Vestnik otorinolaringologii最新文献

{"title":"[Features of inflammatory endotypes and phenotypes in chronic rhinosinusitis].","authors":"A V Chufistova, E V Shabaldina, A V Bedareva, I N Vakhrameev, N A Abramova, A V Shabaldin","doi":"10.17116/otorino20248904160","DOIUrl":"10.17116/otorino20248904160","url":null,"abstract":"<p><p>Recently, significant progress has been made in identifying the cellular and molecular mechanisms responsible for the pathogenesis of chronic rhinosinusitis (CRS). Cohort studies of CRS have led to advances in the clinical understanding of this disease. New therapeutic agents have been approved or are undergoing clinical trials to expand treatment options for this disease. One of the promising areas in medicine is the provision of personalized clinical care. From this perspective, CRS can be divided into three different endotypes depending on the type of underlying inflammatory response. In the United States, CRS with and without nasal polyps is predominantly characterized as the second inflammatory endotype. CRS with nasal polyps (about 17%) and without nasal polyps (up to 20%) belongs to the 1st and 3rd inflammatory endotypes, respectively. And if for the second inflammatory endotype the effectiveness of targeted biological therapy is beyond doubt, then for the first and third inflammatory endotypes the principles of such conservative therapy are under active development. Moreover, large validated studies to confirm associations between CRS phenotypes and endotypes, as well as to find effective biological markers of inflammatory endotypes, remain to be performed.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"89 4","pages":"60-67"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142018739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Choanoplasty in children of the first year of life: new opportunities and rehabilitation without stents].","authors":"N A Daikhes, M M Polunin, A I Asmanov, O A Breeva, N D Pivneva","doi":"10.17116/otorino20248902140","DOIUrl":"10.17116/otorino20248902140","url":null,"abstract":"<p><p>The article presents literature and our own data on surgical treatment and options for solving the problem of restenosis for congenital choanal atresia in children under one year of age. A new stentless choanoplasty technique using fibrin glue for fixation of posterior septal flaps is presented. This method has patent No. 2789967 dated February 14, 2023.</p><p><strong>Objective: </strong>Evaluation of the effectiveness of the choanoplasty method using fibrin glue for fixation of flaps without the use of a stent in children of the first year of life with choanal atresia.</p><p><strong>Material and methods: </strong>For the period from 2019 to 2023, a team of authors in the Department of Otorhinolaryngology of the Veltishchev Research Clinical Institute of Pediatrics and Pediatric Surgery operated on 34 patients under the age of one year with a diagnosis of choanal atresia using this choanoplasty technique.</p><p><strong>Results: </strong>The results of this new surgical technique using fibrin glue are presented. Endoscopy of the nasal cavity and choanal area in all 34 patients during follow-up (from 1 to 2 years) showed no signs of restenosis.</p><p><strong>Conclusion: </strong>The proposed method of choanoplasty without the use of stents with fixation of mucosal flaps with fibrin glue has proven itself well and can be used in children at any age, can be one of the ways to solve the problem of restenosis and seems to us to be the method of choice in the treatment of choanal atresia.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"89 2","pages":"40-45"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141162692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Features of olfactory impairment connected with trigeminal nerve system].","authors":"A I Kryukov, N L Kunelskaya, Z O Zaoeva, E V Baybakova, M A Chugunova, A S Tovmasyan, S A Panasov, E S Yanyushkina, E A Manaenkova, Ya Yu Nikitkina, T N Panova, A E Kishinevskii","doi":"10.17116/otorino20248902133","DOIUrl":"10.17116/otorino20248902133","url":null,"abstract":"<p><p>Data on the state of sense of smell in patients who had a new coronavirus infection caused by the SARS-CoV-2 virus are currently reduced because of the impairment of the olfactory nerve system. There are practically no results in studies of disorders in the trigeminal nerve system.</p><p><strong>Objective: </strong>Qualitative assessment of olfactory disorders after COVID-19 according to the system of olfactory and trigeminal nerves with a targeted assessment of the functional component of olfactory disorders.</p><p><strong>Material and methods: </strong>We examined 40 patients aged 19 to 66 who had a coronavirus infection. All patients underwent neurological, otorhinolaryngological examinations, olfactometry, filled out the hospital anxiety and depression scale.</p><p><strong>Results: </strong>Anosmia was diagnosed in 5 (12.5%) patients, hyposmia in 21 (52.5%) patients, and normosmia in 14 (35%) patients. Formed: the 1st group - 14 patients (35%) with normogram according to olfactometry; the 2nd group - 26 patients (65%) with anosmia/hyposmia. In the 1st group, disorders of the anxiety-depressive spectrum were significantly more common. In the 2nd group, a low identification of odors was found, lying in the spectrum of fresh, sharp, unpleasant, irritating, compared with sweet and pleasant or neutral, which indicates a predominant lesion of the trigeminal system.