O B Olaoye, E A Ajayi, O A Busari, O E Ojo, A O Adeoti, O Adewuya
{"title":"Prevalence of Acute Heart Failure and The Role of N-Terminal Prohormone Brain Natriuretic Peptide among Acute Dyspnoeic Patients in the Emergency Room.","authors":"O B Olaoye, E A Ajayi, O A Busari, O E Ojo, A O Adeoti, O Adewuya","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Acute dyspnoea (AD) is one of the most common presentations in the emergency room (ER). Its myriads of confusing differentials which include acute heart failure (AHF) has significant mortality and morbidity, and specific mode of treatment. The measurement of NT-proBNP among AD patients when AHF is being suspected will aid early diagnosis, treatment and improve outcomes.</p><p><strong>Objective: </strong>To estimate the prevalence of AHF and usefulness of NT-proBNP among AD patients at the Ekiti State University Teaching Hospital's (EKSUTH) ER.</p><p><strong>Method: </strong>This was a cross-sectional study. Persons aged 18 years or older with AD in the ER of the EKSUTH, Nigeria were recruited. The patients were sub-categorized into heart failure as a cause of AD (HFAD) and non-heart failure as a cause of AD (nHFAD). NT-proBNP was assayed alongside ECHO parameters for the participants.</p><p><strong>Results: </strong>There were 143 cases and 72 matched controls. The mean age of patients was 56.96± 13.5yrs while that of the controls was 56.17± 14.5yrs (p=0.685). Seventy-seven patients (54%) had AHF while the remaining 46% were dyspnoea of non-cardiac origin. Pneumonia, COPD, asthma and PE accounted for 33.57%, 8.40%, 2.80% and 1.40% respectively. The median NT-proBNP level was higher (p<0.001) in the AD patients compared to controls; 592.0 vs 37.50 pg/mL. The median NT-proBNP level was higher in the HFAD group than those with nHFAD and the controls (2885.40 vs. 128.70 and 37.50 pg/mL, P<0.001). NT-proBNP levels inversely and moderately correlated with ejection fraction (EF) (ρ= 0.68, p<0.001). It directly and moderately correlated with HF severity using the NYHA functional classification (ρ=0.50, p=0.017). An age-independent NT-proBNP cut-point level of 305 pg/mL recorded 93.5%, 88.3%, 45.3% and 99.2% for sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) respectively.</p><p><strong>Conclusion: </strong>AHF is the major cause of AD in ER. In AHF patients, NT-proBNP correlated inversely well with EF and NYHA functional classification, and has high sensitivity and NPV.</p>","PeriodicalId":23680,"journal":{"name":"West African journal of medicine","volume":"42 5","pages":"394-404"},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145239857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Predictors of Sleep Quality in Older Persons Attending the Outpatient Clinics in a Tertiary Hospital in Nigeria.","authors":"O A Akinola, E A Etukumana, U M Morgan","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Good quality sleep is critical to human functioning as decline in sleep quality has been linked with health issues. One of the factors that has been identified with decline in sleep quality is increasing age, making older persons at risk of significant deleterious consequences on their physical, social, and mental spheres of well-being when they have poor sleep quality.</p><p><strong>Objectives: </strong>This study aimed at determining the predictors of sleep quality among older persons aged 60 years and above attending the outpatient clinics of a tertiary hospital in Uyo, South-South Nigeria with a view to suggesting appropriate recommendations for health improvement of participants and clinical practice, where necessary.</p><p><strong>Methodology and methods: </strong>This was a cross-sectional study involving two hundred and fourteen (214) respondents. Those who met the inclusion criteria were interviewed with the aid of a semi- structured questionnaire containing items on socio-demographic characteristics, clinical data, and items from the Pittsburgh sleep quality index. Data was analysed using Epi info® version 3.5.1.</p><p><strong>Results: </strong>Of the 214 respondents recruited, the prevalence of good sleep quality was 63.1% with a higher rate of poor sleep quality observed in males (57%). Factors affecting sleep quality after bivariate analysis in this study were age group (70-74 years), polygamous family type, significant stress, sleep problems, chronic medical illness, routine medication, high blood pressure, overweight and obesity. However, when multiple logistic regression was done on these factors, family type, sleep problems, and chronic medical illness were still statistically significant.</p><p><strong>Conclusions: </strong>More than one-third of the older persons had poor quality of sleep in this study, and the predictors of sleep quality were family type (polygamous), sleep problems, and chronic medical illness. Therefore, there is need for a careful routine assessment of sleep among older persons and this should include comprehensive sleep history as well as evaluation and treatment of various co-morbidities in order to improve sleep quality among them.</p>","PeriodicalId":23680,"journal":{"name":"West African journal of medicine","volume":"42 5","pages":"405-412"},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145239887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T Kuku-Kuye, A M Olumodeji, O C Oyebode, A K Adefemi, M O Adedeji, Y A Oshodi, T A Ottun, K A Rabiu
