Urologia Journal最新文献

{"title":"Efficacy and safety of lithotripsy with ureteroscopy for ureteral stones in octogenarians.","authors":"Ryo Sato, Asuka Uchiyama, Shungo Kakinuma, Rikiya Matsumoto","doi":"10.1177/03915603251343168","DOIUrl":"https://doi.org/10.1177/03915603251343168","url":null,"abstract":"<p><strong>Objective: </strong>To assess the efficacy and safety of lithotripsy with ureteroscopy for managing ureteral stone in octogenarian patients.</p><p><strong>Materials and methods: </strong>This retrospective study analyzed 314 patients who underwent retrograde lithotripsy with ureteroscopy for ureteral stones between January 2018 and August 2024. Patients were categorized into two groups based on age: the octogenarian group (⩾80 years) and the younger patient group (<80 years). Clinical parameters, including the stone-free rate, postoperative length of hospital stay, and postoperative complications, were compared. To minimize confounding variables, 1:1 propensity score matching was performed, resulting in 41 patients in each group.</p><p><strong>Results: </strong>After propensity score matching, no significant differences in baseline clinical characteristics between the groups. Additionally, no statistically significant differences were observed in the stone-free rate, postoperative length of hospital stay, or postoperative complication rates between the two cohorts.</p><p><strong>Conclusion: </strong>These findings suggest that lithotripsy with ureteroscopy is an effective and safe treatment option for ureteral stones in carefully selected octogenarian patients.</p>","PeriodicalId":23574,"journal":{"name":"Urologia Journal","volume":" ","pages":"3915603251343168"},"PeriodicalIF":0.8,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144128482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of CPB in surgery for extended tumor thrombosis of inferior vena cava and right atrium.","authors":"Mingchen Shao, Roman N Komarov, Leonid M Rapoport, Dmitry O Korolev, Ilya Vasalatii","doi":"10.1177/03915603251338717","DOIUrl":"https://doi.org/10.1177/03915603251338717","url":null,"abstract":"<p><strong>Objective: </strong>To research the best time to provide cardiopulmonary bypass (CPB) and the best way to do it when treating an extensive tumor thrombosis of the inferior vena cava vein (IVC).</p><p><strong>Results: </strong>The operating times in groups A and B were (376.7 ± 91.2) and (373.1 ± 80.7) minutes, respectively, with no statistically significant difference (<i>t</i> = 0.716, <i>p</i> > 0.05); intraoperative bleeding was (1916.7 ± 925.1) ml and (2600 ± 3756.3) ml, (<i>t</i> = -0.601, <i>p</i> < 0.05), and hospitalization was (32.3 ± 16.0) and (34.0 ± 8.0) days, with statistically significant differences (<i>p</i> < 0.05).</p><p><strong>Conclusion: </strong>The CPB approach has the advantages of less intraoperative blood loss, faster surgical procedures, and fewer hospitalizations.</p>","PeriodicalId":23574,"journal":{"name":"Urologia Journal","volume":" ","pages":"3915603251338717"},"PeriodicalIF":0.8,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144086755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation analysis of age, abstinence, and seasons with semen parameters in untreated male partners of infertile couples.","authors":"Natali Ilaria, Millanti Lorenzo, Siondino Sergio, Peluso Giuseppina, Errichiello Luigi","doi":"10.1177/03915603251334077","DOIUrl":"https://doi.org/10.1177/03915603251334077","url":null,"abstract":"<p><p>Many studies reveal the presence of an effect of age, abstinence and seasons on semen parameters, but the number of patients enrolled is small and the presence of therapies unknown. We aimed to evaluate the correlation between abstinence days, age, season, and semen parameters (volume, concentration, progressive motility, total number of sperms, morphology) among men referred to our laboratory. We proceeded with a cross-sectional, observational, exploratory study in an Andrology laboratory. A population of 348 male partners of infertile couples who did not receive any treatment in the 3 months preceding semen analysis was selected. Sperm volume, concentration, total number, progressive motility and morphology of sperms were conducted strictly following the guidelines indicated in the last edition of WHO manual for semen analysis. Pearson's correlation analysis and Kendall's correlation analysis were applied. Sperm