Yun-Feng Zhu, Fan-Yan Yi, Ming-Hui Qin, Ji Lu, Hao Liang, Sen Yang, Yu-Zheng Wei
{"title":"Factors influencing agitation during anesthesia recovery after laparoscopic hernia repair under total inhalation combined with caudal block anesthesia.","authors":"Yun-Feng Zhu, Fan-Yan Yi, Ming-Hui Qin, Ji Lu, Hao Liang, Sen Yang, Yu-Zheng Wei","doi":"10.4240/wjgs.v16.i11.3499","DOIUrl":"10.4240/wjgs.v16.i11.3499","url":null,"abstract":"<p><strong>Background: </strong>Laparoscopic hernia repair is a minimally invasive surgery, but patients may experience emergence agitation (EA) during the post-anesthesia recovery period, which can increase pain and lead to complications such as wound reopening and bleeding. There is limited research on the risk factors for this agitation, and few effective tools exist to predict it. Therefore, by integrating clinical data, we have developed nomograms and random forest predictive models to help clinicians predict and potentially prevent EA.</p><p><strong>Aim: </strong>To establish a risk nomogram prediction model for EA in patients undergoing laparoscopic hernia surgery under total inhalation combined with sacral block anesthesia.</p><p><strong>Methods: </strong>Based on the clinical information of 300 patients who underwent laparoscopic hernia surgery in the Nanning Tenth People's Hospital, Guangxi, from January 2020 to June 2023, the patients were divided into two groups according to their sedation-agitation scale score, <i>i.e.</i>, the EA group (≥ 5 points) and the non-EA group (≤ 4 points), during anesthesia recovery. Least absolute shrinkage and selection operator regression was used to select the key features that predict EA, and incorporating them into logistic regression analysis to obtain potential predictive factors and establish EA nomogram and random forest risk prediction models through R software.</p><p><strong>Results: </strong>Out of the 300 patients, 72 had agitation during anesthesia recovery, with an incidence of 24.0%. American Society of Anesthesiologists classification, preoperative anxiety, solid food fasting time, clear liquid fasting time, indwelling catheter, and pain level upon awakening are key predictors of EA in patients undergoing laparoscopic hernia surgery with total intravenous anesthesia and caudal block anesthesia. The nomogram predicts EA with an area under the receiver operating characteristic curve (AUC) of 0.947, a sensitivity of 0.917, and a specificity of 0.877, whereas the random forest model has an AUC of 0.923, a sensitivity of 0.912, and a specificity of 0.877. Delong's test shows no significant difference in AUC between the two models. Clinical decision curve analysis indicates that both models have good net benefits in predicting EA, with the nomogram effective within the threshold of 0.02 to 0.96 and the random forest model within 0.03 to 0.90. In the external model validation of 50 cases of laparoscopic hernia surgery, both models predicted EA. The nomogram model had a sensitivity of 83.33%, specificity of 86.84%, and accuracy of 86.00%, while the random forest model had a sensitivity of 75.00%, specificity of 78.95%, and accuracy of 78.00%, suggesting that the nomogram model performs better in predicting EA.</p><p><strong>Conclusion: </strong>Independent predictors of EA in patients undergoing laparoscopic hernia repair with total intravenous anesthesia combined with caudal block include Americ","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"16 11","pages":"3499-3510"},"PeriodicalIF":1.8,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622067/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142795291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shuai Shi, Cong Lu, Liang Shan, Liang Yan, Yong Liang, Tao Feng, Zun Chen, Xin Chen, Xi Wu, Si-Da Liu, Xiang-Long Duan, Ze-Zheng Wang