{"title":"Antepartum Risk Stratification and Its Influence on Labour Interventions and Outcomes: A Retrospective Cohort Study.","authors":"T Kuku-Kuye, A M Olumodeji, O C Oyebode, A K Adefemi, M O Adedeji, Y A Oshodi, T A Ottun, K A Rabiu","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Early identification of risk factors in pregnancy is essential to improving maternal and neonatal outcomes. High-risk pregnancies, characterized by maternal or fetal factors that increase the likelihood of complications, contribute significantly to maternal mortality, particularly in low- and middle-income countries (LMICs). This study examines the influence of antepartum risk stratification on labour interventions and outcomes among women in Lagos, Nigeria.</p><p><strong>Methods: </strong>This retrospective cohort study included 507 women admitted to the labour ward at Lagos State University Teaching Hospital (LASUTH) from May 2019 to April 2022. Participants were classified as low-risk or high-risk based on antenatal clinical profiles, including sociodemographic, obstetric, and medical factors. Outcomes were assessed based on labour interventions (induction, augmentation, mode of delivery) and neonatal outcomes (APGAR scores, NICU admissions). Data was analyzed using descriptive statistics, chi-square tests, and logistic regression to identify factors associated with high-risk classification and outcomes.</p><p><strong>Results: </strong>High-risk pregnancies constituted 17.6% of the cohort and were associated with younger maternal age, nulliparity, and higher antenatal care utilization. High-risk women had significantly higher rates of induction (14.6% vs. 1.2%), oxytocin augmentation (27% vs. 5.3%), and emergency cesarean delivery (39.3% vs. 23.4%). Neonates of high-risk pregnancies had lower APGAR scores and higher NICU admissions (25.8% vs. 3.8%, p < 0.001). Increased ANC attendance was significantly associated with high-risk classification.</p><p><strong>Conclusion: </strong>High-risk pregnancies are associated with increased maternal and neonatal complications, highlighting the importance of early risk stratification and adherence to WHO guidelines for adequate antenatal care. Strengthening ANC services and timely interventions can improve outcomes in LMICs.</p>","PeriodicalId":23680,"journal":{"name":"West African journal of medicine","volume":"42 5","pages":"346-352"},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145233573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C G Okwuonu, G O Achor, N M Erondu, O Ekwenna, S Alhassan, C Abali, E Okam, C Ralph-Iheke, P Ngwu, I I Chukwuonye, A Onyebuchi, R A Balogun
{"title":"Performance and Outcome of Pioneering Kidney Transplantation in a Resource-Constrained Setting in Southeast Nigeria.","authors":"C G Okwuonu, G O Achor, N M Erondu, O Ekwenna, S Alhassan, C Abali, E Okam, C Ralph-Iheke, P Ngwu, I I Chukwuonye, A Onyebuchi, R A Balogun","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Kidney transplantation is the optimal treatment for improving survival and quality of life for patients with end-stage kidney disease. There was no kidney transplant surgery and acute transplant care services in Southeast Nigeria until 2017 when our institution commenced kidney transplant surgery and acute transplant care. This study aims to share our first eight year experience including graft and patient outcome.</p><p><strong>Objectives: </strong>To obtain the transplant rate, short and long term complications and the graft and patient survival over an eight year period in a tertiary hospital in Southeast Nigeria.</p><p><strong>Method: </strong>A retrospective review of the transplant register for patients referred to the kidney transplant unit over an eight year period from January 2017 to January 2025.