Vascular MedicinePub Date : 2025-06-01Epub Date: 2025-03-13DOI: 10.1177/1358863X251318652
Margaret A Reilly, Megan E Alagna, Cassandra Iroz, Emily Ho, Alexander Lundberg, Andrew W Hoel, Ashley K Vavra, Julie K Johnson, Karen J Ho
{"title":"Patient factors associated with activation level in peripheral artery disease.","authors":"Margaret A Reilly, Megan E Alagna, Cassandra Iroz, Emily Ho, Alexander Lundberg, Andrew W Hoel, Ashley K Vavra, Julie K Johnson, Karen J Ho","doi":"10.1177/1358863X251318652","DOIUrl":"10.1177/1358863X251318652","url":null,"abstract":"<p><strong>Introduction: </strong>As a chronic and incurable condition, lower extremity peripheral artery disease (PAD) and its optimal self-management requires patient participation in treatment. Patient activation (knowledge, skills, and confidence to manage one's health) is known to improve chronic disease outcomes. We aimed to identify factors associated with activation in patients with PAD.</p><p><strong>Methods: </strong>In this single-center study, participants with PAD completed a survey assessing demographics, activation, PAD knowledge, and functional health literacy (FHL). The primary outcome, activation, was measured by the Patient Activation Measure (PAM-13). The PAD knowledge score was the percentage of correct responses, and FHL was assessed using the Short Test of Functional Health Literacy in Adults (S-TOFHLA). Bivariable analysis and logistic regression identified factors associated with activation.</p><p><strong>Results: </strong>Of the 91 participants (49.5% women, mean ± SD age: 68.6 ± 11.9 years, 29.7% Black), 72.6% were activated, 78.7% demonstrated adequate FHL, and the mean knowledge score ± SD was 79.1% ± 13.3%. White race (<i>p</i> = 0.025), higher income (<i>p</i> = 0.015), ability to ambulate (<i>p</i> = 0.023), and increased knowledge score (<i>p</i> = 0.002) were associated with activation in bivariable analyses. In a logistic regression model, younger age (<i>p</i> = 0.029), higher income (<i>p</i> = 0.016), and higher knowledge score (<i>p</i> = 0.012) independently correlated with odds of greater activation.</p><p><strong>Conclusions: </strong>Many participants were activated, demonstrated adequate FHL, and scored well on the PAD knowledge test. The remaining 27.5% were inactivated, which was associated with poor PAD knowledge and certain demographic characteristics. Future studies should focus on developing and implementing patient-centric educational interventions for inactivated patients and strategies to increase activation.</p>","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"283-292"},"PeriodicalIF":3.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143625710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vascular MedicinePub Date : 2025-05-21DOI: 10.1177/1358863X251336736
Beth L Cheshire, Sarah J Messeder, Coral J Pepper, Lucy C Beishon, Rob D Sayers, John Sm Houghton
{"title":"Association of cognitive impairment and peripheral artery disease (PAD): A systematic review.","authors":"Beth L Cheshire, Sarah J Messeder, Coral J Pepper, Lucy C Beishon, Rob D Sayers, John Sm Houghton","doi":"10.1177/1358863X251336736","DOIUrl":"https://doi.org/10.1177/1358863X251336736","url":null,"abstract":"<p><p>This systematic review aimed to describe the association between peripheral artery disease (PAD) and cognitive impairment or dementia. We included studies reporting on the association between PAD (defined by ankle-brachial index ⩽ 0.9) and cognitive function in adult populations. MEDLINE, Embase, CINAHL, PsycINFO, and CENTRAL were systematically searched from inception to January 2025. Study quality was assessed using the Risk of Bias In Nonrandomized Studies of Exposure effects (ROBINS-E) tool. A narrative synthesis was undertaken structured by cognitive outcome and study design. Thirty-eight studies were included in the review (58,586 participants). The results provide evidence that PAD is associated with cognitive impairment. Seventeen (81%) cross-sectional studies and four (67%) longitudinal studies reported associations of PAD with poorer cognitive performance or increased risk of cognitive impairment. Impaired memory and processing speed were most frequently associated with