Urologia JournalPub Date : 2026-08-01Epub Date: 2026-03-29DOI: 10.1177/03915603261433615
Ilaria Elena Zais, Nicolò Schifano, Sara Baldini, Matteo Coschignano, Alessio Villano, Paolo Capogrosso, Gabriele Antonini, Giuseppe Gianesini, Federico Dehò
{"title":"Testicular torsion among adults: An extremely rare or an extremely under-estimated issue? A case report and a narrative review of the literature.","authors":"Ilaria Elena Zais, Nicolò Schifano, Sara Baldini, Matteo Coschignano, Alessio Villano, Paolo Capogrosso, Gabriele Antonini, Giuseppe Gianesini, Federico Dehò","doi":"10.1177/03915603261433615","DOIUrl":"10.1177/03915603261433615","url":null,"abstract":"<p><p>Testicular torsion is an uncommon urological emergency, rare in men over 50 years of age. Its nonspecific clinical presentation often leads to misdiagnosis as more frequent conditions such as epididymo-orchitis, resulting in delayed treatment and poor testicular salvage outcomes. We report the case of a 54-year-old man presenting with right-sided scrotal pain and swelling, initially managed for epididymitis. Due to persistent symptoms despite antibiotic therapy, a scrotal ultrasound was performed, revealing absence of arterial blood flow in the right testis. Surgical exploration confirmed testicular necrosis secondary to a 720° spermatic cord torsion, necessitating right orchiectomy. A narrative literature review was also conducted via MEDLINE/PubMed and Scopus to identify relevant studies on adult testicular torsion: despite the narrative nature of our study, a reproducible approach has been adopted to identify the relevant studies for the final review. The Joanna Briggs Institute Checklist has been used to estimate the quality of the included articles. Nineteen studies were selected for inclusion after the selection process. The existing literature largely consists of anecdotal case reports and small case series, with most cases reporting delayed presentation and resulting orchiectomy. Unlike pediatric populations, where the clinical presentation is often more dramatic and recognizable, testicular torsion in adults may present more subtly, leading to misinterpretation and delays in surgical intervention. Late presentation to medical attention and reliance on conservative management strategies can delay the diagnosis of testicular torsion in adults. Although Doppler ultrasound serves as a helpful diagnostic adjunct, prompt surgical exploration remains essential when clinical suspicion is high. In conclusion, clinicians should maintain a high index of suspicion for testicular torsion in all patients presenting with acute scrotal pain, regardless of age. Early recognition and timely surgical intervention are crucial not only to preserve testicular viability but also to safeguard long-term physical, reproductive, and psychological health.</p>","PeriodicalId":23574,"journal":{"name":"Urologia Journal","volume":" ","pages":"492-498"},"PeriodicalIF":1.3,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147575591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Urologia JournalPub Date : 2026-08-01Epub Date: 2026-03-13DOI: 10.1177/03915603261428903
Marwan Alkassis, Nour Khalil, Fadi Farah, Georges Abi Tayeh, Charbel Chalouhy, Maroun Moukarzel
{"title":"Early versus standard unclamping of the renal artery in laparoscopic partial nephrectomy: The Lebanese experience.","authors":"Marwan Alkassis, Nour Khalil, Fadi Farah, Georges Abi Tayeh, Charbel Chalouhy, Maroun Moukarzel","doi":"10.1177/03915603261428903","DOIUrl":"10.1177/03915603261428903","url":null,"abstract":"<p><strong>Objectives: </strong>To assess the feasibility and safety of early unclamping of the renal artery during laparoscopic partial nephrectomy (LPN) for localized renal tumors, by comparing the perioperative outcomes of early versus standard unclamping techniques in a tertiary care center in Lebanon.