concentration, semen volume and sperm total number moderately increased as well as the abstinence, while progressive motility and morphology moderately decreased. Regarding the age, in the 20-35 age group there was a weak inverse association with concentration, total number, motility and morphology and a weak positive association with volume; in the 42-63 age group there was a moderate positive association between age and concentration, motility and morphology, but an inverse association with volume. No correlation emerged between seasonal variations and semen parameters. These results suggested the importance of correct information to patients for proper semen analysis for diagnostic and therapeutic purposes.</p>","PeriodicalId":23574,"journal":{"name":"Urologia Journal","volume":" ","pages":"3915603251334077"},"PeriodicalIF":0.8,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144086763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical spectrum and management of Fournier's gangrene among diabetics and non-diabetics: A comparative study.","authors":"Ashish Ranjan, Samrat Biswas, Nidhi Bhatnagar, Debabrata Kundu","doi":"10.1177/03915603251338715","DOIUrl":"https://doi.org/10.1177/03915603251338715","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to assess the clinical outcomes of Fournier's gangrene and its predisposing factors in male diabetic and non-diabetic patients. We also evaluated the disease severity using the Fournier's Gangrene Severity Index and examined management outcomes, including mode of wound closure and complications related to the disease and treatment.</p><p><strong>Methods: </strong>Patients with Fournier's gangrene underwent admission, with detailed history collection. Disease severity was clinically and laboratory assessed. Empirical antibiotics preceded surgical management and microbial evaluation. Wound closure involved primary suturing, skin grafting, or flaps. Patients were called for regular follow-up after discharge, and complications were identified.</p><p><strong>Results: </strong>Our study has shown that the overall FGSI was much higher among diabetics as compared to non-diabetics, and the same goes for the mortality rate, which was much higher in diabetics, owing to the higher rate of complications among them. It was also found that the prognosis of Fournier's gangrene is worse among diabetics. The mean number of debridement's in the diabetic group (3.00 ± 1.016) was higher than the non-diabetic group (2.22 ± 1.003). The association between number of debridement's in the two groups was statistically significant (<i>p</i> = 0.001).</p><p><strong>Conclusion: </strong>Early diagnosis and aggressive management are crucial to reduce Fournier's gangrene mortality. Effective diabetic control and repeated debridement are necessary to successfully manage these complex cases.</p>","PeriodicalId":23574,"journal":{"name":"Urologia Journal","volume":" ","pages":"3915603251338715"},"PeriodicalIF":0.8,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144086760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prediction of operation time in percutaneous nephrolithotomy (PCNL) patients: A machine learning approach.","authors":"Owais Ghammaz, Rami Alazab, Nabil Ardah, Mohammed Jalal Akel, Bashar Tayyem, Nazih Alhirtani, Abdallah Bakeer, Bader Al-Deen Anabtawi, Eyas Amaierh, Azhar Al-Alwani","doi":"10.1177/03915603251338720","DOIUrl":"https://doi.org/10.1177/03915603251338720","url":null,"abstract":"<p><strong>Purpose: </strong>To investigate the factors influencing the length of percutaneous nephrolithotomy (PCNL) procedures and identify predictive variables for operation time using machine learning models.</p><p><strong>Materials and methods: </strong>A retrospective, observational cohort study was conducted at King Abdullah University Hospital, including 352 patients who underwent PCNL between January 2017 and September 2023. Data on preoperative and postoperative variables were collected from electronic health records. Four machine learning algorithms (Random Forest Classifier, AdaBoost Classifier, eXtreme Gradient Boosting Classifier, Logistic Regression) were employed to predict operation time, with features standardized using the StandardScaler module and Synthetic Minority Over-sampling Technique (SMOTE) used to address data imbalance. The dataset was split into training (80%) and testing (20%) sets. Model performance was evaluated using ROC curves, AUC scores, accuracy, precision, recall, and F1-score.