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Coils associated with micro vascular plug system for closing larger vessels: Technical note on a preliminary experience.
IF 1 4区 医学
Vascular Pub Date : 2025-03-13 DOI: 10.1177/17085381251326997
Fabio Salvatori, Cinzia Mincarelli, Paola Piccinni, Salvatore Alborino
{"title":"Coils associated with micro vascular plug system for closing larger vessels: Technical note on a preliminary experience.","authors":"Fabio Salvatori, Cinzia Mincarelli, Paola Piccinni, Salvatore Alborino","doi":"10.1177/17085381251326997","DOIUrl":"https://doi.org/10.1177/17085381251326997","url":null,"abstract":"<p><p>ObjectivesThe MVP™ Micro Vascular Plug System represents a plug indicated for embolisation of peripheral vasculature. It has a lower profile and can be deliverable through smaller catheters, but it can occlude vessels ≤9 mm. We propose a new embolisation technique based on the use of the MVP™ and detachable coils to embolise vessels of larger calibre.Materials and methodsThrough a 7-F sheath the plug is implanted without detaching it. Then, the vessel is navigated in parallel with a microcatheter through which some coils are detached using the bare portion of the MVP™ to anchor them. This will stabilise the plug avoiding its distal migration. We performed vessel embolisation using this technique in two patients.ResultsTechnical success was 100% with no complications. No MPV™ migration was observed after one month.ConclusionsIn selected cases, this technique allows to expand the indications of the MVP™ when it is undersized to the calibre of the vessel.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"17085381251326997"},"PeriodicalIF":1.0,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143626163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment of femoropopliteal arterial lesions with excimer laser atherectomy and drug-coated balloon.
IF 1 4区 医学
Vascular Pub Date : 2025-03-11 DOI: 10.1177/17085381251326331
Zhijie Liao, Jinbao Qin, Linbo Liu, Heng Zhang, Qi Tang, Wentao Liu, Minyi Yin, Xinwu Lu, Yi Zhang
{"title":"Treatment of femoropopliteal arterial lesions with excimer laser atherectomy and drug-coated balloon.","authors":"Zhijie Liao, Jinbao Qin, Linbo Liu, Heng Zhang, Qi Tang, Wentao Liu, Minyi Yin, Xinwu Lu, Yi Zhang","doi":"10.1177/17085381251326331","DOIUrl":"https://doi.org/10.1177/17085381251326331","url":null,"abstract":"<p><p>ObjectivesProximal to mid-term effects of contrast excimer laser atherectomy (ELA) + drug-coated balloon (DCB) versus PTA + drug-coated balloon (DCB) in the treatment of new lesions in the femoral popliteal segment of patients with lower extremity arteriosclerosis and occlusion.MethodsThe clinical data of 105 patients with CT-confirmed femoropopliteal segment lesions (Rutherford grades 3-6) were retrospectively analyzed. According to the computerized randomization method, 58 patients (44 males, mean 72.41 ± 10.58 years) were divided into group A ELA + DCB dilation and 47 patients (35 males, mean 73.83 ± 11.56 years) in group B PTA + DCB dilation. The clinical indexes mainly included the occurrence of Rutherford grade, freedom from target lesion revascularization rate (FTLR), ankle-brachial index (ABI), stage I survival rate, and postoperative complications before, 6 months, and 12 months after surgery and were compared between the two groups.ResultsThe treatment success rate was 100% in all patients. The Rutherford grading at 12 months after operation was significantly improved in both groups, but statistical analysis showed that the improvement was more significant in group A (87.93% vs 72.34%, <i>p</i> = 0.043); ABI (0.77 ± 0.22<sup>abc</sup> vs 0.65 ± 0.10<sup>abc</sup>, <i>p</i> = 0.001); FTLR (93.10% vs 78.72%, <i>p</i> = 0.031), respectively. First-stage patency rate (91.38% vs 74.47%, <i>p</i> < 0.001),; complications, and adverse events were not statistically significant between the two groups (<i>p</i> > 0.05).ConclusionsELA + DCB significantly improved the 1-year freedom from target lesion revascularization rate and stage 1 patency rate with no significant increase in complications or adverse events.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"17085381251326331"},"PeriodicalIF":1.0,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mid-term outcomes of the fenestration, branched stent-graft, and hybrid techniques in the treatment of thoracic aortic pathologies involving the left subclavian artery.
