Vector borne and zoonotic diseases最新文献_第8页

Molecular Identification of Host Blood Meal from Phlebotomine Sandflies (Diptera: Psychodidae) from Kerala, India. 印度喀拉拉邦沙蝇（双翅目：灵蝇科）寄主血餐的分子鉴定

IF 1.8 4区医学

Vector borne and zoonotic diseases Pub Date : 2024-12-01 Epub Date: 2024-07-27 DOI: 10.1089/vbz.2023.0168

Harish Kumar Shah, P A Fathima, P M Ajithlal, Jessu S Mathew, Prasanta Saini

{"title":"Molecular Identification of Host Blood Meal from Phlebotomine Sandflies (Diptera: Psychodidae) from Kerala, India.","authors":"Harish Kumar Shah, P A Fathima, P M Ajithlal, Jessu S Mathew, Prasanta Saini","doi":"10.1089/vbz.2023.0168","DOIUrl":"10.1089/vbz.2023.0168","url":null,"abstract":"Background: Female phlebotomine sandflies serve as vectors for the transmission of Leishmania parasites, perpetuating an enzootic cycle by disseminating between sylvatic and domestic animals. Humans form a part of this cycle because the sandflies search for a blood source required for egg development. The present study aimed to identify the feeding preferences of different sandfly fauna from six districts of Kerala, India, using molecular tools. Materials and Methods: An entomological survey was conducted during 2021-2023 in Kollam, Kottayam, Thiruvananthapuram, Thrissur, Malappuram, and Palakkad. Both indoor and outdoor habitats were targeted from sandfly collection using different standard tools and methods. Sandflies were identified using standard taxonomic keys, and DNA was extracted from blood meal collected from sandflies. Results: A total of 7366 sandfly specimens were collected during the study period, which belonged to three different genera and 19 species. Blood source was successfully identified from 119 sandflies revealing that the Sergentomyia genus preferably fed on small reptiles and amphibians, whereas Phlebotomus genus was found to mainly feed on mammalian and avian blood. Sergentomyia zeylanica was an exception, as it primarily fed on mammalian blood sources. Interestingly, humans were the second feeding source for Phlebotomus species, which are the proven vectors. Conclusion: Comprehending the feeding patterns of sandflies is crucial, not just for public health but also for obtaining insights into the ecological dynamics between vectors and hosts, ultimately enabling more efficient strategies for disease control and prevention.","PeriodicalId":23683,"journal":{"name":"Vector borne and zoonotic diseases","volume":" ","pages":"808-816"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141789180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Commercial Enzyme-Linked Immunosorbent Assay Kit Is Useful for Detection of Recombinant and Secretory Nonstructural-1 Protein Antigen of Dengue Virus. 商用酶联免疫吸附试剂盒可用于检测登革病毒重组蛋白和分泌型非结构-1 蛋白抗原

IF 1.8 4区医学

Vector borne and zoonotic diseases Pub Date : 2024-12-01 Epub Date: 2024-08-12 DOI: 10.1089/vbz.2024.0009

Philip Raj Abraham, Tharini Gopinath, Akash Dhotre, Ashwani Kumar

{"title":"Commercial Enzyme-Linked Immunosorbent Assay Kit Is Useful for Detection of Recombinant and Secretory Nonstructural-1 Protein Antigen of Dengue Virus.","authors":"Philip Raj Abraham, Tharini Gopinath, Akash Dhotre, Ashwani Kumar","doi":"10.1089/vbz.2024.0009","DOIUrl":"10.1089/vbz.2024.0009","url":null,"abstract":"Background: Dengue is a mosquito-borne tropical disease, caused by the Dengue virus (DENV). It has become a severe problem and is a rising threat to public health. In this study, we have evaluated commercial Merilisa i Dengue NS1 Antigen kit (Meril LifeSciences India Pvt. Ltd.) to detect recombinant dengue virus 2 NS1 antigen (rDNS1Ag) and secreted forms of NS1 antigen (sDNS1Ag). Methods: To determine the detection limit of the kit, 100 nanogram (ng) to 0.001 ng rDNS1Ag was tested. The sensitivity and specificity of the kit was determined using recombinant NS1 antigens of all serotypes of DENV and other flaviviruses. For testing sDNS1Ag, the culture supernatant of the Vero cell lines infected with DENV-2 was tested. Further, a spiking experiment was carried out to check the sensitivity of the kit to detect rDNS1Ag in the pools of Aedes aegypti mosquitoes. Results: It was observed that the kit can detect the rDNS1Ag at 1 ng concentration. The kit was sensitive to detect NS1 antigen of DENV-1, DENV-2 and DENV-3 serotypes and specific for detection of only DNS1Ag as it did not cross-react with NS1 antigen of flaviviruses. The kit was sensitive to detect rDNS1Ag in the mosquito pools as well. In addition, the kit was able to detect the sDNS1Ag in Vero cell culture supernatant. Conclusions: Overall, we observed that the Merilisa i Dengue NS1 Ag kit is sensitive and specific for the detection of DNS1Ag both in recombinant and secretory forms.","PeriodicalId":23683,"journal":{"name":"Vector borne and zoonotic diseases","volume":" ","pages":"817-825"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141971956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular Detection of Coxiella burnetii in Vaginal Swab Samples from Sheep That Aborted. 流产绵羊阴道拭子样本中燃烧性柯西氏菌的分子检测

