Wound management & prevention最新文献_第3页

Repair of facial dog bite wound utilizing cryopreserved umbilical cord allograft. 利用低温保存的脐带异体移植修复面部被狗咬伤的伤口。

IF 1 4区医学

Wound management & prevention Pub Date : 2024-06-01 DOI: 10.25270/wmp.23017

Addison Ye, Kyle P Davis, Zachary Anderson, Larry Hartzell

{"title":"Repair of facial dog bite wound utilizing cryopreserved umbilical cord allograft.","authors":"Addison Ye, Kyle P Davis, Zachary Anderson, Larry Hartzell","doi":"10.25270/wmp.23017","DOIUrl":"10.25270/wmp.23017","url":null,"abstract":"Background: In the United States, craniofacial injuries are the most frequently observed traumas in the pediatric population. Human birth tissue products contain growth factors, cytokines, and signaling molecules that can be potentially harnessed for tissue regeneration and wound healing.Purpose: A cryopreserved ultra-thick amniotic membrane (AM) allograft wound dressing was used in a patient with significant facial soft tissue loss due to a dog bite injury.Methods: This is a single case report of a pediatric patient. After obtaining IRB exemption, operative and postoperative clinic notes were reviewed.Results: A 10-year-old female presented to the emergency department after suffering a dog bite to her left cheek and upper lip, resulting in tissue loss. A cryopreserved ultra-thick AM allograft was used to cover the area of tissue loss as part of surgical reconstruction. The patient was followed up at 1 week, 3 weeks, 4 months, and 1 year after the graft was placed, and rapid healing and full epithelialization were achieved in addition to scar contracture due to wound location.Conclusion: In the setting of acute trauma and tissue loss, human birth tissue was found to promote epithelialization and regenerative healing of facial tissues.","PeriodicalId":23741,"journal":{"name":"Wound management & prevention","volume":"70 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141499150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effect of web-based training given to nurses on the prevention of pressure injury in patients hospitalized in the anesthesiology and reanimation intensive care unit: quasi-experimental pre-test post-test research. 为护士提供的网络培训对预防麻醉科和复苏重症监护室住院病人压力损伤的影响：准实验性前测后测研究。

IF 1 4区医学

Wound management & prevention Pub Date : 2024-06-01 DOI: 10.25270/wmp.23013

Hatice Erdoğan, Nevin Kanan

{"title":"The effect of web-based training given to nurses on the prevention of pressure injury in patients hospitalized in the anesthesiology and reanimation intensive care unit: quasi-experimental pre-test post-test research.","authors":"Hatice Erdoğan, Nevin Kanan","doi":"10.25270/wmp.23013","DOIUrl":"10.25270/wmp.23013","url":null,"abstract":"Background: The knowledge, attitudes, and behaviors of intensive care nurses concerning the prevention of pressure injury (PI) may be positively affected by education.Purpose: To evaluate the effect of web-based training given to nurses on their knowledge of, attitudes about, and behaviors in the prevention of PI.Methods: This study was conducted between May 2019 and December 2019 with a pre-test and post-test design. The study sample consisted of 22 nurses and 80 patients. A link to the educational video prepared for the prevention of PIs was sent to the nurses' mobile phones.Results: The training had a significant positive effect on nurses' level of knowledge of and attitudes toward PI prevention (P < .001 and P = .042, respectively). In group 1, comprising 40 patients who received treatment before nurses' training, 2.5% of patients had stage 1 PI on day 1 and 7.5% had stage 1 PI on day 7, and 2.5% had stage 4 PI on day 7. In group 2, comprising 40 patients who received treatment after nurses' training, 2.5% of patients had stage 1 PI on day 1 and 2.5% had stage 1 PI on day 7.Conclusion: Nurses' knowledge of and attitudes and behaviors toward PI prevention were improved following the web-based training, and the stage and rate of PI were lower in patients who received care after nurses received the training.","PeriodicalId":23741,"journal":{"name":"Wound management & prevention","volume":"70 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141499151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of nursing students' knowledge levels and attitudes in incontinence-associated dermatitis management through game-based learning: a mixed methods study. 通过游戏式学习调查护理专业学生在失禁相关皮炎管理方面的知识水平和态度：一项混合方法研究。

