Veterinary Record最新文献_第3页

Randomised, blinded clinical trial comparing dogs' sedation scores following methadone-medetomidine injection at Governing Vessel 20, the epaxial lumbar muscles or the quadriceps muscles. 随机、盲法临床试验比较美沙酮-美托咪定注射支配血管20、轴外腰肌或股四头肌后狗的镇静评分。

IF 0.9 3区农林科学

Veterinary Record Pub Date : 2026-09-28 DOI: 10.1002/vetr.71213

Hillen Florence, Yates David, White Kate

{"title":"Randomised, blinded clinical trial comparing dogs' sedation scores following methadone-medetomidine injection at Governing Vessel 20, the epaxial lumbar muscles or the quadriceps muscles.","authors":"Hillen Florence, Yates David, White Kate","doi":"10.1002/vetr.71213","DOIUrl":"https://doi.org/10.1002/vetr.71213","url":null,"abstract":"Background: Intramuscular injection of sedatives into different muscles may affect the quality of sedation. Subcutaneous injection is less painful but has a less predictable effect; however, administration at Governing Vessel 20 (GV20) may improve sedation.Methods: Seventy-three dogs were premedicated with medetomidine and methadone. The route of administration was determined by random allocation: subcutaneous injection at GV20 (GV-20), intramuscular injection into the quadriceps muscles (IM-Q) or intramuscular injection into the epaxial lumbar muscles (IM-L). Sedation was scored at 3, 7 and 10 minutes after injection using a simple descriptive scale.Results: Scores were higher in groups IM-Q and GV-20 than in group IM-L and did not differ significantly between GV-20 and IM-Q at any time point. Scores differed significantly between IM-L and IM-Q at 3 minutes, between IM-L and both IM-Q and GV-20 at 7 minutes, and between GV-20 and IM-L at 10 minutes.Limitations: Differences in patient size between groups, inter-rater variability and the use of allometric dosing may have affected the results.Conclusions: The quality of sedation following injection of methadone and medetomidine at GV20 does not differ significantly from that following injection into the quadriceps muscles, and the injection is well tolerated. Injection into the epaxial lumbar muscles results in less profound sedation, possibly because of inadvertent subcutaneous injection or anatomical differences in tissue perfusion.","PeriodicalId":23560,"journal":{"name":"Veterinary Record","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149075891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnosis of bovine genital leptospirosis in asymptomatic bulls: Comparison of methods and samples under field conditions. 无症状公牛中牛生殖器钩端螺旋体病的诊断：在野外条件下方法和样本的比较。

IF 0.9 3区农林科学

Veterinary Record Pub Date : 2026-09-27 DOI: 10.1002/vetr.71220

Juliana Pedrosa, Daiany Motta, Wilmara Gregg, André Rodrigues, Walter Lilenbaum

{"title":"Diagnosis of bovine genital leptospirosis in asymptomatic bulls: Comparison of methods and samples under field conditions.","authors":"Juliana Pedrosa, Daiany Motta, Wilmara Gregg, André Rodrigues, Walter Lilenbaum","doi":"10.1002/vetr.71220","DOIUrl":"https://doi.org/10.1002/vetr.71220","url":null,"abstract":"Background: Bovine leptospirosis is a zoonosis of global importance that is associated with reproductive losses. Although diagnosis in females has advanced, genital infection in males remains poorly understood. This cross-sectional study aimed to compare diagnostic methods and sample types for detecting bovine genital leptospirosis (BGL) in bulls under field conditions.Methods: Blood, urine, semen and preputial cytology samples were collected from 37 unvaccinated bulls and analysed by serology (microscopic agglutination test -MAT) and lipL32-PCR.Results: Serology showed low seroreactivity (13.5%), whereas PCR detected infection in 80.5% of bulls. Leptospira DNA was identified in semen (70.6%), preputial cytology samples (50%) and urine (46.8%). PCR detected a higher proportion of positive animals than MAT (p < 0.05). The genital tract had a higher frequency of Leptospira detection than the urinary tract (p < 0.05), with no significant difference between semen and preputial cytology samples (p > 0.05).Limitations: The sample size was small, and the number of samples collected differed among sample types.Conclusions: PCR using genital samples-semen and/or preputial cytology-is the method of choice for diagnosing BGL in asymptomatic bulls.","PeriodicalId":23560,"journal":{"name":"Veterinary Record","volume":" ","pages":"e71220"},"PeriodicalIF":0.9,"publicationDate":"2026-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149070199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Perioperative analgesia and postoperative motor function after saphenous and sciatic nerve blocks in goats undergoing bilateral stifle surgery: A pilot study. 双侧窒息手术山羊隐神经和坐骨神经阻滞后围手术期镇痛和术后运动功能：一项初步研究。