</p><p><strong>Material and methods: </strong>This retrospective study included patients who underwent pure or hand-assisted LPN between 2017 and 2020. Patients were categorized into early unclamping (EUC)-where the renal artery was unclamped after placement of the initial sutures on the tumor bed-and standard unclamping (SUC)-where clamping was maintained until renorrhaphy was complete. Perioperative parameters, tumor characteristics, kidney function, complication rates, and pathological outcomes were compared. Multivariable analysis, sensitivity analysis, and stratification were conducted to explore predictors of warm ischemia time (WIT), complications, and other outcomes.</p><p><strong>Results: </strong>Forty-nine patients were included (37 SUC, 12 EUC). EUC was associated with a significantly shorter warm ischemia time compared with SUC (15 min vs 25 min, <i>p</i> < 0.001), with a trend toward shorter operative time. Complication rates, transfusion requirements, and positive surgical margins did not differ significantly between groups. Multivariable analysis suggested that EUC was independently associated with shorter warm ischemia time, while tumor size appeared to be the main predictor of complications. Sensitivity analysis also indicated an association between tumor size and complications, and stratified analysis suggested that complications tended to occur more frequently in complex tumors.</p><p><strong>Conclusions: </strong>Early unclamping in LPN is a feasible and safe technique that reduces WIT without compromising visibility during tumor resection or renorrhaphy. This strategy theoretically supports favorable functional and oncologic outcomes, though definitive evidence is limited by the lack of long-term follow-up. Larger prospective studies are needed to confirm these potential benefits.</p>","PeriodicalId":23574,"journal":{"name":"Urologia Journal","volume":" ","pages":"485-491"},"PeriodicalIF":1.3,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147445397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Urologia JournalPub Date : 2026-08-01Epub Date: 2026-03-16DOI: 10.1177/03915603261427632
Mehmet Özen, İlayda Özden Yıldırım, Mustafa Koray Kırdağ, Mustafa Aydın, Uğur Öztürk, Mustafa Kemal Atilla
{"title":"Reliability of InVesalius in kidney stone volume assessment: Correlation with 3D slicer and ellipsoid calculations.","authors":"Mehmet Özen, İlayda Özden Yıldırım, Mustafa Koray Kırdağ, Mustafa Aydın, Uğur Öztürk, Mustafa Kemal Atilla","doi":"10.1177/03915603261427632","DOIUrl":"10.1177/03915603261427632","url":null,"abstract":"<p><strong>Introduction: </strong>Accurate assessment of kidney stone burden is essential for clinical decision-making. This study aimed to evaluate the efficacy of \"InVesalius,\" an open-source 3D imaging software, for stone volume measurement and compare its performance with 3D Slicer software and the traditional ellipsoid formula.</p><p><strong>Methods: </strong>In this prospective study, 65 patients with kidney stones confirmed by non-contrast enhanced computed tomography were enrolled between January and April 2025. Stone volumes were calculated using \"InVesalius,\" \"3D Slicer\" (Kidney Stone Calculator extension), and the ellipsoid formula. Correlations between methods were assessed with Spearman's rank-order correlation.</p><p><strong>Results: </strong>\"InVesalius\" and \"3D Slicer\" showed highly comparable results (<i>r</i> = 0.99, <i>p</i> < 0.001), both consistently yielding slightly larger volumes than the ellipsoid formula. All methods demonstrated strong correlations, though discrepancies were most evident between the ellipsoid formula and the 3D-based methods.</p><p><strong>Conclusions: </strong>\"InVesalius\" provides reliable kidney stone volume measurements comparable to 3D Slicer and superior to the ellipsoid formula. Its free availability, DICOM compatibility, and ease of use make it particularly valuable in clinical and research environments lacking access to commercial imaging tools.</p>","PeriodicalId":23574,"journal":{"name":"Urologia Journal","volume":" ","pages":"360-363"},"PeriodicalIF":1.3,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147469242","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Urologia JournalPub Date : 2026-08-01Epub Date: 2026-04-24DOI: 10.1177/03915603261441148
