{"title":"Role of rectal swab cultures on infectious complications following transrectal prostate biopsy.","authors":"Naveen Kumar Gupta, Kamalakanta Beheruk, Debansu Sarkar","doi":"10.1177/03915603251371657","DOIUrl":"https://doi.org/10.1177/03915603251371657","url":null,"abstract":"<p><strong>Introduction: </strong>To study the impact of rectal swab culture based targeted antimicrobial prophylaxis on infectious complications in patients undergoing transrectal ultrasound guided prostate biopsy.</p><p><strong>Methods: </strong>A prospective observational study was conducted in a tertiary care hospital at Kolkata, we compared the incidence of infectious complications in men who received rectal swab cultured based targeted prophylaxis versus empirical antibiotics prophylaxis who underwent transrectal ultrasound guided prostate biopsy. The targeted prophylactic antibiotics were selected from rectal culture swab plated on selected media containing ciprofloxacin to identify fluoroquinolone resistance, patients with infectious complications within 30 days of prostate biopsy were taken into consideration.</p><p><strong>Results: </strong>Twenty-four out of the 50 patients (48%) harbored FQ resistant organisms. Only three patients (6%) in the targeted prophylaxis group had infectious complications of UTI and Low-grade fever. In contrast, 6 (12%) of the 50 men undergoing the procedure without culture had infectious complications, two of these (4%) had sepsis.</p><p><strong>Conclusion: </strong>Frequently used fluoroquinolone prophylaxis fails to give adequate cover because of high rate of fluoroquinolone resistance of the rectal organism. Rectal swab derived antibiotics prophylaxis can reduce post biopsy infectious complications significantly.</p>","PeriodicalId":23574,"journal":{"name":"Urologia Journal","volume":" ","pages":"3915603251371657"},"PeriodicalIF":0.7,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145253001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Urologia JournalPub Date : 2025-10-08DOI: 10.1177/03915603251374888
Josué Daniel Segura-Arias, Carlos David Gómez-Carmona, Braulio Sánchez-Ureña, José Alexis Ugalde-Ramírez, Daniel Rojas-Valverde
{"title":"Interrelation between cycling and renal and urological health: A bibliometric and systematic review.","authors":"Josué Daniel Segura-Arias, Carlos David Gómez-Carmona, Braulio Sánchez-Ureña, José Alexis Ugalde-Ramírez, Daniel Rojas-Valverde","doi":"10.1177/03915603251374888","DOIUrl":"https://doi.org/10.1177/03915603251374888","url":null,"abstract":"<p><p>This systematic and bibliometric review synthesizes current knowledge of the relationship between cycling, renal and urological health. A comprehensive search of databases from 2000 to 2023 yielded 38 relevant studies. Bibliometric analysis revealed research trends, key institutions, authors, and countries that contributed to this field. This review discusses the benefits and risks associated with cycling. Benefits included improved cardiovascular health and metabolic function. However, cycling was also associated with urological symptoms, particularly in women, and with risks of erectile dysfunction and genital numbness in both genders. Mountain biking demonstrated higher rates of scrotal pathologies. Saddle design, riding position, and cycling intensity significantly influenced perineal pressure and potential urological issues. Renal biomarkers indicated dehydration, muscle damage, and potential renal insufficiencies in cyclists, especially after prolonged and intense activity. Elevated inflammatory markers and reduced glomerular filtration rates were observed post-cycling. Sodium intake and L-tryptophan supplementation demonstrated positive effects on fatigue reduction and recovery. The review identified research gaps, including limited long-term studies and inconsistent methodologies. Future research should focus on the relationship between high-volume cycling and prostate cancer risk, optimizing bicycle design to reduce urological issues, and developing reliable methods to measure saddle pressure effects on renal health. This review provided valuable insights for cyclists, health professionals, and researchers, emphasizing the need for awareness of potential health impacts and the importance of proper equipment and techniques to minimize risks while maximizing cycling benefits.</p>","PeriodicalId":23574,"journal":{"name":"Urologia Journal","volume":" ","pages":"3915603251374888"},"PeriodicalIF":0.7,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145253091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Urologia JournalPub Date : 2025-10-04DOI: 10.1177/03915603251378595
Mohammad Mehdi Hosseini, Alireza Sanati, Ali Eslahi, Dariush Irani, Abdolreza Haghpanah, Omid Khoshnood, Zeinab Karimi, Fatemeh Masjedi