</p><p><strong>Conclusion: </strong>In patients with complaints of impaired sense of smell after undergoing COVID-19, the possible functional nature of anosmia/hyposmia should be taken into account, which requires the referral of such patients to psychotherapeutic specialists, and the possible entry of olfactory disorders into the 'trigeminal' spectrum.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"89 2","pages":"33-39"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141162741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Development and safety study of a 3D printed middle turbinate splint].","authors":"A I Kryukov, A S Tovmasyan, A E Kishinevskii, V V Mosin, P L Chumakov, V V Yanovsky, N V Shvedov","doi":"10.17116/otorino20248904130","DOIUrl":"https://doi.org/10.17116/otorino20248904130","url":null,"abstract":"<p><p>Adhesion of the middle turbinate to the lateral wall of the nasal cavity and synechia of the middle meatus are one of the common reasons for the failure of surgical interventions for chronic sinusitis. The use of specially shaped intranasal splints can solve the problem of preventing synechiae in the postoperative period. Many different devices and approaches have been proposed to prevent the development of this category of complications. This study proposes an anatomical version of the splint for the middle turbinate, developed using 3D computer modeling technologies followed by printing from a biocompatible elastic material on a Formlabs 3BL 3D printer. The shape and size of the splint were developed based on the analysis of computed tomography data of 50 adult patients. The safety of the developed device was studied in a group of 20 volunteers in whom the developed splint was installed on one side of the nasal cavity for 2 weeks after bilateral surgery. According to endoscopic examination and patient questionnaires, the developed splint did not cause local or systemic allergic reactions and did not create additional discomfort for the patient in the postoperative period. Installing a splint helped prevent the formation of synechiae. However, to determine clinical effectiveness, a study with a larger sample of patients is required.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"89 4","pages":"30-36"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142018802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Modern methods of diagnosis and treatment of lacrimal stenosis. Literature review].","authors":"M M Magomedov, T N Zhogoleva, M B Davtian, N M Magomedova, Sh Yu Avkaeva","doi":"10.17116/otorino20248905158","DOIUrl":"https://doi.org/10.17116/otorino20248905158","url":null,"abstract":"<p><p>This analysis is based on the study of Russian and foreign literature sources devoted to both high-tech and routine methods of studying the lacrimal drainage system, as well as the description of modern methods of conservative and surgical treatment of lacrimal stenosis. This article gives information about advantages and disadvantages of each of the methods of diagnosis and treatment of obliteration of the lacrimal tract, highlights the questions of their usage in dacryology.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"89 5","pages":"58-62"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142639900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Optimized interdisciplinary approach in the treatment of maxillary sinus upper wall fractures in children].","authors":"D I Konstantinov, M A Erashov, O A Denisova, M M Polunin, Yu L Soldatsky, A A Polyakov, E D Gorbunova, L B Kononov, S R Edgem","doi":"10.17116/otorino20248905129","DOIUrl":"https://doi.org/10.17116/otorino20248905129","url":null,"abstract":"<p><p>Rehabilitation of children with fractures of the upper wall of the maxillary sinus remains relevant due to the need for a balanced approach to treatment, which would take into account both the features of traumatic injuries in children and the specifics of their age development. The article describes a technique for combined (endoscopic transnasal and transconjunctival) surgical treatment of children with fractures of the upper wall of the maxillary sinus using a sinus balloon catheter.</p><p><strong>Objective: </strong>To study the effectiveness and safety of the functional method of treating fractures of the upper wall of the maxillary sinus using endoscopic sinus surgery and a sinus balloon catheter.</p><p><strong>Material and methods: </strong>The study included 106 children aged 5 to 17 years with fractures of the upper wall of the maxillary sinus who underwent surgical treatment at the Morozovskaya Children's City Clinical Hospital from 2018 to 2023. Treatment was administered to children with pronounced bone defects, combined injuries, and ophthalmological symptoms.</p><p><strong>Results: </strong>As a result of the treatment, all 106 children showed no hernial protrusions in the lumen of the maxillary sinus on control tomograms. There were no cases of decreased visual acuity or impaired eye movement function during follow-up by an ophthalmologist. Complete consolidation of bone fragments with restoration of the integrity of the sinus wall was achieved in 91.5% of patients; in the remaining 8.5% of cases, a bone defect in the upper wall of the maxillary sinus up to 1-2 mm in diameter was preserved according to CT data, which clinically did not manifest itself.</p><p><strong>Conclusion: </strong>The proposed technique using a sinus balloon catheter is preferable for children with fractures of the upper wall of the maxillary sinus. Due to the functionality of access, absence of the need for endoprosthetics of the bone walls of the sinus and orbit, minimization of disruptions to the growth zones of the facial skeleton, and achieving good functional and cosmetic results.