Clara Helene Glazer, Sara Afghan Tolouee, Rie Seifert, Christian Fuglesang Skjødt Jensen, Mikkel Fode
{"title":"Platelet-rich plasma therapy in benign bladder diseases: A systematic review of the literature.","authors":"Clara Helene Glazer, Sara Afghan Tolouee, Rie Seifert, Christian Fuglesang Skjødt Jensen, Mikkel Fode","doi":"10.1177/03915603261441148","DOIUrl":"10.1177/03915603261441148","url":null,"abstract":"<p><p>Platelet-rich plasma (PRP) is an emerging regenerative therapy increasingly explored in urology. This systematic review assessed evidence on intravesical PRP for benign bladder diseases, including bladder pain syndrome (BPS), recurrent urinary tract infections (UTI), overactive bladder (OAB), and ketamine-induced bladder dysfunction (KIBD). The review followed PRISMA guidelines and was registered in PROSPERO (CRD42024563156). Searches were conducted in PubMed, Scopus, and the Cochrane Library in August 2024 and updated in April 2025. Eligible studies were prospective or retrospective clinical trials evaluating PRP for BPS, recurrent UTI, OAB, or KIBD. Two reviewers screened articles, extracted data, and assessed bias risk using ROBINS-I. Extracted variables included study design, population, PRP preparation, administration method, outcomes, follow-up, and safety. Owing to methodological heterogeneity, findings were synthesized descriptively. Seven studies involving 284 patients were included. Six assessed PRP for BPS and one for recurrent UTI; none examined OAB or KIBD. PRP was generally well tolerated and associated with improvements in pain and urinary symptoms. Current evidence suggests possible benefit of PRP in BPS and recurrent UTI; however, conclusions are severely limited by small sample sizes, lack of control groups and methodological heterogeneity. Larger randomized trials are needed before PRP can be adopted into clinical practice.</p>","PeriodicalId":23574,"journal":{"name":"Urologia Journal","volume":" ","pages":"338-346"},"PeriodicalIF":1.3,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147782408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Factors that lead to returns to emergency department after urological procedures.","authors":"Yahya Ghazwani, Ali Alyami, Ali Alothman, Abdulaziz Almanie, Ebtesam Almajed, Sadem AlZayed, Rayan Almasari, Ayah Farghal, Waleed Alharthi, Nasser Albqami, Fatimah Khalid Alkhunaizi","doi":"10.1177/03915603261430514","DOIUrl":"10.1177/03915603261430514","url":null,"abstract":"<p><strong>Purpose: </strong>Many urological procedures are performed as daycare surgeries, allowing for same-day patient discharge. However, this may result in a higher incidence of unplanned emergency department (ED) visits. This study investigates factors contributing to ED return after urological procedures within a 90-day period.</p><p><strong>Methods: </strong>This retrospective study analyzed data between January 1, 2018, and January 1, 2022, at a tertiary institution in Riyadh, Saudi Arabia. The analysis assessed parameters associated with complications and explored factors related to ED revisit. Logistic regression analyzes evaluated associations between predictors and ED return rates.</p><p><strong>Results: </strong>A total of 797 cases were reviewed, with 218 (27.4%) patients returning to the ED. The mean age of participants was 49.7 years. The majority were male (73.3%). Primary diagnoses included ureter (30.5%), renal (21.6%), and bladder conditions (14.9%). Urinary-related issues accounted for the most common reasons for ED returns (44.0%), followed by pain-related (30.3%) and infection-related causes (11.5%). Univariate analysis indicated that female sex (UOR: 1.53), length of stay (UOR: 1.26), and ASA score (UOR: 1.32) were associated with an increased likelihood of returning to the ED. Multivariate analysis confirmed that female sex (AOR: 1.52), length of stay (AOR: 1.81), and ASA score (AOR: 1.40) significantly predicted ED revisit.