</p><p><strong>Results: </strong>Stone burden, gender, and hydronephrosis were significantly associated with longer operation times. Machine learning analysis identified stone-free status, stone burden, and gender as key predictors, with the eXtreme Gradient Boosting Classifier achieving the highest AUC (0.789). Patients with non-stone-free status had longer operation times (<i>p</i> < 0.001). Stone burden and specific stone locations also significantly impacted procedure duration.</p><p><strong>Conclusion: </strong>Stone-free status followed by stone burden and gender are critical predictors of PCNL operation time. Achieving stone-free status significantly reduces procedure duration. Machine learning models, particularly eXtreme Gradient Boosting, provide valuable predictive insights, aiding in surgical planning and optimizing patient outcomes.</p>","PeriodicalId":23574,"journal":{"name":"Urologia Journal","volume":" ","pages":"3915603251338720"},"PeriodicalIF":0.8,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144086708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Zinner syndrome: Clinical insights from Western Norway.","authors":"Emanuel Bjurulf, Lars A R Reisæter, Hemamaalini Rajkumar, Adeel Asghar Chaudhury, Alfred Honoré, Florin Hopland-Nechita, Christian Arvei Moen, Julie Nøss Haugland, Ravi Rawal, Ingunn Roth, Anh Khoi Vo, Christian Beisland, Patrick Juliebø-Jones","doi":"10.1177/03915603251335609","DOIUrl":"https://doi.org/10.1177/03915603251335609","url":null,"abstract":"<p><strong>Introduction: </strong>Zinner syndrome (ZS) is characterised by unilateral renal agenesis, ipsilateral seminal vesicle cyst and obstruction of the ejaculatory duct. Although rare, urologists may encounter it at some point in their clinical practice. The literature is largely limited to case reports, and the condition is poorly understood. Our objective was to report on cases of ZS that have been managed at two centres in order to gain further clinical insights on this condition.</p><p><strong>Methods: </strong>A retrospective review was conducted on ZS cases presenting at two centres in Western Norway between January 2021 and June 2024. Data were collected on demographic details, symptomatology, imaging findings, management and fertility outcomes.</p><p><strong>Results: </strong>Six cases were identified that met the full triad for ZS, with ages ranging from 18 to 70 years. Five patients were symptomatic at presentation, reporting issues such as anejaculation and testicular pain during sexual activity. Two cases presented as emergencies, one with acute urinary retention and the other with severe pelvic pain. Half of the patients were successfully managed with a conservative approach. Two-thirds had children, either through natural conception or assisted reproductive methods, while the remaining patients underwent sperm cryopreservation.</p><p><strong>Conclusion: </strong>ZS presents with a wide range of symptoms and at varying ages. Not all symptomatic cases require surgical intervention, and management should be individualised. In select cases, a conservative approach can feasible.</p>","PeriodicalId":23574,"journal":{"name":"Urologia Journal","volume":" ","pages":"3915603251335609"},"PeriodicalIF":0.8,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144001053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between thyroid disorders and the Risk of developing prostate cancer: A systematic review and meta-analysis.","authors":"Daniel Andrés Nieva-Posso, Valeria Perea Ocampo, Daniel Alfonso Nieva Posso, Herney Andrés García-Perdomo","doi":"10.1177/03915603251336971","DOIUrl":"https://doi.org/10.1177/03915603251336971","url":null,"abstract":"<p><strong>Objective: </strong>To determine the association between thyroid disorders and the Risk of developing prostate cancer.</p><p><strong>Methods: </strong>We conducted this review following the recommendations of the Cochrane Collaboration and the PRISMA Statement. From the moment to the present, we have conducted a search strategy using MEDLINE, WEB OF SCIENCE, and GOOGLE SCHOLAR. We included cohort and case-control studies that examined the relationship between thyroid disorders and the Risk of developing prostate cancer. We assessed the Risk of bias using the Newcastle Ottawa Quality Assessment scale. Meta-analysis was conducted in Review Manager 5.4.1 (Revman^®).