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Hybrid aorto-iliac reconstruction for acute infrarenal aortic occlusion: A case report. 急性肾下主动脉闭塞的髂主动脉混合重建术:病例报告。
IF 0.9 4区 医学
Vascular Pub Date : 2025-10-01 Epub Date: 2024-08-14 DOI: 10.1177/17085381241273272
Sarah A Loh, Edouard Aboian
{"title":"Hybrid aorto-iliac reconstruction for acute infrarenal aortic occlusion: A case report.","authors":"Sarah A Loh, Edouard Aboian","doi":"10.1177/17085381241273272","DOIUrl":"10.1177/17085381241273272","url":null,"abstract":"<p><p>ObjectiveAcute aortic occlusion (AAO), though rare, carries a high morbidity and mortality risk. Rapid recognition and revascularization are crucial for limb and life preservation. We present a case of a hybrid approach using open thrombectomy and endovascular arterial stent grafts in lieu of an open bypass for management of AAO.MethodsThis case describes a 77-year-old man who presented with new-onset lower extremity pain with associated sensory deficits and was found to have acute infrarenal aortic occlusion. Open femoral cutdown for open thrombectomy and distal embolic protection with endovascular balloon occlusion was combined with aortic and bilateral iliac artery stenting.ResultsThe patient was discharged home on post-operative day 3 with resolution of his presenting symptoms and remains asymptomatic at 1-month follow-up.ConclusionThis technique of aorto-iliac reconstruction using stent grafts has previously been described in the setting of chronic aorto-iliac occlusive disease; however, its use has not been previously documented in the setting of acute aortic occlusion. This case illustrates the safety and feasibility of a hybrid approach to AAO, particularly in patients who are physiologically unfit for open revascularization.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"1032-1036"},"PeriodicalIF":0.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141983354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Injury of the superficial femoral artery and posterior tibial artery associated with an atherectomy device. 股浅动脉和胫后动脉损伤与动脉粥样硬化切除装置有关。
IF 0.9 4区 医学
Vascular Pub Date : 2025-10-01 Epub Date: 2024-08-21 DOI: 10.1177/17085381241276608
Ahmed M Afifi, Samuel C Dunseith, Munier Nazzal
{"title":"Injury of the superficial femoral artery and posterior tibial artery associated with an atherectomy device.","authors":"Ahmed M Afifi, Samuel C Dunseith, Munier Nazzal","doi":"10.1177/17085381241276608","DOIUrl":"10.1177/17085381241276608","url":null,"abstract":"<p><p>ObjectivesRotational atherectomy can offer a viable treatment for occlusive peripheral artery disease; maintaining the minimal invasiveness of an endovascular procedure, while allowing for a more complete lesion debridement compared with balloon angioplasty. This case report outlines a complication of guidewire entrapment associated with rotational atherectomy in the superficial femoral artery (SFA).MethodsA 57-year-old male underwent an atherectomy with Rotorex for left lower limb foot pain. During the procedure, the guidewire was suctioned into the atherectomy device, preventing any further advancement of the device and damaging the SFA and posterior tibial artery (PTA).ResultsThe atherectomy device was withdrawn and a new vascular access site was gained in the left PTA. A covered stent was inserted to treat the original SFA lesion, and balloon angioplasty was used to repair the device-induced damaged to the PTA.ConclusionWhile guidewire complications have been previously reported, this case report details the first reported case, to our knowledge, of guidewire entrapment while using a rotational atherectomy device. Knowledge of this possible complication of rotational atherectomy can aid in clinical decision making when choosing between treatments for peripheral vascular disease.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"1141-1149"},"PeriodicalIF":0.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142018795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploration of small molecule compounds targeting abdominal aortic aneurysm based on CMap database and molecular dynamics simulation. 基于 CMap 数据库和分子动力学模拟探索针对腹主动脉瘤的小分子化合物。
IF 0.9 4区 医学
Vascular Pub Date : 2025-10-01 Epub Date: 2024-08-18 DOI: 10.1177/17085381241273289
