{"title":"Early results of transabdominal preperitoneal inguinal hernia repair (TAPP) using invasive and non-invasive methods of mesh fixation.","authors":"Artem V Trots, Oleksandr V Perekhrestenko","doi":"10.36740/WLek/197109","DOIUrl":"https://doi.org/10.36740/WLek/197109","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To evaluate the early postoperative results of surgical treatment of patients with inguinal hernias after laparoscopic transabdominal preperitoneal inguinal hernia repair (TAPP) using invasive and non-invasive methods of fixation of prosthetic material.</p><p><strong>Patients and methods: </strong>Materials and Methods: The study included 76 patients (average age 61,4±15,3 years; 69 [91 %] males, 7 [9 %] females) with primary uncomplicated unilateral inguinal hernias who underwent TAPP. Patients were divided into two groups: group 1 - 52 patients in whom the AbsorbaTack fixation device was used to secure the mesh; group 2 - 24 patients in whom the LiquiBand FIX8 cyanoacrylate adhesive was used. In both groups, in the early postoperative period, the severity of pain according to Visual Analogue Scale (VAS) and functional activity according to the standard Carolinas Comfort Scale (CCS) were assessed.</p><p><strong>Results: </strong>Results: The severity of pain syndrome, according to VAS score, in the cyanoacrylate glue group was lower starting from postoperative day 7 (1,4±0,7 vs. 1,8±0,6 in group 1, respectively; p=0,026). On postoperative day 30, the functional activity indicators were better in the cyanoacrylate glue group (mean CCS score was 13,3±4,2 vs. 23,3±7,4 points, respectively; p=0,001). There was no difference in the incidence of early postoperative complications among the groups.</p><p><strong>Conclusion: </strong>Conclusions: Fixation of the mesh with cyanoacrylate glue during laparoscopic transabdominal preperitoneal inguinal hernia repair is a safe and effective technique that helps to reduce the level of postoperative pain and provides better functional results in patients in the early postoperative period compared to traditional methods of mesh fixation.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"77 11","pages":"2265-2270"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142882834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Volodymyr V Shmanko, Svitlana R Pidruchna, Roman V Hnizdyukh, Alla E Mudra, Uliana M Zakharchuk, Iryna P Kuzmak, Tetiana Y Yaroshenko, Lylya M Palytsya, Iryna A Bandas, Volodymyr H Dzhyvak, Iryna M Nikitina, Iryna F Zavarynska
{"title":"Changes in lipid profile parameters depending on the a1166c polymorphism of the angiotensin II type I receptor gene as a predictor of arterial hypertension.","authors":"Volodymyr V Shmanko, Svitlana R Pidruchna, Roman V Hnizdyukh, Alla E Mudra, Uliana M Zakharchuk, Iryna P Kuzmak, Tetiana Y Yaroshenko, Lylya M Palytsya, Iryna A Bandas, Volodymyr H Dzhyvak, Iryna M Nikitina, Iryna F Zavarynska","doi":"10.36740/WLek202408104","DOIUrl":"10.36740/WLek202408104","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To investigate lipid profile parameters depending the polymorphism of the A1166C I type gene receptor of the angiotensin II as a predictor of arterial hypertension.</p><p><strong>Patients and methods: </strong>Materials and Methods: The study involved 86 patients with arterial hypertension. The control group consisted of 30 practically healthy individuals. Indicators of lipid metabolism in the blood serum of patients were determined using \"Lachema\" kits on an analyzer. The the polymorphism of the A1166C I type gene receptor of the angiotensin II was studied by polymerase chain reaction with electrophoretic detection of the results.</p><p><strong>Results: </strong>Results: Higher levels of total cholesterol were found in patients with CC genotype compared to AA genotype carriers ((8.94±0.09) vs (5.18±0.02) mmol/L). The level of low-density lipoprotein in CC-genotype carriers was (7.43±0.03) versus (3.66±0.02) mmol/L in A-allele homozygotes. Triglycerides and very low density lipoproteins were also significantly higher in CC genotype carriers compared to patients with AA genotype. The level of high-density lipoprotein was lower in homozygotes with C-allele than in patients with the AA genotype, and was (0.59±0.12) versus (0.99±0.03) mmol/L.</p><p><strong>Conclusion: </strong>Conclusions: The presence in the CC genotype the I type gene receptor of the angiotensin II type is a predictor of dyslipidemia. In patients with arterial hypertension, the presence in the C-allele of the I type gene of the angiotensin II type contributes to a significant increase in serum adipokines and a decrease in ghrelin levels.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"77 8","pages":"1554-1561"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142133955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gulsym S Manasova, Yana A Stasy, Vyacheslav V Kaminsky, Igor Z Gladchuk, Ekaterina A Nitochko