IF 1 4区 医学
Vascular Pub Date : 2025-02-24 DOI: 10.1177/17085381241312468
Dongsheng Cui, Xiang Li, Zhian Liang, Junhang Chen, Jiaxin Wang, Jiayin Guo, Bin Zhao, Shuaishuai Wang, Peng Li, Jiaxue Bi, Xiangchen Dai
{"title":"Mid-term outcomes of the fenestration, branched stent-graft, and hybrid techniques in the treatment of thoracic aortic pathologies involving the left subclavian artery.","authors":"Dongsheng Cui, Xiang Li, Zhian Liang, Junhang Chen, Jiaxin Wang, Jiayin Guo, Bin Zhao, Shuaishuai Wang, Peng Li, Jiaxue Bi, Xiangchen Dai","doi":"10.1177/17085381241312468","DOIUrl":"https://doi.org/10.1177/17085381241312468","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objective: &lt;/strong&gt;To compare the midterm outcomes of fenestration, branched stent-graft thoracic endovascular aortic repair, and hybrid procedures in treating aortic arch pathologies involving the left subclavian artery.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;We collected the clinical data from 144 patients with aortic arch pathologies involving and only involving the left subclavian artery (LSA) who underwent fenestration, branched stent-graft thoracic endovascular aortic repair, and hybrid procedures from November 2015 and December 2022 at a single center. Among the patients, 68 were treated by fenestration, 61 by branched stent-grafts, and 15 by hybrid surgery. The clinical data was retrospectively analyzed and compared. The primary outcome indicators included technical success and in-hospital mortality; others included the incidence of endoleaks, spinal cord ischemia, LSA patency, stent-related entry tear, aortic-related reintervention, operative time, blood loss, and aortic remodeling.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The technical success rate was 83.8%, 95.1%, and 100% (&lt;i&gt;p&lt;/i&gt; = .046), and the in-hospital mortality rate was 1.5% (&lt;i&gt;n&lt;/i&gt; = 1), 0%, and 0% (&lt;i&gt;p&lt;/i&gt; = 1.000) in the fenestration, branched stent-graft, and hybrid surgery groups. Type I or III endoleaks occurred in 16.2% (&lt;i&gt;n&lt;/i&gt; = 11), 4.9% (&lt;i&gt;n&lt;/i&gt; = 3), and 0% of patients, respectively (&lt;i&gt;p&lt;/i&gt; = .046). The operative time, blood loss, and hospitalization duration of the hybrid surgery group was significantly higher than those of the other two groups (&lt;i&gt;p&lt;/i&gt; &lt; .05). However, the surgery-related costs and total costs in the hybrid surgery group were lower than the other two groups (&lt;i&gt;p&lt;/i&gt; &lt; .001). The rate of LSA patency was 100% in the fenestration group and 98.3% in the branched stent-graft group (&lt;i&gt;p&lt;/i&gt; = .475). The all-cause mortality rates were 10.9% (&lt;i&gt;n&lt;/i&gt; = 7), 6.9% (&lt;i&gt;n&lt;/i&gt; = 4), and 0%, respectively (&lt;i&gt;p&lt;/i&gt; = .359). Spinal cord ischemia and other complications were not significantly different in each group, both in the perioperative and postoperative periods. In the subgroup analysis of patients with AD, the incidence of endoleaks was 28.9% (&lt;i&gt;n&lt;/i&gt; = 13), 7.0% (&lt;i&gt;n&lt;/i&gt; = 3), and 0%, respectively (&lt;i&gt;p&lt;/i&gt; = .011), and stent-related new entry tears in each group were 2.2% (&lt;i&gt;n&lt;/i&gt; = 1), 18.6% (&lt;i&gt;n&lt;/i&gt; = 8), and 14.3% (&lt;i&gt;n&lt;/i&gt; = 1), respectively, &lt;i&gt;p&lt;/i&gt; = .032. The overall cumulative survival rate at 2 years was 90.0%, 92.4%, and 100%, respectively (&lt;i&gt;p&lt;/i&gt; = .508). The true lumen area of the aortic arch and descending thoracic aorta in the stent segment was significantly larger postoperatively compared to that preoperatively in both of these three groups.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;The fenestration technique is sophisticated with long learning curve and is prone to complications such as endoleaks with inexperience. Branched grafts are at greater risk of stent-related entry tears, which result in a higher rate of re-intervention. ","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"17085381241312468"},"PeriodicalIF":1.0,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143483630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Two-staged aortic repair for acute type A aortic dissection in patients refusing blood transfusion.