</p><p><strong>Conclusion: </strong>This study highlights the importance of addressing urinary-related and pain symptoms in postoperative care to reduce ED return. Identifying significant predictors, such as female sex, length of stay, and ASA score, underscores the need for targeted interventions to enhance patient outcomes and reduce unnecessary healthcare utilization.</p>","PeriodicalId":23574,"journal":{"name":"Urologia Journal","volume":" ","pages":"474-484"},"PeriodicalIF":1.3,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147487471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Urologia JournalPub Date : 2026-08-01Epub Date: 2026-03-07DOI: 10.1177/03915603261426555
Coşkun Bostancı, Kazım Erdem
{"title":"Evaluation of the association between prostate-specific antigen density and systematic prostate biopsy pathological results.","authors":"Coşkun Bostancı, Kazım Erdem","doi":"10.1177/03915603261426555","DOIUrl":"10.1177/03915603261426555","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the correlation between pre-biopsy prostate-specific antigen (PSA) density (PSA-d) and International Society of Urological Pathology (ISUP) grade groups obtained from systematic transrectal prostate biopsies (TRUS-B). The secondary objective was to compare the diagnostic accuracy of PSA-d and PSA for prostate cancer (PCa) detection.</p><p><strong>Methods: </strong>A retrospective study was conducted on 1094 patients with PSA levels between 2.5 and 25 ng/ml who underwent TRUS-B between 2016 and 2024. Patients were classified into four groups based on PSA-d levels: <0.10, 0.10-0.14, 0.15-0.20, and >0.20 ng/ml/cc. Detection of the ISUP grade for each group was obtained and compared among the groups. Diagnostic accuracy was assessed using receiver operating characteristic (ROC) curve analysis and the area under the curve (AUC).</p><p><strong>Results: </strong>PCa detection rates increased with PSA-d, from 14.2% (<0.10 ng/ml/cc) to 85.9% (>0.20 ng/ml/cc), while clinically significant PCa rates ranged from 5.9% to 68.4% across the same PSA-d levels. Higher PSA-d levels were significantly associated with elevated ISUP grade groups. However, for ISUP grade group 1, the only significant difference was between patients with PSA-d <0.10 ng/ml/cc and those with PSA-d ⩾0.10 ng/ml/cc. PSA-d demonstrated superior diagnostic accuracy (AUC = 0.821) compared with PSA (AUC = 0.654).</p><p><strong>Conclusion: </strong>PSA-d is a reliable marker for predicting PCa aggressiveness and has better diagnostic accuracy than PSA. Incorporating PSA-d into clinical decision-making may enhance the detection of clinically significant PCa, particularly in resource-limited settings where advanced imaging modalities are unavailable.</p>","PeriodicalId":23574,"journal":{"name":"Urologia Journal","volume":" ","pages":"426-433"},"PeriodicalIF":1.3,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147372743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bladder Urothelial Neoplasms Profile in Dr. Soetomo General Academic Hospital Surabaya: Retrospective Study during 2013-2023.","authors":"Khafidhotul Ilmiah, Irene Lingkan Parengkuan, Anny Setijo Rahaju, Gondo Mastutik, Wahjoe Djatisoesanto","doi":"10.1177/03915603261434799","DOIUrl":"10.1177/03915603261434799","url":null,"abstract":"<p><strong>Background: </strong>Bladder urothelial neoplasms were the most common type of tumor in the urinary tract. These tumors often recur and are progressive. Therefore, it is necessary to analyze the patient's profile. The aim is to examine the clinicopathologic character with a retrospective study.</p><p><strong>Method: </strong>This is a descriptive study with retrospective approach. Data were collected from the histopathological diagnosis of urothelial neoplasms at Laboratory of Anatomical Pathology in Dr. Soetomo General Academic Hospital, Surabaya, from 2013 to 2023.</p><p><strong>Result: </strong>There were 618 people with bladder urothelial neoplasms. Males predominate in this research (87.5%), and 32% occur between the ages of 51 and 60. Procedure used for diagnosing was 46.6% by TURB. High-grade tumors constituted 81% and 92.6% were already invasive, with 58.4% being MIBC.