Fushan Li, Liqing Zhuo, Fangtao Xie, Haiping Luo, Ying Li, Huyu Lin, Xiaoguang Li
{"title":"Exploration of small molecule compounds targeting abdominal aortic aneurysm based on CMap database and molecular dynamics simulation.","authors":"Fushan Li, Liqing Zhuo, Fangtao Xie, Haiping Luo, Ying Li, Huyu Lin, Xiaoguang Li","doi":"10.1177/17085381241273289","DOIUrl":"10.1177/17085381241273289","url":null,"abstract":"<p><p>ObjectiveThe mitigation of abdominal aortic aneurysm (AAA) growth through pharmaceutical intervention offers the potential to avert the perils associated with AAA rupture and the subsequent need for surgical intervention. Nevertheless, the existing effective drugs for AAA treatment are limited, necessitating a pressing exploration for novel therapeutic medications.MethodsAAA-related transcriptome data were downloaded from GEO, and differentially expressed genes (DEGs) in AAA tissue were screened for GO and KEGG enrichment analyses. Small molecule compounds and their target proteins with negative connectivity to the AAA expression profile were predicted in the Connectivity Map (CMap) database. Molecular docking and molecular dynamics simulation were performed to predict the binding of the target protein to the small molecule compound, and the MM/GBSA method was used to calculate the binding free energy. Cluster analysis was performed using the cluster tool in the GROMACS package. An AAA cell-free model was built, and CETSA experiments were used to demonstrate the binding ability of small molecules to the target protein in cells.ResultsA total of 2244 DEGs in AAA were obtained through differential analysis, and the DEGs were mainly enriched in the tubulin binding biological function and cell cycle pathway. The CMap results showed that Apicidin had a potential therapeutic effect on AAA with a connectivity score of -97.74, and HDAC4 was the target protein of Apicidin. Based on literature, HDAC4-Apicidin was selected as the subsequent research object. The lowest affinity of Apicidin-HDAC4 molecular docking was -8.218 kcal/mol. Molecular dynamics simulation results indicated that Apicidin-HDAC4 could form a stable complex. MM/GBSA analysis showed a total binding free energy of -55.40 ± 0.79 kcal/mol, and cluster analysis showed that there were two main conformational clusters during the binding process, accounting for 22.4% and 57.8%, respectively. Apicidin could form hydrogen bonds with surrounding residues for stable binding. CETSA experiment proved the stable binding ability of Apicidin and HDAC4.ConclusionApicidin inhibited HDAC4 in AAA and exhibited favorable protein-ligand interactions and stability, making it a potential candidate drug for treating AAA.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"1037-1048"},"PeriodicalIF":0.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142000751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Safety and efficacy of endovenous microwave ablation for treatment of varicose veins of the lower limbs in China: A prospective registered clinical trial. 中国静脉内微波消融治疗下肢静脉曲张的安全性和有效性:前瞻性注册临床试验。
IF 0.9 4区 医学
Vascular Pub Date : 2025-10-01 Epub Date: 2024-08-26 DOI: 10.1177/17085381241273225
Lifeng Zhang, Yao Lin, Caijuan Geng, Wei Huang, Qifan Yang, Chunshui He, Wei Zeng
{"title":"Safety and efficacy of endovenous microwave ablation for treatment of varicose veins of the lower limbs in China: A prospective registered clinical trial.","authors":"Lifeng Zhang, Yao Lin, Caijuan Geng, Wei Huang, Qifan Yang, Chunshui He, Wei Zeng","doi":"10.1177/17085381241273225","DOIUrl":"10.1177/17085381241273225","url":null,"abstract":"<p><p>ObjectiveThis study aimed to investigate the safety and efficacy of a new Chinese device using microwave ablation for treating symptomatic great saphenous vein (GSV) varicose veins (VVs).MethodsThis prospective, single-arm, single-center, cohort study investigated the safety and efficacy of endovenous microwave ablation for the treatment of symptomatic VVs. A total of 50 patients with lower limb varicose veins were enrolled from the Hospital of Chengdu University of Traditional Chinese Medicine. The clinical outcomes and complications were assessed at 1, 6, and 12 months after the procedure. The primary outcome was the occlusion rate of GSV immediately and at 1, 6, and 12 months after the treatment. The secondary outcomes