</p><p><strong>Result: </strong>Complete data for ninety-three patients were analyzed. Out of these, twelve were transplanted giving a transplantion rate of 13%. Financial constraint is the leading reason (40%) for failure to get a kidney transplant done. Hypertension, hyperkalemia, anemia and urinary tract infection were the leading acute complications encountered while cytomegalovirus infection, recurrence of native disease, chronic graft loss and death were the major long term complications. The three-month, one-year, three-year and five-year patient survival in our program were 100%, 90%, 80% and 80% respectively while the graft survival were 90%, 90%, 70% and 60% respectively.</p><p><strong>Conclusion: </strong>The transplant conversion rate is low and a review of atient selection criteria will improve access kidney transplant. Acute complications were treatable in most cases. The patient and graft outcomes appear similar with other centres in Nigeria.</p>","PeriodicalId":23680,"journal":{"name":"West African journal of medicine","volume":"42 5","pages":"413-418"},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145239740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
F O Wuraola, A A Aderounmu, J Jackman, B Yibrehu, O Olasehinde, M Ogunyemi, A O Adisa, T P Kingham, I O Alatise
{"title":"\"Life without an Anus\": Experience of Cancer Patients Living with Colostomy in South West Nigeria.","authors":"F O Wuraola, A A Aderounmu, J Jackman, B Yibrehu, O Olasehinde, M Ogunyemi, A O Adisa, T P Kingham, I O Alatise","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>As the incidence of colorectal cancer increases in Nigeria, more patients will get colostomies. Previous studies of patients with colostomies in other African countries have reported significant decreases in quality of life. Understanding the experiences of Nigerian patients is crucial for designing interventions that ensure patients can maintain a high quality of life after colostomy. This study aims to explore the impact of colostomy on the quality of life of Nigerian patients.</p><p><strong>Methods: </strong>Between August and December 2022, 16 in-depth interviews were conducted with patients who had undergone a colostomy for at least six months. Patients were identified through an institutional database of colorectal cancer patients at Obafemi Awolowo University Teaching Hospital in Southwest Nigeria.</p><p><strong>Results: </strong>Patients overwhelmingly reported life-altering challenges related to their colostomy. Some of the most commonly reported challenges included social isolation, financial constraints, sexual dissatisfaction, and altered self-image. Patients also reported that they did not understand until after surgery what it would be like to live with a colostomy.</p><p><strong>Conclusion: </strong>As the number of cancer patients with colostomies increases in Nigeria, it is important to address the social and financial barriers that patients face after having a colostomy.</p>","PeriodicalId":23680,"journal":{"name":"West African journal of medicine","volume":"42 5","pages":"364-371"},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145233615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H S Akogwu, N D Baamlong, B A Grema, A S Adebisi, A A Kaoje, A Abubakar
{"title":"Clinical Characteristics and Predictors of Depression among the Older Adults Attending the Family Medicine Clinic of Usmanu Danfodiyo University Teaching Hospital Sokoto in Northwestern Nigeria.","authors":"H S Akogwu, N D Baamlong, B A Grema, A S Adebisi, A A Kaoje, A Abubakar","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Depression represents a major international public health problem for both developed and developing countries. It is associated with increased risk of morbidity, suicide, decreased physical, cognitive and social function, and greater self-neglect, which in turn is associated with increased mortality.</p><p><strong>Objective: </strong>The study objective was to determine the clinical characteristics and predictors of depression among the elderly attending the family medicine clinic of Usmanu Danfodiyo University Teaching Hospital, Sokoto, Northwestern Nigeria.</p><p><strong>Methodology: </strong>The study was a hospital-based cross-sectional study of 391 elderly participants in the family medicine clinic of Usmanu Danfodiyo University Teaching Hospital, recruited through systematic sampling technique. Data was collected using a pre-tested, structured interviewer-administered questionnaire, and Folstein (MMSE). The GDS-30 was used to screen for depression. BMI was calculated and data analyzed using SPSS version 20. Test of associations was done using the Chi-square test, and logistic regression was done; P < 0.05 was considered statistically significant.</p><p><strong>Results: </strong>The prevalence of depression among the elderly was found to be 41.2%. Following logistic regression, being married (OR=0.559, 95% CI=0.321-0.974), bereavement in the last six months (OR=2.35, 95% CI=1.138- 4.480), poor subjective health status (OR=0.141, 95% CI=0.057-0.348), and abnormal BMI (OR=0.425, 95% CI=0.221-0.818) were found to be predictors of elderly depression in the study.