</p><p><strong>Results: </strong>We included nine studies in the analysis. The studies included were classified into two groups: those that studied hypothyroidism and those that studied hyperthyroidism. The results showed no association between thyroid abnormalities and prostate cancer risk, with an HR of 1.05 (95% CI: 0.90-1.22). Hyperthyroidism also showed no association with an HR 1.64 (95% CI: 1.00-2.69), characterized by increased serum T4 and decreased TSH. There was also no significant association with hypothyroidism, with an HR of 0.85 (95% CI: 0.67-1.10).</p><p><strong>Conclusion: </strong>Thyroid disorders were not associated with the Risk of developing prostate cancer.</p>","PeriodicalId":23574,"journal":{"name":"Urologia Journal","volume":" ","pages":"3915603251336971"},"PeriodicalIF":0.8,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144016076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biparametric magnetic resonance imaging as a diagnostic tool for differentiating RCC and renal pseudotumor in CKD patients.","authors":"Himanshu Raj, Hira Lal, Sanchit Rustagi, Arpan Yadav, Uday Pratap Singh, Anil Baid, Sanjoy Kumar Sureka","doi":"10.1177/03915603241276738","DOIUrl":"10.1177/03915603241276738","url":null,"abstract":"<p><strong>Introduction: </strong>Pseudotumors are benign lesions which may mimic like a malignant tumor on conventional imaging. They are formed in kidneys which are scarred and deformed by chronic pyelonephritis, glomerulonephritis, trauma or infarction. There is a diagnostic dilemma in most of the cases as to differentiate RCC and pseudotumors. Our study shows bp-MRI (T2w, DW MRI) can distinguish pseudotumors from RCCs and offers a non-contrast non-invasive alternative in CKD patients.</p><p><strong>Materials and methods: </strong>Prospective evaluation of 80 CKD patients (CKD IV/V), having suspicious renal mass <4 cm on Ultrasound, were subjected to bp-MRI. Two groups were defined on the basis of restriction pattern on DWI. ADC values were calculated. Group I (suspected RCC or malignant tumor) underwent surgical management according to the institutional protocol. Group II (suspected pseudotumor) were subjected to biopsy. ROC curves were drawn to find out area under curve for differentiation of groups and cut-off ADC values calculated so as to achieve highest average sensitivity and specificity. A <i>p</i>-value of <0.05 was considered as statistically significant.</p><p><strong>Results: </strong>Sixty patients (Group I) had restricted pattern on DWI imaging whilst 20 had no restriction (Group II), hence ruling out malignancy. It showed a sensitivity of 81.82%, specificity 96.55% in the correct diagnosis. Mean ADC-value for CKD pseudotumors (Group II) was significantly higher than RCCs and surrounding diseased parenchyma (2.20 vs 1.52 (×10^-3 mm²/s; <i>p</i> < 0.0001) and 1.99 (×10^-3 mm²/s; <i>p</i> = 0.0001) respectively). ROC analysis for differentiating CKD pseudotumors and RCC yielded high sensitivity (85%) and specificity (99%) for cut-off ADC-value of 1.71 (×10^-3 mm²/s).</p><p><strong>Conclusion: </strong>bp-MRI is a highly reliable imaging modality for the evaluation of renal lesions. Its ability to accurately differentiate pseudotumors from renal cell carcinomas, even in the absence of contrast administration can be a boon in the diagnostic armamentarium.</p>","PeriodicalId":23574,"journal":{"name":"Urologia Journal","volume":" ","pages":"201-208"},"PeriodicalIF":0.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between post-prostatectomy urinary incontinence, sexual functions, and dyadic adjustment: A cross-sectional study.","authors":"Francesco Rossi, Filippo Marino, Carlo Gandi, Francesco Pio Bizzarri, Marco Campetella, Riccardo Bientinesi, Marco Silvaggi, Emilio Sacco","doi":"10.1177/03915603241299856","DOIUrl":"10.1177/03915603241299856","url":null,"abstract":"<p><strong>Introduction: </strong>Robot-assisted radical prostatectomy (RARP) is the treatment option for localized prostate cancer. It can lead to side effects like erectile dysfunction (ED) and post-prostatectomy urinary incontinence (PPUI). This study aimed to evaluate association between dyadic adjustment, PPUI and ED.