{"title":"Predicting prolonged postoperative ileus in gastric cancer patients based on bowel sounds using intelligent auscultation and machine learning.","authors":"Shuai Shi, Cong Lu, Liang Shan, Liang Yan, Yong Liang, Tao Feng, Zun Chen, Xin Chen, Xi Wu, Si-Da Liu, Xiang-Long Duan, Ze-Zheng Wang","doi":"10.4240/wjgs.v16.i11.3484","DOIUrl":"10.4240/wjgs.v16.i11.3484","url":null,"abstract":"<p><strong>Background: </strong>Prolonged postoperative ileus (PPOI) delays the postoperative recovery of gastrointestinal function in patients with gastric cancer (GC), leading to longer hospitalization and higher healthcare expenditure. However, effective monitoring of gastrointestinal recovery in patients with GC remains challenging because of the lack of noninvasive methods.</p><p><strong>Aim: </strong>To explore the risk factors for delayed postoperative bowel function recovery and evaluate bowel sound indicators collected <i>via</i> an intelligent auscultation system to guide clinical practice.</p><p><strong>Methods: </strong>This study included data from 120 patients diagnosed with GC who had undergone surgical treatment and postoperative bowel sound monitoring in the Department of General Surgery II at Shaanxi Provincial People's Hospital between January 2019 and January 2021. Among them, PPOI was reported in 33 cases. The patients were randomly divided into the training and validation cohorts. Significant variables from the training cohort were identified using univariate and multivariable analyses and were included in the model.</p><p><strong>Results: </strong>The analysis identified six potential variables associated with PPOI among the included participants. The incidence rate of PPOI was 27.5%. Age ≥ 70 years, cTNM stage (I and IV), preoperative hypoproteinemia, recovery time of bowel sounds (RTBS), number of bowel sounds (NBS), and frequency of bowel sounds (FBS) were independent risk factors for PPOI. The Bayesian model demonstrated good performance with internal validation: Training cohort [area under the curve (AUC) = 0.880, accuracy = 0.823, Brier score = 0.139] and validation cohort (AUC = 0.747, accuracy = 0.690, Brier score = 0.215). The model showed a good fit and calibration in the decision curve analysis, indicating a significant net benefit.</p><p><strong>Conclusion: </strong>PPOI is a common complication following gastrectomy in patients with GC and is associated with age, cTNM stage, preoperative hypoproteinemia, and specific bowel sound-related indices (RTBS, NBS, and FBS). To facilitate early intervention and improve patient outcomes, clinicians should consider these factors, optimize preoperative nutritional status, and implement routine postoperative bowel sound monitoring. This study introduces an accessible machine learning model for predicting PPOI in patients with GC.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"16 11","pages":"3484-3498"},"PeriodicalIF":1.8,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622100/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142795313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Benefits and drawbacks of radiofrequency ablation <i>via</i> percutaneous or minimally invasive surgery for treating hepatocellular carcinoma.","authors":"Ching-Lung Hsieh, Cheng-Ming Peng, Chun-Wen Chen, Chang-Hsien Liu, Chih-Tao Teng, Yi-Jui Liu","doi":"10.4240/wjgs.v16.i11.3400","DOIUrl":"10.4240/wjgs.v16.i11.3400","url":null,"abstract":"<p><p>The management of early stage hepatocellular carcinoma (HCC) presents significant challenges. While radiofrequency ablation (RFA) has shown safety and effectiveness in treating HCC, with lower mortality rates and shorter hospital stays, its high recurrence rate remains a significant impediment. Consequently, achieving improved survival solely through RFA is challenging, particularly in retrospective studies with inherent biases. Ultrasound is commonly used for guiding percutaneous RFA, but its low contrast can lead to missed tumors and the risk of HCC recurrence. To enhance the efficiency of ultrasound-guided percutaneous RFA, various techniques such as artificial ascites and contrast-enhanced ultrasound have been developed to facilitate complete tumor ablation. Minimally invasive surgery (MIS) offers advantages over open surgery and has gained traction in various surgical fields. Recent studies suggest that laparoscopic intraoperative RFA (IORFA) may be more effective than percutaneous RFA in terms of survival for HCC patients unsuitable for surgery, highlighting its significance. Therefore, combining MIS-IORFA with these enhanced percutaneous RFA techniques may hold greater significance for HCC treatment using the MIS-IORFA approach. This article reviews liver resection and RFA in HCC treatment, comparing their merits and proposing a trajectory involving their combination in future therapy.