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Relationship between selenium and hematologic markers in overweight and anemic patients 超重和贫血患者体内硒与血液学指标的关系
Vrach Pub Date : 2024-01-31 DOI: 10.29296/25877305-2024-01-09
М. Khabibulina, О. Bazhenova, М. Shamilov
{"title":"Relationship between selenium and hematologic markers \u0000in overweight and anemic patients","authors":"М. Khabibulina, О. Bazhenova, М. Shamilov","doi":"10.29296/25877305-2024-01-09","DOIUrl":"https://doi.org/10.29296/25877305-2024-01-09","url":null,"abstract":"Anemia is a widespread polyethological disease, one of the possible causes of which is chronic inflammation. In addition, selenium deficiency is also often detected in patients with anemia. In the study, we studied the effect of selenium on iron status in young men with anemia and overweight (since obesity is often associated with chronic inflammation) and the expediency of its use in real clinical practice. \u0000The obtained results of treatment of two groups of patients with anemia and overweight who received iron monotherapy and combined therapy with iron and selenium showed that biomarkers of iron status significantly improved with combined treatment with SELENBIO for women than with iron monotherapy (p<0.05). \u0000The drug SELENBIO for women has a complex and versatile effect on the human body, has a restorative, immunomodulatory effect, and slows down the aging process due to its antioxidant effect at the cellular level. All components of the drug are physiologically close to the human body and do not disrupt the natural processes occurring in it. The drug SELENBIO for women is highly effective with low toxicity, has a wide range of effects, has a complex harmonizing effect on the body.","PeriodicalId":23748,"journal":{"name":"Vrach","volume":"290 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140472059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Features of vegetative adaptation to educational activities of primary school children 小学生对教育活动的植物适应特点
Vrach Pub Date : 2024-01-31 DOI: 10.29296/25877305-2024-01-13
А. Lebedenko, I. Ershova, A. Levchin, А. Rogovtsova
{"title":"Features of vegetative adaptation to educational activities of primary school children","authors":"А. Lebedenko, I. Ershova, A. Levchin, А. Rogovtsova","doi":"10.29296/25877305-2024-01-13","DOIUrl":"https://doi.org/10.29296/25877305-2024-01-13","url":null,"abstract":"Purpose. To study the functional state of the autonomic nervous system (ANS), which is involved in the formation of adaptation processes in schoolchildren with different physiological abilities.\u0000Material and methods. Three groups of junior schoolchildren were examined: 1st – intellectually gifted children, selected based on the results of specialized scales and tests; 2nd – children with high sports/physical abilities; 3rd (control) – schoolchildren with good academic performance and sports/physical abilities. The functional state of the ANS of children was studied using cardiointervalography.\u0000Results. The dynamics of the mode indicators, mode amplitude, variation range, and tension index of regulatory systems (IN) indicated that in group 1 the activity of the sympathetic influences of the ANS predominated, the ratio IN2/IN1 showed hypersympathicotonic reactivity. In group 2, the IN values corresponded to normotonic values. The majority of children in groups 2 and 3 had a normal type of autonomic response. The greatest increase in heart rate and systolic blood pressure during orthostasis was observed in group 1.\u0000Conclusion. Multidirectional changes in systolic blood pressure and an increase in diastolic blood pressure of varying degrees of severity were established in children of the study groups, which indicates the heterogeneous nature of vascular reactions to orthostasis. The rhythmogram indicators in group 1 are characterized by the predominance of the activity of the sympathetic influences of the ANS. The identified imbalance in the functional activity of the ANS in children of the 1st group indicates the tension of adaptation processes.","PeriodicalId":23748,"journal":{"name":"Vrach","volume":"64 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140478376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A comparative study of lappaconitine hydrobromide extended release and propafenone in patients with paroxysmal atrial fibrillation 阵发性心房颤动患者服用氢溴酸拉帕康尼汀缓释剂和普罗帕酮的比较研究
