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The genome sequence of the false flower beetle, Anaspis frontalis (Linnaeus, 1758).
Wellcome Open Research Pub Date : 2025-02-19 eCollection Date: 2025-01-01 DOI: 10.12688/wellcomeopenres.23726.1
Maxwell V L Barclay, Svetlana Nikolaeva, Dmitry Telnov
{"title":"The genome sequence of the false flower beetle, <i>Anaspis frontalis</i> (Linnaeus, 1758).","authors":"Maxwell V L Barclay, Svetlana Nikolaeva, Dmitry Telnov","doi":"10.12688/wellcomeopenres.23726.1","DOIUrl":"https://doi.org/10.12688/wellcomeopenres.23726.1","url":null,"abstract":"<p><p>We present a genome assembly from a specimen of <i>Anaspis frontalis</i> (the false flower beetle; Arthropoda; Insecta; Coleoptera; Scraptiidae). The assembly contains two haplotypes with total lengths of 808.55 megabases and 802.05 megabases. Most of haplotype 1 (95.81%) is scaffolded into 8 chromosomal pseudomolecules, including the X chromosome, while haplotype 2 is a scaffold-level assembly. The mitochondrial genome has also been assembled and is 16.47 kilobases in length.</p>","PeriodicalId":23677,"journal":{"name":"Wellcome Open Research","volume":"10 ","pages":"82"},"PeriodicalIF":0.0,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11909497/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143650942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Embedding voices of under-served communities in Health Research Priority Setting in Thailand.
Wellcome Open Research Pub Date : 2025-02-18 eCollection Date: 2024-01-01 DOI: 10.12688/wellcomeopenres.22940.2
Napat Khirikoekkong, Supa-At Asarath, Anne Osterrieder, Khin Maung Lwin, Phaik Yeong Cheah
{"title":"Embedding voices of under-served communities in Health Research Priority Setting in Thailand.","authors":"Napat Khirikoekkong, Supa-At Asarath, Anne Osterrieder, Khin Maung Lwin, Phaik Yeong Cheah","doi":"10.12688/wellcomeopenres.22940.2","DOIUrl":"10.12688/wellcomeopenres.22940.2","url":null,"abstract":"<p><p>Health research is needed to develop new treatments, diagnostic methods and prevention strategies for many diseases, but resources are limited particularly in low-and middle-income countries (LMICs). Our proposed project involves in-depth engagement with community advisory boards and existing community groups in healthcare research priority setting in Thailand. We will use Wellcome's \"Responsive Dialogues\" engagement approach, focusing on \"under-served\" groups, as their voices are seldom heard in healthcare research priority setting. We estimate that we will engage with 6-8 community groups involving 48-80 participants. Our objectives are firstly, to contribute to the health research agenda setting in Thailand for government, non-governmental actors, academia, and others who conduct health research in the next 5 to 10 years. Secondly, we aim to identify ethical and practical issues related to healthcare research priority setting, specifically in relation to involving under-served communities.</p>","PeriodicalId":23677,"journal":{"name":"Wellcome Open Research","volume":"9 ","pages":"627"},"PeriodicalIF":0.0,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11883205/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Enhanced patient counselling and SMS reminder messages to improve access to community-based eye care services in Meru, Kenya: statistical analysis plan for a Bayesian adaptive trial.
Wellcome Open Research Pub Date : 2025-02-13 eCollection Date: 2025-01-01 DOI: 10.12688/wellcomeopenres.23495.1
Min Jung Kim, Luke Allen, Malebogo Tlhajoane, David Prieto-Merino, Nigel Bolster, Andrew Bastawrous, David Macleod
{"title":"Enhanced patient counselling and SMS reminder messages to improve access to community-based eye care services in Meru, Kenya: statistical analysis plan for a Bayesian adaptive trial.","authors":"Min Jung Kim, Luke Allen, Malebogo Tlhajoane, David Prieto-Merino, Nigel Bolster, Andrew Bastawrous, David Macleod","doi":"10.12688/wellcomeopenres.23495.1","DOIUrl":"10.12688/wellcomeopenres.23495.1","url":null,"abstract":"<p><strong>Background: </strong>Health service programmes frequently encounter challenges with patient adherence to care. A promising, low-risk approach to address this issue is providing patients with targeted information about the importance of adherence. In the Vision Impact Project (VIP), an eye health screening programme in Kenya, the adherence rate to attending triage clinics after referral is around 50%. To improve this rate, this trial will test the effectiveness of delivering relevant information to patients at the point of referral along with reminder messages.</p><p><strong>Methods: </strong>A pragmatic, Bayesian adaptive trial will be conducted within the VIP programme to assess the effectiveness of providing enhanced information compared to standard care. Weekly interim analyses will monitor adherence rates to referral appointments following positive vision impairment screenings. Participants will be randomized equally into intervention and control groups. The trial will stop if interim findings indicate either efficacy of one arm over the other, or futility that the two arms are performing equally.</p><p><strong>Discussion: </strong>This paper presents the statistical analysis plan for a pragmatic adaptive trial aimed at improving adherence in an eye screening programme in Kenya. This statistical analysis plan expands on the design and analysis plan detailed in the study protocol and documents decision rules to avoid post hoc decision-making.</p><p><strong>Trial registration: </strong>ISRCTN 11329596, Registered on 02 February 2024, https://doi.org/10.1186/ISRCTN11329596.</p>","PeriodicalId":23677,"journal":{"name":"Wellcome Open Research","volume":"10 ","pages":"69"},"PeriodicalIF":0.0,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11955077/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143754749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The genome sequence of the Twenty-plume Moth, Alucita hexadactyla Linnaeus, 1758.