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"16 11","pages":"3400-3407"},"PeriodicalIF":1.8,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622093/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142795242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pembrolizumab in patients with gastric cancer and liver metastases: A paradigm shift in immunotherapy.","authors":"Grigorios Christodoulidis, Dimitra Bartzi, Konstantinos Eleftherios Koumarelas, Marina Nektaria Kouliou","doi":"10.4240/wjgs.v16.i11.3391","DOIUrl":"10.4240/wjgs.v16.i11.3391","url":null,"abstract":"<p><p>In this editorial, we explore the impact of immunotherapy and its safety in patients with advanced gastric cancer (GC) and liver involvement. GC, a formidable adversary in the oncology landscape, presents its most challenging battlefront when it reaches stage IV, often characterized by liver metastases. The prognosis for patients at this advanced stage is daunting, with systemic chemotherapy traditionally offering a median overall survival slightly over a year. However, the landscape of treatment is evolving, with new strategies and therapies offering a glimmer of hope.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"16 11","pages":"3391-3394"},"PeriodicalIF":1.8,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622097/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142795312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Blue rubber blister nevus syndrome: A case report.","authors":"Wen-Jing Wang, Pei-Li Chen, Huan-Zhang Shao","doi":"10.4240/wjgs.v16.i11.3584","DOIUrl":"10.4240/wjgs.v16.i11.3584","url":null,"abstract":"<p><strong>Background: </strong>Blue rubber blister nevus syndrome (BRBNS) is a congenital, rare disease characterized by venous malformations of the skin and internal organs, affecting all systems throughout the body. The pathogenesis is unknown. There is no consensus on the treatment of BRBNS. Most of the previously reported cases were mild to moderate with a good prognosis, and this case was a critically ill patient with severe gastrointestinal hemorrhage, disseminated intravascular coagulation (DIC), and severe joint fusion that was different from previously reported cases.</p><p><strong>Case summary: </strong>An 18-year-old man with early onset of BRBNS in early childhood is reported. He presented with recurrent melena and underwent malformed phlebectomy and partial jejunectomy and ileal resection. The patient had melena before and after surgery. After active treatment, the patient's gastrointestinal bleeding improved. This was a case of atypical BRBNS with severe gastrointestinal bleeding and severe joint fusion, which should be differentiated from other serious joint lesions and provide clinicians with better understanding of this rare disease.</p><p><strong>Conclusion: </strong>This case of critical BRBNS with gastrointestinal hemorrhage, DIC and severe joint fusion provides further understanding of this rare disease.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"16 11","pages":"3584-3589"},"PeriodicalIF":1.8,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622090/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142795245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Preoperative gastric retention in endoscopic retrograde cholangiopancreatography.","authors":"Alkiviadis Efthymiou, Patrick T Kennedy","doi":"10.4240/wjgs.v16.i11.3632","DOIUrl":"10.4240/wjgs.v16.i11.3632","url":null,"abstract":"<p><p>We comment on the article by Jia <i>et al</i>, in the <i>World Journal of Gastrointestinal Surgery</i>. We focus mainly on the factors that impair gastric motility and cause gastric retention in the pre-operative setting of endoscopic retrograde cholangiopancreatography (ERCP). ERCP is a complex endoscopic therapeutic procedure, which demands great skill from the endoscopist but also has recognized complications. Gastric retention impairs the endoscopist's visibility but also increases the risk of complications, such as aspiration pneumonia. Therefore, identifying the factors that predispose to gastric retention alerts the endoscopists of the possible risks and enables them to take evasive action. The authors in the current study by Jia <i>et al</i> developed and validated a predictive model, which incorporates five different factors, <i>i.e.</i>, gender, primary disease, jaundice, opioid use, and gastrointestinal obstruction, which were found to influence gastric retention. This model was shown to have a high predictive value to accurately identify patients at risk for gastric retention before a therapeutic ERCP.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"16 11","pages":"3632-3635"},"PeriodicalIF":1.8,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622087/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142795314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xiao-Bo Cheng, Li Yang, Ming-Qian Lu, Yi-Bo Peng, Lei Wang, Shuang-Ming Zhu, Zhi-Wei Hu, Zhong-Liang Wang, Qin Yang
