VirusDisease最新文献_第8页

Pathological findings in respiratory organs and blood circulation in patients with isolated DRTB and DRTB/HIV/AIDS co-infection (according to autopsy data) 单独感染 DRTB 和 DRTB/HIV/AIDS 合并感染患者呼吸器官和血液循环的病理结果（根据尸检数据）。

VirusDisease Pub Date : 2024-02-01 DOI: 10.1007/s13337-023-00855-6

Svitlana Poliakova, Shrouq Sabaileh, Tamara Narbutova, Marianna Lytvynenko, Olesia Balazh

引用次数: 0

From pigs to wild boars, the rise of African swine fever in India 从猪到野猪，非洲猪瘟在印度的兴起

VirusDisease Pub Date : 2023-12-20 DOI: 10.1007/s13337-023-00853-8

Mousumi Bora

引用次数: 0

Complete genome sequence and phylogenetic analysis of feline panleukopenia virus from India 印度猫泛白细胞减少症病毒的完整基因组序列和系统发育分析

VirusDisease Pub Date : 2023-12-19 DOI: 10.1007/s13337-023-00854-7

P. Raja, K. S. Mallika, V. Y. Viva, M. Parthiban, G. Sathish, V. Vinitha, S. Parthiban, G. D. Raj

引用次数: 0

Immunodominant conserved moieties on spike protein of SARS-CoV-2 renders virulence factor for the design of epitope-based peptide vaccines. SARS-CoV-2刺突蛋白的免疫优势保守片段为表位肽疫苗的设计提供了毒力因子。

VirusDisease Pub Date : 2023-12-01 Epub Date: 2023-11-23 DOI: 10.1007/s13337-023-00852-9

Subhashree Mohapatra, Santosh Kumar, Shashank Kumar, Atul Kumar Singh, Bismita Nayak

{"title":"Immunodominant conserved moieties on spike protein of SARS-CoV-2 renders virulence factor for the design of epitope-based peptide vaccines.","authors":"Subhashree Mohapatra, Santosh Kumar, Shashank Kumar, Atul Kumar Singh, Bismita Nayak","doi":"10.1007/s13337-023-00852-9","DOIUrl":"10.1007/s13337-023-00852-9","url":null,"abstract":"The outbreak of novel SARS-CoV-2 virion has wreaked havoc with a high prevalence of respiratory illness and high transmission due to a vague understanding of the viral antigenicity, augmenting the dire challenge to public health globally. This viral member necessitates the expansion of diagnostic and therapeutic tools to track its transmission and confront it through vaccine development. Therefore, prophylactic strategies are mandatory. Virulent spike proteins can be the most desirable candidate for the computational design of vaccines targeting SARS-CoV-2, followed by the meteoric development of immune epitopes. Spike protein was characterized using existing bioinformatics tools with a unique roadmap related to the immunological profile of SARS-CoV-2 to predict immunogenic virulence epitopes based on antigenicity, allergenicity, toxicity, immunogenicity, and population coverage. Applying in silico approaches, a set of twenty-four B lymphocyte-based epitopes and forty-six T lymphocyte-based epitopes were selected. The predicted epitopes were evaluated for their intrinsic properties. The physico-chemical characterization of epitopes qualifies them for further in vitro and in vivo analysis and pre-requisite vaccine development. This study presents a set of screened epitopes that bind to HLA-specific allelic proteins and can be employed for designing a peptide vaccine construct against SARS-CoV-2 that will confer vaccine-induced protective immunity due to its structural stability.Supplementary information: The online version contains supplementary material available at 10.1007/s13337-023-00852-9.","PeriodicalId":23708,"journal":{"name":"VirusDisease","volume":"34 4","pages":"456-482"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686954/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138478719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Begomovirus and DNA-satellites association with mosaic and leaf curl disease of Solanum nigrum and Physalis minima: the new hosts for chilli leaf curl virus. 与龙葵花叶病和卷叶病相关的begomavirus和dna -卫星:辣椒卷叶病毒的新宿主。

VirusDisease Pub Date : 2023-12-01 Epub Date: 2023-11-20 DOI: 10.1007/s13337-023-00850-x

V Venkataravanappa, K V Ashwathappa, Shridhar Hiremath, L Manjunatha, K S Shankarappa, M Krishna Reddy, C N Lakshminarayana Reddy