</p><p><strong>Conclusion: </strong>The prevalence of depression among older adults was high, and the study recommends early screening, detection and management of risk factors of depressive disorder in older adults by primary care physicians.</p>","PeriodicalId":23680,"journal":{"name":"West African journal of medicine","volume":"42 5","pages":"353-363"},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145233524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Outcome of Laparoscopic Cholecystectomy at King Khalid Hospital, Hail, Saudi Arabia.","authors":"R A S Altwiher, N J Nwashilli, A S Alzaid","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Laparoscopic cholecystectomy has evolved to become the gold standard treatment of calculous and acalculous cholecystitis.</p><p><strong>Aim: </strong>This research aims to study the demographics, indications, types of cholecystectomies (early/interval), length of hospital stays, conversion to open surgery, use of drains, complications, and outcomes.</p><p><strong>Patients and methods: </strong>This was a retrospective, descriptive study of all cases of laparoscopic cholecystectomy carried out from 1st January 2023 to 31st December 2023 at King Khalid hospital Hail, Saudi Arabia. The case files of all the patients who had laparoscopic cholecystectomy were retrieved from the Oasis health information management system of the hospital. Written informed consent was obtained from each patient before surgery. Ethical approval was obtained before embarking on the study. Information regarding demographics, indications and types of cholecystectomies, length of hospital stays, conversions to open surgery, use of drains, complications and mortality were analyzed with Statistical Package for Social Sciences version 26.</p><p><strong>Results: </strong>A total of 351 cases of cholecystitis had laparoscopic cholecystectomy. There were 248 (70.7%) females and 103 (29.3%) males. The mean age of the patients was 39.5 ± 1.2 years. There was conversion to open cholecystectomy in four (1.1%) cases. The average duration of hospital stay was 1.5 ± 1.5 days. There was neither a case of bile duct injury nor mortality.</p><p><strong>Conclusion: </strong>The outcome of laparoscopic cholecystectomy was good with no major morbidity or mortality.</p>","PeriodicalId":23680,"journal":{"name":"West African journal of medicine","volume":"42 5","pages":"379-386"},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145233522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical and Ultrasonographic Correlates of Knee Pain in Patients with Type 2 Diabetic Mellitus in a Nigerian Tertiary Hospital.","authors":"A S Aderibigbe, O O Ayoola, B A Kolawole, O Esan","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background and objectives: </strong>To ascertain the prevalence of knee pain in type 2 diabetic mellitus (T2DM) patients and to compare associated structural ultrasonographic arthritic changes with non-diabetic controls. Associations between T2DM knee pain, clinical variables and ultrasonographic arthritic changes were also investigated.</p><p><strong>Methods: </strong>Using a high frequency linear ultrasound probe (7.5-12MHz), both knees of 78 consecutive T2DM patients and 30 age and sex matched non-diabetic controls without knee pain were scanned.</p><p><strong>Results: </strong>Seventy-eight T2DM patients and 30 controls with mean ages of 63.0±10.4years (M:F = 1:1.9) and 2.3±10.5years (M:F = 1:0.9) respectively were studied. Forty (51.8%) T2DM patient presented with unilateral or bilateral knee pain while clinical pes anserinus tendinitis bursitis syndrome (PATBS) was diagnosed exclusively in 8 female T2DM patients, constituting 10.0% of the total T2DM group. At least 1 positive ultrasonographic arthritic change was found in 98.5% T2DM knees with pain, 86.8% T2DM knee without pain, and 69.2 % control knees (p< 0.05). Independent predictors of knee joint pain are age >60 years (OR=3.5), obesity (OR=2.9), and medial meniscal protrusion (OR=8.7).</p><p><strong>Conclusions: </strong>Ultrasonographic arthritic changes are highly prevalent in T2DM patients with and without knee pain. Independent predictors of knee joint pains are age > 60 years, obesity, and medial meniscal protrusion.</p>","PeriodicalId":23680,"journal":{"name":"West African journal of medicine","volume":"42 5","pages":"372-378"},"PeriodicalIF":0.0,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145233556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T N Maseko, J M Tsoka-Gwegweni, X Dlamini, Rejoice Nkambule, Velephi Okello
