Pueschel, Marie-Louise Witte, Birgit Terjung, Petra Lynen Jansen, Heiner Wedemeyer, Henrike Lenzen, Miriam Wiestler

{"title":"Chronic Imbalance? Gender Disparities in Gastroenterology Across a Decade of the Visceral Medicine Congress in Germany.","authors":"Jennifer Gill, Lea Pueschel, Marie-Louise Witte, Birgit Terjung, Petra Lynen Jansen, Heiner Wedemeyer, Henrike Lenzen, Miriam Wiestler","doi":"10.1055/a-2701-1372","DOIUrl":"10.1055/a-2701-1372","url":null,"abstract":"Despite efforts toward gender equality, disparities persist in medical careers and leadership. This study examines gender representation in gastroenterology at the German Visceral Medicine Congress from 2013 to 2024, focusing on changes over time.Programs from 1,333 sessions were analyzed for gender ratios of speakers and chairs, including plenary, ab-stract, and industry sessions, plus congress presidents and awardees. Trends were assessed via linear regression and Cochran-Armitage tests.Trend analysis revealed a significant increase in female speakers (r²=0.599, p=0.005) and chairpersons (r²=0.747, p<0.001). Female speaker proportions rose significantly in plenary (r²=0.600, p=0.005), abstract (r²=0.445, p=0.025), and industry sessions (r²=0.641, p=0.003), but did not reach parity. Female chairs showed stronger upward trends: plenary (r²=0.807, p<0.001), abstract (r²=0.490, p=0.016), industry (r²=0.729, p<0.001). Congress presidencies remained all male, and 75-93% of awards went to men.Female representation, especially in chair roles, has improved since the 2019 parity resolution but remains insufficient in key areas. Ongoing gender-sensitive planning and support are needed to foster a more inclusive academic environment.","PeriodicalId":23853,"journal":{"name":"Zeitschrift fur Gastroenterologie","volume":" ","pages":"168-178"},"PeriodicalIF":1.6,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13077563/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145245485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Crohn's Disease Exclusion Diet (CDED) and partial enteral nutrition (PEN) for remission induction in children and adolescents with Crohn's Disease - Updated statement from the CEDATA and Nutrition/Dietetics/Nutritional Medicine Working Groups of the Society for paediatric Gastroenterology and Nutrition (GPGE)]. [克罗恩病排除饮食（CDED）和部分肠内营养（PEN）用于诱导克罗恩病儿童和青少年缓解-来自CEDATA和儿科胃肠病学和营养学会（GPGE）营养/营养学/营养医学工作组的最新声明]。

IF 1.6 4区医学

Zeitschrift fur Gastroenterologie Pub Date : 2026-02-01 Epub Date: 2026-02-19 DOI: 10.1055/a-2699-7377

Evdokia Alexanidou, André Hörning, Jan de Laffolie, Anjona Schmidt-Choudhury, Jan Däbritz, Ag Ernährung Und Cedata-Studiengruppe

引用次数: 0

Evaluating Long-Term Functional and Symptomatic Outcomes of Pneumatic Dilatation in Achalasia: An Experience from Pakistan. 评估贲门失弛缓症气动扩张的长期功能和症状结果：来自巴基斯坦的经验。

IF 1.6 4区医学

Zeitschrift fur Gastroenterologie Pub Date : 2026-02-01 Epub Date: 2026-01-12 DOI: 10.1055/a-2707-1799

Sameen Abbas, Kanza Zahid, Bilal Ashraf, Tayyab Saeed Akhtar, Saima Mushtaq, Abdul Wahid, Amjad Khan