IF 1 4区 医学
Vascular Pub Date : 2025-02-17 DOI: 10.1177/17085381251321559
Tatsuya Watanabe, Takeyoshi Ota, Ross Milner, Valluvan Jeevanandam
{"title":"Two-staged aortic repair for acute type A aortic dissection in patients refusing blood transfusion.","authors":"Tatsuya Watanabe, Takeyoshi Ota, Ross Milner, Valluvan Jeevanandam","doi":"10.1177/17085381251321559","DOIUrl":"https://doi.org/10.1177/17085381251321559","url":null,"abstract":"<p><strong>Background: </strong>It is still challenging to perform high-risk cases, such as acute type A dissection, which frequently require blood transfusions. We created perioperative bloodless protocol, but it includes an optimization to increase the preoperative hemoglobin level enough to tolerate cardiopulmonary bypass. However, it would be impossible to optimize such patients using the strategy in the setting of emergent surgery. We sought to create a surgical strategy in an effort to reduce blood loss for acute type A dissection patients refusing blood transfusion.</p><p><strong>Methods: </strong>We reviewed the records of two patients in our aortic surgery database who presented with acute aortic dissection and refused blood transfusion. These patients underwent two-staged aortic repair with ascending aortic replacement with debranching to the innominate and left common carotid arteries, followed by thoracic endovascular aortic repair (TEVAR).</p><p><strong>Results: </strong><b>:</b> The two-staged procedure was successfully completed in two patients without any significant complication. The postoperative course was uneventful for both patients.</p><p><strong>Conclusion: </strong>Two-staged aortic repair in patients refusing blood transfusion can avoid circulatory arrest requiring deep hypothermia so as to reduce the risk of coagulopathy and blood loss.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"17085381251321559"},"PeriodicalIF":1.0,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143442010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hostile neck anatomy contributes to higher rates of reintervention following endovascular aortic repair for ruptured infrarenal abdominal aortic aneurysm. 对破裂的肾下腹主动脉瘤进行血管内主动脉修补术后,敌对颈部解剖结构会导致较高的再介入率。
IF 1 4区 医学
Vascular Pub Date : 2025-02-01 Epub Date: 2024-03-13 DOI: 10.1177/17085381241239428
Ryan Gedney, Christian Barksdale, Antwana Sharee Wright, Elizabeth A Genovese, Jean Marie Ruddy
{"title":"Hostile neck anatomy contributes to higher rates of reintervention following endovascular aortic repair for ruptured infrarenal abdominal aortic aneurysm.","authors":"Ryan Gedney, Christian Barksdale, Antwana Sharee Wright, Elizabeth A Genovese, Jean Marie Ruddy","doi":"10.1177/17085381241239428","DOIUrl":"10.1177/17085381241239428","url":null,"abstract":"<p><strong>Introduction: </strong>Ruptured abdominal aortic aneurysms (AAA) presenting with hostile neck anatomy can represent a challenge in surgical decision-making. We hypothesized that, patients who require reinterventions have higher rates of compromised neck anatomy at initial presentation and may indicate a need for altered surveillance paradigm.</p><p><strong>Methods: </strong>Patients presenting with ruptured AAA to a single tertiary care institution from 2014 to 2021 were retrospectively reviewed. Those treated with infrarenal EVAR, with no prior aortic surgeries, and with available pre-operative computed tomography (CT) scans were included. Demographics, timing and type of reintervention, follow-up, and survival were collected. CT scans were assessed for hostile neck anatomy via measurements of diameter, length, angle, taper, bulge, calcification, and thrombus. Demographics, comorbidities, and neck anatomy of those with and without reintervention were compared using Fischer's Exact and Student's T-test. Survival was analyzed via Kaplan-Meier and log-rank test.