IF 1 4区医学

Wound management & prevention Pub Date : 2024-06-01 DOI: 10.25270/wmp.23077

Tuba Sengul, Nurten Kaya, Holly Kirkland-Kyhn, Dilek Yilmaz Akyaz, Tuğba Cevizci, Tuğçe Oldaç, Hamza Can Koyun

{"title":"Investigation of nursing students' knowledge levels and attitudes in incontinence-associated dermatitis management through game-based learning: a mixed methods study.","authors":"Tuba Sengul, Nurten Kaya, Holly Kirkland-Kyhn, Dilek Yilmaz Akyaz, Tuğba Cevizci, Tuğçe Oldaç, Hamza Can Koyun","doi":"10.25270/wmp.23077","DOIUrl":"10.25270/wmp.23077","url":null,"abstract":"Purpose: This study aimed to assess nursing students' knowledge levels and attitudes towards the etiology, risk factors, and preventive measures of incontinence-associated dermatitis (IAD) using an escape room game.Design: A mixed-method study.Subjects and setting: The sample size of the study was 32 students.Methods: Quantitative data obtained with the Knowledge, Attitude and Practice of Nurses in Managing Incontinence-Associated Dermatitis Questionnaire (KAP-IAD-Q) and qualitative data obtained through FGDs following the Consolidated Criteria for Reporting Qualitative Research (COREQ) checklist were analyzed using a thematic approach.Results: The average age of the participants was 22.63 ± 0.90, 87.5% of them were female (n=28), and 50% were third (n=16) and fourth-year students (n=16). KAP-IAD-Q total posttest score (88.06+7.00) was found to be high. Data obtained from the FGDs were categorized under 3 main themes: main focus areas during participation in the IAD-themed escape room game; advantages and disadvantages of teamwork in IAD management; and the game's contribution to a better understanding and classification of IAD.Conclusions: The use of the escape room game facilitated high, fast, and efficient learning of IAD knowledge and attitudes. It revealed challenges in collaborative decision-making, accurate diagnosis, distinguishing from other wounds, and attitude development in the management of IAD.","PeriodicalId":23741,"journal":{"name":"Wound management & prevention","volume":"70 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141499149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Incidence and risk factors of operating room-acquired pressure injury: a cross-sectional study. 手术室获得性压伤的发生率和风险因素：一项横断面研究。

IF 1 4区医学

Wound management & prevention Pub Date : 2024-06-01 DOI: 10.25270/wmp.23037

Ayşegül Savcı, Kevser Karacabay, Esma Aydın

{"title":"Incidence and risk factors of operating room-acquired pressure injury: a cross-sectional study.","authors":"Ayşegül Savcı, Kevser Karacabay, Esma Aydın","doi":"10.25270/wmp.23037","DOIUrl":"10.25270/wmp.23037","url":null,"abstract":"Background: Operating room-acquired pressure injury (PI) is defined as PI that develops within the first 48 to 72 hours after surgery.Purpose: To determine the incidence and risk factors of operating room-acquired PI.Methods: This descriptive cross-sectional study was conducted at a university hospital in Turkey between May 20, 2021, and December 20, 2021, and included 309 patients who met the inclusion criteria. The study was reported based on the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) checklist for cross-sectional studies.Results: Operating room-acquired PI developed in 5.8% of the patients in this study. Moreover, 54.4% of the patients had medical devices, and medical device-acquired PI occurred in 4.2% of these patients (7/168). Patient age, hemodynamic parameters, and albumin level, as well as duration of surgery, were found to affect the development of operating room-acquired PI.Conclusion: Surgical nurses are responsible for both recognizing situations that may result in perioperative PI and taking necessary precautions. It is recommended that nurses identify existing and potential preoperative, intraoperative, and postoperative risks that impair skin integrity and affect tissue oxygenation to reduce the risk of operating room-acquired PI.","PeriodicalId":23741,"journal":{"name":"Wound management & prevention","volume":"70 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141499148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Concentrated surfactant gel dressing for effective wound healing in pediatric patients: a case series. 浓缩表面活性剂凝胶敷料促进儿科患者伤口有效愈合：病例系列。

