Zeitschrift fur Rheumatologie最新文献_第6页

Mitteilungen der DGRh. DGR通讯。

IF 0.9 4区医学

Zeitschrift fur Rheumatologie Pub Date : 2024-12-01 DOI: 10.1007/s00393-024-01605-9

引用次数: 0

Mitteilungen der DRL. DRL通讯。

IF 0.9 4区医学

Zeitschrift fur Rheumatologie Pub Date : 2024-12-01 DOI: 10.1007/s00393-024-01601-z

引用次数: 0

All-cause and cause-specific mortality in rheumatoid arthritis: a meta-analysis. 类风湿性关节炎的全因和特因死亡率：一项荟萃分析。

IF 0.9 4区医学

Zeitschrift fur Rheumatologie Pub Date : 2024-12-01 Epub Date: 2024-06-25 DOI: 10.1007/s00393-024-01538-3

Young Ho Lee, Gwan Gyu Song

{"title":"All-cause and cause-specific mortality in rheumatoid arthritis: a meta-analysis.","authors":"Young Ho Lee, Gwan Gyu Song","doi":"10.1007/s00393-024-01538-3","DOIUrl":"10.1007/s00393-024-01538-3","url":null,"abstract":"Objective: This study aimed to evaluate standardized mortality ratios (SMRs) for both all-cause and cause-specific mortality in patients with rheumatoid arthritis (RA).Methods: We conducted an extensive search across the Medline, Embase, and Cochrane databases to identify studies investigating SMRs for all-cause and/or cause-specific mortality in individuals with RA compared to the general population. Subsequently, we performed a comprehensive meta-analysis, examining SMRs across various categories, including all-cause, sex-specific, ethnicity-specific, and cause-specific SMRs in RA patients.Results: Seventeen studies involving 486,098 patients with RA and 63,988 deaths met the inclusion criteria. Patients with RA had a 1.522-fold increase in all-cause SMR (SMR 1.522, 95% CI 1.340-1.704, p < 0.001) compared to the general population. Stratification by ethnicity revealed that the all-cause SMR was 1.575 (95% CI 1.207-1.943) in Caucasians and 1.355 (95% CI 1.140-1.569) in Asians. The gender-specific meta-analysis revealed elevated SMR in both women and men. RA patients exhibited an increased risk of mortality attributed to cardiovascular disease (CVD), respiratory disease, infection, and cerebrovascular accidents (CVA). However, no significant increase in SMR was observed for mortality due to malignancy.Conclusion: This meta-analysis study highlights a 1.522-fold increase in SMR in patients with RA compared to that in the general population, irrespective of sex or region. Additionally, a notable increase in mortality associated with specific causes, including CVD, respiratory disease, infection, and CVA, underscores the critical need for targeted interventions to manage these heightened risks in patients with RA.","PeriodicalId":23834,"journal":{"name":"Zeitschrift fur Rheumatologie","volume":" ","pages":"314-320"},"PeriodicalIF":0.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141451691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A meta-analysis of melanoma risk in idiopathic inflammatory myopathy patients. 特发性炎症性肌病患者黑色素瘤风险的荟萃分析。

IF 0.9 4区医学

Zeitschrift fur Rheumatologie Pub Date : 2024-12-01 Epub Date: 2024-01-29 DOI: 10.1007/s00393-024-01473-3

Rui Luo, Dan Xia, Siyang Yu

{"title":"A meta-analysis of melanoma risk in idiopathic inflammatory myopathy patients.","authors":"Rui Luo, Dan Xia, Siyang Yu","doi":"10.1007/s00393-024-01473-3","DOIUrl":"10.1007/s00393-024-01473-3","url":null,"abstract":"Background: Idiopathic inflammatory myopathy (IIM) is a group of chronic acquired autoimmune diseases. The association between IIM and malignancies has been observed for decades. No meta-analysis has been conducted to summarize the relationship between IIM and melanoma. Herein, we specifically wanted to investigate whether IIM is associated with a higher incidence of melanoma.Methods: We searched both Chinese and English databases (CNKI, VIP, Wanfang, PubMed, Embase, Web of Science) for studies on IIM related to melanoma published up to October 2023. Two independent authors reviewed all literature to identify studies according to predefined selection criteria. Fixed effects models were applied to pool the risk. Publication bias was also evaluated and sensitivity analysis performed.Results: A total of 1660 articles were initially identified but only four cohort studies met the criteria. Thus, 4239 IIM patients were followed up. The pooled overall risk ratio/hazard ratio was 3.08 (95% confidence interval [CI] 0.79-5.37) and the standardized incidence ratio was 6.30 (95% CI 1.59-11.02).Conclusion: The present meta-analysis suggests that IIM patients are at a significantly higher risk of developing melanoma.","PeriodicalId":23834,"journal":{"name":"Zeitschrift fur Rheumatologie","volume":" ","pages":"299-304"},"PeriodicalIF":0.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11655601/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139571483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Immunologic derangement caused by intestinal dysbiosis and stress is the intrinsic basis of reactive arthritis. 肠道菌群失调和压力导致的免疫失调是反应性关节炎的内在基础。

