Vascular Medicine最新文献_第7页

How to start a vascular diagnostic laboratory - Tips and tricks of the trade. 如何开始一个血管诊断实验室-提示和技巧的贸易。

IF 3 3区医学

Vascular Medicine Pub Date : 2025-04-01 Epub Date: 2025-04-23 DOI: 10.1177/1358863X251326066

Jun-Yang Lou, G Jay Bishop

引用次数: 0

Variation in compressive mechanical properties between subacute and chronic venous thrombosis in a novel unilateral iliac thrombosis model. 在一个新的单侧髂血栓模型中，亚急性和慢性静脉血栓形成的压缩力学特性的变化。

IF 3 3区医学

Vascular Medicine Pub Date : 2025-04-01 Epub Date: 2025-01-21 DOI: 10.1177/1358863X241308481

Nathaniel J Parchment, Christian Argenti, Sriganesh B Sharma, Oscar Moreno, David Gordon, Laura Durham, Veronica Forsythe, David M Williams, Thomas W Wakefield, Nathan Weidenhamer, Daniel Durant Myers, Minhaj S Khaja, Peter K Henke, Albert J Shih, Andrea Tara Obi

{"title":"Variation in compressive mechanical properties between subacute and chronic venous thrombosis in a novel unilateral iliac thrombosis model.","authors":"Nathaniel J Parchment, Christian Argenti, Sriganesh B Sharma, Oscar Moreno, David Gordon, Laura Durham, Veronica Forsythe, David M Williams, Thomas W Wakefield, Nathan Weidenhamer, Daniel Durant Myers, Minhaj S Khaja, Peter K Henke, Albert J Shih, Andrea Tara Obi","doi":"10.1177/1358863X241308481","DOIUrl":"10.1177/1358863X241308481","url":null,"abstract":"Background: Interventional therapies to relieve chronic deep vein thrombosis (DVT) fail through inability to penetrate, cross, and remove the occlusion. Development of suitable tools requires fundamental understanding of chronic DVT mechanical properties and a reliable model for testing. Methods: Female farm swine underwent a novel, endovenous generation of long-segment unilateral iliac vein thrombosis. Thrombus was confirmed via venogram, intravascular ultrasound, and transabdominal duplex for 14 days. Thrombus components were quantified via histology. Thrombus mechanical properties were assessed via uniaxial compression. Results: Among seven swine, technical success was 100%. Compared to subacute thrombi (7-day), chronic thrombi (14-day) showed organizing thrombus with diffuse myointimal thickening and collagen matrix formation on histology. The thrombi collagen content was 41% versus 55% (p = 0.17) and the thrombus erythrocyte percentage was 4.3% versus 2.2%, p = 0.21 in 7- versus 14-day thrombi, respectively. The onset point (compression required to load the thrombus fiber network) was 66.6% versus 35.3% (p = 0.004), the secant modulus (resistance to deformation) measured at the onset point was 153.8 versus 275.99 kPa (p = 0.18), and the average shear constant (resistance to shearing), as defined by the Yeoh hyperelastic model, was 1.85 kPa versus 2.85 kPa in 7- versus 14-day thrombi. Conclusions: This study demonstrates the feasibility of an endovenous model generating chronic unilateral venous thrombi in 2 weeks with similar anatomy to humans and provides critical mechanical properties of thrombi for future research.","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"124-135"},"PeriodicalIF":3.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143011334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Is lipedema a progressive disease? 脂水肿是一种进行性疾病吗？

IF 3 3区医学

Vascular Medicine Pub Date : 2025-04-01 Epub Date: 2025-01-20 DOI: 10.1177/1358863X241306415

Isabel Forner-Cordero, José Muñoz-Langa

{"title":"Is lipedema a progressive disease?","authors":"Isabel Forner-Cordero, José Muñoz-Langa","doi":"10.1177/1358863X241306415","DOIUrl":"10.1177/1358863X241306415","url":null,"abstract":"Background: It is not yet known whether lipedema is a progressive chronic disease or not. The aim of this paper is to describe the long-term changes in the volume of the lower limbs.Methods: The primary endpoint of this prospective cohort study of patients with lipedema was the percentage of volume change (PVC) during follow up. Progression was defined as when the PVC was > 10% from the baseline, whereas improvement was defined as when the PVC was < -10%, and stability as PVC -10% to 10%.Results: A cohort of 100 patients with lipedema were included in the study. The average follow-up period from the start of this study was 4.6 years. The average PVC was 2.8%. Stability was observed in 62% of the patients, progression in 28%, and improvement in 10%. In the univariate analysis, a significant positive association was observed between PVC and both BMI-change and waist-to-height ratio (WHtR)-change. The more the BMI increased, the more the lipedema progressed (p < 0.0001), as did the WHtR (p < 0.0001). In the adjusted regression analysis, age was not seen to be an influencing factor for PVC. Regarding maintenance therapies, no associations were observed.Conclusion: Lipedema was seen to be stable in two-thirds of the patients. Age was not related to progression. Progression was related to WHtR increase, which is an indicator of abdominal fat gain. This demonstrates the relationship between fat gain and lipedema progression.","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"205-212"},"PeriodicalIF":3.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recurrence patterns and clinical outcomes following paclitaxel-coated balloon angioplasty in femoropopliteal artery disease: Results of the CRESCENT study. 股腘动脉疾病紫杉醇包被球囊血管成形术后的复发模式和临床结果：CRESCENT研究的结果

