World Journal of Nuclear Medicine最新文献

{"title":"Rare Isolated Cerebellar Metastases in Prostate Cancer: A Case Report with Review of Literature.","authors":"Nimmagadda Ajit,&nbsp;Gadepalli Tejonath,&nbsp;Bikkina Pratyusha,&nbsp;Abubacker Ali Zakir","doi":"10.1055/s-0043-1768449","DOIUrl":"https://doi.org/10.1055/s-0043-1768449","url":null,"abstract":"<p><p>Prostate cancer is a common malignancy affecting elderly males. Generally, prostate cancer metastases to lymph nodes and skeletal lesions. Brain metastasis from prostate cancer is an uncommon phenomenon. When occurs, it affects the liver and lungs. Less than 1% of the cases show brain metastases, with isolated brain metastases being even more rare. We present the case of a 67-year-old male patient who was diagnosed to have prostate carcinoma and maintained on hormonal therapy. Later, the patient presented with raising serum-68 prostate-specific antigen (PSA) levels. Gallium-68 prostate-specific membrane antigen (PSMA) positron emission tomography (PET)/computed tomography (CT) scan revealed isolated cerebellar metastasis. He was later treated with whole brain radiotherapy.</p>","PeriodicalId":23742,"journal":{"name":"World Journal of Nuclear Medicine","volume":"22 2","pages":"140-143"},"PeriodicalIF":0.6,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202584/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9569999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sellar-Parasellar and Petrous Bone Metastasis from Differentiated Thyroid Carcinoma: Imaging Characteristics and Follow-Up Profile Post Radioiodine Therapy.","authors":"Sunita Nitin Sonavane,&nbsp;Trupti Upadhye,&nbsp;Sandip Basu","doi":"10.1055/s-0043-1768664","DOIUrl":"https://doi.org/10.1055/s-0043-1768664","url":null,"abstract":"<p><p>Sella turcica and petrous bone metastasis from differentiated thyroid carcinoma are rare clinical entities, with only a few limited cases reported to date. Two cases, one of sella turcica metastasis and the other of petrous bone metastasis from carcinoma of the thyroid gland, are presented. The cases diagnosed to have arisen from poorly differentiated thyroid carcinoma and follicular carcinoma of thyroid, respectively, subsequently underwent total thyroidectomy, radioiodine (RAI) scans and RAI therapies with iodine-131, external radiotherapy, and levothyroxine suppression with follow-up. Their clinical symptoms gradually subsided, with reduction in serum thyroglobulin, and finally resulted in disease stabilization. With the multimodality therapeutic approach, both patients are alive to date, with 48- and 60-month survival post diagnosis, respectively.</p>","PeriodicalId":23742,"journal":{"name":"World Journal of Nuclear Medicine","volume":"22 2","pages":"144-149"},"PeriodicalIF":0.6,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202566/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9871528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Region-of-Interest Delineation on Stability and Reproducibility of Liver SNR Measurements in ⁶⁸ Ga-PSMA PET/CT.","authors":"Masoomeh Fooladi,&nbsp;Sahar Rezaei,&nbsp;Farahnaz Aghahosseini,&nbsp;Yalda Salehi,&nbsp;Nima Kasraie,&nbsp;Peyman Sheikhzadeh","doi":"10.1055/s-0043-1768446","DOIUrl":"https://doi.org/10.1055/s-0043-1768446","url":null,"abstract":"<p><p><b>Objective</b>  This study aims to assess the impact of various regions of interest (ROIs) and volumes of interest (VOIs) delineations on the reproducibility of liver signal-to-noise-ratio (SNRliver) measurements, as well as to find the most reproducible way to estimate it in gallium-68 positron emission tomography ( ⁶⁸ Ga-PET) imaging. We also investigated the SNRliver-weight relationship for these ROIs and VOIs delineations. <b>Methods</b>  A cohort of 40 patients (40 males; mean weight: 76.5 kg [58-115 kg]) with prostate cancer were included. ⁶⁸ Ga-PET/CT imaging (mean injected activity: 91.4 MBq [51.2 MBq to 134.1 MBq] was performed on