PAD. PAD was also associated with increased dementia risk in cross-sectional (odds ratios = 1.50-2.41) and longitudinal studies (hazard ratios = 1.03-2.40), although proportionally fewer longitudinal studies reported significant association of PAD with dementia. Results suggest increased prevalence of cognitive impairment, independent of cardiovascular risk factors and cerebrovascular disease. Awareness of the prevalence of cognitive impairment and its potential impact on treatment adherence and engagement in a healthy lifestyle is important for clinicians treating patients with PAD. Screening for cognitive impairment in those with PAD may aid early diagnosis and management of cognitive impairment in this high-risk population. Further research is required to determine whether screening for and optimal management of PAD has cognitive benefits. <b>(PROSPERO Registration No.: CRD42023399608)</b>.</p>","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"1358863X251336736"},"PeriodicalIF":3.0,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144112086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Quantification of arterial calcification in peripheral artery disease and its association with amputation and/or mortality: A systematic review.","authors":"Jenny Woo, Arash Fereydooni, Janhavi Patel, Anoushka Lakshmi, Sujin Lee, Amber Trickey, Shipra Arya","doi":"10.1177/1358863X251334572","DOIUrl":"https://doi.org/10.1177/1358863X251334572","url":null,"abstract":"<p><p>Arterial calcification is prevalent in peripheral artery disease (PAD), especially among patients with advanced age, diabetes, or renal disease. Peripheral arterial calcium score (PACS) is an emerging tool to quantify calcification in peripheral arteries and predict outcomes such as amputation and mortality. This systematic review evaluates PACS methodologies and its association with these adverse outcomes. In a comprehensive search of Embase, MEDLINE, and PubMed from January 1991 to January 2025, 1092 studies were retrieved, of which 17 met the inclusion criteria. Computed tomography and X-ray imaging were the main imaging modalities used to detect calcification through a variety of PACS. A higher PACS was linked to increased risk of amputation and/or mortality. PACS holds potential for predicting outcomes in PAD, particularly amputation and mortality. Standardization of PACS methods is needed to enhance its clinical utility and integration into practice.</p>","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"1358863X251334572"},"PeriodicalIF":3.0,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144039835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cumulative impact of procedural and anatomical factors on in-hospital bleeding complications in endovascular therapy for lower-extremity artery disease: A nationwide registry study in Japan.","authors":"Takuya Nakahashi, Mitsuyoshi Takahara, Osamu Iida, Shun Kohsaka, Yoshimitsu Soga, Kazunori Horie, Kenji Sakata, Masayuki Takamura, Tetsuya Amano, Ken Kozuma","doi":"10.1177/1358863X251320113","DOIUrl":"10.1177/1358863X251320113","url":null,"abstract":"<p><p><b>Background:</b> Although bleeding is a common procedure-related adverse event following endovascular therapy (EVT), limited data exist regarding the procedural and anatomical factors associated with its complications in patients with lower-extremity artery disease (LEAD) undergoing EVT. <b>Methods:</b> Data were extracted from a nationwide Japanese EVT registry of 73,990 patients who underwent EVT for symptomatic LEAD between January 2021 and December 2022. The primary outcome measure was in-hospital bleeding complications, including access site bleeding, nonaccess site bleeding, and hemorrhagic stroke. <b>Results:</b> The mean age of the patients was 75 ± 9 years, and 69% were men. In-hospital bleeding complications were observed in 613 (0.8%) patients. Logistic regression analysis demonstrated significant associations between bleeding complications and the following procedural, anatomical, and pharmacological variables: emergent revascularization (odds ratio [OR]: 1.90, 95% CI: 1.29-2.79), multiple approach sites (OR: 2.46, 95% CI: 2.00-3.01), bilateral arterial calcification (OR: 1.46, 95% CI: 