IF 1.8 4区医学

Vector borne and zoonotic diseases Pub Date : 2024-12-01 Epub Date: 2024-07-11 DOI: 10.1089/vbz.2023.0153

Oliver Sánchez-Rodríguez, Erika G Palomares-Resendiz, Efrén Díaz-Aparicio, Beatriz Arellano-Reynoso, Luary C Martínez-Chavarría, Guadalupe Martínez-Serrano, Rigoberto Hernández-Castro

{"title":"Molecular Detection of Coxiella burnetii in Vaginal Swab Samples from Sheep That Aborted.","authors":"Oliver Sánchez-Rodríguez, Erika G Palomares-Resendiz, Efrén Díaz-Aparicio, Beatriz Arellano-Reynoso, Luary C Martínez-Chavarría, Guadalupe Martínez-Serrano, Rigoberto Hernández-Castro","doi":"10.1089/vbz.2023.0153","DOIUrl":"10.1089/vbz.2023.0153","url":null,"abstract":"Background: Coxiella burnetii, an obligate intracellular bacterium, is the etiological agent of Q fever in humans and one of the causes of abortion in small ruminants. Although coxiellosis is considered an exotic disease, there are a few reports in Mexico. Methods: The objective of this work was to determine the presence of C. burnetii DNA in vaginal samples from sheep that presented abortion and ram semen. A total of 180 vaginal exudate samples and 20 semen samples were obtained from five Central and Southern States of Mexico. Total DNA was extracted from vaginal swabs and C. burnetii was identified by PCR amplification and sequencing of the IS1111 insertion sequence. Results and Conclusion: In total, 110 (110/180) vaginal samples and 12 (12/20) semen samples were positive for C. burnetii. This is the first report of C. burnetii in sheep that aborted and in ram semen in Mexico.","PeriodicalId":23683,"journal":{"name":"Vector borne and zoonotic diseases","volume":" ","pages":"838-841"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141580960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction of: "Alexandra Bishop, Jennifer Borski, Hsiao-Hsuan Wang, Taylor G. Donaldson, Avery Michalk, Annie Montgomery, Samantha Heldman, Michael Mogg, Zakary Derouen, William E. Grant, and Pete D. Teel. Increasing Incidence of Spotted Fever Group Rickettsioses in the United States, 2010-2018.Vector-Borne and Zoonotic Diseases. Sep 2022. 491-497." doi: 10.1089/vbz.2022.0021. 更正："Alexandra Bishop, Jennifer Borski, Hsiaoo-Hsuan Wang, Taylor G. Donaldson, Avery Michalk, Annie Montgomery, Samantha Heldman, Michael Mogg, Zakary Derouen, William E. Grant, and Pete D. Teel.2010-2018年美国斑点热群立克次体病发病率的增加.病媒与人畜共患疾病.9月 2022。491-497." doi: 10.1089/Vbz.2022.0021.