IF 1 4区医学

Wound management & prevention Pub Date : 2024-06-01 DOI: 10.25270/wmp.22081

Vita Boyar

{"title":"Concentrated surfactant gel dressing for effective wound healing in pediatric patients: a case series.","authors":"Vita Boyar","doi":"10.25270/wmp.22081","DOIUrl":"10.25270/wmp.22081","url":null,"abstract":"Background: CSG dressing is water-soluble and helps to hydrate the wound, control exudate, and provide gentle debridement by virtue of a high concentration of surfactant micelles. The primary objective of this retrospective case series is to report on the feasibility of CSG use in pediatric wounds and its mechanism of action. The secondary aim was to measure pain during application and removal of CSG.Methods: Eight pediatric patients ranging in age from newborn to a few months old with wounds requiring medical intervention were treated with CSG. The CSG dressing was applied twice daily at initiation of treatment in some patients, but mostly once daily. NIPS was utilized for pain measurements.Results: Near-complete healing of wounds was observed by the end of treatment duration, which was only a few days. The calm temperament of these patients during dressing changes and objective NIPS suggested minimal to no pain. None of the patients experienced any adverse events related to the use of this dressing.Conclusion: The CSG dressing could be the dressing of choice in this population to enhance debridement and maintain moist healing and support granulation, either proactively or if other treatments fail.","PeriodicalId":23741,"journal":{"name":"Wound management & prevention","volume":"70 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141499144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of topical insulin on second-degree burn wound healing: brief report. 局部胰岛素对二度烧伤伤口愈合的影响：简要报告。

IF 1 4区医学

Wound management & prevention Pub Date : 2024-06-01 DOI: 10.25270/wmp.23023

Vagner Franco da Silveira, Juliany Lino Gomes Silva, Maria Helena Melo Lima, Mario Jose Abdalla Saad

{"title":"Effects of topical insulin on second-degree burn wound healing: brief report.","authors":"Vagner Franco da Silveira, Juliany Lino Gomes Silva, Maria Helena Melo Lima, Mario Jose Abdalla Saad","doi":"10.25270/wmp.23023","DOIUrl":"10.25270/wmp.23023","url":null,"abstract":"Background: Burns are classified according to their mechanism of injury, depth, affected body area, affected region or part of the body, and extent of the lesions. Topical insulin modulates the healing process. However, studies evaluating the effects of topical insulin treatment on burns in human patients are lacking.Purpose: The purpose of this study was to investigate the effects of topical insulin on healing time of second-degree burns.Methods: In this nonrandomized clinical trial, patients with second-degree burns were allocated to a control group (CG) or an intervention group (IG) in which wounds were treated with 1% silver sulfadiazine and topical insulin, respectively.Results: Healing time was significantly shorter in the IG relative to the CG (9.1 ± 1.9 days and 12.7 ± 3.3 days, respectively; P < .05). The estimated burn area was similar in both groups (CG 1.44 ± 1.0%; IG 1.42 ± 0.53%).Conclusion: In this study, topical insulin reduced healing time in second-degree burns. Further investigation is warranted to support wider use in clinical practice.","PeriodicalId":23741,"journal":{"name":"Wound management & prevention","volume":"70 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141499145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Extracorporeal shockwave therapy (ESWT) in an outpatient wound care clinic: case series analysis of a non-invasive technology in the management of chronic wounds for wound bed preparation. 体外冲击波疗法（ESWT）在门诊伤口护理诊所的应用：对用于伤口床准备的非侵入性慢性伤口管理技术的病例系列分析。