IF 0.9 4区医学

Zeitschrift fur Rheumatologie Pub Date : 2024-12-01 Epub Date: 2024-02-25 DOI: 10.1007/s00393-024-01480-4

Tao He, Weiqing Qian

{"title":"Immunologic derangement caused by intestinal dysbiosis and stress is the intrinsic basis of reactive arthritis.","authors":"Tao He, Weiqing Qian","doi":"10.1007/s00393-024-01480-4","DOIUrl":"10.1007/s00393-024-01480-4","url":null,"abstract":"Reactive arthritis (ReA) is defined as arthritis resulting from infections in other body parts, such as the gastrointestinal and urogenital tracts. The primary clinical manifestations involve acute-onset and self-limiting asymmetric large joint inflammation in the lower limbs. Although bacterial or chlamydia infections have long been recognized as playing a pivotal role in its pathogenesis, recent studies suggest that antibiotic treatment may perpetuate rather than eradicate chlamydia within the host, indicating an involvement of other mechanisms in Reactive arthritis. Reactive arthritis is currently believed to be associated with infection, genetic marker (HLA-B27), and immunologic derangement. As an autoimmune disease, increasing attention has been given to understanding the role of the immune system in Reactive arthritis. This review focuses on elucidating how the immune system mediates reactive arthritis and explores the roles of intestinal dysbiosis-induced immune disorders and stress-related factors in autoimmune diseases, providing novel insights into understanding reactive arthritis.","PeriodicalId":23834,"journal":{"name":"Zeitschrift fur Rheumatologie","volume":" ","pages":"305-313"},"PeriodicalIF":0.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11655581/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139973658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Unclear cause of unilateral blindness with normal inflammation parameters]. [炎症指标正常的单侧失明原因不明]。

IF 0.9 4区医学

Zeitschrift fur Rheumatologie Pub Date : 2024-12-01 Epub Date: 2024-06-14 DOI: 10.1007/s00393-024-01531-w

Felix Müller, Christian Helmut Pfob, Matthias Wahle

引用次数: 0

[Vasculitides: new aspects]. 脉管炎：新的方面。

IF 0.9 4区医学

Zeitschrift fur Rheumatologie Pub Date : 2024-12-01 Epub Date: 2024-12-03 DOI: 10.1007/s00393-024-01591-y

Frank Moosig, Julia Holle

引用次数: 0

[Update on Behçet syndrome]. [贝赫切特综合征的最新进展]。

IF 0.9 4区医学

Zeitschrift fur Rheumatologie Pub Date : 2024-12-01 Epub Date: 2024-10-01 DOI: 10.1007/s00393-024-01576-x