IF 3 3区医学

Vascular Medicine Pub Date : 2025-03-24 DOI: 10.1177/1358863X251322731

Naoki Yoshioka, Takahiro Tokuda, Akiko Tanaka, Shunsuke Kojima, Kohei Yamaguchi, Takashi Yanagiuchi, Kenji Ogata, Tatsuro Takei, Yasuhiro Morita, Tatsuya Nakama, Itsuro Morishima

{"title":"Recurrence patterns and clinical outcomes following paclitaxel-coated balloon angioplasty in femoropopliteal artery disease: Results of the CRESCENT study.","authors":"Naoki Yoshioka, Takahiro Tokuda, Akiko Tanaka, Shunsuke Kojima, Kohei Yamaguchi, Takashi Yanagiuchi, Kenji Ogata, Tatsuro Takei, Yasuhiro Morita, Tatsuya Nakama, Itsuro Morishima","doi":"10.1177/1358863X251322731","DOIUrl":"https://doi.org/10.1177/1358863X251322731","url":null,"abstract":"Background: Paclitaxel-coated balloons (PCBs) are widely used for femoropopliteal artery (FPA) diseases. However, data on recurrence and recurrence patterns after PCB angioplasty are limited. This study investigated the association between recurrence patterns, baseline characteristics, and clinical outcomes in the cases following PCB angioplasty.Methods: This multicenter, retrospective study included 1159 limbs in 1031 patients treated for de novo FPA lesions using PCBs. Patients were classified into three groups (patency, restenosis, and reocclusion) according to patency or recurrence patterns within 2 years after the index PCB angioplasty. The primary outcome was the incidence of target lesion revascularization (TLR), and the secondary outcome was the pattern of re-recurrence within 2 years following TLR using PCBs.Results: When comparing the three groups, reocclusive cases were characterized by more complex lesions, including chronic total occlusion, at baseline. Following the index PCB angioplasty, approximately 70% of recurrent cases underwent TLR, which was performed more frequently in reocclusive than in restenotic cases (82.1% vs 63.7%). Conversely, a higher percentage of restenotic cases did not require TLR compared to reocclusive cases (10.3% vs 27.8%). In cases where TLR was performed using PCBs, the rate of re-recurrence with occlusive morphology was significantly higher in reocclusive than in restenotic cases (52.3% vs 24.3%).Conclusions: After PCB angioplasty for FPA lesions, symptomatic recurrence and requirement for TLR were more frequent in reocclusive cases. Even after TLR using PCBs, reocclusive cases tend to recur with occlusion.","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"1358863X251322731"},"PeriodicalIF":3.0,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143693582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pathological and clinical findings of calcified nodules in carotid artery stenosis: A study of 508 consecutive carotid endarterectomies. 颈动脉狭窄中钙化结节的病理和临床表现：对508例连续颈动脉内膜切除术的研究。

IF 3 3区医学

Vascular Medicine Pub Date : 2025-03-13 DOI: 10.1177/1358863X251324159

Kiyofumi Yamada, Kinta Hatakeyama, Kisaki Amemiya, Masanori Kawasaki, Soichiro Abe, Hirotoshi Imamura, Hisae Mori, Manabu Shirakawa, Shinichi Yoshimura, Koji Iihara, Hiroharu Kataoka

引用次数: 0

Relationship between calf muscle pump function and severity of chronic venous disease. 小腿肌泵功能与慢性静脉疾病严重程度的关系。

IF 3 3区医学

Vascular Medicine Pub Date : 2025-02-10 DOI: 10.1177/1358863X241311254

Atefeh Ghorbanzadeh, David Liedl, Hossam Elbenawi, Thom Rooke, Paul Wennberg, Robert D McBane, Damon E Houghton