</p><p><strong>Results: </strong>Eighty-nine patients were available for analysis, 37 of which met inclusion criteria. Intraoperative death occurred in 3 patients (8.1%) and 1 patient (2.7%) was intraoperatively converted to an open repair. Thirty-day and 1-year survival were 97% and 91%, respectively. The reintervention rate was 30% (<i>n</i> = 10), occurring at a median of 200 days (18-2053 days) after the index operation. All patients requiring reintervention met hostile neck criteria (<i>p</i> = .002) and had a statistically higher number of hostile neck criteria (1.80 vs 0.87, <i>p</i> = .03). Thirty percent (<i>n</i> = 3) of patients that received a reintervention had neck diameter greater than 3 cm, compared to zero patients in the non-reintervention group (<i>p</i> = .022). Proximal reinterventions (<i>n</i> = 5) had statistically higher neck diameters and neck angle compared to the non-reintervention group.</p><p><strong>Conclusion: </strong>Infrarenal rEVAR is effective at preventing acute mortality despite specific anatomic considerations that may contribute to the higher reintervention rates, and therefore those parameters ought to be considered when following patients in the post-intervention period.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"132-138"},"PeriodicalIF":1.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11393178/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140120756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Conservative versus stent treatment for spontaneous isolated superior mesenteric artery dissection after the failure of initial 3 days' conservative treatment: A 10-year follow-up study. 自发孤立性肠系膜上动脉夹层在最初 3 天保守治疗失败后的保守治疗与支架治疗:10年随访研究。
IF 1 4区 医学
Vascular Pub Date : 2025-02-01 Epub Date: 2024-03-01 DOI: 10.1177/17085381241237125
Lei Wang, Miao Xu, Zhaolei Chen, Guoqing Jiang
{"title":"Conservative versus stent treatment for spontaneous isolated superior mesenteric artery dissection after the failure of initial 3 days' conservative treatment: A 10-year follow-up study.","authors":"Lei Wang, Miao Xu, Zhaolei Chen, Guoqing Jiang","doi":"10.1177/17085381241237125","DOIUrl":"10.1177/17085381241237125","url":null,"abstract":"<p><strong>Objectives: </strong>To compare the safety and effectiveness of conservative and stent treatment for spontaneous isolated superior mesenteric artery dissection (SISMAD) patients after the failure of initial 3 days' conservative treatment.</p><p><strong>Methods: </strong>All newly diagnosed SISMAD patients between 2013 and 2017 were retrospectively reviewed. After the failure of 3 days' conservative treatment, all patients were recommended for stent treatment, but some patients refused to choose it. Their demographic, radiologic, and clinical data were compared.</p><p><strong>Results: </strong>57 patients were not improved after initial 3 days' conservative treatment. Among them, 19 patients were chose to receive stent placement and 38 patients were continually treated with conservative treatment. The median follow-up time was 92.0 (range 62.7-120.4) months. There were no bowel ischemia and arterial rupture. No significant difference was observed in clinical complete recovery (Conservative 31/38 vs Stent 12/19, <i>p</i> =.19) and hospitalization time (Conservative 8.3 ± 1.7 days vs Stent 7.2 ± 1.5 days, <i>p</i> =.59) between conservative and stent treatment groups. Significant statistical differences were found in radiological complete remodeling (6/38 vs 16/19, <i>p</i> < .01) and hospitalization expense (8662 ± 2886 China Yuan vs 32,935 ± 11,767 China Yuan, <i>p</i> < .01) between these two groups.</p><p><strong>Conclusions: </strong>Although undergoing the failure of initial 3 days' conservative treatment, continue conservative treatment still is safe and effective for SISMAD patients. Stent placement could be chosen as an alternative treatment, especially for patients potentially with bowel ischemia or arterial rupture.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"96-101"},"PeriodicalIF":1.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140013365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Short-term patency of iliofemoral to tibial bypass with vascular allografts in a minority population: A retrospective analysis of a single center acute care facility. 在少数族裔人群中使用血管同种异体移植进行髂股骨至胫骨搭桥术的短期通畅性:对一家单中心急症护理机构的回顾性分析。
IF 1 4区 医学
Vascular Pub Date : 2025-02-01 Epub Date: 2024-03-05 DOI: 10.1177/17085381241237843
Max Murray-Ramcharan, Brian Donaldson, Syed Ali Raza Rizvi