Vrach Pub Date : 2024-01-31 DOI: 10.29296/25877305-2024-01-04
А. Revishvili, S. Golitsyn, S. Aksentiev, А. Amiraslanov, А. Artyukhina, D. Duplyakov, Е. Zubov, Е. Isaeva, А. Loginova, Т. Malkina, G. Miloserdov, А. Rivin, S. Teplykh, I. Tsygankova, Yu. Shvarts, Y. Yuricheva, S. Kanorsky, S. Sokolov
{"title":"A comparative study of lappaconitine hydrobromide extended release and propafenone in patients with paroxysmal atrial fibrillation","authors":"А. Revishvili, S. Golitsyn, S. Aksentiev, А. Amiraslanov, А. Artyukhina, D. Duplyakov, Е. Zubov, Е. Isaeva, А. Loginova, Т. Malkina, G. Miloserdov, А. Rivin, S. Teplykh, I. Tsygankova, Yu. Shvarts, Y. Yuricheva, S. Kanorsky, S. Sokolov","doi":"10.29296/25877305-2024-01-04","DOIUrl":"https://doi.org/10.29296/25877305-2024-01-04","url":null,"abstract":"A new dosage form of lappaconitine hydrobromide has been created – the long-acting drug Allaforte®, which has fewer side effects compared to the traditional dosage form (Allapinin®).\u0000Objective. To evaluate the effectiveness, safety and tolerability of Allaforte® therapy in comparison with the drug Rytmonorm® in patients with paroxysmal atrial fibrillation (AF).\u0000Material and methods. Patients who met the inclusion criteria and those who did not meet the non-inclusion criteria were randomized into 2 groups: 1st (n=50) – \u0000patients received Allaforte® 25 mg 3 times a day with an increase in dose to \u000050 mg 2 times a day when detected attack of AF; 2nd (n=50) – patients received Rytmonorm® 150 mg 3 times a day with an increase in dose to 300 mg 2 times a day if an attack of AF was detected.\u0000Results. The average time from the first dose of the drug to the development of AF paroxysm in the 1st group (Allaforte®) was 98.877±6.022 days, in the 2nd group (Rytmonorm®) – 98.808±5.876 days, the average time from the first dose of the drug to the completion of the study – 105.740±5.032 and 103.732±5.353 days, respectively. The drugs Allaforte® and Rytmonorm® equally improved the quality of life of patients. A comparative analysis in groups according to the severity of adverse events and their cause-and-effect relationship with the drug did not show significant differences.\u0000Conclusion. The study drugs showed comparable effectiveness in preventing attacks of AF with similar safety and tolerability.","PeriodicalId":23748,"journal":{"name":"Vrach","volume":"52 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140476775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Asthma and pregnancy 哮喘与怀孕
Vrach Pub Date : 2024-01-31 DOI: 10.29296/25877305-2024-01-01
Author Sarah, M. M. E. S. M. Lyon, MD Kassutto, MD Hetal Patel, MD MEd Laura Hinkle, MD May M. Lee, MD Wei Jung Hisa, David J. De, MD La Zerda
{"title":"Asthma and pregnancy","authors":"Author Sarah, M. M. E. S. M. Lyon, MD Kassutto, MD Hetal Patel, MD MEd Laura Hinkle, MD May M. Lee, MD Wei Jung Hisa, David J. De, MD La Zerda","doi":"10.29296/25877305-2024-01-01","DOIUrl":"https://doi.org/10.29296/25877305-2024-01-01","url":null,"abstract":"Features of the course and treatment of bronchial asthma during pregnancy have been the subject of close attention of researchers in recent decades. Physiological changes and the nature of treatment of bronchial asthma during pregnancy determine the degree of control of the disease, which, in turn, affects the incidence of complications of pregnancy and childbirth, and the health of the newborn. The presented literature review analyzes recent publications on this issue.","PeriodicalId":23748,"journal":{"name":"Vrach","volume":"393 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140473067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Results of comparative analysis of health literacy among student youth of Aktobe city (Kazakhstan) 阿克托别市(哈萨克斯坦)青年学生健康知识比较分析结果