Wellcome Open Research Pub Date : 2025-02-13 eCollection Date: 2025-01-01 DOI: 10.12688/wellcomeopenres.23736.1
Liam M Crowley, Peter W H Holland, David C Lees, Caroline Eve Mitchell
{"title":"The genome sequence of the Twenty-plume Moth, <i>Alucita hexadactyla</i> Linnaeus, 1758.","authors":"Liam M Crowley, Peter W H Holland, David C Lees, Caroline Eve Mitchell","doi":"10.12688/wellcomeopenres.23736.1","DOIUrl":"10.12688/wellcomeopenres.23736.1","url":null,"abstract":"<p><p>We present a genome assembly from a specimen of <i>Alucita hexadactyla</i> (Twenty-plume Moth; Arthropoda; Insecta; Lepidoptera; Alucitidae). The genome sequence has a total length of 878.53 megabases. Most of the assembly (99.74%) is scaffolded into 30 chromosomal pseudomolecules, including the Z sex chromosome. The mitochondrial genome has also been assembled and is 15.32 kilobases in length.</p>","PeriodicalId":23677,"journal":{"name":"Wellcome Open Research","volume":"10 ","pages":"70"},"PeriodicalIF":0.0,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11880763/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The genome sequence of the Large Red Tailed Bumble Bee, Bombus lapidarius (Linnaeus, 1758). 大红尾熊蜂 Bombus lapidarius (Linnaeus, 1758) 的基因组序列。
Wellcome Open Research Pub Date : 2025-02-12 eCollection Date: 2025-01-01 DOI: 10.12688/wellcomeopenres.23624.1
Olga Sivell, Duncan Sivell, Matthew N Smith
{"title":"The genome sequence of the Large Red Tailed Bumble Bee, <i>Bombus lapidarius</i> (Linnaeus, 1758).","authors":"Olga Sivell, Duncan Sivell, Matthew N Smith","doi":"10.12688/wellcomeopenres.23624.1","DOIUrl":"10.12688/wellcomeopenres.23624.1","url":null,"abstract":"<p><p>We present a genome assembly from an individual female specimen of <i>Bombus lapidarius</i> (Large Red Tailed Bumble Bee; Arthropoda; Insecta; Hymenoptera; Apidae). The genome sequence has a total length of 368.50 megabases. Most of the assembly (81.04%) is scaffolded into 18 chromosomal pseudomolecules. The mitochondrial genome has also been assembled and is 28.11 kilobases in length.</p>","PeriodicalId":23677,"journal":{"name":"Wellcome Open Research","volume":"10 ","pages":"67"},"PeriodicalIF":0.0,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11971630/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The genome sequence of the Alder Moth, Acronicta alni (Linnaeus, 1767).
Wellcome Open Research Pub Date : 2025-02-12 eCollection Date: 2025-01-01 DOI: 10.12688/wellcomeopenres.23704.1
Douglas Boyes, Clare Boyes
{"title":"The genome sequence of the Alder Moth, <i>Acronicta alni</i> (Linnaeus, 1767).","authors":"Douglas Boyes, Clare Boyes","doi":"10.12688/wellcomeopenres.23704.1","DOIUrl":"10.12688/wellcomeopenres.23704.1","url":null,"abstract":"<p><p>We present a genome assembly from a male <i>Acronicta alni</i> (Alder Moth; Arthropoda; Insecta; Lepidoptera; Noctuidae). The assembly contains two haplotypes with total lengths of 470.37 megabases and 472.86 megabases. Most of haplotype 1 (98.95%) is scaffolded into 31 chromosomal pseudomolecules, including the Z chromosome. Haplotype 2 was assembled to scaffold level. The mitochondrial genome has also been assembled and is 15.38 kilobases in length.</p>","PeriodicalId":23677,"journal":{"name":"Wellcome Open Research","volume":"10 ","pages":"68"},"PeriodicalIF":0.0,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11885909/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The genome sequence of the muscid fly Eudasyphora cyanicolor (Zetterstedt, 1845).