{"title":"Histological and immunohistochemical features of the placenta associated with COVID-19: a systematic review and meta-analysis.","authors":"Gulsym S Manasova, Yana A Stasy, Vyacheslav V Kaminsky, Igor Z Gladchuk, Ekaterina A Nitochko","doi":"10.36740/WLek202407120","DOIUrl":"10.36740/WLek202407120","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To make a systematic review and meta-analysis of published data on the study of histological and immunohistochemical features of the placenta in women who had acute coronavirus infection associated with SARS-CoV-2 (\"Covid\" placentas) during pregnancy.</p><p><strong>Patients and methods: </strong>Materials and Methods: The search for literature data is based on the PRISMA methodology); the MEDLINE database (PubMed®) was searched using Medical Subject Headings terms from January 2020 to July 2023. The project was registered in the Open Sience Frame (Project Identifier: DOI 10.17605/OSF.IO/GDR3S, Registration DOI: https://doi.org/10.17605/OSF.IO/H2KPU). Preference was given to studies in which the description of placentas met the requirements of the Amsterdam Placental Workshop Group Consensus Statement.</p><p><strong>Results: </strong>Results: A total of 31 studies were included; the number of participants whose morphological and histological description of the placentas could be subjected to meta-analysis was 2401, respectively, in the group with a \"Covid\" history and 1910 - conditionally healthy pregnant women. Pathological changes in the placental complex were not detected in 42±19.62% of pregnant women with a history of Covid. Immunohistochemical examination of placentas preferably focuses on the detection of SARS-CoV-2 spike protein or ACE2. According to currently available studies, in the placentas of women who have had COVID-19 during pregnancy, there are no pathognomic histological patterns specific to this infection and direct damage to the placenta is rarely observed. Histological patterns in \"covid\" placentas are isolated, most often a combination of lesions in both the maternal and fetal malperfusion.</p><p><strong>Conclusion: </strong>Conclusions: According to currently available studies, in the placentas of women who have had COVID-19 during pregnancy, there are no pathognomic histological patterns specific to this infection and direct damage to the placenta is rarely observed. The probability of infection of the intrauterine fetus by the transplacental hematogenous route is the lowest compared to other routes, which, in our opinion, is a possible explanation for the high frequency of MVM without subsequent infection of the fetus.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"77 7","pages":"1434-1455"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142143393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oleksander Y Ioffe, Victor O Nevmerzhytskyi, Mykola S Kryvopustov, Yurii P Tsiura, Taras M Galyga, Stepan L Kindzer, Vladislav M Perepadya
{"title":"Improving the management of morbidly obese patients with postoperative bleeding undergoing Roux-en-Y gastric bypass.","authors":"Oleksander Y Ioffe, Victor O Nevmerzhytskyi, Mykola S Kryvopustov, Yurii P Tsiura, Taras M Galyga, Stepan L Kindzer, Vladislav M Perepadya","doi":"10.36740/WLek202406103","DOIUrl":"https://doi.org/10.36740/WLek202406103","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To improve the management of morbidly obese patients who undergo gastric bypass surgery to reduce the number of postoperative complications, in particular, bleeding.</p><p><strong>Patients and methods: </strong>Materials and Methods: From 2011 to 2022, a total of 348 patients with morbid obesity (MO) underwent laparoscopic gastric bypass treatment at the clinical base of the Department of General Surgery №2 of Bogomolets National Medical University. The retrospective group included 178 patients who received treatment between 2011 and 2019. 170 patients were enrolled in the prospective group for the period from 2019 to 2022.</p><p><strong>Results: </strong>Results: Retrospective group had 8 episodes of postoperative bleeding, representing a rate of 4.49%, prospective group - 3 episodes of postoperative bleeding, representing a rate of 1.76% Four factor characteristics associated with the probability of bleeding were identified: \"number of comorbid conditions\", \"arterial hypertension\", \"chronic liver diseases\" and \"chronic obstructive pulmonary disease\".