IF 0.9 3区农林科学

Veterinary Record Pub Date : 2026-09-27 DOI: 10.1002/vetr.71212

Xavier Torruella, Claire Loughran, Flavia Restitutti, Joei Potter, Margot C Labberté, Pieter A J Brama, Vilhelmiina Huuskonen

{"title":"Perioperative analgesia and postoperative motor function after saphenous and sciatic nerve blocks in goats undergoing bilateral stifle surgery: A pilot study.","authors":"Xavier Torruella, Claire Loughran, Flavia Restitutti, Joei Potter, Margot C Labberté, Pieter A J Brama, Vilhelmiina Huuskonen","doi":"10.1002/vetr.71212","DOIUrl":"https://doi.org/10.1002/vetr.71212","url":null,"abstract":"Background: The combination of femoral and sciatic nerve blocks offers adequate perioperative analgesia for goats undergoing stifle surgery. However, postoperatively, residual motor dysfunction may lead to distress and discomfort. This study evaluated whether combined saphenous and sciatic nerve blocks provide adequate perioperative analgesia without clinically relevant postoperative pelvic limb motor impairment.Methods: In this prospective, randomised, blinded study, 19 female goats undergoing bilateral stifle arthrotomy received bilateral ultrasound-guided saphenous and neurostimulator-guided sciatic nerve blocks. Group Bupivacaine/Lidocaine (BL) received 0.5% bupivacaine for the saphenous block and 2% lidocaine for the sciatic block; group Lidocaine/Lidocaine (LL) received 2% lidocaine for both blocks. Dexmedetomidine (0.25 µg/kg) was added per block. Ketamine was administered intraoperatively if pulse rate or mean arterial pressure increased by more than 20% from baseline.Results: Of nine goats, intraoperative ketamine was required in three goats in group BL and one goat in group LL. Two goats in each group showed proprioceptive deficits 30 minutes after extubation, but none did so at 60 minutes. No significant differences were detected for any measured variable.Limitations: This study was limited by small sample size, lack of a control group and use of a non-validated postoperative pain scale.Conclusion: Combined saphenous and sciatic nerve blocks provided clinically useful intraoperative and early postoperative analgesia as part of a multimodal analgesic protocol without clinically relevant motor blockade in goats undergoing bilateral stifle arthrotomy. Overall, no statistically significant differences were detected in this pilot study.","PeriodicalId":23560,"journal":{"name":"Veterinary Record","volume":" ","pages":""},"PeriodicalIF":0.9,"publicationDate":"2026-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149070124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy and toxicity of piroxicam rectal suppositories in palliative management of rectal carcinoma in dogs not receiving curative-intent surgery: A retrospective case series of eight dogs. 吡罗西康直肠栓剂对未接受治疗目的手术的犬直肠癌姑息治疗的疗效和毒性：回顾性8例犬的病例系列。

IF 0.9 3区农林科学

Veterinary Record Pub Date : 2026-09-19 Epub Date: 2025-12-17 DOI: 10.1002/vetr.70170