a 5-ring bismuth germanium oxide-based Discovery IQ PET/CT using ordered subset expectation maximization image reconstruction algorithm. Afterward, circular ROIs and spherical VOIs with two different diameters of 30 and 40 mm were drawn on the right lobe of the livers. The performance of the various defined regions was evaluated by the average standardized uptake value (SUV _mean ), standard deviation (SD) of the SUV (SUV _SD ), SNR _liver , and SD of the SNR _liver metrics. <b>Results</b>  There were no significant differences in SUV _mean among the various ROIs and VOIs ( <i>p</i>  > 0.05). On the other hand, the lower SUV _SD was obtained by spherical VOI with diameter of 30 mm. The largest SNR _liver was obtained by ROI (30 mm). The SD of SNR _liver with ROI (30 mm) was also the largest, while the lowest SD of SNR _liver was observed for VOI (40 mm). There is a higher correlation coefficient between the patient-dependent parameter of weight and the image quality parameter of SNRliver for both VOI (30 mm) and VOI (40 mm) compared to the ROIs. <b>Conclusion</b>  Our results indicate that SNR _liver measurements are affected by the size and shape of the respective ROIs and VOIs. The spherical VOI with a 40 mm diameter leads to more stable and reproducible SNR measurement in the liver.</p>","PeriodicalId":23742,"journal":{"name":"World Journal of Nuclear Medicine","volume":"22 2","pages":"124-129"},"PeriodicalIF":0.6,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202577/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9888126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lesion Analysis in PERCIST 1.0: Clinical Ease versus Research Requisite-Where Does the Balance Exist?","authors":"Amit Bhoil","doi":"10.1055/s-0042-1750406","DOIUrl":"https://doi.org/10.1055/s-0042-1750406","url":null,"abstract":"<p><p><b>Background</b>  Semiqualitative parameter SUVmax has been the most frequently used semiquantitative positron emission tomography (PET) parameter for response evaluation, but only metabolic activity of a single (most metabolic) lesion is predicted. Newer response parameters such as tumor lesion glycolysis (TLG) incorporating lesions' metabolic volume or whole-body metabolic tumor burden (MTBwb) are being explored for response evaluation. Evaluation and comparison of response with different semiquantitative PET parameters such as SUVmax and TLG in most metabolic lesion, multiple lesions (max of five), and MTBwb in advanced non-small cell lung cancer (NSCLC) patients were made. The different PET parameters were analyzed for response evaluation, overall survival (OS), and progression-free survival (PFS). <b>Methods</b>   ¹⁸ F-FDG-PET/CT (18-fluorine-fluorodeoxyglucose positron emission tomography/computed tomography) imaging was performed in 23 patients (M = 14, F = 9, mean age = 57.6 years) with stage IIIB-IV advanced NSCLC before initiation of therapy with oral estimated glomerular filtration rate-tyrosine kinase inhibitor for early and late response evaluation. The quantitative PET parameters such as SUVmax and TLG were measured in single (most metabolic) lesion, multiple lesions, and MTBwb. The parameters SUVmax, TLG, and MTBwb were compared for early and late response evaluation and analyzed for OS and PFS <b>Results</b>  No significant difference in change in response evaluation was seen in patients evaluated with most metabolic lesion, multiple lesions, or MTBwb. Difference in early (DC 22, NDC 1) and late (DC 20, NDC 3) response evaluation was seen that remained unchanged when lesions were measured in terms of number of lesions or the MTBwb. The early imaging was seen to be statistically significant to the OS compared with late imaging. <b>Conclusions</b>  Single (most metabolic) lesion shows similar disease response and OS to multiple lesions and MTBwb. Response evaluation by late imaging offered no significant advantage compared with early imaging. Thus, early response evaluation with SUVmax parameter offers a good balance between clinical ease and research requisition.