全科医生对非酒精性脂肪性肝病患者的结构化管理方案

Vrach Pub Date : 2023-03-06 DOI:10.29296/25877305-2022-05-02
V. Skvortsov, M. Ustinova
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引用次数: 0

摘要

非酒精性脂肪性肝炎是一种发生在不滥用酒精的患者身上的综合征,而肝损伤的性质在组织学上与酒精性肝炎难以区分。这种情况的发生是由于肝脏中脂肪(甘油三酯)的过度积累,由仪器研究方法或组织学的结果决定。目前,非酒精性脂肪性肝炎(非酒精性脂肪性肝病,NAFLD)是发达国家最常见的胆道系统慢性疾病,影响了25%至30%的成年人口。全球总患病率为25.24%。在俄罗斯联邦,根据最近的研究,NAFLD在门诊患者中约占38.3%。NAFLD与肥胖,特别是腹部肥胖密切相关,显著增加心脏代谢风险,影响患者的发病率、预期寿命和预后。在肥胖患者中,各种形式的非酒精性脂肪性肝病的患病率明显高于非肥胖者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Structured programs for the management of patients with non-alcoholic fatty liver disease in the work of a general practitioner
Non — alcoholic steatohepatitis is a syndrome that develops in patients who do not abuse alcohol, while the nature of liver damage is histologically indistinguishable from alcoholic hepatitis. The condition occurs as a result of excessive accumulation of fats (triglycerides) in the liver, determined by the results of instrumental research methods or histology. Currently, non — alcoholic steatohepatitis (non-alcoholic fatty liver disease, NAFLD) is the most common chronic disease of the biliary system in developed countries and affects from 25 to 30 % of the adult population. The total prevalence in the world is 25.24 %. In the Russian Federation, according to recent studies, NAFLD was approximately 38.3 % in outpatient patients. NAFLD is closely associated with obesity, especially abdominal, which significantly increases cardiometabolic risk and affects morbidity, life expectancy and prognosis of patients. In obese patients, the prevalence of various forms of non-alcoholic fatty liver disease is significantly higher than in non-obese individuals.
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