</p><p><strong>Conclusion: </strong>Conclusions: The factors responsible for the occurrence of postoperative bleeding in morbidly obese patients after laparoscopic gastric bypass surgery were the number of comorbid conditions, the presence of arterial hypertension, the presence of chronic liver diseases, and chronic obstructive pulmonary disease. A new strategy for the management of morbidly obese patients after laparoscopic gastric bypass was developed. This strategy involves changing cassettes to create gastroentero- and enteroenteroanastomoses, reducing the period of use of the nasogastric tube, drains, and urinary catheter from 3-4 days to 1 day, and resuming the drinking regimen 6 hours after extubation.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"77 6","pages":"1127-1133"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141898407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The association of inflammatory changes of the uterus and chorioamniotic membranes with different types of labor activity anomalies.","authors":"Kateryna L Shatylovych, Leonid B Markin","doi":"10.36740/WLek202408108","DOIUrl":"https://doi.org/10.36740/WLek202408108","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To clarify the association between different types of uterine contractility dysfunction and the inflammation of the uterus and chorioamniotic membranes.</p><p><strong>Patients and methods: </strong>Materials and Methods: The association between the inflammation of the uterine layers, chorioamniotic membranes, umbilical cord, and different types of labor activity abnormalities was examined in 382 patients with singleton pregnancies at 28-42 weeks' gestation who underwent Caesarean section (CS) for abnormal uterine contractions and other complications. Statistical analyses included the Mann-Whitney U, Chi-squared test, and logistic regression.</p><p><strong>Results: </strong>Results: In the control group, slight infiltration with polymorphonuclear leukocytes (PMNs) and macrophages of the myometrium and decidua of the lower uterine segment at term pregnancy was found in 59.7% and 73.6% of cases. The main clinical risk factors for placental and decidual membrane inflammation in patients with excessive uterine activity (EUA) were prematurity, multiparity, group B streptococcus (GBS) colonization, and duration of ruptured fetal membranes before the CS. Moderate or marked myometrial inflammation of both uterine segments in the EUA group was diagnosed only in patients with cervical dilation of >6 cm and duration of labor of >8h. In women with hypotonic uterine activity (HUA), decidual and myometrial inflammation was significantly associated with nulliparity and intrapartum factors, such as protracted active first stage of labor, advanced cervical dilation, and number of vaginal examinations. In all cases, inflammation of the myometrium was accompanied by deciduitis.</p><p><strong>Conclusion: </strong>Conclusions: Mild inflammation of the decidual membrane and myometrium of the lower segment at term pregnancy is a common physiological phenomenon contributing to labor initiation. Uterine hyperfunction comes as the response of the unaffected myometrium to the release of high concentrations of proinflammatory cytokines produced by the inflamed decidual and chorioamniotic membranes into the bloodstream. Marked myometrial inflammation that occurs in prolonged labor is an additional factor aggravating the hypotonic uterine activity.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"77 8","pages":"1582-1592"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142133916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ivan R Romash, Iryna B Romash, Mykhaylo M Pustovoyt
{"title":"Study of the influence of disease duration on glutatione-dependent ensymes dynamics in patients with paranoid schizophrenia.","authors":"Ivan R Romash, Iryna B Romash, Mykhaylo M Pustovoyt","doi":"10.36740/WLek202407102","DOIUrl":"https://doi.org/10.36740/WLek202407102","url":null,"abstract":"<p><strong>Objective: </strong>Aim: The objective of the research was to conduct a comprehensive longitudinal analysis of the temporal dynamics of glutathione system functionality in individuals diagnosed with paranoid schizophrenia. Specifically, the research was focused on investigating variations in the profiles of glutathione-dependent enzymes, with meticulous consideration given to the duration of the illness.</p><p><strong>Patients and methods: </strong>Materials and Methods: The study group comprised 300 individuals officially diagnosed with 'Paranoid Schizophrenia,' subdivided into five subgroups, each consisting of 60 patients. The subgroups were defined as follows: Subgroup I included 60 patients with a disease duration ranging from 3 to 5 years; Subgroup II comprised 60 patients with a duration of 6 to 10 years; Subgroup III consisted of 60 patients with a duration of 11 to 15 years; Subgroup IV included 60 patients with a duration of 16 to 20 years; and Subgroup V encompassed 60 patients with a duration of 21 years and older. The comparison group comprised 20 patients diagnosed with \"Primary psychotic episode\".