{"title":"Evaluating Long-Term Functional and Symptomatic Outcomes of Pneumatic Dilatation in Achalasia: An Experience from Pakistan.","authors":"Sameen Abbas, Kanza Zahid, Bilal Ashraf, Tayyab Saeed Akhtar, Saima Mushtaq, Abdul Wahid, Amjad Khan","doi":"10.1055/a-2707-1799","DOIUrl":"10.1055/a-2707-1799","url":null,"abstract":"Achalasia, a rare esophageal motility disorder, is managed with medications, botulinum toxin, pneumatic dilation (PD), or surgery. In resource-limited settings like Pakistan, PD is preferred first-line non-surgical treatment due to its accessibility and cost-effectiveness so we aim to assess remission rates and clinical outcomes of PD.Between 2015 and 2024, 213 achalasia patients were diagnosed via HRM at Center for Liver & Digestive Diseases, Holy Family Hospital, Rawalpindi. 191 patients opted for PD and completed follow-up interviews using Eckardt score and ASQ questionnaire. Data analysis was performed using SPSS.Among 191 patients (107 males, 84 females), 53% underwent one, 30% two, and 17% three PD session. Success rates were 58% for one, 78% for two, and 87.5% for three sessions, with no severe complications. The cumulative re-dilation rate was 20%, with a 76% success rate for repeat dilations. Multiple PDs significantly outperformed single PDs(p=0.01), reducing mean Eckardt score from 6.7 to 1.9. QoL improved with successful dilations but not in failed cases.PD provides sustained symptom relief for up to five years, with repeat sessions enhancing long-term success, reinforcing PD as an effective, durable, and accessible treatment option for achalasia in low-resource settings for evidence-based clinical decision-making.","PeriodicalId":23853,"journal":{"name":"Zeitschrift fur Gastroenterologie","volume":" ","pages":"147-156"},"PeriodicalIF":1.6,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145960425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Post-induction serum vedolizumab levels are not associated with better maintenance outcomes in patients with Crohn's disease. 诱导后血清vedolizumab水平与克罗恩病患者更好的维持结果无关。

IF 1.6 4区医学

Zeitschrift fur Gastroenterologie Pub Date : 2026-02-01 Epub Date: 2026-01-12 DOI: 10.1055/a-2744-5136

Jagoda Pokryszka, Christian Primas, Michael Stadlmann, Nathalie Gerold, Cornelia Lichtenberger, Sieglinde Reinisch, Gottfried Novacek, Walter Reinisch

{"title":"Post-induction serum vedolizumab levels are not associated with better maintenance outcomes in patients with Crohn's disease.","authors":"Jagoda Pokryszka, Christian Primas, Michael Stadlmann, Nathalie Gerold, Cornelia Lichtenberger, Sieglinde Reinisch, Gottfried Novacek, Walter Reinisch","doi":"10.1055/a-2744-5136","DOIUrl":"10.1055/a-2744-5136","url":null,"abstract":"Results on exposure-efficacy relationships for vedolizumab in patients with Crohn's disease are contentious. Our study aimed at exploring the relationship between vedolizumab serum concentrations measured during induction and maintenance and treatment outcomes in Crohn's disease patients in a real-world setting.Crohn's disease patients treated with vedolizumab between January 2014 and July 2022 at our tertiary care centre were included. Serum vedolizumab concentrations were measured on at least one of the following time points: week 2, 6, 12, 26, and/or 52. Treatment efficacy was evaluated at weeks 12, 26 and 52 as clinical remission based on patients reported outcomes, faecal calprotectin and C-reactive protein remission.In total, 58 patients (55.2% females) were included. At baseline, active disease, defined either by increased faecal calprotectin, C-reactive protein or patients reported outcomes, was observed in 53 patients (91.4%). Week 12 vedolizumab serum levels were higher in clinical remitters versus non-remitters at weeks 12 and 52 (p <0.05). However, in adjusted multivariate analyses no association between vedolizumab levels and therapy outcomes was observed.In our retrospective study, vedolizumab serum concentrations measured during induction treatment were not associated with clinical and feacal calprotecin remission at weeks 12, 26 and 52.","PeriodicalId":23853,"journal":{"name":"Zeitschrift fur Gastroenterologie","volume":" ","pages":"157-167"},"PeriodicalIF":1.6,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13077553/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145960410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Correction: Crohn's Disease Exclusion Diet (CDED) and partial enteral nutrition (PEN) for remission induction in children and adolescents with Crohn's Disease - Updated statement from the CEDATA and Nutrition/Dietetics/Nutritional Medicine Working Groups of the Society for paediatric Gastroenterology and Nutrition (GPGE)]. [更正：克罗恩病排除饮食（CDED）和部分肠内营养（PEN）用于诱导克罗恩病儿童和青少年缓解-来自CEDATA和儿科胃肠病学和营养学会（GPGE）营养/营养学/营养医学工作组的最新声明]。

