Zeitschrift fur Rheumatologie最新文献_第7页

Mitteilungen der DRL. DRL通讯。

IF 1.2 4区医学

Zeitschrift fur Rheumatologie Pub Date : 2026-08-01 DOI: 10.1007/s00393-026-01853-x

引用次数: 0

[Evidence-based management of acute-phase reaction following zoledronic acid]. [唑来膦酸急性期反应的循证管理]。

IF 1.2 4区医学

Zeitschrift fur Rheumatologie Pub Date : 2026-08-01 Epub Date: 2026-05-12 DOI: 10.1007/s00393-026-01827-z

Nils Schulz, Philipp Klemm

引用次数: 0

Pediatric neurosarcoidosis with cavernous sinus involvement and internal carotid artery stenosis. 小儿神经结节病伴海绵窦受累及颈内动脉狭窄。

IF 1.2 4区医学

Zeitschrift fur Rheumatologie Pub Date : 2026-07-28 DOI: 10.1007/s00393-026-01857-7

Aybuke Alisan, Seyda Besen, Rabia Miray Kisla Ekinci, Aysun Uguz, Ummuhan Cay, Oya Baydar, Ozlem Alkan, Ilknur Erol

{"title":"Pediatric neurosarcoidosis with cavernous sinus involvement and internal carotid artery stenosis.","authors":"Aybuke Alisan, Seyda Besen, Rabia Miray Kisla Ekinci, Aysun Uguz, Ummuhan Cay, Oya Baydar, Ozlem Alkan, Ilknur Erol","doi":"10.1007/s00393-026-01857-7","DOIUrl":"https://doi.org/10.1007/s00393-026-01857-7","url":null,"abstract":"Sarcoidosis is a rare multisystemic disease characterized by noncaseating granulomas. Pediatric-onset adult-type sarcoidosis is extremely rare, and neurological involvement is scarce in this population. Herein, we report on a 14-year-old girl presenting with headache, weight loss, lateral gaze palsy, and a long-lasting history of unilateral hilar lymphadenopathy. Erythroid sedimentation rate (42 mm/h) and C‑reactive protein (61 mg/L) were both elevated. Cerebrospinal fluid pressure was elevated (36 cm/H2O), and pseudotumor cerebri was suspected. Brain magnetic resonance imaging (MRI) showed an extra-axial dural-based lesion, extending along the right tentorium to the cavernous sinus, Meckel's cave, the dura of the middle cranial fossa, and the prepontine cistern. Given the substantial life-threatening risks associated with intracranial biopsy, tissue sampling was obtained from the right hilar lymph node. The biopsy revealed noncaseating granulomatous lymphadenitis. After excluding other diagnoses, including immunoglobulin G4-related disease, Wegener's disease, tuberculosis, lymphoma, or lymphohistiocytosis, we eventually established the diagnosis of sarcoidosis. The patient received systemic steroids and subcutaneous methotrexate treatment in the first line. Three months later, due to absence of lesion regression in MRI and the life-threatening potential of the lesion, we initiated intravenous monthly infliximab. Radiological remission was achieved with three doses of monthly infliximab. Systemic steroids were tapered to 4 mg/day thereafter, and infliximab was continued bimonthly after six doses of monthly treatment. Systemic steroids were discontinued at the ninth month of treatment. The patient is symptom free and had no treatment side effects during follow-up.","PeriodicalId":23834,"journal":{"name":"Zeitschrift fur Rheumatologie","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148608048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Erratum zu: Prävention der rheumatoiden Arthritis. Von der Primärprävention zur medikamentösen Interzeption. “类风湿关节炎的预防”。从初级预防到药物治疗。

IF 1.2 4区医学

Zeitschrift fur Rheumatologie Pub Date : 2026-07-21 DOI: 10.1007/s00393-026-01856-8

Jürgen Rech

引用次数: 0

[This is how I treat IgG4-related disease]. 这就是我治疗igg4相关疾病的方法。

IF 1.2 4区医学

Zeitschrift fur Rheumatologie Pub Date : 2026-07-13 DOI: 10.1007/s00393-026-01845-x

Felix Müller

引用次数: 0

Nachruf auf Dr. Frank Demtröder : *21.10.1957 †26.05.2026. 弗兰克博士的讣告Demtroder（1957年10月21日- 2026年5月26日）。