{"title":"Clinical study of different interventional treatments for primary hepatocellular carcinoma based on propensity-score matching.","authors":"Xiao-Bo Cheng, Li Yang, Ming-Qian Lu, Yi-Bo Peng, Lei Wang, Shuang-Ming Zhu, Zhi-Wei Hu, Zhong-Liang Wang, Qin Yang","doi":"10.4240/wjgs.v16.i11.3463","DOIUrl":"10.4240/wjgs.v16.i11.3463","url":null,"abstract":"<p><strong>Background: </strong>Transcatheter arterial chemoembolization (TACE) is the main treatment for patients with primary hepatocellular carcinoma (PHC) who miss the opportunity to undergo surgery. Conventional TACE (c-TACE) uses iodized oil as an embolic agent, which is easily washed by blood and affects its efficacy. Drug-eluting bead TACE (DEB-TACE) can sustainably release chemotherapeutic drugs and has a long embolization time. However, the clinical characteristics of patients before the two types of interventional therapies may differ, possibly affecting the conclusion. Only a few studies have compared these two interventions using propensity-score matching (PSM).</p><p><strong>Aim: </strong>To analyze the clinical effects of DEB-TACE and c-TACE on patients with PHC based on PSM.</p><p><strong>Methods: </strong>Patients with PHC admitted to Dangyang People's Hospital (March 2020 to March 2024) were retrospectively enrolled and categorized into groups A (DEB-TACE, <i>n</i> = 125) and B (c-TACE, <i>n</i> = 106). Sex, age, Child-Pugh grade, tumor-node-metastasis stage, and Eastern Cooperative Oncology Group score were selected for 1:1 PSM. Eighty-six patients each were included post-matching. Clinical efficacy, liver function indices (aspartate aminotransferase, alanine aminotransferase, total bilirubin, and albumin), tumor serum markers, and adverse reactions were compared between the groups.</p><p><strong>Results: </strong>The objective response and disease control rates were significantly higher in group A (80.23% and 97.67%, respectively) than in group B (60.47% and 87.21%, respectively) (<i>P</i> < 0.05). Post-treatment levels of aspartate aminotransferase, alanine aminotransferase, and total bilirubin were lower in group A than in group B (<i>P</i> < 0.05), whereas post-treatment levels of albumin in group A were comparable to those in group B (<i>P</i> > 0.05). Post-treatment levels of tumor serum markers were significantly lower in group A than in group B (<i>P</i> < 0.05). Patients in groups A and B had mild-to-moderate fever and vomiting symptoms, which improved with conservative treatment. The total incidence of adverse reactions was significantly higher in group B (22.09%) than in group A (6.97%) (<i>P</i> < 0.05).</p><p><strong>Conclusion: </strong>DEB-TACE has obvious therapeutic effects on patients with PHC. It can improve liver function indices and tumor markers of patients without increasing the rate of liver toxicity or adverse reactions.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"16 11","pages":"3463-3470"},"PeriodicalIF":1.8,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622076/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142795249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Endoscopic ultrasound-guided biliary drainage <i>vs</i> percutaneous transhepatic biliary drainage for malignant biliary obstruction after endoscopic retrograde cholangiopancreatography failure.","authors":"He Zhao, Xiao-Wu Zhang, Peng Song, Xiao Li","doi":"10.4240/wjgs.v16.i11.3614","DOIUrl":"10.4240/wjgs.v16.i11.3614","url":null,"abstract":"<p><p>In a recent issue of the <i>World Journal of Gastrointestinal Surgery</i>, a meta-analysis investigated the safety and efficacy of electrocautery-enhanced lumen-apposing metal stent (ECE-LAMS) implantation for managing malignant biliary obstruction following failed endoscopic retrograde cholangiopancreatography. This manuscript endeavors to offer a comprehensive look at the progression of endoscopic ultrasound-guided