{"title":"Short-term patency of iliofemoral to tibial bypass with vascular allografts in a minority population: A retrospective analysis of a single center acute care facility.","authors":"Max Murray-Ramcharan, Brian Donaldson, Syed Ali Raza Rizvi","doi":"10.1177/17085381241237843","DOIUrl":"10.1177/17085381241237843","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to examine the short-term patency rates and associated factors of open lower limb, iliofemoral to tibial bypass using cryopreserved saphenous vein (CSV) in a minority population at an acute care hospital in New York City.</p><p><strong>Methods: </strong>A retrospective analysis of patients undergoing infra-inguinal bypass from iliofemoral vessels to tibial arteries with CSV between March 2020-April 2022 at an acute care facility (Harlem Hospital Center, Harlem, New York) was performed. Data including patient demographics, comorbidities, type of operation, follow-up surveillance, and salvage procedures were collected. Results were presented in patency line graphs and a life table. Target limb revascularization (TLR) and amputation free survival (AFS) were also calculated.</p><p><strong>Results: </strong>Eleven bypass procedures were included in the analysis. Patients were followed for a mean of 10.8 months. Cumulative primary patency rates at 1, 6, and 12 months were 72.7%, 54.5%, and 40.9%, respectively. TLR was 36.4% and the AFS was 66.67% at the mean 10.8-month follow-up.</p><p><strong>Conclusions: </strong>The patency rates of minority patients undergoing bypass with CSV were analyzed with creation of a life table and calculation of patency rates, TLR and AFS. The short-term primary patency rates and post-operative outcomes were found to be comparable to larger studies in non-minority cohorts. These results suggest that larger studies as well as prospective analyses and randomized controlled trials in this patient cohort and demographic are needed, as well as optimal selection of patients to determine true clinical implications.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"66-72"},"PeriodicalIF":1.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140029055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Optimizing platelet inhibition in peripheral artery disease: A comparison of mono-antiplatelet therapy and dual-antiplatelet therapy using thromboelastography. 优化外周动脉疾病的血小板抑制:使用血栓弹性成像技术比较单抗血小板疗法和双抗血小板疗法。
IF 1 4区 医学
Vascular Pub Date : 2025-02-01 Epub Date: 2024-03-05 DOI: 10.1177/17085381241237005
Ivy Lee, Sasha Suarez, Ryan Hall, Monica Majumdar, Tiffany Bellomo, Samuel Jessula, Kathryn Nuzzolo, Douglas M Jefferson, Nikolaos Zacharias, Anahita Dua
{"title":"Optimizing platelet inhibition in peripheral artery disease: A comparison of mono-antiplatelet therapy and dual-antiplatelet therapy using thromboelastography.","authors":"Ivy Lee, Sasha Suarez, Ryan Hall, Monica Majumdar, Tiffany Bellomo, Samuel Jessula, Kathryn Nuzzolo, Douglas M Jefferson, Nikolaos Zacharias, Anahita Dua","doi":"10.1177/17085381241237005","DOIUrl":"10.1177/17085381241237005","url":null,"abstract":"<p><strong>Background: </strong>Antiplatelet therapy is used to prevent thrombosis in patients with peripheral artery disease (PAD) following revascularization. However, the current standard of care for these patients remains at the physician's discretion, varying from mono-antiplatelet therapy (MAPT) to dual-antiplatelet therapy (DAPT). Viscoelastic assays such as Thromboelastography with Platelet Mapping (TEG-PM) provide insight into individual coagulation profiles and measure real-time platelet function. This prospective, observational study looks at the differences in platelet function for patients on MAPT versus DAPT using TEG-PM.</p><p><strong>Methods: </strong>Patients with PAD undergoing revascularization were prospectively evaluated between December 2020 and June 2023. TEG-PM analysis compared platelet function for patients prescribed MAPT (aspirin or clopidogrel) at the initial encounter and DAPT (aspirin and clopidogrel) at the next visit. Platelet function measured in percent inhibition was evaluated at these visits, and within-group t-tests were performed.