{"title":"Begomovirus and DNA-satellites association with mosaic and leaf curl disease of Solanum nigrum and Physalis minima: the new hosts for chilli leaf curl virus.","authors":"V Venkataravanappa, K V Ashwathappa, Shridhar Hiremath, L Manjunatha, K S Shankarappa, M Krishna Reddy, C N Lakshminarayana Reddy","doi":"10.1007/s13337-023-00850-x","DOIUrl":"10.1007/s13337-023-00850-x","url":null,"abstract":"The numerous plants of Solanum nigrum L, and Physalis minima L, well-known weeds with medicinal properties in agriculture and horticulture crops exhibiting severe mosaic, enation and leaf curl symptoms, were collected from the Varanasi and Mirzapur districts of Uttar Pradesh, India. The begomovirus infection in S. nigrum and P. minima was validated by PCR using virus-specific primers. The whole genome of the represented isolate of S. nigrum (SN1), P. minima (PM1), and beta satellite was amplified, cloned and sequenced. The SDT analysis showed that the DNA-A of PM1 and SN1 isolate showed the highest nt identity of 87.4 to 99.1%, with several chilli leaf curl virus (ChiLCuV) isolates from India and Oman, respectively. The betasatellite sequence (PM1β) obtained from the PM1 isolate showed a very low identity of 83.1-84.5%. A demarcation threshold of 91% for betasatellite species delineation has led to identifying a new betasatellite in the PM1 sample. This unique betasatellite has been named \"physalis minima leaf curl betasatellite,\" indicating its novelty with the plant. Whereas, betasatellite sequence (SN1β) obtained from the SN1 sample showed 86.8-91.2% nucleotide identity with ChiLCB isolates infecting several crops in Indian subcontinents. The RDP analysis of the viral genome and betasatellite of SN1 and PM1 isolates revealed recombination in substantial portions of their genetic makeup, which appeared to have originated from pre-existing begomoviruses known to infect diverse host species. The present research also highlights the potential role of these plants as significant reservoir hosts for ChiLCuV in chili plants.Supplementary information: The online version contains supplementary material available at 10.1007/s13337-023-00850-x.","PeriodicalId":23708,"journal":{"name":"VirusDisease","volume":"34 4","pages":"504-513"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686937/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138478718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular detection of bovine alphaherpesvirus-1 in cases of reproductive disorders among cattle and buffaloes in Gujarat. 古吉拉特邦牛和水牛生殖障碍病例中牛甲疱疹病毒-1的分子检测。

VirusDisease Pub Date : 2023-12-01 Epub Date: 2023-11-15 DOI: 10.1007/s13337-023-00851-w

G Tejaswi, R V Chandrasekhar Reddy, N M Ponnanna, L N Sarangi

{"title":"Molecular detection of bovine alphaherpesvirus-1 in cases of reproductive disorders among cattle and buffaloes in Gujarat.","authors":"G Tejaswi, R V Chandrasekhar Reddy, N M Ponnanna, L N Sarangi","doi":"10.1007/s13337-023-00851-w","DOIUrl":"10.1007/s13337-023-00851-w","url":null,"abstract":"Bovine alphaherpesvirus-1 (BoAHV-1) is an important viral pathogen that causes significant economic losses to the dairy industry. The present study aimed to determine the prevalence of BoAHV-1 in cases of bovine reproductive disorder. Clinical samples were collected from various villages in Gujarat using specialized FTA® cards and were tested using real-time PCR assay targeting the gB gene of BoAHV-1. Out of 401 animals, 18.20% (95% CI: 14.74-22.28%) tested positive for BoAHV-1 DNA. The percentage positivity of BoAHV-1 was 20.37% in abortion cases and 19.55% in retention of fetal membrane cases, while only one out of nine metritis cases screened in the study was positive for BoAHV-1 DNA. A higher percentage positivity in buffaloes (22.14%) compared to cattle (16.30%) was recorded, but this difference was not statistically significant (p = 0.169). The frequency of BoAHV-1 detection was higher among crossbreeds (16.76%) and exotics (19.61%) than among indigenous cattle (8.82%), although this difference was not statistically significant (p = 0.400). There was also no significant difference in frequency distribution among animals of varying parity, ranging from 15.20 to 33.33% (p = 0.540). This study confirms the widespread circulation of BoAHV-1 and highlights the need for its control and prevention.","PeriodicalId":23708,"journal":{"name":"VirusDisease","volume":"34 4","pages":"526-530"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10686898/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138478720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Co-circulation and genetic characteristics of porcine circoviruses in postweaning multisystemic wasting syndrome cases in commercial swine farms 猪圆环病毒在商业猪场断奶后多系统消耗综合征病例中的共循环和遗传特征

VirusDisease Pub Date : 2023-11-11 DOI: 10.1007/s13337-023-00849-4

Danh Cong Lai, Duyen My Thi Nguyen, Toan Tat Nguyen, Tram Ngoc Thi Ngo, Duy Tien Do

引用次数: 0

Application of machine learning models for risk estimation and risk prediction of classical swine fever in Assam, India 机器学习模型在印度阿萨姆邦典型猪瘟风险估计和风险预测中的应用

VirusDisease Pub Date : 2023-11-10 DOI: 10.1007/s13337-023-00847-6

Kuralayanapalya Puttahonnappa Suresh, Nagendra Nath Barman, Tarushree Bari, Dikshitha Jagadish, Bylaiah Sushma, H. V. Darshan, Sharanagouda S. Patil, Mousumi Bora, Abhijit Deka

引用次数: 0

Molecular characterization of G and F protein genes of bovine respiratory syncytial virus detected from dead calves caused by severe respiratory syndrome: emergence of novel mutations and their importance 从严重呼吸综合征死犊中检测到的牛呼吸道合胞病毒G和F蛋白基因的分子特征:新突变的出现及其重要性

VirusDisease Pub Date : 2023-11-07 DOI: 10.1007/s13337-023-00846-7

Murat Kaplan, Emre Özan, Kemal Pekmez, Abdurrahman Anıl Çağırgan, Fatih Arslan

引用次数: 0

Evidence for the natural infection of cucurbit chlorotic yellows virus (CCYV) in lettuce plants from India 印度莴苣自然感染葫芦绿黄病毒(CCYV)的证据

VirusDisease Pub Date : 2023-11-07 DOI: 10.1007/s13337-023-00848-5

Ashwini Kumar, Shakshi Choudhary, Yvonne A. Lyngdoh, Virendra K. Baranwal, Rakesh K. Jain, Y. B. Basavaraj

引用次数: 0