IF 1.2 4区医学

Zeitschrift fur Rheumatologie Pub Date : 2026-07-07 DOI: 10.1007/s00393-026-01850-0

Matthias Schneider, Dieter Wiek

引用次数: 0

[Not measurable but immeasurably important : Fever-The leading symptom of ancient medical theory]. [不可测量但不可测量的重要：发烧——古代医学理论的主要症状]。

IF 1.2 4区医学

Zeitschrift fur Rheumatologie Pub Date : 2026-06-17 DOI: 10.1007/s00393-026-01843-z

Werner Golder, Waltraud Golder

引用次数: 0

Moderne Wissensvermittlung in der Rheumatologie. 风湿病学研究。

IF 1 4区医学

Zeitschrift fur Rheumatologie Pub Date : 2026-06-01 Epub Date: 2026-06-03 DOI: 10.1007/s00393-026-01825-1

Gerd R Burmester, Martin Krusche

引用次数: 0

Lung-only involvement in STING-associated vasculopathy with onset in infancy: a diagnostic pitfall in the absence of cutaneous vasculitis. 婴儿期发作的sting相关血管病变仅累及肺部：缺乏皮肤血管炎的诊断缺陷。

IF 1.2 4区医学

Zeitschrift fur Rheumatologie Pub Date : 2026-06-01 Epub Date: 2026-01-06 DOI: 10.1007/s00393-025-01768-z

Rabia Miray Kisla Ekinci, Ummuhan Cay, Deniz Kor, Hasan Ali Telefon, Faruk Ekinci, Ozden Ozgur Horoz, Dincer Yildizdas

{"title":"Lung-only involvement in STING-associated vasculopathy with onset in infancy: a diagnostic pitfall in the absence of cutaneous vasculitis.","authors":"Rabia Miray Kisla Ekinci, Ummuhan Cay, Deniz Kor, Hasan Ali Telefon, Faruk Ekinci, Ozden Ozgur Horoz, Dincer Yildizdas","doi":"10.1007/s00393-025-01768-z","DOIUrl":"10.1007/s00393-025-01768-z","url":null,"abstract":"Background: STING-associated vasculopathy with onset in infancy (SAVI) is a rare monogenic autoinflammatory disorder. It is characterized by excessive interferon activity due to gain-of-function mutations in the STING1 gene, resulting in skin lesions and lung involvement. Some patients may also present with interstitial lung disease (ILD) only. While treatment with JAK inhibitors like baricitinib has shown some promise, long-term success is limited.Case presentation: We report on a 10-month-old male suffering from respiratory distress since birth. He demonstrated failure to thrive and progressive ILD. The patient lacked skin lesions, arthritis, hepatosplenomegaly, lymphadenopathy, and any clues indicating vasculitis. Erythroid sedimentation rate was normal, and C‑reactive protein (CRP) was slightly elevated. However, CRP became elevated to 115 mg/L during the course of disease. Despite antibiotics and steroids, his condition deteriorated. Chest imaging revealed features suggestive of ILD, prompting further investigation. Whole-exome sequencing confirmed a heterozygotic c.461A > G (p.Asn154Ser) variant in the STING1 gene, thereby diagnosing the patient with SAVI. Despite treatment with baricitinib and tocilizumab, his condition worsened, and he ultimately passed away.Conclusion: This case highlights that SAVI should be considered in the differential diagnosis of ILD, even without typical skin lesions.","PeriodicalId":23834,"journal":{"name":"Zeitschrift fur Rheumatologie","volume":" ","pages":"390-394"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145913137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Combination therapy with mycophenolate mofetil, nintedanib, and tocilizumab in a patient with progressive systemic sclerosis-associated interstitial lung disease : A case report and a literature review. 霉酚酸酯、尼达尼布和托珠单抗联合治疗进行性系统性硬化症相关间质性肺病1例报告和文献综述

IF 1.2 4区医学

Zeitschrift fur Rheumatologie Pub Date : 2026-06-01 Epub Date: 2026-03-05 DOI: 10.1007/s00393-026-01776-7

Liangyu Chen, Xiaoxuan Li, Donghui Huang, Peisheng Chen, Pan Xu, Huihui Chen, Xiao Zhang

引用次数: 0