</p><p><strong>Discussion: </strong>This study exhibits a higher prevalence of urothelial neoplasms in males, likely due to smoking and androgen receptor influence. Most individuals were diagnosed after 50 years old. The majority of them already have high-grade, muscle-invasive tumors, which may have worse prognosis than low-grade, NMIBC tumors.</p><p><strong>Conclusion: </strong>There was male predominance in urothelial bladder neoplasms. Most ages were after 50 years. The majority of tumors were high grade and already muscle invasive (at least pT2).</p>","PeriodicalId":23574,"journal":{"name":"Urologia Journal","volume":" ","pages":"384-388"},"PeriodicalIF":1.3,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147575661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Urologia JournalPub Date : 2026-08-01Epub Date: 2026-04-28DOI: 10.1177/03915603261445157
Emilio Sacco, Francesco Pio Bizzarri
{"title":"Comment on: \"Comparison of long-term survival for muscle-invasive bladder cancer patients who underwent bladder preservation therapy and radical cystectomy: A systematic review and meta-analysis\".","authors":"Emilio Sacco, Francesco Pio Bizzarri","doi":"10.1177/03915603261445157","DOIUrl":"10.1177/03915603261445157","url":null,"abstract":"","PeriodicalId":23574,"journal":{"name":"Urologia Journal","volume":" ","pages":"537-538"},"PeriodicalIF":1.3,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147782591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diagnostic accuracy and reliability of VI-RADS in assessing muscle invasion in bladder cancer: Insight from a prospective tertiary care study.","authors":"Anupam Shukla, Hiralal, Himanshu Raj, Sanjoy Surekha, Uday Pratap Singh","doi":"10.1177/03915603261429445","DOIUrl":"10.1177/03915603261429445","url":null,"abstract":"<p><strong>Background: </strong>Multiparametric magnetic resonance imaging (mp-MRI) has emerged as a promising technique for evaluating the extent of bladder cancer, particularly for assessing muscle invasion. The Vesical Imaging Reporting and Data System (VI-RADS), introduced in 2018, aims to standardize the interpretation of mp-MRI for staging bladder tumors. This study investigates the diagnostic accuracy of VI-RADS in predicting detrusor muscle involvement preoperatively.</p><p><strong>Objective: </strong>To assess the diagnostic performance of VI-RADS scoring in determining muscle invasion in bladder cancer patients prior to surgical intervention.</p><p><strong>Methods: </strong>This prospective study enrolled 62 patients between June 2021 and April 2023 who presented with bladder masses. Each underwent mp-MRI followed by surgical treatment, including either TURBT or radical cystectomy. Two radiologists independently evaluated images using VI-RADS scoring. The results were compared with final histopathological findings to determine diagnostic accuracy.</p><p><strong>Results: </strong>VI-RADS scores of 4 and 5 were observed in 10 (16%) and 19 (30.6%) patients respectively; scores of 3, 2, and 1 were assigned to 3 (4.8%), 25 (40.3%), and 5 (8.0%) patients, respectively. Histopathological evaluation confirmed muscle invasion in 29 patients (46.77%) and non-muscle-invasive disease in 33 (53.22%). The mp-MRI demonstrated a sensitivity of 93.10%, specificity of 93.94%, and an overall accuracy of 93.54% in detecting muscle invasion.</p><p><strong>Conclusion: </strong>Mp-MRI interpreted using the VI-RADS system offers more than 90% sensitivity and specificity for detecting muscle invasion in bladder cancer. VI-RADS may serves as a valuable tool for preoperative staging, potentially optimizing treatment planning and reducing unnecessary restaging TURBT.</p>","PeriodicalId":23574,"journal":{"name":"Urologia Journal","volume":" ","pages":"364-369"},"PeriodicalIF":1.3,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147445406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}