Isabelle Ng, Frances Taylor

{"title":"Efficacy and toxicity of piroxicam rectal suppositories in palliative management of rectal carcinoma in dogs not receiving curative-intent surgery: A retrospective case series of eight dogs.","authors":"Isabelle Ng, Frances Taylor","doi":"10.1002/vetr.70170","DOIUrl":"10.1002/vetr.70170","url":null,"abstract":"Background: The aim of this study was to report tolerability, safety and outcome in dogs with malignant epithelial rectal tumours receiving piroxicam suppositories where curative-intent surgery was not performed.Methods: Medical records from one UK referral hospital were retrospectively searched for dogs with malignant epithelial rectal tumours receiving piroxicam suppositories. Dogs receiving curative-intent surgery or anti-cancer agents were excluded. The primary outcomes were owner-reported improvement in clinical signs and veterinarian-assessed cRECIST (canine Response Evaluation Criteria for Solid Tumours) responses. The secondary outcomes recorded included overall survival time and progression-free survival.Results: Eight dogs were reported. Four patients experienced owner-reported clinical benefit, characterised by partial (n = 2) or complete (n = 2) resolution of clinical signs. Among these, three dogs had stable disease, and one dog achieved a complete response. Drug toxicity included hypersalivation (n = 1), vomiting (n = 2), elevations in renal markers (n = 2) and oliguric acute kidney injury (n = 1); the latter occurred 1248 days into therapy.Limitations: The small number of animals, owner-reported outcomes, non-standardised treatments and limited follow-up may affect the interpretation of the findings.Conclusions: Piroxicam suppositories improve clinical signs and may stabilise or reduce tumour volume in some dogs with rectal carcinomas where curative-intent surgery is not performed. Regular serum biochemistry monitoring is recommended due to the potential for renal toxicity.","PeriodicalId":23560,"journal":{"name":"Veterinary Record","volume":" ","pages":"e289-e297"},"PeriodicalIF":0.9,"publicationDate":"2026-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145775956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Benchmarking the herd-level passive transfer of immunity status of British dairy herds. 对英国奶牛群免疫状态的群体水平被动转移进行基准测试。

IF 0.9 3区农林科学

Veterinary Record Pub Date : 2026-09-19 DOI: 10.1002/vetr.71197

Julie MacFarlane

引用次数: 0

Effect of butorphanol in combination with xylazine during castration of calves: A randomised trial under field conditions. 丁托啡诺联合噻嗪对小牛去势的影响：一项野外随机试验。

IF 0.9 3区农林科学

Veterinary Record Pub Date : 2026-09-19 Epub Date: 2025-12-02 DOI: 10.1002/vetr.6017

Axel Sannö, Lovisa Snygg, Maja Wiklund, Görel Nyman

{"title":"Effect of butorphanol in combination with xylazine during castration of calves: A randomised trial under field conditions.","authors":"Axel Sannö, Lovisa Snygg, Maja Wiklund, Görel Nyman","doi":"10.1002/vetr.6017","DOIUrl":"10.1002/vetr.6017","url":null,"abstract":"Background: In horses, cats and dogs, the opioid butorphanol has been proven effective in management of visceral pain and for peri- and postoperative pain relief. The aim of this study was to evaluate physiological responses and indicators of noxious stimuli when adding butorphanol to xylazine for sedation of bull calves during surgical castration.Methods: In total, 54 bull calves were randomly assigned to a control group sedated with only xylazine and a treatment group sedated with the addition of butorphanol prior to castration. Observation of physiological responses by blinded observers from sedation and 1 hour onwards.Results: Apart from significantly more vocalisations in the treatment group prior, during and after the surgical procedure, no adverse effects of butorphanol addition were noted. Also, improved alertness and less drowsiness 1 hour after initiation of sedation were seen in the treatment group possibly associated with improved analgesia.Limitations: A longer follow-up time after sedation and additional measurements of cortisol levels would have given additional valuable information CONCLUSION: Addition of butorphanol leads to increased vocalisation during and possibly a shortened recovery time post-sedation.","PeriodicalId":23560,"journal":{"name":"Veterinary Record","volume":" ","pages":"e298-e303"},"PeriodicalIF":0.9,"publicationDate":"2026-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13587254/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145655747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Concurrent respiratory pathology and intracranial extension are common in companion rats (Rattus norvegicus) with otitis media/interna (23 cases, 2011-2025). 伴发中耳炎/内耳炎的褐家鼠（Rattus norvegicus）并发呼吸道病变和颅内扩张很常见（23例，2011-2025）。