</p><p><strong>Material and methods: </strong>Consecutive male patients who underwent RARP from January 2019 to December 2021, with at least 12 months of follow-up and preoperative International Index of Erectile Function (IIEF) 15 erectile domain questionnaire's score ⩾17 were enrolled. Demographic and surgical data were collected at baseline. Validated questionnaires were self-administered at 12-month follow-up: IIEF-15, Dyadic Adjustment scale (DAS), and Los Angeles-Prostate Cancer Index Urinary Function Score (UCLA-PCI-UFS). Univariable and multivariable analyses were performed to examine degree of association between different variables.</p><p><strong>Results: </strong>Out of 96 enrolled patients, 37 (38.5%) were socially incontinent (>1 pad per day) at 12 months from surgery. Statistically significant association was found between incontinence and lower DAS total score (<i>p</i> < 0.0001), DAS consensus domain (<i>p</i> < 0.0001), and DAS affectional expression domain (<i>p</i> = 0.002). DAS total score (<i>p</i> = 0.002) and DAS consensus domain score (<i>p</i> = 0.012) were lower in impotent group (IIEF-15 erectile domain score <17). On a multivariable analysis, PPUI (beta: -0.25; 95% CI: -4.42, -0.47; <i>p</i> = 0.016) and post-operative ED (beta: 0.19; 95% CI: 0.002, 0.57; <i>p</i> = 0.048) were independent predictors of low DAS score. Pelvic lymphadenectomy (PLND) (beta coefficient: 0.25; 95% CI: 0.1, 1.2; <i>p</i> = 0.022), bladder neck reconstruction (beta: 0.26; 95% CI: 0.19, 1.09; <i>p</i> = 0.006), and ED (beta coefficient: -0.3; 95% CI: -0.07, -0.018; <i>p</i> = 0.001) were independent predictors of continence status.</p><p><strong>Conclusion: </strong>PPUI following RARP is associated with lower dyadic adjustment, independently from other factors, indicating significant impact of PPUI on marital relationships. Further research should be conducted to understand better the cross-effective relationship between PPUI, potency, dyadic adjustment, and the effect of surgical treatments on incontinence and sexual function.</p>","PeriodicalId":23574,"journal":{"name":"Urologia Journal","volume":" ","pages":"348-354"},"PeriodicalIF":0.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142886112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of androgen deprivation therapy after radical prostatectomy on urinary symptoms.","authors":"Shohei Kawaguchi, Kazuyoshi Shigehara, Yoshifumi Kadono, Yuki Kato, Hiroshi Kano, Tomoyuki Makino, Renato Naito, Hiroaki Iwamoto, Hiroshi Yaegashi, Takahiro Nohara, Kouji Izumi, Atsushi Mizokami","doi":"10.1177/03915603241310090","DOIUrl":"10.1177/03915603241310090","url":null,"abstract":"<p><strong>Introduction: </strong>Salvage intermittent ADT has been demonstrated to be a potentially effective treatment option for BCR following RP. Although ADT improves urinary symptoms by reducing prostate volume, no studies have been conducted to investigate its effect on urinary symptoms after RP. We retrospectively examined changes in urinary symptoms in patients who developed BCR after RP and underwent salvage intermittent ADT.</p><p><strong>Methods: </strong>OABSS, IPSS, and ICIQ-SF scores were compared before ADT, 3 months after the start of ADT, 12 months after the start of ADT, at the end of ADT, and 1 year after the end of ADT in patients who received intermittent ADT following RARP. In addition, changes in urinary symptoms were compared between the group with pre-ADT testosterone levels <400 ng/dL (low testosterone group) and the group with levels ⩾400 ng/dL (high testosterone group).</p><p><strong>Results: </strong>Three months after the initiation of ADT, the IPSS total score, IPSS urine storage score, and ICIQ-SF score were significantly higher compared to their pre-treatment levels. In the low testosterone group, the ICIQ-SF score was significantly worse only at 12 months after the start of ADT compared to before the start of ADT. In the high testosterone group, the IPSS total score, storage IPSS score, and ICIQ-SF score were significantly higher at both 3 and 12 months after initiating ADT compared to their pre-treatment levels.</p><p><strong>Conclusions: </strong>ADT for BCR after RARP has been shown to significantly worsen urinary storage symptoms while not improving voiding symptoms, particularly in patients with high testosterone levels pre-ADT.</p>","PeriodicalId":23574,"journal":{"name":"Urologia Journal","volume":"92 2","pages":"329-334"},"PeriodicalIF":0.8,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143765184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}