</p>","PeriodicalId":23742,"journal":{"name":"World Journal of Nuclear Medicine","volume":"22 2","pages":"100-107"},"PeriodicalIF":0.6,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202569/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9570002","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Post-Topotecan Mixed Response and 'Redifferentiation-akin' Phenomenon on Dual Tracer PET-CT in Multiple Treatment-Resistant Metastatic Neuroendocrine Neoplasm.","authors":"Sarvesh Loharkar,&nbsp;Sandip Basu","doi":"10.1055/s-0043-1760761","DOIUrl":"https://doi.org/10.1055/s-0043-1760761","url":null,"abstract":"<p><p>A 50-year-old female patient of heavily pre-treated (chemotherapy and multiple treatment-resistant) and progressive intermediate-grade metastatic neuroendocrine neoplasm is presented, wherein the lesions showed mixed response following topotecan treatment and multiple hepatic metastasis showed increase in the SSTR expression and decrease in FDG concentration on dual-tracer PET/CT ( ⁶⁸ Ga-DOTATATE and ¹⁸ F-FDG PET/CT). Such observation allowed ¹⁷⁷ Lu-DOTATATE PRRT to be considered for an advanced, symptomatic, and multiple treatment-resistant patient with limited palliative treatment options left.</p>","PeriodicalId":23742,"journal":{"name":"World Journal of Nuclear Medicine","volume":"22 2","pages":"130-134"},"PeriodicalIF":0.6,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202582/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9518982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of Pulmonary Metastasis in Differentiated Thyroid Carcinoma: Value of HRCT Correlation with Functional Imaging.","authors":"Ashwini Kalshetty,&nbsp;Sandip Basu","doi":"10.1055/s-0043-1764307","DOIUrl":"https://doi.org/10.1055/s-0043-1764307","url":null,"abstract":"<p><p>Pulmonary metastases in thyroid carcinoma demonstrates varying imaging characteristics and disease biology and the outcome. The valuable complimentary role of high-resolution CT (HRCT) in conjunction with functional imaging such as radioiodine scan has been discussed and illustrated in this review along with the varied clinical and imaging presentations of lung metastases from differentiated thyroid cancer (DTC). A multi-modality patient-specific diagnostic approach and awareness about the atypical presentations helps in early identification as well as effective management of these patients, and especially in certain situations that could need multi-disciplinary management. While HRCT of the lungs as an added tool provides detailed visualization of the lung parenchyma, in the era of hybrid imaging, the routine adoption of SPECT-CT in patients with pulmonary metastases (in diagnostic or post-treatment settings) could provide equivalent or even incremental information from further management viewpoint.</p>","PeriodicalId":23742,"journal":{"name":"World Journal of Nuclear Medicine","volume":"22 2","pages":"87-99"},"PeriodicalIF":0.6,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10278235/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9764043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nuclear Medicine Training: Skills and Competencies Required for Practice in the 21st Century.","authors":"Ismaheel O Lawal","doi":"10.1055/s-0043-1769588","DOIUrl":"https://doi.org/10.1055/s-0043-1769588","url":null,"abstract":"Nuclear medicine (NM) utilizes unsealed radiation sources to diagnose and treat diseases. In the NM team, the NM physician works in collaboration with many other NM professionals who play critical roles in care delivery to patients. The NM team, therefore, consists of the NM physicians, the radiochemists, the medical physicists, and NM technologists, and others. Each of these groups in the NM team has made signi fi cant contributions to the fi eld of NM, resulting in amazing growth over thelast two decades or so. 