{"title":"Barriers and Facilitators to Utilization of Cervical Cancer Screening Services in Eswatini: A Scoping Review.","authors":"T N Maseko, J M Tsoka-Gwegweni, X Dlamini, Rejoice Nkambule, Velephi Okello","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>The implementation of cervical cancer screening programmes in Eswatini has been shown to be helpful in lowering both the occurrence and fatality rates associated with cervical cancer. However, there is a low level of screening participation among women.</p><p><strong>Aim: </strong>To provide a comprehensive synthesis of the barriers and facilitators to the uptake of cervical screening services from the perspectives of the healthcare providers (supply side) and the individuals receiving the screening (demand side) in Eswatini.</p><p><strong>Methods: </strong>The review followed the guidelines set out by the PRISMA scoping review criteria of peer-reviewed research publications that were published during the last five years. The publications included in the study were primarily centred on the documentation of Eswatini's nationwide endeavours in cervical cancer screening. A total of four databases were used, namely Medline, PubMed, CINAHL, and Google Scholar.</p><p><strong>Results: </strong>A total of 16 records fulfilled the established criteria for inclusion. The research primarily examined many aspects related to the supply side of cervical cancer (CC) screening. These aspects included the training and skills of health workers, the extent of CC screening service coverage, the capacity of health services, and the resource limitations that contribute to inadequate implementation and delivery of CC screening services.</p><p><strong>Conclusions: </strong>The outcomes of the review revealed the need for implementers to take into account the interplay between demand-side and supply-side elements that support the provision and acceptance of cervical cancer screening services.</p><p><strong>Contribution: </strong>The review presents evidence on barriers, enablers and practice in cervical cancer screening in Africa.</p>","PeriodicalId":23680,"journal":{"name":"West African journal of medicine","volume":"42 4","pages":"311-320"},"PeriodicalIF":0.0,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O S Ogah, O A Orimolade, A A Adebiyi, O M Adebayo, A Aje, A M Adeoye, A O Babatunde, M F Okeke, O P Attah, F O Obiekwe, C S Onuigbo, C M Ogah, T K Afolabi, E F Ayodele, M N Odenigbo, O O Oladapo
{"title":"Contemporary Baseline Clinical Profile of Chronic Hypertensive Heart Failure in Ibadan, Nigeria.","authors":"O S Ogah, O A Orimolade, A A Adebiyi, O M Adebayo, A Aje, A M Adeoye, A O Babatunde, M F Okeke, O P Attah, F O Obiekwe, C S Onuigbo, C M Ogah, T K Afolabi, E F Ayodele, M N Odenigbo, O O Oladapo","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Introduction: </strong>Cardiovascular disease (CVD) has become the major cause of morbidity and mortality in Sub-Saharan Africa (SSA). Despite this, there is still very little data on the pattern of hypertensive heart disease in SSA.</p><p><strong>Objective: </strong>This study described the characteristics of heart failure caused by hypertensive heart disease in Ibadan, Nigeria.</p><p><strong>Methods: </strong>This was a hospital-based cross-sectional study conducted in the cardiology unit of the Department of Medicine, University College Hospital, Ibadan, Nigeria. Eligible patients were those presenting with chronic hypertensive heart failure to the cardiology unit or referred to the unit for the same purpose. Data collection started from August 1, 2016, to July 31, 2021. Analysis was done with the SPSS statistical package. A 2-tailed p-value of <0.05 was assumed to be statistically significant.</p><p><strong>Results: </strong>A total of 753 subjects met the inclusion criteria for the study. The mean age of the population was 60.3 (range, 18-98 years). The most common co-morbidity was diabetes mellitus (13.9%). About 54% of the subjects had a previous history of heart failure. Serum sodium (p = 0.022), creatinine (p = 0.001), and total cholesterol (p = 0.004) were significantly higher in females. Men are more likely to have left-axis deviation (p=0.016) and left atrial abnormality (p=0.016). Heart failure with reduced ejection fraction was common in males.</p><p><strong>Conclusion: </strong>HHF in Ibadan, Nigeria, affects a relatively younger population compared to their counterparts in high-income countries. Our findings are similar to data from other parts of sub-Saharan Africa. Preventive programmes should be utilised at all levels to stem the menace of hypertension.</p>","PeriodicalId":23680,"journal":{"name":"West African journal of medicine","volume":"42 4","pages":"276-283"},"PeriodicalIF":0.0,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}