biliary drainage (EUS-BD) technologies, weighing their merits and drawbacks against traditional percutaneous methods. Several meta-analyses and randomized controlled trials have compared the performance of EUS-BD and percutaneous transhepatic cholangiodrainage (PTCD). These studies revealed that the technical success rate, clinical success rate, and adverse events were similar between EUS-BD and PTCD. Nevertheless, given that most of these studies predate 2015, the safety and effectiveness of novel EUS-BD techniques, including ECE-LAMS, compared with those of percutaneous biliary drainage remain elusive. Further investigation is imperative to ascertain whether these novel EUS-BD techniques can safely and efficaciously replace conventional percutaneous therapeutic approaches.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"16 11","pages":"3614-3617"},"PeriodicalIF":1.8,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622083/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142795290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Immunotherapy for metastatic gastric cancer.","authors":"Chang-Fei Li, Li-Li Lian, Qiu-Ru Li, Yan Jiao","doi":"10.4240/wjgs.v16.i11.3408","DOIUrl":"10.4240/wjgs.v16.i11.3408","url":null,"abstract":"<p><p>This editorial discusses the article written by Chen <i>et al</i> that was published in the latest edition of the <i>World Journal of Gastrointestinal Surgery</i>. The current study found that programmed cell death 1 ligand 1 (PD-L1) expression is considered as one of the pan-cancer biomarkers of immune checkpoint inhibitors (ICIs) treatment response. Four molecular subtypes are widely used to guide and evaluate the prognosis and diagnosis and treatment of gastric cancer (GC) patients. Clinical trials of ICI treatment including Nivolumab, Pembrolizumab, Avelumab have been conducted for metastatic GC (mGC). The effects of various single agent ICIs on mGC therapy varied. ICIs combined with chemotherapy can indeed bring survival benefits to patients with mGC. Combining ICIs with chemotherapy can give more patients the chance of surgery in the treatment of GC transformation. However, not all PD-L1 positive patients can benefit from it. It is urgent to find better biomarkers to predict the response of ICIs for more precise clinical treatment.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"16 11","pages":"3408-3412"},"PeriodicalIF":1.8,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622096/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142795297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fang-Nan Wu, Min Zhang, Kun Zhang, Xin-Liang Lv, Jing-Qiang Guo, Chao-Yong Tu, Qing-Yun Zhou
{"title":"Primary hepatic leiomyosarcoma masquerading as liver abscess: A case report.","authors":"Fang-Nan Wu, Min Zhang, Kun Zhang, Xin-Liang Lv, Jing-Qiang Guo, Chao-Yong Tu, Qing-Yun Zhou","doi":"10.4240/wjgs.v16.i11.3598","DOIUrl":"10.4240/wjgs.v16.i11.3598","url":null,"abstract":"<p><strong>Background: </strong>Primary hepatic leiomyosarcoma (PHL) is a rare malignant tumor and has non-specific clinical manifestations and imaging characteristics, making preoperative diagnosis challenging. Here, we report a case of PHL presenting primarily with fever, with computed tomography imaging showing a thick-walled hepatic lesion with low-density areas, resembling liver abscess.</p><p><strong>Case summary: </strong>The patient was a 34-year-old woman who presented with right upper abdominal pain and fever over 4 days before admission. Based on the patient's medical history, laboratory examinations, and imaging examinations, liver abscess was suspected. Mesenchymal tumor was diagnosed by percutaneous liverbiopsy and partial hepatectomy was performed. Postoperative pathology revealed PHL. The patient is currently undergoing intravenous chemotherapy with the AD regimen and shows no signs of recurrence.</p><p><strong>Conclusion: </strong>When there is a thick wall and rich blood supply in the hepatic lesion with a large proportion of uneven low-density areas, PHL should be considered.</p>","PeriodicalId":23759,"journal":{"name":"World Journal of Gastrointestinal Surgery","volume":"16 11","pages":"3598-3605"},"PeriodicalIF":1.8,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622095/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142795134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}