IF 0.9 3区农林科学

Veterinary Record Pub Date : 2026-09-19 Epub Date: 2026-03-23 DOI: 10.1002/vetr.70496

Julianne E McCready, Ingeborg M Langohr, Trinita Barboza, Bianca Santana de Cecco, Fiona James, Fabio Del Piero, João Brandão

{"title":"Concurrent respiratory pathology and intracranial extension are common in companion rats (Rattus norvegicus) with otitis media/interna (23 cases, 2011-2025).","authors":"Julianne E McCready, Ingeborg M Langohr, Trinita Barboza, Bianca Santana de Cecco, Fiona James, Fabio Del Piero, João Brandão","doi":"10.1002/vetr.70496","DOIUrl":"10.1002/vetr.70496","url":null,"abstract":"Background: Otitis media/interna is well described in laboratory rats, but there is limited information on treatment and prognosis in pet rats.Methods: This was a retrospective, multi-institutional study of companion rats (Rattus norvegicus) presenting with otitis media/interna between 2011 and 2025. The inclusion criteria were rats diagnosed with otitis media/interna via imaging, necropsy or both. Information extracted from the medical records included signalment, clinical signs, diagnostic findings (including imaging, bloodwork, gross necropsy, histopathology and microbiology), treatment and survival time.Results: Twenty-three rats met the inclusion criteria. Twelve were diagnosed via necropsy alone, nine via imaging alone and two via both imaging and necropsy. Fifteen had clinical signs suspected to be due to otitis media/interna with or without otogenic intracranial disease. Seven had evidence of intracranial extension, such as meningoencephalitis or rhombencephalitis. Eighteen had concurrent respiratory disease. Bacterial culture (14/23) of lung, ear and/or brain samples revealed various bacteria, including Staphylococcus aureus (3/14). Mycoplasma was identified in six cases (three via PCR, two via culture and one via next-generation sequencing). Treatments included antibiotics (17/23), meloxicam (7/23), corticosteroids (3/23) and myringotomy (2/23). Survival ranged from 0 to 341 days.Limitations: This was a retrospective study, and case details and follow-up were limited in some cases.Conclusions: Over three-quarters of rats with otitis media/interna had concurrent respiratory disease and almost one-third had intracranial extension. Advanced imaging should therefore be considered in rats presenting with respiratory or neurological signs.","PeriodicalId":23560,"journal":{"name":"Veterinary Record","volume":" ","pages":"e278-e288"},"PeriodicalIF":0.9,"publicationDate":"2026-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147504992","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction to "Antimicrobial stewardship must begin at student level". 更正“抗菌药物管理必须从学生水平开始”。

IF 0.9 3区农林科学

Veterinary Record Pub Date : 2026-09-19 DOI: 10.1002/vetr.71173

引用次数: 0

Assessment of current colostrum feeding practices and passive transfer of immunity in dairy herds in Great Britain: A cross-sectional study. 英国奶牛群目前初乳喂养方法和被动免疫转移的评估：一项横断面研究。

IF 0.9 3区农林科学

Veterinary Record Pub Date : 2026-09-19 Epub Date: 2025-11-26 DOI: 10.1002/vetr.6025

