18 F-FDG脑PET/MRI在肌萎缩侧索硬化症-额颞叶谱障碍(ALS-FTSD)中的表现。

IF 0.6 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

World Journal of Nuclear Medicine Pub Date : 2023-06-01 DOI:10.1055/s-0043-1760762

Faizullah Mashriqi, Bibhuti B Mishra, Luca Giliberto, Ana M Franceschi

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引用次数: 0

摘要

肌萎缩性侧索硬化症(ALS)是一种累及上、下运动神经元的致死性进行性神经退行性疾病。有趣的是，15%至41%的ALS患者伴有额颞叶痴呆(FTD)。大约50%的ALS患者可以表现出不符合FTD诊断标准的更广泛的神经心理病理。这种联系导致了als -额颞叶谱系障碍(FTSD)标准的修订和扩展。在本病例报告中，我们综述了ALS-FTSD的背景资料、流行病学、病理生理学以及结构和分子影像学特征。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

18 F-FDG Brain PET/MRI in Amyotrophic Lateral Sclerosis- Frontotemporal Spectrum Disorder (ALS-FTSD).

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¹⁸ F-FDG Brain PET/MRI in Amyotrophic Lateral Sclerosis- Frontotemporal Spectrum Disorder (ALS-FTSD).

Amyotrophic lateral sclerosis (ALS) is a fatal and progressive neurodegenerative disorder involving both upper and lower motor neurons. Interestingly, 15 to 41% of patients with ALS have concomitant frontotemporal dementia (FTD). Approximately, 50% of patients with ALS can copresent with a broader set of neuropsychological pathologies that do not meet FTD diagnostic criteria. This association resulted in revised and expanded criteria establishing the ALS-frontotemporal spectrum disorder (FTSD). In this case report, we review background information, epidemiology, pathophysiology, and structural and molecular imaging features of ALS-FTSD.

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来源期刊

World Journal of Nuclear Medicine RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-

自引率

16.70%

发文量

118

审稿时长

48 weeks