IF 1 4区医学

Wound management & prevention Pub Date : 2024-06-01 DOI: 10.25270/wmp.22090

Denise Nemeth, Jayesh Shah

{"title":"Extracorporeal shockwave therapy (ESWT) in an outpatient wound care clinic: case series analysis of a non-invasive technology in the management of chronic wounds for wound bed preparation.","authors":"Denise Nemeth, Jayesh Shah","doi":"10.25270/wmp.22090","DOIUrl":"10.25270/wmp.22090","url":null,"abstract":"Background: Extracorporeal shockwave therapy (ESWT) has been shown to reduce wound dimensions and healing time in chronic wounds and should be considered a valuable tool in the healing of chronic complex lower extremity wounds.Purpose: The aim of this small case series was to evaluate the effect of ESWT on complex chronic wounds in patients with multiple comorbidities in a medically underserved outpatient wound care clinic setting.Methods: All patients had baseline wound measurements taken. Pictures of the wounds were also taken at the time of the initial visit. Patients selected for ESWT received weekly treatments for a maximum recorded duration of 12 weeks in the form of focused electro-hydraulic acoustic pulses. Wound beds were cleansed according to standard of care.Results: Thirteen patients were followed with a total of 18 wounds treated. After retrospectively analyzing the data, 3 subjects and a total of 5 wounds were excluded, leaving 10 total subjects and 13 wounds. Out of these wounds, 12 healed completely by or before week 12 of ESWT. All wounds demonstrated significant wound dimension reduction during the first 12 weeks of treatment.Conclusion: ESWT could offer accessible, fast, safe, and cost-effective management of some complex chronic wounds. Further research is needed to validate these findings.","PeriodicalId":23741,"journal":{"name":"Wound management & prevention","volume":"70 2","pages":""},"PeriodicalIF":1.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141499146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of a theory-based foot care education program on self-efficacy and adaptation in patients with diabetes in Turkey: a randomized controlled trial. 基于理论的足部护理教育计划对土耳其糖尿病患者自我效能和适应能力的影响：随机对照试验。

IF 1 4区医学

Wound management & prevention Pub Date : 2024-03-01 DOI: 10.25270/wmp.23007

Arzu Güngör Tolasa, Asiye Durmaz Akyol

{"title":"Effectiveness of a theory-based foot care education program on self-efficacy and adaptation in patients with diabetes in Turkey: a randomized controlled trial.","authors":"Arzu Güngör Tolasa, Asiye Durmaz Akyol","doi":"10.25270/wmp.23007","DOIUrl":"10.25270/wmp.23007","url":null,"abstract":"Background: Persons with diabetes often face significant foot problems due to inadequate foot care, and foot care training programs could be beneficial for these patients.Purpose: To examine the effects of diabetic foot care training on self-efficacy and adaptation based on Social Cognitive Theory and the Roy Adaptation Model.Methods: In this randomized controlled study, 80 patients treated in the endocrine polyclinic of an education and research hospital in İzmir, Turkey, were randomized to intervention (n = 40) or control (n = 40). The intervention group received diabetic foot care training at 1 month, 3 months, and 6 months. Using a diabetic foot model, foot care training was given on diabetic foot care practices; in addition, a foot care training booklet prepared by the researchers was provided. Foot care behaviors, self-efficacy, and adaptation were reevaluated after the training and education. Data were collected at baseline, 1 month, 3 months, and 6 months in both groups.Results: Diabetic foot care training and telephone follow-up were effective in improving foot care behaviors and facilitating the coping and adaptation process of individuals with diabetes, as well as in increasing their self-efficacy regarding foot care.Conclusions: When providing theory-based diabetic foot education, the use of visual materials along with verbal instruction as well as telephone follow-ups to evaluate training effectiveness increases patients' self-efficacy and adaptation.","PeriodicalId":23741,"journal":{"name":"Wound management & prevention","volume":"70 1","pages":""},"PeriodicalIF":1.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140872290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of recombinant human epidermal growth factor in pressure injury healing: evidence from Chinese randomized controlled trials. 重组人表皮生长因子对压力损伤愈合的疗效：来自中国随机对照试验的证据。