</p><p><strong>Results: </strong>Results: The research demonstrates a consistent and noteworthy reduction in the enzymatic activities of glutathione peroxidase, glutathione reductase, and glutathione-S-transferase in various Subgroups of paranoid schizophrenia patients. The observed declines are particularly prominent within the first 3-5 years of the illness, show casing statistically significant reductions. Patients with prolonged illness durations, especially surpassing 21 years, display substantial reductions in all three enzymes, suggesting a cumulative enzymatic impact associated with prolonged illness.</p><p><strong>Conclusion: </strong>Conclusions: The identification of critical periods of inhibition in the glutathione protection chain, provides valuable information about potential therapeutic interventions for individuals with paranoid schizophrenia.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"77 7","pages":"1311-1317"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142143403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The efficacy and safety of vitamin D supplementation in women with polycystic ovarian syndrome undergoing ovulation induction using letrozole.","authors":"Asma A Swadi, Hussein A Saheb, Ahmed M Sultan","doi":"10.36740/WLek202409116","DOIUrl":"https://doi.org/10.36740/WLek202409116","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To examine the role of vitamin D supplementation in PCOS women who failed to ovulation induction by letrozole in previous trials.</p><p><strong>Patients and methods: </strong>Materials and Methods: The study included 30 women diagnosed with PCOS and were complaining from primary infertility. Those women had previously been treated for 3 months with letrozole to induce ovulation, but there was failure of response to treatment. Those 30 women were selected from a pool of women who were evaluated for serum vitamin D and were proved to have vitamin D def i ciency (<20 ng/ml).</p><p><strong>Results: </strong>Results: Daily monitoring of ovulation by transvaginal ultrasound was done staring from day 7 till day 25 of the cycle. The main outcomes were the number and the size of follicles. In addition, they were followed up for evidence of pregnancy using biochemical serum and urine examination.</p><p><strong>Conclusion: </strong>Conclusions: When women with polycystic ovarian syndrome are treated with letrozole, vitamin D supplementation enhances both the result of ovulation induction and pregnancy.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"77 9","pages":"1753-1758"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142645029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Inna M Isaieva, Arsen M Isaiev, Nataliia V Korobtsova, Viktoriia V Nadon, Iryna I Puchkovska
{"title":"Aggressive parenting: social, medical and legal aspects.","authors":"Inna M Isaieva, Arsen M Isaiev, Nataliia V Korobtsova, Viktoriia V Nadon, Iryna I Puchkovska","doi":"10.36740/WLek202401118","DOIUrl":"10.36740/WLek202401118","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To examine the impacts of aggressive parenting on physical, mental and emotional development; outcomes for society; possible ways of prevention of children' rights or health violation and responsibility of parents to optimize well-being of children.</p><p><strong>Patients and methods: </strong>Materials and Methods: The analysis of scientific data has been conducted on the basis of PubMed, Scopus and Web of Science databases in order to collect the existed results of researches about social and medical aspects of impact of aggressive parenting. The formal-legal method was used to interpret the provisions of legislation regarding the protection of personal non-property rights and responsibilities of parents and children.</p><p><strong>Conclusion: </strong>Conclusions: Aggressive parenting affects children of all ages and is associated with chronic stress and long-term negative impacts on physical development, cognitive and behavioral dysfunction, socioemotional difficulties, social and psychological dysfunction in adulthood. Aggressive parenting triggers a child' aggressive behavior which is considered as a predictor of adult's criminality. From a legal standpoint, aggressive parenting is a form of violation of the responsibility of parents to educate a child, which is an element of family legal relations regulated by the norms of the family law institution known as ≪Personal non-property rights and responsibilities of parents and children\". The definition of aggressive parenting has been defined with its legal features and characteristics. Effective prevention methods should be directed to predict possible further parental violence, intervention programs to reduce outcomes of aggressive parenting and to improve the ways of responsibility in procedural and material aspects of law.