World journal of emergency medicine最新文献_第10页

Prevention of ventilator-associated pneumonia with inhaled antibiotics. 使用吸入式抗生素预防呼吸机相关肺炎。

IF 2.1 3区医学

World journal of emergency medicine Pub Date : 2024-01-01 DOI: 10.5847/wjem.j.1920-8642.2024.051

Stephan Ehrmann, Jie Li

引用次数: 0

Xuebijing improves intestinal microcirculation dysfunction in septic rats by regulating the VEGF-A/PI3K/Akt signaling pathway. 雪碧通过调节VEGF-A/PI3K/Akt信号通路改善脓毒症大鼠肠道微循环功能障碍

IF 2.1 3区医学

World journal of emergency medicine Pub Date : 2024-01-01 DOI: 10.5847/wjem.j.1920-8642.2024.035

A-Ling Tang, Yan Li, Li-Chao Sun, Xiao-Yu Liu, Nan Gao, Sheng-Tao Yan, Guo-Qiang Zhang

{"title":"Xuebijing improves intestinal microcirculation dysfunction in septic rats by regulating the VEGF-A/PI3K/Akt signaling pathway.","authors":"A-Ling Tang, Yan Li, Li-Chao Sun, Xiao-Yu Liu, Nan Gao, Sheng-Tao Yan, Guo-Qiang Zhang","doi":"10.5847/wjem.j.1920-8642.2024.035","DOIUrl":"10.5847/wjem.j.1920-8642.2024.035","url":null,"abstract":"Background: This study aims to explore whether Xuebijing (XBJ) can improve intestinal microcirculation dysfunction in sepsis and its mechanism.Methods: A rat model of sepsis was established by cecal ligation and puncture (CLP). A total of 30 male SD rats were divided into four groups: sham group, CLP group, XBJ + axitinib group, and XBJ group. XBJ was intraperitoneally injected 2 h before CLP. Hemodynamic data (blood pressure and heart rate) were recorded. The intestinal microcirculation data of the rats were analyzed via microcirculation imaging. Enzyme-linked immunosorbent assay (ELISA) kits were used to detect the serum levels of interleukin-6 (IL-6), C-reactive protein (CRP), and tumor necrosis factor-α (TNF-α) in the rats. Histological analysis and transmission electron microscopy were used to analyze the injury of small intestinal microvascular endothelial cells and small intestinal mucosa in rats. The expression of vascular endothelial growth factor A (VEGF-A), phosphoinositide 3-kinase (PI3K), phosphorylated PI3K (p-PI3K), protein kinase B (Akt), and phosphorylated Akt (p-Akt) in the small intestine was analyzed via Western blotting.Results: XBJ improved intestinal microcirculation dysfunction in septic rats, alleviated the injury of small intestinal microvascular endothelial cells and small intestinal mucosa, and reduced the systemic inflammatory response. Moreover, XBJ upregulated the expression of VEGF-A, p-PI3K/total PI3K, and p-Akt/total Akt in the rat small intestine.Conclusion: XBJ may improve intestinal microcirculation dysfunction in septic rats possibly through the VEGF-A/PI3K/Akt signaling pathway.","PeriodicalId":23685,"journal":{"name":"World journal of emergency medicine","volume":"15 3","pages":"206-213"},"PeriodicalIF":2.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11153371/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141296877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

IF 2.6 3区医学

World journal of emergency medicine Pub Date : 2024-01-01 DOI: 10.5847/wjem.j.1920-8642.2024.086

Ping Gong, Fang Chen, Yonggang Gui, Yanfen Chai, Yi Jiang

引用次数: 0

IF 2.6 3区医学

World journal of emergency medicine Pub Date : 2024-01-01 DOI: 10.5847/wjem.j.1920-8642.2024.043

Jie Er Janice Soo, Yuan Helen Zhang, Gek Hsiang Lim, Fatimah Lateef

{"title":"Bicycle-related traumatic injuries: a retrospective study during COVID-19 pandemic.","authors":"Jie Er Janice Soo, Yuan Helen Zhang, Gek Hsiang Lim, Fatimah Lateef","doi":"10.5847/wjem.j.1920-8642.2024.043","DOIUrl":"https://doi.org/10.5847/wjem.j.1920-8642.2024.043","url":null,"abstract":"Background: This study aimed to review bicycle-related injuries during the COVID-19 pandemic to assist with reinforcement or implementation of new policies for injury prevention.Methods: This is a retrospective descriptive analysis of injuries sustained during cycling for patients 18 years old and above who presented to Singapore General Hospital from January to June 2021. Medical records were reviewed and consolidated. Descriptive analyses were used to summarize patient characteristics, and differences in characteristics subgrouped by triage acuity and discharge status were analyzed.Results: The study included 272 patients with a mean age of 43 years and a male predominance (71.7%). Most presented without referrals (88.2%) and were not conveyed by ambulances (70.6%). Based on acuity category, there were 24 (8.8%) Priority 1 (P1) patients with 7 trauma activations, 174 (64.0%) and 74 (27.2%) P2 and P3 patients respectively. The most common injuries were fractures (34.2%), followed by superficial abrasion/contusion (29.4%) and laceration/wound (19.1%). Thirteen (4.8%) patients experienced head injury and 85 patients (31.3%) were documented to be wearing a helmet. The majority occurred on the roads as traffic accidents (32.7%). Forty-two patients (15.4%) were admitted with a mean length of stay of 4.1 d and 17 (6.3%) undergone surgical procedures. Out of 214 (78.7%) discharged patients, no re-attendances or mortality were observed. In the subgroup analysis, higher acuity patients were generally older, with higher proportions of head injuries leading to admission.Conclusion: Our study highlights significant morbidities in bicycle-related injuries. There is also a high proportion of fractures in the young healthy male population. Injury prevention is paramount and we propose emphasizing helmet use and road user safety.","PeriodicalId":23685,"journal":{"name":"World journal of emergency medicine","volume":"15 4","pages":"256-262"},"PeriodicalIF":2.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11265626/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141761273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aggressive fluid management may be associated with disease progression in suspected sepsis patients admitted to the intensive care unit: a retrospective cohort study. 一项回顾性队列研究：积极输液可能与重症监护病房疑似败血症患者的病情进展有关。