{"title":"Comparison of subcostal and supracostal access in percutaneous nephrolithotomy of isolated upper pole stone: A prospective randomized clinical trial.","authors":"Mohammad Mehdi Hosseini, Alireza Sanati, Ali Eslahi, Dariush Irani, Abdolreza Haghpanah, Omid Khoshnood, Zeinab Karimi, Fatemeh Masjedi","doi":"10.1177/03915603251378595","DOIUrl":"https://doi.org/10.1177/03915603251378595","url":null,"abstract":"<p><strong>Purpose: </strong>To assess and compare the safety and efficacy of supracostal and subcostal access percutaneous nephrolithotomy (PCNL) for isolated upper pole stones, we designed a prospective randomized clinical trial.</p><p><strong>Materials and methods: </strong>A prospective randomized study of 76 patients (18-65 years old) was conducted from January 2024 to September 2024 on isolated upper calyceal renal stones at a medical teaching hospital. The eligible participants were divided into subcostal and supracostal access for PCNL groups (38 patients per group). The measured variables included age, sex, body mass index, stone size, comorbidities, procedure time, stone-free rate, hospital stay, and complications (modified Clavien Dindo grading).</p><p><strong>Results: </strong>Of 76 patients, 47 were male and 29 female, with a mean age of 47 and 53 years for the subcostal and supracostal groups, respectively. The mean stone size was 27.38 and 28.89 mm in the two studied groups, respectively. The mean operation and fluoroscopy time, hospital stay, laboratory data, and complications had no significant difference between the two investigated groups.</p><p><strong>Conclusion: </strong>Unlike the traditional view, supracostal access during PCNL is safe and effective and is not associated with a higher incidence of postoperative complications. However, both procedures were performed by skilled surgeons, so surgeons should have sufficient training and choose the proper method for each patient individually to minimize complications and obtain the best results. Further studies with a large number of cases are recommended.</p>","PeriodicalId":23574,"journal":{"name":"Urologia Journal","volume":" ","pages":"3915603251378595"},"PeriodicalIF":0.7,"publicationDate":"2025-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145226250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Urologia JournalPub Date : 2025-09-28DOI: 10.1177/03915603251376393
Soumya Ranjan Behera, Samir Swain, Mamata Jena, Zaid Ahmad Khan, Arijit Saha, Sabyasachi Panda, Pramod Kumar Mohanty, Jesse James Rani, Shashank Shekhar Prasad Mohapatra
{"title":"Role of NNMT and NM23A for diagnosis of RCC: Renal Cell Carcinoma.","authors":"Soumya Ranjan Behera, Samir Swain, Mamata Jena, Zaid Ahmad Khan, Arijit Saha, Sabyasachi Panda, Pramod Kumar Mohanty, Jesse James Rani, Shashank Shekhar Prasad Mohapatra","doi":"10.1177/03915603251376393","DOIUrl":"https://doi.org/10.1177/03915603251376393","url":null,"abstract":"<p><strong>Objective: </strong>This study investigates the diagnostic potential of nicotinamide N-methyltransferase (NNMT) and NM23A as biomarkers for renal cell carcinoma (RCC), focusing on their ability to facilitate early detection and improve diagnostic precision.</p><p><strong>Methods: </strong>A prospective observational study was conducted over 24 months, enrolling patients with RCC, benign renal tumors, and healthy controls. Biomarker levels were measured using enzyme-linked immunosorbent assays (ELISA). Diagnostic performance was evaluated through statistical analyses, including ROC curve analysis and Mann-Whitney U tests. Additionally, machine learning models such as Random Forest and Gradient Boosting were employed to identify key predictors of RCC.</p><p><strong>Results: </strong>NNMT and NM23A demonstrated significant diagnostic accuracy, with area under the curve (AUC) values of 0.933 and 0.915, respectively. Both biomarkers showed substantial differences across RCC, benign, and control groups (<i>p</i> < 0.001). Machine learning analyses highlighted NNMT as the most influential predictor for RCC diagnosis, further supporting its clinical relevance.</p><p><strong>Conclusions: </strong>NNMT and NM23A emerge as promising non-invasive biomarkers for RCC, offering substantial diagnostic accuracy and reducing reliance on invasive procedures. Their integration into clinical workflows, supported by advanced machine learning methodologies, could transform RCC diagnostics. Further research with diverse populations is recommended to validate these findings and expand their clinical applicability.</p>","PeriodicalId":23574,"journal":{"name":"Urologia Journal","volume":" ","pages":"3915603251376393"},"PeriodicalIF":0.7,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145182187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Urologia JournalPub Date : 2025-09-28DOI: 10.1177/03915603251381394