included the venous clinical severity score (VCSS), the chronic venous insufficiency questionnaire 14 items (CIVIQ-14) score, the Aberdeen varicose vein questionnaire (AVVQ) score, and the pain visual analog scale (VAS) score. This study protocol was registered at ClinicalTrials.gov (ID: NCT04645771).ResultsIn total, 50 limbs from 50 patients (26 female; mean age: 53.45 ± 9.78 years) were treated. A technical success rate of 100% was achieved and no serious adverse events were recorded. During the follow-up period, the occlusion rate of the major/minor saphenous vein trunk remained 100% at 1, 6, and 12 months after surgery except one patient fell off. The median 24-h VAS value was 2 (2,3). The VCSS score, CIVIQ-14 score, and AVVQ score (<i>p</i> < .05) at 1, 6, and 12 months improved significantly compared with the value preoperative (<i>p</i> < .05).ConclusionEMA was safe and effective for treating varicose veins in the lower limbs, with a high rate of venous trunk occlusion and few complications, thus improving patients' postoperative quality of life.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"1011-1019"},"PeriodicalIF":0.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142056644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful use of lithoplasty for re-expansion of covered iliac stents with unilateral occlusion. 成功使用碎石术为单侧闭塞的带盖髂骨支架重新扩张。
IF 0.9 4区 医学
Vascular Pub Date : 2025-10-01 Epub Date: 2024-08-30 DOI: 10.1177/17085381241280458
Fachreza A Damara, Matthew Wolfers, Lee Kirksey
{"title":"Successful use of lithoplasty for re-expansion of covered iliac stents with unilateral occlusion.","authors":"Fachreza A Damara, Matthew Wolfers, Lee Kirksey","doi":"10.1177/17085381241280458","DOIUrl":"10.1177/17085381241280458","url":null,"abstract":"<p><strong>Background: </strong>Vessel wall calcification is associated with stent under-expansion and in-stent restenosis. The traditional approaches to treat peripheral artery calcification are percutaneous transluminal angioplasty (PTA) and atherectomy. Shockwave intravascular lithotripsy (IVL) uses sonic wave pressure to disrupt calcium of the severely calcified lesions. Published reports of IVL to treat in-stent restenosis are limited to coronary interventions and bare metal platforms.MethodsWe describe the case of a 55-year-old male with extremely compressed under-expanded covered stents associated with severe wall calcification that resulted in stent occlusion.ResultsThe IVL system balloon was deployed uneventfully, in a phased manner. Bilateral bare metal stents were also placed in a kissing fashion to further re-expand the arterial segments. Reintervention with IVL facilitated successful revascularization and the stent remained patent at 24 months.ConclusionOur case highlights the use of IVL as an effective tool in the management of vessel wall calcification both for primary and secondary interventions.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"1097-1101"},"PeriodicalIF":0.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142112491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The jailed coiling technique: An endovascular solution for saccular aneurysms with suboptimal fixation sites. 狱式卷绕技术:针对固定部位不理想的囊状动脉瘤的血管内解决方案。
IF 0.9 4区 医学
Vascular Pub Date : 2025-10-01 Epub Date: 2024-08-30 DOI: 10.1177/17085381241273269
Daniel Silverberg, Avner Bar-Dayan, Daniel Raskin, Sami Canani, Moshe Halak
{"title":"The jailed coiling technique: An endovascular solution for saccular aneurysms with suboptimal fixation sites.","authors":"Daniel Silverberg, Avner Bar-Dayan, Daniel Raskin, Sami Canani, Moshe Halak","doi":"10.1177/17085381241273269","DOIUrl":"10.1177/17085381241273269","url":null,"abstract":"<p><p>ObjectiveTo evaluate the midterm results of patients with saccular aneurysms treated with the jailed coiling technique.MethodsA retrospective review of 17 patients treated with the jailed coiling technique over a 7 year period, between 2018 and 2024 at our institution. Treatment entails placing an endograft across the neck of the saccular aneurysm followed by coiling of the aneurysm through an extraluminal catheter. Debranching procedures of the aortic arch were performed when necessary in order to create a sealing zone of >5 mm. Data collected included demographics, anatomical features of the