1.19-1.79), chronic occlusion (OR: 1.53, 95% CI: 1.28-1.83), dual antiplatelet therapy (OR: 1.70, 95% CI: 1.27-2.28), and oral anticoagulant (OR: 1.63, 95% CI: 1.31-2.03). The adjusted incidence of in-hospital bleeding was 0.59% (95% CI: 0.51-0.68%) in patients with one of the identified procedural and anatomical risk factors, 0.96% (95% CI: 0.82-1.13%) in patients with two factors, and 2.40% (95% CI: 1.88-3.05%) in patients with three or four factors. <b>Conclusions:</b> Procedural and anatomical factors as well as antithrombotic strategies were significantly associated with an increased risk of in-hospital bleeding in patients with LEAD who underwent EVT.</p>","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"155-161"},"PeriodicalIF":3.3,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143483919","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vascular MedicinePub Date : 2025-04-01Epub Date: 2025-01-06DOI: 10.1177/1358863X241306406
Toluwani Odu, Gaëlle Romain, Lindsey Scierka, Jacob Cleman, Santiago Callegari, Francky Jacque, Carlos Mena-Hurtado, Kim G Smolderen
{"title":"Interaction of anxiety symptoms with peripheral artery disease treatment strategies and health status outcomes.","authors":"Toluwani Odu, Gaëlle Romain, Lindsey Scierka, Jacob Cleman, Santiago Callegari, Francky Jacque, Carlos Mena-Hurtado, Kim G Smolderen","doi":"10.1177/1358863X241306406","DOIUrl":"10.1177/1358863X241306406","url":null,"abstract":"","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"216-217"},"PeriodicalIF":3.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142932716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vascular MedicinePub Date : 2025-04-01Epub Date: 2025-04-23DOI: 10.1177/1358863X251326568
Tabitha N Lobo, Alexandra Solomon, Christopher J Abularrage, Elizabeth V Ratchford
{"title":"Vascular Disease Patient Information Page: Visceral artery aneurysms.","authors":"Tabitha N Lobo, Alexandra Solomon, Christopher J Abularrage, Elizabeth V Ratchford","doi":"10.1177/1358863X251326568","DOIUrl":"https://doi.org/10.1177/1358863X251326568","url":null,"abstract":"","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":"30 2","pages":"265-271"},"PeriodicalIF":3.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144001822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vascular MedicinePub Date : 2025-04-01Epub Date: 2025-03-03DOI: 10.1177/1358863X251323516
Saturne Barthold, Eduarda Oz Minin, Luís Frs Carvalho-Romano, Edmilson R Marques, Layde R Paim, Elisangela Cp Lopes, Camila Fl Vegian, José A Pio-Magalhães, José R Matos-Souza, Otavio R Coelho-Filho, Andrei C Sposito, Wilson Nadruz, Roberto Schreiber
{"title":"Association of oxidized LDL with carotid wall layers in hypertensive patients.","authors":"Saturne Barthold, Eduarda Oz Minin, Luís Frs Carvalho-Romano, Edmilson R Marques, Layde R Paim, Elisangela Cp Lopes, Camila Fl Vegian, José A Pio-Magalhães, José R Matos-Souza, Otavio R Coelho-Filho, Andrei C Sposito, Wilson Nadruz, Roberto Schreiber","doi":"10.1177/1358863X251323516","DOIUrl":"10.1177/1358863X251323516","url":null,"abstract":"","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"213-215"},"PeriodicalIF":3.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vascular MedicinePub Date : 2025-04-01Epub Date: 2025-01-17DOI: 10.1177/1358863X241309834
Angelo Nigro
{"title":"Images in Vascular Medicine: Severe acrocyanosis with capillaroscopic findings.","authors":"Angelo Nigro","doi":"10.1177/1358863X241309834","DOIUrl":"10.1177/1358863X241309834","url":null,"abstract":"","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"263-264"},"PeriodicalIF":3.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vascular MedicinePub Date : 2025-04-01Epub Date: 2025-01-06DOI: 10.1177/1358863X241308208
Hisato Takagi
{"title":"Images in Vascular Medicine: Naked and clothed right coronary artery in aortic intramural hematoma.","authors":"Hisato Takagi","doi":"10.1177/1358863X241308208","DOIUrl":"10.1177/1358863X241308208","url":null,"abstract":"","PeriodicalId":23604,"journal":{"name":"Vascular Medicine","volume":" ","pages":"261-262"},"PeriodicalIF":3.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142932697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}