Akif Erbin
{"title":"Optimal approach to residual upper pole stones after PCNL: Re-evaluating the role of RIRS with current technological developments.","authors":"Akif Erbin","doi":"10.1177/03915603251381394","DOIUrl":"https://doi.org/10.1177/03915603251381394","url":null,"abstract":"","PeriodicalId":23574,"journal":{"name":"Urologia Journal","volume":" ","pages":"3915603251381394"},"PeriodicalIF":0.7,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145182277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Urologia JournalPub Date : 2025-09-20DOI: 10.1177/03915603251380040
Rodolfo Montironi, Alessia Cimadamore, Antonio Lopez-Beltran, Liang Cheng
{"title":"Re: Urology in the digital age: The power of telemedicine, Urologia. 2025 Jul 16:3915603251356555. Past, present, and future roles for uropathologists in telemedicine.","authors":"Rodolfo Montironi, Alessia Cimadamore, Antonio Lopez-Beltran, Liang Cheng","doi":"10.1177/03915603251380040","DOIUrl":"https://doi.org/10.1177/03915603251380040","url":null,"abstract":"","PeriodicalId":23574,"journal":{"name":"Urologia Journal","volume":" ","pages":"3915603251380040"},"PeriodicalIF":0.7,"publicationDate":"2025-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145092553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Urologia JournalPub Date : 2025-09-20DOI: 10.1177/03915603251378596
Rathindra Nath Ray, Anshu Kumar, Ruchita Agarwal, G S Kamilya, Taquedis Noori, Monika Shah
{"title":"Combination treatment of mirabegron and solifenacin versus solifenacin monotherapy in female patients with overactive bladder - A comparative study on effectiveness, safety, symptoms and quality of life and treatment adherence.","authors":"Rathindra Nath Ray, Anshu Kumar, Ruchita Agarwal, G S Kamilya, Taquedis Noori, Monika Shah","doi":"10.1177/03915603251378596","DOIUrl":"https://doi.org/10.1177/03915603251378596","url":null,"abstract":"<p><strong>Purpose: </strong>Compared to other overactive bladder (OAB) symptoms, incontinence has a more negative impact on quality of life and is frequently challenging to treat with antimuscarinic monotherapy. This study's goal was to compare the safety, tolerability, and effectiveness of a combination of solifenacin 5 mg and mirabegron 25 mg or 50 mg versus solifenacin 5 mg in patients with OAB.</p><p><strong>Material and methods: </strong>In a tertiary care hospital, 258 individuals with overactive bladders participated in a randomised controlled open-label research to examine the safety and efficacy of mirabegron as a supplement to solifenacin. Randomisation was used to assign patients to one of three groups: those receiving solifenacin (5 mg) with mirabegron (25 mg), solifenacin (5 mg) plus mirabegron (50 mg) or solifenacin (5 mg) monotherapy. OABSS was used to examine the patients. A change in the OABSS from baseline to end of treatment (EOT) was the main outcome measure. This research also examined the safety and tolerability of combination treatment in comparison to solifenacin monotherapy.</p><p><strong>Results: </strong>All combinations with solifenacin five substantially improved the OAB symptoms score as compared to solifenacin 5 mg monotherapy. When compared to solifenacin 5 mg, both combination groups significantly decreased the frequency of micturition. Although there were no dose-related differences between the combination and monotherapy groups in terms of TEAEs, blood pressure, pulse rate, PVR volume, or laboratory or ECG parameters, combination medication did result in a slightly higher frequency of constipation.</p><p><strong>Conclusions: </strong>When compared to solifenacin 5 mg monotherapy, combination therapy with solifenacin/mirabegron markedly improved OABSS, micturition frequency, and urgency. When compared to monotherapy, all combinations were well tolerated and showed no significant extra safety concerns.</p>","PeriodicalId":23574,"journal":{"name":"Urologia Journal","volume":" ","pages":"3915603251378596"},"PeriodicalIF":0.7,"publicationDate":"2025-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145092512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mapping the landscape of uro-oncology research: A scientometric analysis of systematic reviews and meta-analyses (2020-2025).","authors":"Hazhir Ahmadi Shilanabad, Nima Naghdi Sedeh, Helia Mostafaei, Mohsen Mohammadrahimi, Hanieh Salehi-Pourmehr, Sakineh Hajebrahimi","doi":"10.1177/03915603251374375","DOIUrl":"https://doi.org/10.1177/03915603251374375","url":null,"abstract":"<p><strong>Background: </strong>Uro-oncology, a multidisciplinary field at the intersection of urology and oncology, holds a pivotal role in the diagnosis, treatment, and prevention of genitourinary cancers. Quantitative and qualitative evaluation of scientific publications, particularly review articles, in the field of uro-oncology provides comprehensive insights into the research landscape. This study provides a scientometric and bibliographic analysis of systematic reviews and meta-analyses in this field based on publications indexed in Scopus between 2020 and 2025.