Ina Kötter, Nikolas Ruffer, Martin Krusche

{"title":"[Update on Behçet syndrome].","authors":"Ina Kötter, Nikolas Ruffer, Martin Krusche","doi":"10.1007/s00393-024-01576-x","DOIUrl":"10.1007/s00393-024-01576-x","url":null,"abstract":"Background: Behçet syndrome (BS) is a vasculitis of variable vessels with multiple organ manifestations.Objective: This article gives an overview of innovations in the last 2 years.Material and methods: A literature search was carried out using the keyword \"Behcet\" in 2022-2024 in PubMed. The selection of suitable articles was based on the relevance.Results and conclusion: With respect to the pathophysiology it is now clear that BS occupies an intermediate position between autoinflammatory and autoimmune clinical pictures. It is now classified as MHC-I-opathy, i.e., a disease that has a strong association with HLA class I antigens, which also play a prominent role in the pathogenesis. The diagnostic international criteria for Behcet's disease (ICBD) from 2014 with a score of 4 points or more that makes the diagnosis of BS probable have become established; however, in countries with a low prevalence of BS, the differential diagnosis of BS from other diseases is difficult and a higher point limit in the diagnostic score seems to make sense in order to avoid incorrect diagnoses. Clusters or phenotypes of the disease have now been described in various countries in which different symptom complexes frequently occur together; however, the clusters differ between the different countries of origin and depending on the age of the patients. Sonography of the common femoral vein with specific wall thickening in BS patients has been established as an additional tool for the differential diagnosis. Typical characteristics of oral aphthae in BS were also described and the frequency of positivity in the pathergy test could be significantly increased using pneumococcal antigens as the reagent. The treatment recommendations of the EULAR from 2018 still apply; in treatment-refractory cases, tocilizumab, secukinumab, Janus kinase inhibitors (JAKi) and ustekinumab have now also been successfully used. The new EULAR treatment recommendations are expected in 2025.","PeriodicalId":23834,"journal":{"name":"Zeitschrift fur Rheumatologie","volume":" ","pages":"822-828"},"PeriodicalIF":0.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142362145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of gout on cardiovascular disease mortality: a meta-analysis. 痛风对心血管疾病死亡率的影响：一项荟萃分析。

IF 0.9 4区医学

Zeitschrift fur Rheumatologie Pub Date : 2024-12-01 Epub Date: 2024-02-01 DOI: 10.1007/s00393-024-01479-x

Jielin Yuan, Zhitao Xie, Bo Pan, Jingchang Zhang

{"title":"Impact of gout on cardiovascular disease mortality: a meta-analysis.","authors":"Jielin Yuan, Zhitao Xie, Bo Pan, Jingchang Zhang","doi":"10.1007/s00393-024-01479-x","DOIUrl":"10.1007/s00393-024-01479-x","url":null,"abstract":"Background: Several epidemiological studies have suggested that gout patients have a higher risk of cardiovascular disease mortality than healthy people. In contrast, the association between gout and cardiovascular disease (CVD) mortality was not obvious in other studies. In the present study, we aimed to investigate the relative risk for CVD mortality in gout patients in comparison to healthy controls.Methods: Literature published before March 2023 was searched in Google Scholar, PubMed, and the Web of Science. We summarized the impact of gout on CVD mortality with a meta-analysis. Hazard ratios (HRs) and 95% confidence intervals (CIs) regarding the impact of gout on CVD mortality were summarized with STATA 12.0 software.Results: Compared to individuals without gout, those with gout had higher mortality risks for CVD during follow-up, with a random effects model showing a risk of 1.30 (95% CI 1.15 to 1.48, p < 0.001; p-value for Cochran Q test < 0.001, I2 = 95.9%). Similarly, subjects with gout had a mortality risk of 1.28 (95% CI 1.12 to 1.46, p < 0.001; p-value for Cochran Q test = 0.050, I2 = 50.2%) for coronary heart disease (CHD) mortality during follow-up using the same statistical model. Furthermore, using a fixed effects model, individuals with gout had a mortality risk of 1.13 (95% CI 1.00 to 1.27, p = 0.049; p-value for Cochran Q test = 0.494, I2 = 0.0%) for myocardial infarction (MI) mortality during follow-up.Conclusion: In conclusion, this meta-analysis provides evidence supporting a markedly increased mortality risk from CVD and CHD as well as MI in patients with gout relative to reference subjects without gout.","PeriodicalId":23834,"journal":{"name":"Zeitschrift fur Rheumatologie","volume":" ","pages":"329-337"},"PeriodicalIF":0.9,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139672770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Castleman's disease in the rheumatological practice. 风湿病实践中的卡斯特曼病。

IF 0.9 4区医学

Zeitschrift fur Rheumatologie Pub Date : 2024-12-01 Epub Date: 2024-08-22 DOI: 10.1007/s00393-024-01560-5

M Schmalzing, O Sander, M Seidl, R Marks, N Blank, I Kötter, M Tiemann, M Backhaus, B Manger, K Hübel, U Müller-Ladner, J Henes

引用次数: 0