{"title":"The occurrence of propofol injection pain in the emergency department: an exploratory analysis.","authors":"Mischa Veen, M Christien van der Linden","doi":"10.5847/wjem.j.1920-8642.2025.023","DOIUrl":"10.5847/wjem.j.1920-8642.2025.023","url":null,"abstract":"","PeriodicalId":23685,"journal":{"name":"World journal of emergency medicine","volume":"16 2","pages":"161-163"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11930562/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143711445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yiyao Bao, Jing Ye, Lijun Guan, Caina Gao, Lei Hu, Linhua Tan
{"title":"Pediatric bronchial rupture: outcomes in four cases.","authors":"Yiyao Bao, Jing Ye, Lijun Guan, Caina Gao, Lei Hu, Linhua Tan","doi":"10.5847/wjem.j.1920-8642.2024.089","DOIUrl":"10.5847/wjem.j.1920-8642.2024.089","url":null,"abstract":"","PeriodicalId":23685,"journal":{"name":"World journal of emergency medicine","volume":"16 1","pages":"85-87"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11788115/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wachira Wongtanasarasin, Daniel K Nishijima, Wanrudee Isaranuwatchai, Jeffrey S Hoch
{"title":"Real-world cost-effectiveness of targeted temperature management in out-of-hospital cardiac arrest survivors: results from an academic medical center.","authors":"Wachira Wongtanasarasin, Daniel K Nishijima, Wanrudee Isaranuwatchai, Jeffrey S Hoch","doi":"10.5847/wjem.j.1920-8642.2025.012","DOIUrl":"10.5847/wjem.j.1920-8642.2025.012","url":null,"abstract":"<p><strong>Background: </strong>Targeted temperature management (TTM) is a common therapeutic intervention, yet its cost-effectiveness remains uncertain. This study aimed to evaluate the real-world cost-effectiveness of TTM compared with that of conventional care in adult out-of-hospital cardiac arrest (OHCA) survivors using clinical patient-level data.</p><p><strong>Methods: </strong>We conducted a retrospective cohort study at an academic medical center in the USA to assess the cost-effectiveness of TTM in adult non-traumatic OHCA survivors between 1 January, 2019 and 30 June, 2023. The primary outcome was survival to hospital discharge. Incremental cost-effectiveness ratios (ICERs) were calculated and compared with various decision makers' willingness to pay. Cost-effectiveness acceptability curves were utilized to evaluate the economic attractiveness of TTM. Uncertainty about the incremental cost and effect was explored with a 95% confidence ellipse.</p><p><strong>Results: </strong>Among 925 non-traumatic OHCA survivors, only 30 (3%) received TTM. After adjusting for potential confounders, the TTM group did not demonstrate a significantly lower cost (delta cost -$5,141, 95% confidence interval [95% CI]: $-35,347 to $25,065, P=0.79) and higher survival to hospital discharge (delta effect 6%, 95% CI: -11% to 23%, P=0.41). Additionally, a 95% confidence ellipse indicated uncertainty reflected by evidence that the true value of the ICER could be in any of the quadrants of the cost-effectiveness plane.</p><p><strong>Conclusion: </strong>Although TTM did not demonstrate a clear survival benefit in this study, its potential cost-effectiveness warrants further investigation with larger sample sizes. These findings highlight the need for additional research to optimize TTM use in OHCA care and inform resource allocation decisions.</p>","PeriodicalId":23685,"journal":{"name":"World journal of emergency medicine","volume":"16 1","pages":"28-34"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11788109/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Transesophageal lung ultrasonography in empyema detection: a case report.","authors":"Issac Cheong, Francisco Marcelo Tamagnone","doi":"10.5847/wjem.j.1920-8642.2025.029","DOIUrl":"10.5847/wjem.j.1920-8642.2025.029","url":null,"abstract":"","PeriodicalId":23685,"journal":{"name":"World journal of emergency medicine","volume":"16 2","pages":"189-191"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11930560/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143711448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Eosinophilia and clonorchiasis presenting as fever of unknown origin in adult patients.","authors":"Jie Zhong, Xin Zhou, Wei Gu","doi":"10.5847/wjem.j.1920-8642.2024.069","DOIUrl":"10.5847/wjem.j.1920-8642.2024.069","url":null,"abstract":"","PeriodicalId":23685,"journal":{"name":"World journal of emergency medicine","volume":"16 1","pages":"91-93"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11788103/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Keven Vachon, Geneviève Gravel, Samuel Leduc, Alexandra Larouche, Myriam Mallet, David Simonyan, Mahukpe Narcisse Ulrich Singbo, Julie Ouellet-Pelletier, Simon Berthelot