</p><p><strong>Methods: </strong>Employing a descriptive-analytical design, we analyzed publication trends, citation patterns, core journals, key authors, and collaboration networks using bibliometric tools like R (Bibliometrix, Biblioshiny) and VOSviewer.</p><p><strong>Results: </strong>Our findings reveal a notable decline in the annual growth rate of publications (-63.18%) and a significant reduction in average citations per article. While core journals such as <i>Cancers</i>, <i>Frontiers in Oncology</i>, and <i>International Journal of Molecular Sciences</i> dominate the field, inconsistencies in Scopus metadata, particularly missing citation counts and science categories, limit the accuracy of bibliometric analysis. Despite these challenges, key researchers and consistent focus on areas like immunotherapy and biomarker development are evident.</p><p><strong>Conclusion: </strong>The study highlights the need for better data curation, targeted funding, and stronger international collaboration to revitalize uro-oncology research.</p>","PeriodicalId":23574,"journal":{"name":"Urologia Journal","volume":" ","pages":"3915603251374375"},"PeriodicalIF":0.7,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145087500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of physiotherapy interventions in urinary incontinence and on overall quality of life in patients undergoing treatment for prostate cancer: A systematic review.","authors":"Puspangi Agarwal, Aksh Chahal, Nidhi Sharma, Richa Hirendra Rai, Yulduz Urazbaeva, Mukhayya Djumaniyazova, Abhishek Sharma","doi":"10.1177/03915603251372244","DOIUrl":"https://doi.org/10.1177/03915603251372244","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this systematic review is to extract inference from research articles published through evidence-based practice physiotherapy toward resistance training, aerobic exercises, trunk specific exercises, pelvic floor muscle training and manual therapy in managing urinary incontinence and sexual dysfunction along with strategies implemented to improve quality of life in patients undergoing treatment for prostate cancer.</p><p><strong>Methods: </strong>The databases PubMed, Google Scholar, PEDro, MEDLINE, and Cochrane were systematically searched for this review. Two authors independently evaluated the methodological quality of the included studies using the PEDro scale to ensure reliability and validity.</p><p><strong>Results: </strong>Total of 22 studies, comprising 1589 participants with a mean age of 62.16 ± 7.24 years were included in the review after meeting the inclusion and exclusion criteria. Physiotherapy interventions, including resistance training, aerobic exercises, trunk-specific exercises, pelvic floor muscle training, and manual therapy, demonstrated significant improvements in managing urinary incontinence among patients undergoing prostate cancer treatment. Pelvic floor muscle training was particularly effective in reducing incontinence, while resistance and aerobic training contributed to enhanced physical function and quality of life. Data extraction and verification were performed independently by two authors, with three authors cross-referencing for additional articles.</p><p><strong>Conclusion: </strong>The clinical presentation in patients undergoing treatment for prostate cancer was found to be positively influenced by physiotherapy interventions, decreasing the symptoms of urinary incontinence and thus, improving the quality of life.</p>","PeriodicalId":23574,"journal":{"name":"Urologia Journal","volume":" ","pages":"3915603251372244"},"PeriodicalIF":0.7,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145076003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Urologia JournalPub Date : 2025-09-12DOI: 10.1177/03915603251378593
Jorge Panach-Navarrete, José María Martínez-Jabaloyas
{"title":"Response to \"Use of the Allium stent for management of ureteral pathology: A real-world clinical practice study\".","authors":"Jorge Panach-Navarrete, José María Martínez-Jabaloyas","doi":"10.1177/03915603251378593","DOIUrl":"https://doi.org/10.1177/03915603251378593","url":null,"abstract":"","PeriodicalId":23574,"journal":{"name":"Urologia Journal","volume":" ","pages":"3915603251378593"},"PeriodicalIF":0.7,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}