Vrach Pub Date : 2024-01-31 DOI: 10.29296/25877305-2024-01-16
G. Berdesheva, Е. Khairullina, А. Zhubaniyazova, К. Amlaev
{"title":"Results of comparative analysis of health literacy \u0000among student youth of Aktobe city (Kazakhstan)","authors":"G. Berdesheva, Е. Khairullina, А. Zhubaniyazova, К. Amlaev","doi":"10.29296/25877305-2024-01-16","DOIUrl":"https://doi.org/10.29296/25877305-2024-01-16","url":null,"abstract":"The level of health literacy (HL) has a significant impact on human health and quality of life. \u0000Objective. To conduct a comparative analysis of the level of student health education, depending on the specialty and the course of study. To test the European questionnaire to determine the level of HL, adapted for Kazakhstan.\u0000Materials and methods. In a single-stage cross-sectional study, 1st and 4th year students of the specialties «general medicine» (n=422) and «military medicine» (n=433) were interviewed.\u0000Results. Differences in the level of HL of all respondents in different fields were revealed. Proposals have been developed to increase the level of water supply.","PeriodicalId":23748,"journal":{"name":"Vrach","volume":"206 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140472763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sulodexide in clinical practice: possibilities and prospects of its use 舒洛地特在临床实践中的应用:应用的可能性和前景
Vrach Pub Date : 2024-01-31 DOI: 10.29296/25877305-2024-01-11
А. Morozov, А. Sergeev, А. Boltik, А. Aslakhanova, К. Ispieva
{"title":"Sulodexide in clinical practice: possibilities and prospects of its use","authors":"А. Morozov, А. Sergeev, А. Boltik, А. Aslakhanova, К. Ispieva","doi":"10.29296/25877305-2024-01-11","DOIUrl":"https://doi.org/10.29296/25877305-2024-01-11","url":null,"abstract":"Objective: to analyze up-to-date information about the efficiency of using sulodexide n clinical practice. Current publication on the efficacy and safety of sulodexide, as well as information on the pathogenesis and clinical manifestations of chronic venous insufficiency, microvascular angina, venous thromboembolic events, and diabetes mellitus have been sought for and analyzed Most clinical trials show that sulodexide exerts anti-inflammatory, endothelium-protective, and pleotrophic effects, by confirming its potential efficacy in the treatment of cardiovascular diseases, in particular chronic vein diseases, microvascular anginas, and venous thromboembolic events. Sulodexide as an additional therapy is used to treat type 2 diabetes mellitus.","PeriodicalId":23748,"journal":{"name":"Vrach","volume":"3 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140474207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prospects of application of non-hormonal drug Femo-Klim in complex therapy of menopausal disorders of medium severity in patients with cancer in anamnesis 非激素类药物 Femo-Klim 在癌症病人中等程度更年期紊乱综合疗法中的应用前景
Vrach Pub Date : 2024-01-31 DOI: 10.29296/25877305-2024-01-05
О. Vinogradova, О. Biryuchkova, S. Mikheeva
{"title":"Prospects of application of non-hormonal drug Femo-Klim in complex therapy of menopausal disorders of medium severity in patients with cancer in anamnesis","authors":"О. Vinogradova, О. Biryuchkova, S. Mikheeva","doi":"10.29296/25877305-2024-01-05","DOIUrl":"https://doi.org/10.29296/25877305-2024-01-05","url":null,"abstract":"Objective. To study the possibility of using Femo-Klim preparation in the treatment of menopausal disorders of medium severity in gynecologic oncologic patients.\u0000Material and methods. Seventy-eight female patients with menopausal syndrome of moderate severity participated in the study. The patients were randomly divided into 2 groups: the main group (n=40) – patients received Femo-Klim preparation; the comparison group (n=38) – patients did not receive the examined preparation.