{"title":"Fever without source in infants aged 22-60 days: how laboratory tests perform at identifying bacterial infections and predicting the need for a lumbar puncture?","authors":"Keven Vachon, Geneviève Gravel, Samuel Leduc, Alexandra Larouche, Myriam Mallet, David Simonyan, Mahukpe Narcisse Ulrich Singbo, Julie Ouellet-Pelletier, Simon Berthelot","doi":"10.5847/wjem.j.1920-8642.2025.004","DOIUrl":"10.5847/wjem.j.1920-8642.2025.004","url":null,"abstract":"","PeriodicalId":23685,"journal":{"name":"World journal of emergency medicine","volume":"16 1","pages":"74-77"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11788111/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Samir Hammoud, Kevin Tishkowski, Ahmed Hammad, Jehan Barbat, Alysse Cohen, Barry Brenner
{"title":"Identifying glass foreign bodies using conventional X-ray in a gelatinous model.","authors":"Samir Hammoud, Kevin Tishkowski, Ahmed Hammad, Jehan Barbat, Alysse Cohen, Barry Brenner","doi":"10.5847/wjem.j.1920-8642.2025.002","DOIUrl":"10.5847/wjem.j.1920-8642.2025.002","url":null,"abstract":"","PeriodicalId":23685,"journal":{"name":"World journal of emergency medicine","volume":"16 1","pages":"71-73"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11788108/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Azzah S Alharbi, Raghad Hassan Sanyi, Esam I Azhar
{"title":"Bacteria and host: what does this mean for sepsis bottleneck?","authors":"Azzah S Alharbi, Raghad Hassan Sanyi, Esam I Azhar","doi":"10.5847/wjem.j.1920-8642.2025.001","DOIUrl":"10.5847/wjem.j.1920-8642.2025.001","url":null,"abstract":"<p><strong>Background: </strong>Sepsis is a life-threatening inflammatory condition in which the invading pathogen avoids the host's defense mechanisms and continuously stimulates and damages host cells. Consequently, many immune responses initially triggered for protection become harmful because of the failure to restore homeostasis, resulting in ongoing hyperinflammation and immunosuppression.</p><p><strong>Methods: </strong>A literature review was conducted to address bacterial sepsis, describe advances in understanding complex immunological reactions, critically assess diagnostic approaches, and emphasize the importance of studying bacterial bottlenecks in the detection and treatment of sepsis.</p><p><strong>Results: </strong>Diagnosing sepsis via a single laboratory test is not feasible; therefore, multiple key biomarkers are typically monitored, with a focus on trends rather than absolute values. The immediate interpretation of sepsis-associated clinical signs and symptoms, along with the use of specific and sensitive laboratory tests, is crucial for the survival of patients in the early stages. However, long-term mortality associated with sepsis is now recognized, and alongside the progression of this condition, there is an in vivo selection of adapted pathogens.</p><p><strong>Conclusion: </strong>Bacterial sepsis remains a significant cause of mortality across all ages and societies. While substantial progress has been made in understanding the immunological mechanisms underlying the inflammatory response, there is growing recognition that the ongoing host-pathogen interactions, including the emergence of adapted virulent strains, shape both the acute and long-term outcomes in sepsis. This underscores the urgent need for novel high-throughput diagnostic methods and a shift toward more pre-emptive, rather than reactive, treatment strategies in sepsis care.</p>","PeriodicalId":23685,"journal":{"name":"World journal of emergency medicine","volume":"16 1","pages":"10-17"},"PeriodicalIF":2.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11788106/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143190556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}