IF 1.6 4区医学

Zeitschrift fur Gastroenterologie Pub Date : 2026-02-01 Epub Date: 2026-03-13 DOI: 10.1055/a-2832-4619

Evdokia Alexanidou, André Hörning, Jan de Laffolie, Anjona Schmidt-Choudhury, Jan Däbritz, Ag Ernährung Und Cedata-Studiengruppe

引用次数: 0

[93-year old patient with pain of the right lower abdomen]. [93岁患者右下腹疼痛]。

IF 1.6 4区医学

Zeitschrift fur Gastroenterologie Pub Date : 2026-02-01 Epub Date: 2026-02-19 DOI: 10.1055/a-2688-8397

Annekatrin Schwanstecher, Joachim C Arnold

引用次数: 0

[11 tips for effective university teaching of sonography]. [大学超声检查教学的11个技巧]。

IF 1.6 4区医学

Zeitschrift fur Gastroenterologie Pub Date : 2026-01-08 DOI: 10.1055/a-2761-5182

Lisa Groth, Johannes Weimer, Carlotta Ille, Florian Recker

{"title":"[11 tips for effective university teaching of sonography].","authors":"Lisa Groth, Johannes Weimer, Carlotta Ille, Florian Recker","doi":"10.1055/a-2761-5182","DOIUrl":"https://doi.org/10.1055/a-2761-5182","url":null,"abstract":"The integration of sonography into medical studies offers a wide range of opportunities, but also presents teachers with complex challenges. Teaching theoretical and practical sonographic skills requires not only technical expertise, but also sound didactic and communication skills on the part of the teachers. The aim of this study is to provide sonography teachers with sound recommendations for effective teaching based on current evidence.National and international studies on sonography training and didactics were evaluated as part of a systematic literature review. The findings were grouped by topic, structured using a consensus process, and presented in the form of practical guidelines. The analysis was based on the PRISMA criteria and supplemented by a narrative synthesis.Eleven didactically sound recommendations for sonography teaching were formulated, including: optimal group sizes, establishment of peer teaching, early curricular integration, use of modern technologies (e.g., AI, VR), use of appropriate teaching and learning materials and didactic methods, targeted teaching of psychomotor skills, and the inclusion of ethical aspects. All of the recommendations mentioned have been proven to be relevant, practicable, and didactically effective in the literature and were classified and explained in terms of content.The results show that high-quality sonography training is more than just technical training: it requires educational planning and didactic sensitivity. The tips presented here offer guidance and inspiration for reflective, evidence-based, and learner-centered teaching practices. They not only promote the acquisition of skills by students, but also the further development of the teachers themselves-towards sustainable, interprofessionally compatible sonography training.","PeriodicalId":23853,"journal":{"name":"Zeitschrift fur Gastroenterologie","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2026-01-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145935267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[70-year-old patient with recurrent lower gastrointestinal bleeding without a source of bleeding?] 70岁无出血来源复发性下消化道出血患者？]

IF 1.6 4区医学

Zeitschrift fur Gastroenterologie Pub Date : 2026-01-01 Epub Date: 2026-01-26 DOI: 10.1055/a-2702-9485

Matthias Breidert, Sabrina Christann, Ulrich Dietz

引用次数: 0