IF 1 4区医学

Wound management & prevention Pub Date : 2024-03-01 DOI: 10.25270/wmp.22092

Meng-Wei Ge, Fei-Hong Hu, Yi-Jie Jia, Wen Tang, Wan-Qing Zhang, Hong-Lin Chen

{"title":"Efficacy of recombinant human epidermal growth factor in pressure injury healing: evidence from Chinese randomized controlled trials.","authors":"Meng-Wei Ge, Fei-Hong Hu, Yi-Jie Jia, Wen Tang, Wan-Qing Zhang, Hong-Lin Chen","doi":"10.25270/wmp.22092","DOIUrl":"10.25270/wmp.22092","url":null,"abstract":"Objective: To evaluate the efficacy of recombinant human epidermal growth factor (rhEGF) in healing pressure injuries (PIs).Methods: A meta-analysis was conducted of randomized controlled trials (RCTs) involving rhEGF in the treatment of PIs that were identified in PubMed, Web of Science, the Cochrane Library, and China National Knowledge Infrastructure (CNKI). The population, intervention, comparison, outcomes, study design (PICOS) strategy was applied to determine analysis eligibility. The Cochrane risk of bias tool was used, and statistical analysis, including sensitivity analysis, was performed of 3 outcomes indicators: the primary outcome was total efficacy of rhEGF in treating PIs, and the secondary outcomes were the proportion of complete healing and the time to complete healing. Total efficacy refers to the proportion of cases that have been cured, obviously effective, or effective. Complete healing refers to cases where the wound has healed, scabbed, and the scab has sloughed off.Results: Sixteen RCTs were included, comprising a total of 1,206 patients. Study and control group size varied by outcomes. The total effective healing rate in rhEGF group was 97.18%, which was significantly higher than 83.38% in control group (OR: 5.69, [95% CI: 3.61, 8.97], z=7.49, P < .001). The proportion of complete healing in the rhEGF group was 73.30%, which was higher than 39.52% in control group (OR: 3.88, [95% CI: 3.01, 5.01], z=10.39, P < .001). Furthermore, the healing time using rhEGF was shorter (SMD: -2.14 days, [95% CI: -2.60, -1.67], z=9.07, P < .001). Sensitivity analyses indicated that the results were robust.Conclusions: The meta-analysis indicated that rhEGF was effective in healing PIs with few negative effects. Further research beyond Chinese populations involving larger studies and studies that distinguish between results found in using rhEGF alone or in combination are recommended.","PeriodicalId":23741,"journal":{"name":"Wound management & prevention","volume":"70 1","pages":""},"PeriodicalIF":1.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140857958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The protective effect of a new absorbent incontinence design against an alkaline pH challenge on the epidermal barrier. 新型尿失禁吸收设计在碱性 pH 值挑战下对表皮屏障的保护作用。

IF 1 4区医学

Wound management & prevention Pub Date : 2024-03-01 DOI: 10.25270/wmp.23057

Olga Vechter, Yana Arlouskaya, Niuosha Sanaeifar, Rüdiger Kesselmeier, Pia Beer, Janina Tiemann, Agnieszka Segiet, Daniel Rabczenko, Robert Garcia, Luca Ferrandi, Hans Smola

{"title":"The protective effect of a new absorbent incontinence design against an alkaline pH challenge on the epidermal barrier.","authors":"Olga Vechter, Yana Arlouskaya, Niuosha Sanaeifar, Rüdiger Kesselmeier, Pia Beer, Janina Tiemann, Agnieszka Segiet, Daniel Rabczenko, Robert Garcia, Luca Ferrandi, Hans Smola","doi":"10.25270/wmp.23057","DOIUrl":"10.25270/wmp.23057","url":null,"abstract":"Background: Incontinence-associated dermatitis (IAD) is one of the most common complications of incontinence. Improved diaper designs can minimize the occurrence of IAD.Purpose: To develop a novel diaper design to minimize the damaging effects of incontinence on the epidermal barrier.Methods: An optimized diaper design was tested for surface dryness (ie, rewet), maintenance of a skin-adapted surface pH of 5.5, and ability to protect epidermal barrier function from an alkaline pH 10.7 challenge.Results: The diapers released a mean (standard deviation [SD]) of 1.2 (0.2) mg/cm2 of solution under pressure after the first loading and a mean of 2.9 (1.7) mg/cm2 after the second loading. The surface pH remained between 4.5 and 5.5 over 5 hours. In healthy skin, transepidermal water loss (TEWL) increased by a mean of 3.43 (4.67) g/m2/h after the alkaline urine solution challenge with the new diaper design versus a mean of 8.38 (5.67) g/m2/h with a cellulose patch (P < .001) as a control. The mean erythema readings were 1.18 (1.30) g/m2/h for the new design and 2.56 (1.25) g/m2/h for the cellulose patches (P < .001).Conclusion: The new diaper design minimizes rewetting, maintains an acidic surface, and protects the epidermal barrier against an alkaline pH challenge. This design may help prevent IAD.","PeriodicalId":23741,"journal":{"name":"Wound management & prevention","volume":"70 1","pages":""},"PeriodicalIF":1.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140851768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0