Wellcome Open Research Pub Date : 2025-02-10 eCollection Date: 2025-01-01 DOI: 10.12688/wellcomeopenres.23675.1
Steven Falk, Liam M Crowley, Ruth Y Akinmusola
{"title":"The genome sequence of the muscid fly <i>Eudasyphora cyanicolor</i> (Zetterstedt, 1845).","authors":"Steven Falk, Liam M Crowley, Ruth Y Akinmusola","doi":"10.12688/wellcomeopenres.23675.1","DOIUrl":"10.12688/wellcomeopenres.23675.1","url":null,"abstract":"<p><p>We present a genome assembly from an individual female specimen of <i>Eudasyphora cyanicolor</i> (Arthropoda; Insecta; Diptera; Muscidae). The genome sequence has a total length of 1,450.40 megabases. Most of the assembly (99.68%) is scaffolded into 5 chromosomal pseudomolecules. The mitochondrial genome has also been assembled and is 19.34 kilobases in length.</p>","PeriodicalId":23677,"journal":{"name":"Wellcome Open Research","volume":"10 ","pages":"56"},"PeriodicalIF":0.0,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11868753/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The genome sequence of the Jersey Tiger moth, Euplagia quadripunctaria (Poda, 1761).
Wellcome Open Research Pub Date : 2025-02-10 eCollection Date: 2025-01-01 DOI: 10.12688/wellcomeopenres.23666.1
David C Lees, Peter W H Holland
{"title":"The genome sequence of the Jersey Tiger moth, <i>Euplagia quadripunctaria</i> (Poda, 1761).","authors":"David C Lees, Peter W H Holland","doi":"10.12688/wellcomeopenres.23666.1","DOIUrl":"10.12688/wellcomeopenres.23666.1","url":null,"abstract":"<p><p>We present a genome assembly from an individual male specimen of <i>Euplagia quadripunctaria</i> (Jersey Tiger; Arthropoda; Insecta; Lepidoptera; Erebidae). The genome sequence has a total length of 668.40 megabases. Most of the assembly (99.6%) is scaffolded into 31 chromosomal pseudomolecules, including the Z sex chromosome. The mitochondrial genome has also been assembled and is 15.48 kilobases in length.</p>","PeriodicalId":23677,"journal":{"name":"Wellcome Open Research","volume":"10 ","pages":"53"},"PeriodicalIF":0.0,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11871433/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The genome sequence of a pallopterid fly, Toxonevra muliebris (Harris, 1780).
Wellcome Open Research Pub Date : 2025-02-10 eCollection Date: 2025-01-01 DOI: 10.12688/wellcomeopenres.23670.1
Maxwell V L Barclay, Gavin R Broad, Olga Sivell
{"title":"The genome sequence of a pallopterid fly, <i>Toxonevra muliebris</i> (Harris, 1780).","authors":"Maxwell V L Barclay, Gavin R Broad, Olga Sivell","doi":"10.12688/wellcomeopenres.23670.1","DOIUrl":"10.12688/wellcomeopenres.23670.1","url":null,"abstract":"<p><p>We present a genome assembly from an individual male specimen of <i>Toxonevra muliebris</i> (pallopterid fly; Arthropoda; Insecta; Diptera; Pallopteridae). The genome sequence has a total length of 491.40 megabases. Most of the assembly (99.07%) is scaffolded into 6 chromosomal pseudomolecules, including the X and Y sex chromosomes. The mitochondrial genome has also been assembled and is 16.18 kilobases in length. Gene annotation of this assembly on Ensembl identified 21,433 protein-coding genes.</p>","PeriodicalId":23677,"journal":{"name":"Wellcome Open Research","volume":"10 ","pages":"55"},"PeriodicalIF":0.0,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11880760/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The genome sequence of a carabid beetle, Carabus problematicus Herbst, 1786.
Wellcome Open Research Pub Date : 2025-02-10 eCollection Date: 2025-01-01 DOI: 10.12688/wellcomeopenres.23689.1
Duncan Sivell, Olga Sivell, Ryan Mitchell
{"title":"The genome sequence of a carabid beetle, <i>Carabus problematicus</i> Herbst, 1786.","authors":"Duncan Sivell, Olga Sivell, Ryan Mitchell","doi":"10.12688/wellcomeopenres.23689.1","DOIUrl":"10.12688/wellcomeopenres.23689.1","url":null,"abstract":"<p><p>We present a genome assembly from an individual female specimen of <i>Carabus problematicus</i> (carabid beetle; Arthropoda; Insecta; Coleoptera; Carabidae). The genome sequence has a total length of 254.00 megabases. Most of the assembly (97.1%) is scaffolded into 14 chromosomal pseudomolecules, including the X sex chromosome. The mitochondrial genome has also been assembled and is 21.42 kilobases in length. Gene annotation of this assembly on Ensembl identified 12,311 protein-coding genes.</p>","PeriodicalId":23677,"journal":{"name":"Wellcome Open Research","volume":"10 ","pages":"59"},"PeriodicalIF":0.0,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11880759/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568194","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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