</p><p><strong>Results: </strong>Of the 195 patients enrolled, 486 samples were analyzed by TEG-PM. Sixty-four patients met the study criteria. At the initial visit, 52 patients had been prescribed aspirin, and 12 patients had been prescribed clopidogrel. For patients initially prescribed aspirin MAPT, an increase of 96.8%in the mean ADP platelet inhibition was exhibited when transitioning to DAPT [22.0% vs. 43.3%, <i>p <</i> .01], as well as an increase of 34.6%in the mean AA platelet inhibition when transitioning to DAPT [60.9% vs. 82.0%, <i>p <</i> .01]. For patients prescribed initial clopidogrel MAPT, an increase of 100% in AA platelet inhibition was exhibited on DAPT compared to the MAPT state [42.3% vs. 84.6%, <i>p < .</i>01].</p><p><strong>Conclusions: </strong>Patients on DAPT showed a significant increase in platelet inhibition when compared to initial aspirin MAPT. A significant difference in AA %platelet inhibition was shown for patients on DAPT when compared to initial clopidogrel MAPT. The results show that patients may benefit from DAPT post-revascularization. Personalizing antiplatelet therapy with objective viscoelastic testing to confirm adequate treatment may be the next step in optimizing patient outcomes to reduce thrombosis in PAD patients.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"3-18"},"PeriodicalIF":1.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140029054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Thoracic endovascular repair of descending thoracic aorta aneurysm using thoracic stent graft in a challenging complex patient: An innovative access technique during an emergency using a mini-thoracotomy approach. 使用胸腔支架移植物对具有挑战性的复杂患者进行降胸主动脉瘤的胸腔内血管修复:在急诊中使用微型胸廓切开术的创新入路技术。
IF 1 4区 医学
Vascular Pub Date : 2025-02-01 Epub Date: 2024-03-07 DOI: 10.1177/17085381241238041
Abdulmajeed Altoijry
{"title":"Thoracic endovascular repair of descending thoracic aorta aneurysm using thoracic stent graft in a challenging complex patient: An innovative access technique during an emergency using a mini-thoracotomy approach.","authors":"Abdulmajeed Altoijry","doi":"10.1177/17085381241238041","DOIUrl":"10.1177/17085381241238041","url":null,"abstract":"<p><strong>Objectives: </strong>Repairing thoracic aortic aneurysms with endovascular aortic repair (TEVAR) is a safe and minimally invasive method with low morbidity and short postoperative recovery. We developed a novel method to treat descending thoracic aortic aneurysms using a mini-thoracotomy approach in complex patients with difficult access.</p><p><strong>Methods: </strong>A 56-year-old male patient presented with a 3-day history of chest pain. His past surgical history included infrarenal aortic ligation and right axillobifemoral bypass. Thoracic computed tomography angiography (CTA) revealed a saccular aortic aneurysmal dilatation at zone 2 measuring 4.4 × 4 cm. Owing to his surgical history, vascular access through the femoral and iliac arteries or abdominal aorta was impossible. We developed a new technique using a left posterolateral mini-thoracotomy approach to gain vascular access and perform TEVAR, avoiding the need for an open thoracotomy repair.</p><p><strong>Results and conclusions: </strong>Thoracic CTA performed before discharge revealed complete aneurysmal exclusion and no endoleaks. Postoperative follow-up CTA (6 months and annually thereafter) revealed no aneurysm formation or aortic restenosis. The femoral artery, followed by the iliac artery, is the traditional access route for TEVAR. Left posterolateral mini-thoracotomy may be required as an alternative access in complex patients.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"127-131"},"PeriodicalIF":1.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140060663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
"Unveiling the invisible: Harnessing AI for carotid web diagnosis-A futuristic approach to enhance vascular healthcare". "揭开无形的面纱:利用人工智能进行颈动脉网络诊断--加强血管医疗保健的未来主义方法"。
IF 1 4区 医学
Vascular Pub Date : 2025-02-01 Epub Date: 2024-03-04 DOI: 10.1177/17085381241238042
Michael James, Viren S Sehgal, Rooshi Parikh
{"title":"\"Unveiling the invisible: Harnessing AI for carotid web diagnosis-A futuristic approach to enhance vascular healthcare\".","authors":"Michael James, Viren S Sehgal, Rooshi Parikh","doi":"10.1177/17085381241238042","DOIUrl":"10.1177/17085381241238042","url":null,"abstract":"","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"238-239"},"PeriodicalIF":1.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140029052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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