{"title":"Relationship between calf muscle pump function and severity of chronic venous disease.","authors":"Atefeh Ghorbanzadeh, David Liedl, Hossam Elbenawi, Thom Rooke, Paul Wennberg, Robert D McBane, Damon E Houghton","doi":"10.1177/1358863X241311254","DOIUrl":"https://doi.org/10.1177/1358863X241311254","url":null,"abstract":"Background: The calf muscle pump is an understudied contributor to venous return from the lower extremity. This study aimed to determine if calf pump function (CPF) is independently associated with the severity of chronic venous disease classified by CEAP (Clinical-Etiology-Anatomy-Pathophysiology).Methods: The Mayo Clinic Vascular Laboratory database was analyzed from January 2015 through September 2023. Ambulatory adults who underwent venous air plethysmography were included. Venous plethysmography assessed the severity of venous incompetence, and CPF was measured as ejection fraction (EF) per leg. The clinical component (C0 through C6) of the CEAP score was evaluated for each extremity at the time of the study.Results: A total of 7760 limbs from 3733 patients were analyzed. The mean age was 62 years, with 62% women. Venous obstruction was detected in 3.2% of limbs. Venous incompetence severity was categorized as normal (44%), mild (26%), moderate (19%), and severe (10%). A significant trend of reduced CPF was observed with higher CEAP scores (p < 0.001). Multivariable logistic regression, adjusted for age, sex, degree of venous incompetence, and obstruction showed reduced CPF was a significant predictor (odds ratio 1.84, CI: 1.5-2.2) of active/prior ulcer (C5 or C6). In contrast to more severely reduced CPF, mildly reduced CPF (EF 40-49%) was not associated with active/prior ulcers.Conclusion: This large contemporary study demonstrates that decreased CPF is associated with worse chronic venous disease. Importantly, we demonstrate for the first time that CPF is independently associated with active/prior venous ulcers after accounting for other venous physiologic parameters and demographics.","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"1358863X241311254"},"PeriodicalIF":3.0,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143383324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Platelet pals: How blood cells shape the future of the aorta. 血小板伙伴：血细胞如何塑造主动脉的未来。

IF 3 3区医学

Vascular Medicine Pub Date : 2025-02-01 Epub Date: 2025-01-01 DOI: 10.1177/1358863X241309832

Anu Aggarwal, A Phillip Owens, Scott J Cameron

引用次数: 0

Vascular Disease Patient Information Page: Renal artery stenosis. 血管疾病患者信息页面：肾动脉狭窄。

IF 3 3区医学

Vascular Medicine Pub Date : 2025-02-01 Epub Date: 2025-01-06 DOI: 10.1177/1358863X241307910

Natalie Rilo, Shivani Lam, Bryan J Wells

引用次数: 0

Altered platelet phenotype in patients with type II endoleaks following abdominal aortic aneurysm repair. 腹主动脉瘤修复后II型内漏患者血小板表型的改变。

IF 3 3区医学

Vascular Medicine Pub Date : 2025-02-01 Epub Date: 2024-12-03 DOI: 10.1177/1358863X241298926

Muhammad Yogi Pratama, Benjamin King, Katherine A Teter, Christina Bi, Natalie Presedo, Keerthi B Harish, Catarina Santos Giardinetto, Sheehan Belleca, Ethan Chervonski, Thomas S Maldonado, Bhama Ramkhelawon

{"title":"Altered platelet phenotype in patients with type II endoleaks following abdominal aortic aneurysm repair.","authors":"Muhammad Yogi Pratama, Benjamin King, Katherine A Teter, Christina Bi, Natalie Presedo, Keerthi B Harish, Catarina Santos Giardinetto, Sheehan Belleca, Ethan Chervonski, Thomas S Maldonado, Bhama Ramkhelawon","doi":"10.1177/1358863X241298926","DOIUrl":"10.1177/1358863X241298926","url":null,"abstract":"Background: Endovascular abdominal aortic aneurysm repair (EVAR) is a preferred surgery to prevent aneurysm sac enlargement and minimize the risk of life-threatening rupture in patients with AAA. Serious complications of type II endoleaks following EVAR can cause sac expansion and increase rupture risk. This study focused on evaluating clinical and blood characteristics in patients with type II endoleaks to refine our understanding of systemic fluctuations associated with unsuccessful EVAR.Methods: This retrospective study included 146 patients with AAA who underwent primary elective endovascular procedures (EVAR/fEVAR) between 2013 and 2021. Clinical characteristics, complete blood count (CBC) and imaging data were analyzed from patients who did and did not develop type II endoleaks.Results: Mean platelet volume (MPV) was significantly increased in patients who developed type II endoleaks after EVAR. Receiver operating characteristic analysis showed that MPV has a satisfactory discriminatory performance in distinguishing post-EVAR patients who developed type II endoleaks, yielding an area under the curve (AUC) value of 0.64. A risk stratification panel incorporating MPV, type II diabetes history, and administration of dual antiplatelet therapies yielded an AUC of 0.70 and predicted an endoleak-free survival rate with a hazard ratio of 2.94. A nomogram revealed that MPV had the highest scoring weight among all significant variables.Conclusion: Patients with type II endoleaks following EVAR have elevated MPV indicative of different phenotypes of circulating platelets. MPV presents an attractive predictive criteria for assessing the occurrence of type II endoleaks in patients with AAA.","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"38-47"},"PeriodicalIF":3.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142772776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Images in Vascular Medicine: Internal carotid artery anatomic variation alters treatment for high-grade stenosis. 血管医学影像：颈内动脉解剖变异改变了高度狭窄的治疗。

IF 3 3区医学

Vascular Medicine Pub Date : 2025-02-01 Epub Date: 2024-12-10 DOI: 10.1177/1358863X241300250

Michalis Pesmatzoglou, Nikolaos Kontopodis, Christos V Ioannou

引用次数: 0