IF 2.1 3区医学

World journal of emergency medicine Pub Date : 2024-01-01 DOI: 10.5847/wjem.j.1920-8642.2024.009

Miao Bian, Zhihao Wang, Yanling Chen, Yue Sun, Hongsen Ji, Yutao Wang, Li Pang

引用次数: 0

Phrenic nerve block: the key to managing acute biliary pain? 膈神经阻滞：控制急性胆道疼痛的关键？

IF 2.1 3区医学

World journal of emergency medicine Pub Date : 2024-01-01 DOI: 10.5847/wjem.j.1920-8642.2024.005

Michael Shalaby, Joshua Luftig

引用次数: 0

Pulmonary rehabilitation protocols in urgent lung transplantation patients. 紧急肺移植患者的肺康复方案。

IF 2.1 3区医学

World journal of emergency medicine Pub Date : 2024-01-01 DOI: 10.5847/wjem.j.1920-8642.2024.015

Fei Zeng, Lingyun Cai, Luyao Guo, Meijuan Lan, Jiangshuyuan Liang, Peipei Gu

{"title":"Pulmonary rehabilitation protocols in urgent lung transplantation patients.","authors":"Fei Zeng, Lingyun Cai, Luyao Guo, Meijuan Lan, Jiangshuyuan Liang, Peipei Gu","doi":"10.5847/wjem.j.1920-8642.2024.015","DOIUrl":"10.5847/wjem.j.1920-8642.2024.015","url":null,"abstract":"Background: Prolonged invasive respiratory support and extracorporeal membrane oxygenation (ECMO) in patients requiring urgent lung transplantation (ULTx) present significant challenges to clinical practice due to severe underlying diseases and complex conditions. The aim of the study was to report the clinical outcomes of patients who received ULTx and followed the perioperative rehabilitation protocol implemented in a lung transplant center.Methods: A retrospective analysis was conducted in ULTx patients who required preoperative invasive mechanical ventilation (IMV) and ECMO between January 2018 and January 2023. Data were retrieved from electronic medical records at our lung transplant center.Results: Fourteen patients (mean age 57.43±10.97 years; 12 males, 2 females) underwent ULTx with bridging ECMO and IMV. The mean body mass index was 23.94±3.33 kg/m², and the mean Acute Physiology and Chronic Health Evaluation (APACHE) II score was 21.50±3.96. The Nutritional Risk Screening 2002 (NRS 2002) scores were ≥3. ULTx was performed after an 8.5-day waiting period (interquartile interval [IQR] 5.0-26.5 d). Following the surgeries, the average lengths of ECMO and IMV were 1.0 (IQR 1.0-2.0) d and 5.0 (IQR 3.0-7.3) d, respectively. The total length of hospital stay was 60.1±30.8 d, with an average intensive care unit stay of 38.3±22.9 d and post-operative hospitalization stay of 45.8±26.1 d. Two patients died within 30 d after ULTx, with a 30-day survival rate of 85.71%.Conclusion: Patients receiving ULTx showed an acceptable short-term survival rate, validating the practicality and safety of the treatment protocols implemented in our center.","PeriodicalId":23685,"journal":{"name":"World journal of emergency medicine","volume":"15 1","pages":"47-51"},"PeriodicalIF":2.1,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10765079/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139378274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Total suprarenal aortic occlusion with cardiac disease: a case series of three cases. 伴有心脏病的肾上主动脉全闭塞：三例病例系列。

IF 2.1 3区医学

World journal of emergency medicine Pub Date : 2024-01-01 DOI: 10.5847/wjem.j.1920-8642.2024.004

Yuanli Lei, Jiaozhen Chen, Qin Chen, Jiana Yin, Weijia Huang, Wenxing Song, Shouquan Chen

引用次数: 0

Esophageal inserted subclavian catheter: a rare complication. 食管插入锁骨下导管：一种罕见的并发症。

IF 2.1 3区医学

World journal of emergency medicine Pub Date : 2024-01-01 DOI: 10.5847/wjem.j.1920-8642.2024.036

Dilber Üçöz Kocaşaban, Sertaç Güler

引用次数: 0

The association between C-reactive protein to albumin ratio and 6-month neurological outcome in patients with in-hospital cardiac arrest. 院内心脏骤停患者的 C 反应蛋白与白蛋白比值与 6 个月神经功能预后之间的关系。

IF 2.1 3区医学

World journal of emergency medicine Pub Date : 2024-01-01 DOI: 10.5847/wjem.j.1920-8642.2024.037

Ji Ho Lee, Dong Hun Lee, Byung Kook Lee, Seok Jin Ryu

引用次数: 0