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"89 5","pages":"29-34"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142639905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Experience of transnasal endoscopic drainage of rhinosinusogenic frontal lobe abscess].","authors":"V A Moskalev, D S Chinarev, R V Kasich, V Yu Shumov","doi":"10.17116/otorino20248906189","DOIUrl":"10.17116/otorino20248906189","url":null,"abstract":"<p><p>Intracranial complications in inflammatory diseases of the ear and nose are currently not frequent, but their lethality remains high. The choice of optimal, safe and effective access in surgical treatment of purulent-inflammatory intracranial complications remains a subject of discussions and is based on an individual approach, depends on the volume, localization and clinical condition of the patient.</p><p><strong>Objective: </strong>To demonstrate a clinical case of successful drainage of the brain frontal lobe abscess using endoscopic transnasal access under the control of the navigation system.</p><p><strong>Conclusion: </strong>In case of abscess localization at the skull base and projection of the roof of the lattice labyrinth, drainage of the nidus can be performed using endoscopic endonasal access. Especially when simultaneous sanation of the primary focus is necessary, which allows avoiding neurosurgical intervention.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"89 6","pages":"89-94"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142898557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Bilateral vestibulopathy and sensorineural hearing loss in necrobiotic xanthogranuloma, multiple myeloma and amiloidosis].","authors":"E V Reznik, A L Guseva, A A Yasnovskaya, T L Nguyen, L M Mikhaleva, Z V Gioeva, E V Baybakova, A P Smirnov","doi":"10.17116/otorino20248902182","DOIUrl":"10.17116/otorino20248902182","url":null,"abstract":"<p><p>This article describes a rare case of necrotic xanthogranuloma in a 46-year-old patient who presented with the development of periorbital xanthelasms, progressive bilateral sensorineural hearing loss and bilateral vestibulopathy, followed by multiple myeloma and amyloidosis. For several years, the patient underwent standard rehabilitation for chronic sensorineural hearing loss and was fitted with a hearing aid. During hospitalisation for exacerbation of chronic bronchitis, monoclonal gammopathy was identified, and later, after careful examination and repeated biopsies, necrotic xanthogranuloma, multiple myeloma and AL-amyloidosis were confirmed. Targeted immunochemotherapy resulted in improvement of hearing and significant recovery of the vestibuloocular reflex bilaterally.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"89 2","pages":"82-87"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141162685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[Intraosseous cavernous hemangioma of the middle turbinate. Clinical cases].","authors":"A S Tovmasyan, E I Zelikovich, A G Kurilenkova, K E Klimenko, I G Kolbanova, V G Shatalov, E V Filina, A E Kishinevskii, S R Ramazanov","doi":"10.17116/otorino20248901145","DOIUrl":"https://doi.org/10.17116/otorino20248901145","url":null,"abstract":"<p><p>Intraosseous vascular pathology of the turbinates is extremely rare in the practice of an otorhinolaryngologist and can be presented in various histopathological variants. The article presents two clinical cases in which an intraosseous cavernous hemangioma was hidden under the mask of a hypertrophied middle turbinate. The final diagnosis was established by the results of histological examination. The analysis of these clinical cases indicates that, despite the low prevalence, atypical clinical and CT picture, intraosseous formations of the nasal cavity can be of a vascular nature and certainly require a comprehensive examination, including CT, CT with contrast and/or MRI of the nose and paranasal sinuses. These clinical observations indicate that preliminary embolization of feeding vessels before surgical treatment is not required.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"89 1","pages":"45-51"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140176700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"[The evolution of ideas about cyst-like stretching of the paranasal sinuses. Part I].","authors":"A I Kryukov, A S Tovmasyan, K E Klimenko, E I Zelikovich, A G Kurilenkova, A E Kishinevskii, V V Mosin, N V Shvedov","doi":"10.17116/otorino20248901128","DOIUrl":"https://doi.org/10.17116/otorino20248901128","url":null,"abstract":"<p><p>Treatment of patients with severe chronic and recurrent forms of sinusitis, complicated by pathological stretching of the paranasal sinuses, is not a trivial task. This is especially true for those clinical cases where a pathological increase in the size of the sinus leads to widespread destruction of its walls and may be accompanied by serious complications from adjacent structures. The paper presents an analytical review of publications on the topic of pathological stretching of the paranasal sinuses. Potential factors influencing the development of this pathology, mechanisms of pathogenesis and classification options are described in detail. Modern approaches are considered in the surgical treatment of this pathology, which can be carried out in one or two stages, depending on the presence of secondary aesthetic defects.</p>","PeriodicalId":23575,"journal":{"name":"Vestnik otorinolaringologii","volume":"89 1","pages":"28-31"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140176703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}