IF 1.8 4区医学

Vector borne and zoonotic diseases Pub Date : 2024-12-01 Epub Date: 2024-07-16 DOI: 10.1089/vbz.2024.0059

Hsiao-Hsuan Wang, Alexandra Bishop, Jennifer Borski, Taylor G Donaldson, Avery Michalk, Annie Montgomery, Samantha Heldman, Michael Mogg, Zakary Derouen, William E Grant, Pete D Teel

引用次数: 0

Frequency of Leptospira in the Blood of Patients with Fever of Unknown Origin in Sinaloa, Mexico. 墨西哥锡那罗亚不明原因发热患者血液中钩端螺旋体的频率。

IF 1.8 4区医学

Vector borne and zoonotic diseases Pub Date : 2024-12-01 Epub Date: 2024-07-18 DOI: 10.1089/vbz.2024.0001

Rogelio Lagarde-Guerrero, María de Jesús Navarro-Arias, Sergio Alonso Duran-Pérez, Ignacio Osuna-Ramírez, Lorenzo Ulises Osuna-Martínez, Elizabeth Gonzáles-Durán, José Guadalupe Rendon-Maldonado

{"title":"Frequency of Leptospira in the Blood of Patients with Fever of Unknown Origin in Sinaloa, Mexico.","authors":"Rogelio Lagarde-Guerrero, María de Jesús Navarro-Arias, Sergio Alonso Duran-Pérez, Ignacio Osuna-Ramírez, Lorenzo Ulises Osuna-Martínez, Elizabeth Gonzáles-Durán, José Guadalupe Rendon-Maldonado","doi":"10.1089/vbz.2024.0001","DOIUrl":"10.1089/vbz.2024.0001","url":null,"abstract":"Background: Leptospira is a genus of bacteria that causes the zoonotic disease known as leptospirosis, which mainly affects countries with tropical and subtropical climates. Its prevalence may be underestimated because the initial stage of the infection is characterized by presenting a febrile condition that is easily confused with other diseases, such as dengue. This work reports the frequency of leptospirosis in the blood of patients with febrile symptoms of unknown origin. Materials and Methods: A total of 218 peripheral blood samples were analyzed from volunteer participants from Culiacan Sinaloa in June 2019, one half corresponded to patients with undiagnosed febrile symptoms and the other half to asymptomatic volunteers. Data collected included the age and sex of the participants. Leptospira was detected by qPCR using a fragment of the lipL32 gene from the bacteria's genome as a target. Fisher's exact test was used as a statistical method to estimate the relationship between the infection and the data collected. Results: The study group comprised 134 female and 84 male patients ranging from ages 1 to 92 years, averaging 41 years. In this study, Leptospira infection was identified in the blood of 22/218 participating volunteers (10.09%), of which 20/109 (18.34%) presented febrile symptoms, whereas 2/109 (1.83%) were asymptomatic. The most affected participants were women with ages between 27 and 59 years. However, the analysis of the relationship between infection and the variables studied did not show statistical significance. Conclusions: Leptospirosis was detected in blood samples from patients with undiagnosed febrile illness and asymptomatic symptoms in Sinaloa. The lipL32 gene is useful as a target in identifying Leptospira in human blood in the acute phase of the disease.","PeriodicalId":23683,"journal":{"name":"Vector borne and zoonotic diseases","volume":" ","pages":"802-807"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141634668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lyme Disease Confirmatory Western Blot Is Redundant for Screen Negative Samples in Low Endemic Areas, British Columbia, Canada. 在加拿大不列颠哥伦比亚省的低流行区，莱姆病确诊 Western Blot 对于筛查阴性样本是多余的。

IF 1.8 4区医学

Vector borne and zoonotic diseases Pub Date : 2024-12-01 Epub Date: 2024-07-23 DOI: 10.1089/vbz.2024.0042

Emily Kon, Hansi Adikari, Yvonne Simpson, Quantine Wong, Jonathan Laley, Navdeep Chahil, Muhammad Morshed

{"title":"Lyme Disease Confirmatory Western Blot Is Redundant for Screen Negative Samples in Low Endemic Areas, British Columbia, Canada.","authors":"Emily Kon, Hansi Adikari, Yvonne Simpson, Quantine Wong, Jonathan Laley, Navdeep Chahil, Muhammad Morshed","doi":"10.1089/vbz.2024.0042","DOIUrl":"10.1089/vbz.2024.0042","url":null,"abstract":"Background: Borrelia burgdorferi sensu stricto is the causative agent of Lyme disease (LD). Possible early symptoms include flu-like symptoms and erythema migrans and later, the risk of disruption of the nervous system, joints, and heart. A two-tiered testing method is employed for serological diagnostics. The Public Health Agency of Canada guidelines recommend that samples tested negative on first-tiered test need not be confirmed by second-tiered test. Due to the challenging nature of diagnosis leading to misconceptions among physicians about false negatives, confirmatory testing is requested despite the initial negative result. Methods: Hundred screen-negative Lyme patient samples from 2007 to 2016 were tested by Western blot (WB) second-tiered confirmatory test upon physician's request in British Columbia to study the first-tiered screening test sufficiency. Results: Those negative for first-tiered enzyme-linked immunosorbent assay were also negative by WB. Conclusion: Results demonstrate that confirmatory testing is not necessary on screen-negative samples. Hence, first-tiered test is sufficient to rule out LD.","PeriodicalId":23683,"journal":{"name":"Vector borne and zoonotic diseases","volume":" ","pages":"835-837"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141752855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Serological Evidence of Bactrian Camel Infection with Tamdy Virus, Xinjiang, China. 中国新疆双峰驼感染 Tamdy 病毒的血清学证据。