1 Thisgrowth with implications for a promising feature for NM has been in the form of improvement in instrumentation, advances in radiopharmaceutical synthesis, the introduction of novel diagnostic and therapeutic radiopharmaceuticals, optimiza-tion of dosimetry methods, and, consequently, broadening of the applications of NM techniques in the clinics. While this growth occurring in all aspects of the fi eld has made the future of the profession exciting, it has also come with a need for residency training to evolve to produce NM physicians with the requisite skill sets and competencies that make them suitable to deliver ef fi cient care in the 21st century. In this editorial, I will focus on the emerging skill sets and competencies that NM trainees need to acquire in their residency training to render fi t-for-purpose diagnostic and therapeutic NM care in the 21st century.","PeriodicalId":23742,"journal":{"name":"World Journal of Nuclear Medicine","volume":"22 2","pages":"75-77"},"PeriodicalIF":0.6,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202562/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9871529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic Role of Diastolic Left Ventricular Mechanical Dyssynchrony by Gated Single Photon Emission Computed Tomography Myocardial Perfusion Imaging in Post-Myocardial Infarction.","authors":"Le Ngoc Ha,&nbsp;Nguyen Thi Thanh Trung,&nbsp;Mai Hong Son,&nbsp;Do Van Chien,&nbsp;Jin Chun Paeng","doi":"10.1055/s-0043-1764304","DOIUrl":"https://doi.org/10.1055/s-0043-1764304","url":null,"abstract":"<p><p><b>Objective</b>  This study is aimed to assess the prognostic value of diastolic left ventricular mechanical dyssynchrony (LVMD) measured by gated-single photon emission computed tomography (GSPECT) myocardial perfusion imaging (MPI) in post-myocardial infarction (MI). <b>Subjects and Methods</b>  The study was conducted on 106 post-MI from January 2015 to January 2019. First, the indices of diastolic LVMD phase standard deviation (PSD) and histogram bandwidth (HBW) of post-MI were measured using the Cardiac Emory Toolbox. Subsequently, the post-MI patients were followed up, and the primary endpoint was major adverse cardiac events (MACEs). Finally, the prognostic value of dyssynchrony parameters for MACE was analyzed by the receiver-operating characteristics curve and survival analyses. <b>Results</b>  With the cut-off values of 55.5 degrees of PSD, the sensitivity and specificity in prediction of MACE were 75% and 80.8%, with the cut-off values of 174.5 degrees of HBW, the sensitivity and specificity were 75% and 83.3% respectively. There was a significant difference of time to MACE between groups of PSD less than 55.5 degrees and more than 55.5 degrees. PSD, HBW, and left ventricle ejection fraction (LVEF) assessed on GSPECT were significant factors in the prediction of MACE. <b>Conclusion</b>  Diastolic LVMD parameters of PSD and HBW derived from GSPECT are significant prognostic factors in predicting MACE in post-MI patients.</p>","PeriodicalId":23742,"journal":{"name":"World Journal of Nuclear Medicine","volume":"22 2","pages":"108-113"},"PeriodicalIF":0.6,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202567/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9871532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"¹⁸⁸ Re-N-DEDC Lipiodol for Treatment of Hepatocellular Carcinoma (HCC)-A Clinical and Prospective Study to Assess In-Vivo Distribution in Patients and Clinical Feasibility of Therapy.","authors":"Naresh Kumar,&nbsp;Priyanka Gupta,&nbsp;Shamim Ahmed Shamim,&nbsp;Viju Chirayil,&nbsp;Suresh Subramanian,&nbsp;Madhava B Mallia,&nbsp;Chandrasekhar Bal","doi":"10.1055/s-0043-1764306","DOIUrl":"https://doi.org/10.1055/s-0043-1764306","url":null,"abstract":"<p><p><b>Objective</b>  The incidence of inoperable hepatocellular carcinoma (HCC) with/without malignant portal vein thrombosis (PVT) is increasing in India for the last