lesions and sealing zones, indication for intervention, method of treatment and technical success, sac expansion, and reinterventions.Results17 patients (median age 69, 14 males) were treated for saccular aneurysms with short, suboptimal sealing zones (aortic arch 13, distal thoracic aorta 2, celiac trunk 1, brachiocephalic artery 1). Among the aortic arch aneurysms, six required preoperative debranching procedures of the aortic arch in order to create a short landing zone of 5 mm, making them eligible for the procedure. Technical success was obtained in all patients. One perioperative mortality occurred. Mean follow-up among those treated for arch aneurysms was 32 months (range 1-71 months). One patient who was treated for an aortic arch aneurysm had a persistent endoleak. No sac enlargement was observed. None of the patients required interventions and none experienced aneurysm related mortality.ConclusionThe jailed coiling technique is a safe and effective method to treat saccular arterial aneurysms with suboptimal, short sealing zones. It can be utilized for saccular aneurysms located within the aortic arch and for aneurysms located in other locations where coiling or stent grafting is not an option. The procedure can be performed with minimal morbidity with a high percentage of success. Long term durability of the repair needs to be determined.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"1074-1080"},"PeriodicalIF":0.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142112492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predictors for thoracic aortic growth in patients with type B aortic dissection after thoracic endovascular aortic repair. B 型主动脉夹层患者胸腔内血管主动脉修复术后胸腔主动脉生长的预测因素。
IF 0.9 4区 医学
Vascular Pub Date : 2025-10-01 Epub Date: 2024-08-14 DOI: 10.1177/17085381241273233
Yonghui Chen, Jianli Ren, Zongwei Liu, Dongsheng Cui, Shuaishuai Wang, Jiaxue Bi, Xiangchen Dai
{"title":"Predictors for thoracic aortic growth in patients with type B aortic dissection after thoracic endovascular aortic repair.","authors":"Yonghui Chen, Jianli Ren, Zongwei Liu, Dongsheng Cui, Shuaishuai Wang, Jiaxue Bi, Xiangchen Dai","doi":"10.1177/17085381241273233","DOIUrl":"10.1177/17085381241273233","url":null,"abstract":"<p><p>ObjectiveTo identify independent predictors of thoracic aortic growth in patients with type B aortic dissection (TBAD) undergoing thoracic endovascular aortic repair (TEVAR).MethodsA retrospective analysis of the patients undergoing TEVAR for TBAD or intramural hematoma (IMH) from April 2014 to April 2023 was performed. The baseline morphological data of TBAD was established through computed tomography angiography (CTA) before discharge. Patients were divided into two groups based on aortic growth: growth and no growth. Aortic growth defined as an increase ≥5 mm in thoracic maximal aortic diameter during any serial follow-up CTA measurement. Logistic regression following propensity score matching (PSM) was used to identify independent predictors for aortic growth. Receiver operating characteristic curve and cutoff value of independent predictors were calculated. Linear regression was used to establish a correlation between anatomical variables and follow-up aortic diameter.ResultsA total of 145 patients with TBAD (<i>n</i> = 122) or IMH (<i>n</i> = 23) undergoing TEVAR were included, with a male of 83.4% and a mean age of 56 ± 14.1 years. Patients in growth group and no growth group was 26 (17.9%) and 119 (80.1%), respectively. After using PSM method, matched regression analysis showed residual maximal tear diameter (OR = 0.889, 95% CI 0.830-0.952, <i>p</i> = 0.001) and follow-up aortic diameter (OR = 0.977, 95% CI 0.965-0.989, <i>p</i> < 0.001) were independent predictors for aortic growth. The cutoff value was 8.55 mm for residual tear diameter and 40.65 mm for follow-up maximal aortic diameter. The residual maximal tear diameter showed a linear correlation with follow-up aortic diameter (DW = 1.74, R2 = 6.2%, <i>p</i> = 0.033).ConclusionsThis study suggested that residual maximal tear diameter >8.55 mm and follow-up aortic diameter >40.65 mm could predict aortic growth in patients with TBAD undergoing TEVAR.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"1020-1027"},"PeriodicalIF":0.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141976741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Redefining the exact roles and importance of carotid intima-media thickness and carotid plaque thickness in predicting cardiovascular events. 重新定义颈动脉内膜厚度和颈动脉斑块厚度在预测心血管事件中的确切作用和重要性。