IF 1.8 4区医学

Vector borne and zoonotic diseases Pub Date : 2024-12-01 Epub Date: 2024-07-27 DOI: 10.1089/vbz.2024.0019

Mingxue Cui, Yuhai Bi, Moujian Guo, Michael J Carr, Weifeng Shi, Zhenghai Ma, Hong Zhou

{"title":"Serological Evidence of Bactrian Camel Infection with Tamdy Virus, Xinjiang, China.","authors":"Mingxue Cui, Yuhai Bi, Moujian Guo, Michael J Carr, Weifeng Shi, Zhenghai Ma, Hong Zhou","doi":"10.1089/vbz.2024.0019","DOIUrl":"10.1089/vbz.2024.0019","url":null,"abstract":"Background: Tamdy Virus (TAMV) is a pathogenic nairovirus widely distributed in central Asia and northwestern China. However, the host range of TAMV remains unclear, which limits our understanding the transmission cycle and cross-species patterns of this virus. Materials and Methods: A total of 160 serum samples were collected from livestock animals of camels, cattle, and sheep in Xinjiang, China between 2018 and 2021. An indirect immunofluorescence assay for TAMV were developed in this study, and have been employed to test TAMV-specific antibodies in these serum samples. Results: TAMV IgG antibody was detectable in camel sera collected from Urumqi in 2018 (6/17, 35%) and also from the Alertai Region in 2021 (1/8, 12.5%). Conclusion: The serological results in this study provide the first evidence that TAMV is able to infect camels and that the pathogen is circulating in different regions of Xinjiang. These findings highlight the need to further increase clinical and epidemiological surveillance of TAMV in humans and livestock in northwestern China.","PeriodicalId":23683,"journal":{"name":"Vector borne and zoonotic diseases","volume":" ","pages":"842-845"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141789181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence, Isolation, and Molecular Characterization of Severe Fever with Thrombocytopenia Syndrome Virus in Cattle from the Republic of Korea. 大韩民国牛群中严重发热伴血小板减少综合征病毒的流行、分离和分子特征。

IF 1.8 4区医学

Vector borne and zoonotic diseases Pub Date : 2024-12-01 Epub Date: 2024-07-19 DOI: 10.1089/vbz.2024.0008

Jeong-Byoung Chae, Ji-Min Rim, Sun-Woo Han, Yoon-Kyoung Cho, Jun-Gu Kang, Joon-Seok Chae