George Lindley, Richard E Booth, D Claire Wathes, Nicola Blackie

{"title":"Assessment of current colostrum feeding practices and passive transfer of immunity in dairy herds in Great Britain: A cross-sectional study.","authors":"George Lindley, Richard E Booth, D Claire Wathes, Nicola Blackie","doi":"10.1002/vetr.6025","DOIUrl":"10.1002/vetr.6025","url":null,"abstract":"Background: Updated targets for measuring transfer of passive immunity (TPI) at the herd level have been suggested, but the current performance of dairy herds in Great Britain is unknown.Methods: A cross-sectional study was performed. Serum total protein (STP) data collected between October 2022 and October 2023 by 21 veterinary practices were benchmarked. Questionnaires were also distributed to collect information about colostrum feeding, calf husbandry and veterinary engagement, and associations between these factors and herd TPI were analysed using ordinal logistic regression.Results: A total of 4455 STP results from 91 herds were collected. Overall, 26% of calves had an STP concentration of less than 52 g/L (n = 1144). The number of herds with less than 10% of measured calves having an STP concentration of less than 51 g/L was 26% (n = 24). In contrast, 44% of herds (n = 40) recorded more than 40% calves having an STP concentration of 62 g/L or more. Herd TPI score was negatively associated with colostrum replacer feeding (odds ratio 0.09, 95% confidence interval: 0.01-0.54, p = 0.01).Limitations: A limited number of veterinarians and farmers completed the accompanying questionnaire, increasing the likelihood of Type I statistical error. Survey responses may be influenced by response bias.Conclusion: The overall herd TPI measured in the study was inadequate, suggesting that renewed emphasis on the optimisation of TPI within British dairy herds is necessary.","PeriodicalId":23560,"journal":{"name":"Veterinary Record","volume":" ","pages":"e262-e271"},"PeriodicalIF":0.9,"publicationDate":"2026-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13587255/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145640138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spontaneous vocalisation as a presenting clinical sign in dogs: An association with cervical localisation and intervertebral disc disease. 自发发声作为狗的临床表现：与颈椎定位和椎间盘疾病的关联。

IF 0.9 3区农林科学

Veterinary Record Pub Date : 2026-09-19 Epub Date: 2026-01-20 DOI: 10.1002/vetr.70222

Alex Spencer-Taylor, Sam Khan, Paul Freeman, Georgina Harris

{"title":"Spontaneous vocalisation as a presenting clinical sign in dogs: An association with cervical localisation and intervertebral disc disease.","authors":"Alex Spencer-Taylor, Sam Khan, Paul Freeman, Georgina Harris","doi":"10.1002/vetr.70222","DOIUrl":"10.1002/vetr.70222","url":null,"abstract":"Background: Spontaneous vocalisation is a common reason for dogs to be presented to veterinary practices. However, the cause can be unclear, making prioritisation of investigations challenging. Although vocalisation has been associated with syringomyelia, and anecdotally with cervical disc disease, the most common causes are not reported.Methods: The medical records of dogs presented at a single institution with spontaneous vocalisation between 2016 and 2022 were retrospectively analysed.Results: A total of 115 dogs were included. The most common breeds were crossbreeds (n = 23), Cavalier King Charles Spaniels (n = 10) and French Bulldogs (n = 9). Patients were most frequently referred to the neurology department (n = 93). Cervical myelopathy was most prevalent (n = 41), with a further 14 neurologically normal dogs with cervical hyperaesthesia. The most frequent diagnoses were intervertebral disc extrusion (n = 41), neoplasia (n = 9), intervertebral disc protrusion (n = 7), steroid-responsive meningitis arteritis (n = 7) and meningoencephalitis/myelitis of unknown origin (n = 6).Limitations: This was a retrospective analysis of patients within a single institution identified using terms within patient records, relying on comprehensive recording of information by the clinician at the time of presentation.Conclusions: In this cohort, spontaneous vocalisation most frequently localised to the cervical spine, with intervertebral disc extrusion as the most common diagnosis. This information may aid in clinical decision making, especially when advanced imaging is unavailable.","PeriodicalId":23560,"journal":{"name":"Veterinary Record","volume":" ","pages":"e272-e277"},"PeriodicalIF":0.9,"publicationDate":"2026-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146012427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0