\u0000Results. After 6 months of the study the dynamics of menopausal manifestations in the main group amounted to -0.9, in the comparison group – -0.7, somatic manifestations – -0.55 and -0.15 respectively, psychoemotional manifestations – \u0000-0.8 and -0.5 respectively (p<0.05). The level of anxiety in the main group decreased by 60% compared to the comparison group. Bone mineral density increased by 2.6% in the main group and decreased by 1.4% in the comparison group (p<0.05).","PeriodicalId":23748,"journal":{"name":"Vrach","volume":"51 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140478180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Structured programs for the management of patients with non-alcoholic fatty liver disease in the work of a general practitioner 全科医生对非酒精性脂肪性肝病患者的结构化管理方案
Vrach Pub Date : 2023-03-06 DOI: 10.29296/25877305-2022-05-02
V. Skvortsov, M. Ustinova
{"title":"Structured programs for the management of patients with non-alcoholic fatty liver disease in the work of a general practitioner","authors":"V. Skvortsov, M. Ustinova","doi":"10.29296/25877305-2022-05-02","DOIUrl":"https://doi.org/10.29296/25877305-2022-05-02","url":null,"abstract":"Non — alcoholic steatohepatitis is a syndrome that develops in patients who do not abuse alcohol, while the nature of liver damage is histologically indistinguishable from alcoholic hepatitis. The condition occurs as a result of excessive accumulation of fats (triglycerides) in the liver, determined by the results of instrumental research methods or histology. Currently, non — alcoholic steatohepatitis (non-alcoholic fatty liver disease, NAFLD) is the most common chronic disease of the biliary system in developed countries and affects from 25 to 30 % of the adult population. The total prevalence in the world is 25.24 %. In the Russian Federation, according to recent studies, NAFLD was approximately 38.3 % in outpatient patients. NAFLD is closely associated with obesity, especially abdominal, which significantly increases cardiometabolic risk and affects morbidity, life expectancy and prognosis of patients. In obese patients, the prevalence of various forms of non-alcoholic fatty liver disease is significantly higher than in non-obese individuals.","PeriodicalId":23748,"journal":{"name":"Vrach","volume":"53 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88776844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Principles of diagnosis and treatment of primary extramedullary spinal cord tumors 原发性脊髓髓外肿瘤的诊治原则
Vrach Pub Date : 2022-01-01 DOI: 10.29296/25877305-2022-11-05
A. Yarikov, A. Dubskikh, I. Smirnov, A. Fraerman, O. Perlmutter, S. Tsybusov, A. Kalinkin, A. Simonov, A. Istrelov, S. Pavlinov
{"title":"Principles of diagnosis and treatment of primary extramedullary spinal cord tumors","authors":"A. Yarikov, A. Dubskikh, I. Smirnov, A. Fraerman, O. Perlmutter, S. Tsybusov, A. Kalinkin, A. Simonov, A. Istrelov, S. Pavlinov","doi":"10.29296/25877305-2022-11-05","DOIUrl":"https://doi.org/10.29296/25877305-2022-11-05","url":null,"abstract":"","PeriodicalId":23748,"journal":{"name":"Vrach","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74659007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The attitude of young people to smoking electronic cigarettes. Pharmacotherapy of nicotine addiction 年轻人对吸电子烟的态度。尼古丁成瘾的药物治疗
Vrach Pub Date : 2022-01-01 DOI: 10.29296/25877305-2022-02-04
T. Potupchik, L. Evert, Y. Kostyuchenko, A. Ilyashevlch, M. Tkach
{"title":"The attitude of young people to smoking electronic cigarettes. Pharmacotherapy of nicotine addiction","authors":"T. Potupchik, L. Evert, Y. Kostyuchenko, A. Ilyashevlch, M. Tkach","doi":"10.29296/25877305-2022-02-04","DOIUrl":"https://doi.org/10.29296/25877305-2022-02-04","url":null,"abstract":"","PeriodicalId":23748,"journal":{"name":"Vrach","volume":"125 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74659325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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