{"title":"Prevalence, Isolation, and Molecular Characterization of Severe Fever with Thrombocytopenia Syndrome Virus in Cattle from the Republic of Korea.","authors":"Jeong-Byoung Chae, Ji-Min Rim, Sun-Woo Han, Yoon-Kyoung Cho, Jun-Gu Kang, Joon-Seok Chae","doi":"10.1089/vbz.2024.0008","DOIUrl":"10.1089/vbz.2024.0008","url":null,"abstract":"Background: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne disease caused by Bandavirus dabieense. Initially identified in China, this disease has spread throughout Asian countries via tick bites and animal-to-human transmission. However, reports of the prevalence of SFTS virus (SFTSV) in cattle in Korea are lacking. This study aimed to investigate SFTSV infections in grazing cattle in the Republic of Korea (ROK). Materials and Methods: In total, 845 grazing cattle serum samples were collected over 2 years (2019 and 2020) in the ROK, and viral RNA was extracted using a kit. One-step RT-nested PCR was performed to amplify the S-segment of SFTSV. Positive serum samples were used to isolate SFTSV in Vero E6 cells, and the full sequences were analyzed. A phylogenetic tree was constructed using the maximum-likelihood method with MEGA X. In addition, immunoglobulin G antibodies against SFTSV were investigated using an enzyme-linked immunosorbent assay. Results: Here, 4.0% of serum samples (34/845) were positive for SFTSV S-segments, and one virus isolate was cultured in Vero E6 cells. Phylogenetic analysis based on the partial S-segment classified 4 SFTSV isolates as the B-2 genotype, 9 as the B-3 genotype, 18 as an unclassified B genotype, and 3 as the D genotype. One cultured virus was classified as the B-2 genotype based on SFTSV L-, M-, and S-segments. Antibody detection results showed that 21.1% of serum samples (161/763) were positive for SFTSV. Conclusion: To the best of our knowledge, this is the first study performed to identify the prevalence of SFTSV in grazing cattle in the ROK. Our findings indicate the necessity for more intensive and continuous SFTSV monitoring, not only in cattle but also in other animals, to comprehend the genetic diversity of the virus and its potential eco-epidemiological impact on human health.","PeriodicalId":23683,"journal":{"name":"Vector borne and zoonotic diseases","volume":" ","pages":"826-834"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141727902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction of: "Michael Mogg, Hsiao-Hsuan Wang, Adam Baker, Zakary Derouen, Jennifer Borski, and William E. Grant. Increased Incidence of Ehrlichia chaffeensis Infections in the United States, 2012 Through 2016. Vector-Borne and Zoonotic Diseases. Jul 2020. 547-550." doi: 10.1089/Vbz.2019.2595. 更正："Michael Mogg、Hxiao-Hsuan Wang、Adam Baker、Zakary Derouen、Jennifer Borski 和 William E. Grant。2012年至2016年美国埃立卡氏虫感染发病率增加》。病媒传染病和人畜共患病。2020年7月。547-550."Http://Doi.org/10.1089/Vbz.2019.2595.

IF 1.8 4区医学

Vector borne and zoonotic diseases Pub Date : 2024-12-01 Epub Date: 2024-07-17 DOI: 10.1089/vbz.2024.0058

Hsiao-Hsuan Wang, Michael Mogg, Adam Baker, Zakary Derouen, Jennifer Borski, William E Grant

引用次数: 0

A Case Series on Spotted Fever and Typhus Fever Seropositivity at National Center for Disease Control and Epidemiological Perspective. 国家疾病控制中心斑疹热和斑疹伤寒血清阳性病例系列及流行病学视角。

IF 1.8 4区医学

Vector borne and zoonotic diseases Pub Date : 2024-11-01 Epub Date: 2024-06-17 DOI: 10.1089/vbz.2024.0024

Stuti Gupta, Cordelia Siddiqui, Prakriti Sharma, Jyoti Kataria, Sharda Singh, Vishesh Sood, Monil Singhai

{"title":"A Case Series on Spotted Fever and Typhus Fever Seropositivity at National Center for Disease Control and Epidemiological Perspective.","authors":"Stuti Gupta, Cordelia Siddiqui, Prakriti Sharma, Jyoti Kataria, Sharda Singh, Vishesh Sood, Monil Singhai","doi":"10.1089/vbz.2024.0024","DOIUrl":"10.1089/vbz.2024.0024","url":null,"abstract":"Background: The rickettsioses, except for typhus fever and scrub typhus (ST), were not really recognized as distinct clinical entities until the early 20th century. Only when specific rickettsial serologic testing was introduced in the 1940s could the precise etiologies of various rickettsial diseases (RDs) be determined with certainty. Although ST is a well- recognized zoonotic disease entity, but non-scrub typhus rickettsial infection like spotted fever group and typhus group are not well studied in India and are still underestimated. Methods: We report cases who had shown seropositivity of spotted fever and typhus fever RD in IgM and IgG ELISA whose samples were referred from various hospitals of Delhi/National Capital Region in which clinicians had strong suspicion of rickettsiosis other than ST or Weil-Felix test found positive for any of the OX2, 19, and K antigens. Results: We reported 18 cases of SFG and TGRD with mostly cases presented with fever followed by hepato-intestinal symptoms. Conclusion: The vast variability and nonspecific presentation of rickettsiosis in spotted and typhus fever at times have often made it difficult to diagnose clinically. Prompt antibiotic therapy shortens the course of the disease, lowers the risk of complications, and in turn, reduces morbidity and mortality owing to RDs. There is a distinct need for physicians and health care workers at all levels of care in India to be aware of the clinical features, available diagnostic tests and their interpretation, and the therapy for these infections.","PeriodicalId":23683,"journal":{"name":"Vector borne and zoonotic diseases","volume":" ","pages":"784-787"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141421174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0