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"77 1","pages":"144-152"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140022681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The associations of cytokines and gens polymorphisms of β-adrenoceptors in patients with heart failure and some thyroid pathology (literature review and own observations).","authors":"Sergiy M Pyvovar, Iurii Rudyk, Tetiana D Scherban","doi":"10.36740/WLek202401113","DOIUrl":"10.36740/WLek202401113","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To analyze the role of cytokines in the progression of heart failure (HF) in patients with concomitant pathology of the thyroid gland.</p><p><strong>Patients and methods: </strong>Materials and Methods: The systematization of literature data on the role of cytokines in the progression of HF in patients with concomitant thyroid pathology (TP) was carried out. The results of our own research were presented.</p><p><strong>Conclusion: </strong>Conclusions: The final chapter in the history of the role of cytokines in the progression of HF has not yet been written. Further studies, including genetic ones, are necessary. The patients with HF have higher levels of TNFβ and IL-6, and a lower concentration of IL-4, compared to the control group. Patients with a fatal outcome of the disease, in contrast to those who survived for two years, have an increased level of TNFβ. In patients with concomitant TP, who had repeated hospitalization, a lower level was registered, compared to that under conditions of a more favorable course of heart failure. Concentrations of cytokines in the blood of patients with HF are associated with gene polymorphisms of the β-adrenoreceptor system: the C-allele of the Gly389A polymorphism of the β1-adrenoceptor gene leads to a decrease in the risk of increasing TNFα; IL-1α increases in the presence of the A-allele of the Ser49Gly polymorphism of this gene. In patients with HF and concomitant thyroid pathology, the risk of IL-6 growth increases in homozygous (C) patients for the Ser275 polymorphism of the β3 subunit of the G-protein.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"77 1","pages":"105-113"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140022757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessment of the potential effects of l-carnitine and cinnamon supplementation on weight loss and body composition.","authors":"Qayssar Joudah Fadheel","doi":"10.36740/WLek202403115","DOIUrl":"https://doi.org/10.36740/WLek202403115","url":null,"abstract":"<p><strong>Objective: </strong>Aim: To assess efficacy of L-carnitine and cinnamon alone and in combination on body composition parameters in addition to compare between them.</p><p><strong>Patients and methods: </strong>Materials and Methods: Sample of 28 obese and overweight adults in Babylon city, sample collection includes patients in places, or by internet, where interview take place according to specialize questionnaire height, weight, and body mass index were measured.</p><p><strong>Results: </strong>Results: A significant differences P<0.05 among gender distribution between male and female. A significant difference between (150-160 cm, 160-170 cm) as compared with (170-180 cm, 180-190 cm). A significant difference between 170-180 cm as compared with 180-190 cm but non-significant differences between 150-160 cm as compared with 160-170 cm. A significant difference between 26-35 as compared with 36-45, 46-55, but non-significant differences between 36-45 as compared with 46-55. A significant difference between body weight, body fat, water content, skeletal muscle, and body mass index after treatment, but non-significant differences between protein, and inorganic salt after treatment and at baseline. A significant difference between body weight, water content, skeletal muscle, and body mass index in group treated with cinnamon as compared with negative control group, but non-significant differences between body fat, protein, and inorganic salt as compared with negative control group.</p><p><strong>Conclusion: </strong>Conclusions: The prevalence of overweight and obesity within accepted range of that reported in Iraq, important relationship was reported between several life style risk factor, as soon as diagnose increase in weight and education health program for behavior of life style were high recommended.</p>","PeriodicalId":23643,"journal":{"name":"Wiadomosci lekarskie","volume":"77 3","pages":"472-483"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140858122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}