decade; thus, Bhabha Atomic Research Centre (BARC), Mumbai, India, developed diethydithiocarbamate (DEDC), a new transarterial radionuclide therapy (TART) agent. ¹⁸⁸ Re-N-DEDC lipiodol is an emerging radiotherapeutic agent for inoperable HCC treatment due to its simple and onsite labeling procedure, cost-effectiveness, and least radiation-induced side effects. This study aimed to evaluate in-vivo biodistribution and clinical feasibility of ¹⁸⁸ Re-N-DEDC lipiodol TART in HCC and optimization of labeling procedure to assess post-labeling stability and radiochemical yield of labeled lipiodol with ¹⁸⁸ Re-N-DEDC complex. <b>Materials and Methods</b>  DEDC kits were obtained as gift from BARC, Mumbai. Therapy was given to 31 HCC patients. Post-therapy planar and single-photon emission computed tomography/computed tomography (SPECT/CT) imaging were performed to see tumor uptake and biodistribution. Clinical feasibility and toxicity were decided by Common Terminology Criteria for Adverse Events version 5.0 (CTCAE v 5.0). <b>Statistical Analysis</b>  Descriptive statistics was done for data using SPSS v22. Values was expressed as mean ± standard deviation or median with range. <b>Results</b>  Post-therapy planar and SPECT/CT imaging showed radiotracer localization in hepatic lesions. Few patients showed lungs uptake due to hepato-pulmonary shunt (lung shunt < 10%). Maximum clearance was observed through urinary tract with very less elimination through hepatobiliary route due to slow rate of leaching of tracer. No patient showed myelosuppression or any other long-term toxicity over median follow-up of 6 months. Mean overall % radiochemical yield of ¹⁸⁸ Re-N-DEDC lipiodol was 86.04 ± 2.35%. The complex ¹⁸⁸ Re-N-DEDC was found to be stable at 37°C under sterile condition over a period of 1 hour without any significant change on the % radiochemical purity (90.83 ± 3.24%, 89.78 ± 3.67%, 89.22 ± 3.77% at 0, 0.5, 1 hours, respectively). <b>Conclusion</b>  Human biodistribution showed very high retention of radiotracer in hepatic lesions with no long-term toxicity with this therapy. The kit preparation procedure is ideally suited for a busy hospital radio-pharmacy. By this procedure, ¹⁸⁸ Re-N-DEDC lipiodol can be prepared in high radiochemical yield within a short time (∼45 minutes). Thus, ¹⁸⁸ Re-N-DEDC lipiodol can be considered for TART in advanced and/or intermediate HCC.</p>","PeriodicalId":23742,"journal":{"name":"World Journal of Nuclear Medicine","volume":"22 2","pages":"114-123"},"PeriodicalIF":0.6,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202571/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9871524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"¹⁸ F-FDG Brain PET/MRI in Amyotrophic Lateral Sclerosis- Frontotemporal Spectrum Disorder (ALS-FTSD).","authors":"Faizullah Mashriqi,&nbsp;Bibhuti B Mishra,&nbsp;Luca Giliberto,&nbsp;Ana M Franceschi","doi":"10.1055/s-0043-1760762","DOIUrl":"https://doi.org/10.1055/s-0043-1760762","url":null,"abstract":"<p><p>Amyotrophic lateral sclerosis (ALS) is a fatal and progressive neurodegenerative disorder involving both upper and lower motor neurons. Interestingly, 15 to 41% of patients with ALS have concomitant frontotemporal dementia (FTD). Approximately, 50% of patients with ALS can copresent with a broader set of neuropsychological pathologies that do not meet FTD diagnostic criteria. This association resulted in revised and expanded criteria establishing the ALS-frontotemporal spectrum disorder (FTSD). In this case report, we review background information, epidemiology, pathophysiology, and structural and molecular imaging features of ALS-FTSD.</p>","PeriodicalId":23742,"journal":{"name":"World Journal of Nuclear Medicine","volume":"22 2","pages":"135-139"},"PeriodicalIF":0.6,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10202568/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9871531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}