IF 0.9 4区 医学
Vascular Pub Date : 2025-10-01 Epub Date: 2024-08-19 DOI: 10.1177/17085381241273293
Dusan J Petrovic
{"title":"Redefining the exact roles and importance of carotid intima-media thickness and carotid plaque thickness in predicting cardiovascular events.","authors":"Dusan J Petrovic","doi":"10.1177/17085381241273293","DOIUrl":"10.1177/17085381241273293","url":null,"abstract":"<p><p>ObjectiveThe survey aimed to evaluate the precise roles and importance of carotid plaque thickness and carotid intima-media thickness measured in plaque-free areas (PF CC-IMTmean) in future cardiovascular risk prediction.Material and methods188 respondents between the age of 46 and 87 divided into two groups (I group - 94 respondents without plaques with CIMT measurement and II Group 94 respondents with carotid plaques; 118 men and 70 women; mean age ± SD, 61.80 ± 5.49) were prospectively examined by the carotid ultrasound Doppler (carotid measurements included plaque thickness PT - nonstenotic plaques (carotid stenosis <50%) and stenotic culprit plaques (carotid stenosis ≥50%), mean CIMT and maximum CIMT). Subjects were followed for 36 months from the inclusion in the study (regular control examinations). Data were recorded on new cases of mortality (CV mortality) and adverse CV events (myocardial infarction - -MI, surgical or endovascular revascularization - coronary or stroke).ResultsIn this study, CIMT values vary between 0.62 and 1.43 mm (mean CIMT = 1.21 ± 0.2 mm) while 52 subjects had nonstenotic plaques (14 respondents plaque ulceration, 22 type 2 diabetes mellitus, 38 arterial hypertension) and 38 subjects had stenotic culprit plaques (17 respondents plaque ulceration, 20 type 2 diabetes mellitus, 31 arterial hypertension). After 36 months of follow-up, 76 vascular events were noted (MI, transient ischaemic attack - TIA, stroke and cardiovascular angioplasty or surgery) in this period.ConclusionRespondents with carotid plaques had higher cardiovascular events occurrence (<i>p</i> < .01, high statistical difference). Carotid plaques as a parameter have higher predictive vascular event value importance than CIMT. Of note, stenotic plaques, the presence of ulceration on the free surface of the plaque, type 2 diabetes mellitus and hypertension were connected with the highest events occurrence.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"1200-1207"},"PeriodicalIF":0.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142000764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Malnutrition is associated with adverse 30-day outcomes after endovascular repair of abdominal aortic aneurysm. 营养不良与腹主动脉瘤血管内修复术后 30 天的不良预后有关。
IF 0.9 4区 医学
Vascular Pub Date : 2025-10-01 Epub Date: 2024-09-27 DOI: 10.1177/17085381241289484
Renxi Li, Anton Sidawy, Bao-Ngoc Nguyen
{"title":"Malnutrition is associated with adverse 30-day outcomes after endovascular repair of abdominal aortic aneurysm.","authors":"Renxi Li, Anton Sidawy, Bao-Ngoc Nguyen","doi":"10.1177/17085381241289484","DOIUrl":"10.1177/17085381241289484","url":null,"abstract":"<p><p>BackgroundMalnutrition is particularly pertinent in patients undergoing vascular surgery, who frequently present with a high burden of comorbidities and advanced age that can impede nutrient absorption. While previous studies have established that vascular surgery patients with malnutrition had poorer outcomes, the impact of nutritional status in patients undergoing endovascular aneurysm repair (EVAR) has not yet been investigated. Therefore, this study aimed to assess the effect of malnutrition on 30-day outcomes following non-ruptured EVAR.MethodsPatients who had infrarenal EVAR were identified in the ACS-NSQIP targeted database from 2012-2022. Exclusion criteria included age less than 18 years, ruptured aneurysm, and emergency. Malnutrition was defined as patients with preoperative weight loss of greater than 10% decrease in body weight in the 6 months immediately preceding the surgery. A 1:5 propensity-score matching was used to match demographics, baseline characteristics, aneurysm diameter, distant aneurysm extent, anesthesia, and concomitant procedures between patients with and without malnutrition. Thirty-day postoperative outcomes were examined.ResultsThere were 154 (0.94%) patients with malnutrition who went under non-ruptured EVAR. Meanwhile, 16,309 patients without malnutrition went under intact EVAR, where 737 of them were matched to all malnutrition patients. Malnourished patients had more comorbidity burdens. After propensity-score matching, patients with malnutrition had elevated but non-significant 30-day mortality (5.92% vs 2.99%, <i>p</i> = .09). However, malnutrition patients had higher risks of renal complications (2.63% vs 0.68%, <i>p</i> = .04), bleeding requiring transfusion (22.37% vs 14.38%, <i>p</i> = .02), and unplanned reoperation (11.18% vs 4.88%, <i>p</i> = .01), as well as longer length of stay (6.11 ± 7.91 vs 4.44 ± 6.22 days, <i>p</i> < .02).ConclusionPatients with malnutrition experienced higher rates of morbidity after non-ruptured EVAR. Targeting malnutrition could be a strategy for preventing complications after EVAR and proper preoperative malnutritional management could be warranted.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"1058-1065"},"PeriodicalIF":0.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142354777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The immediate post-operative impact of infrarenal aortic endografts on renal arterial flow dynamics: Insights from four-dimensional flow magnetic resonance imaging analysis. 肾下主动脉内膜移植术后对肾动脉血流动力学的直接影响:四维血流磁共振成像分析的启示。
IF 0.9 4区 医学
Vascular Pub Date : 2025-10-01 Epub Date: 2024-08-23 DOI: 10.1177/17085381241277651
Masayuki Sugimoto, Ryota Horiguchi, Shuta Ikeda, Yohei Kawai, Kiyoaki Niimi, Ryota Hyodo, Hiroshi Banno
{"title":"The immediate post-operative impact of infrarenal aortic endografts on renal arterial flow dynamics: Insights from four-dimensional flow magnetic resonance imaging analysis.","authors":"Masayuki Sugimoto, Ryota Horiguchi, Shuta Ikeda, Yohei Kawai, Kiyoaki Niimi, Ryota Hyodo, Hiroshi Banno","doi":"10.1177/17085381241277651","DOIUrl":"10.1177/17085381241277651","url":null,"abstract":"<p><p>ObjectivesThis study aims to quantify changes in renal blood flow before and after endovascular aneurysm repair (EVAR) using four-dimensional (4D) flow magnetic resonance imaging (MRI) and evaluate its correlation with renal impairment.MethodsIn this retrospective analysis, 18 patients underwent elective EVAR for infrarenal fusiform abdominal aortic aneurysms using Excluder or Endurant endografts. 4D flow MRI scans were conducted before and 1-4 days after EVAR. Hemodynamics were quantified at the suprarenal aorta (SupAo), bilateral renal arteries (RRA and LRA), and infrarenal aorta (InfAo). Cardiac phase-resolved blood flow values (BFVs), relative flow distribution (RFD), and flow change rates (FCRs) were assessed. Estimated glomerular filtration rate (eGFR) was measured pre- and postoperatively.ResultsA total of 16 patients were analyzed after excluding two outliers. Pre-EVAR BFVs were 23.1 ± 8.3, 3.7 ± 1.3, 3.4 ± 1.2, and 15.1 ± 5.9 mL/cycle, while post-EVAR BFVs were 20.9 ± 6.9, 3.8 ± 1.1, 3.2 ± 0.9, and 12.1 ± 4.3 mL/cycle in SupAo, RRA, LRA, and InfAo, respectively. Comparing Excluder (N = 8) and Endurant (N = 8), the total renal FCR was 121.8% [106.6-144.7] versus 101.3% [63.8-121.8] (<i>p</i> = 0.110), suggesting a potential improvement in renal blood flow with the Excluder, although not statistically significant. A significant correlation was found between the total renal FCR and the relative eGFR at 6 months (Spearman correlation coefficient, 0.789; <i>p</i> < 0.001).ConclusionsThe endografts, particularly the Excluder, showed potential in improving renal artery blood flow in some patients. The significant correlation between the total renal FCR and the relative eGFR at 6 months suggests that acute hemodynamic alterations induced by EVAR may impact post-operative renal function. Further research is needed to confirm these findings and assess their clinical implications.</p>","PeriodicalId":23549,"journal":{"name":"Vascular","volume":" ","pages":"1049-1057"},"PeriodicalIF":0.9,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142047269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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