Veterinary Pathology最新文献_第2页

Spontaneous IgM glomerulopathy in female athymic nude sentinel mice. 雌性胸腺裸哨小鼠自发性IgM肾小球病变。

IF 1.7 2区农林科学

Veterinary Pathology Pub Date : 2026-05-01 Epub Date: 2026-03-04 DOI: 10.1177/03009858261423110

Marietta V Barro, Qian J Chen, Anibal G Armien, Laurie Brignolo, Denise M Imai

{"title":"Spontaneous IgM glomerulopathy in female athymic nude sentinel mice.","authors":"Marietta V Barro, Qian J Chen, Anibal G Armien, Laurie Brignolo, Denise M Imai","doi":"10.1177/03009858261423110","DOIUrl":"10.1177/03009858261423110","url":null,"abstract":"Female Hsd:Athymic nude-Foxn1nu sentinel mice spontaneously develop a life-limiting protein-losing nephropathy. We aimed to characterize this disease and identify risk factors. Affected mice presented with anasarca and pale tan, irregularly pitted kidneys. Histologically, glomeruli were distorted by eosinophilic, hyaline, mesangial deposits. Additional non-specific glomerular changes included synechiae, periglomerular fibrosis, and capillary thrombosis. Ectatic tubules with attenuated epithelium and tubular casts and interstitial inflammation were also present. Mesangial deposits were Congo red (CR)-negative, periodic acid-Schiff-positive, and pale blue to pink using Masson's trichrome stain. The glomerular basement membrane was mildly irregular using Jones' methenamine silver stain. The mesangial deposits were immunoglobulin G (IgG)- and immunoglobulin A (IgA)-immunonegative and immunoglobulin m (IgM)-immunopositive. Ultrastructurally, subendothelial electron-dense deposits were composed of straight and curved linear, 30 to 170 nm diameter tubular, and 9 to 16 nm diameter fibrillary profiles. Together, these findings were consistent with hyaline glomerulopathy due to IgM deposition. Prevalence of the disease over 6 years was 0.6% (75/13 042 homozygous sentinel mice). Vivarium biosecurity level, infectious disease screening results, and comorbidities were evaluated in 75 female, 6-month-old, homozygous nude sentinel mice with hyaline glomerulopathy and 75 without. Neither biosecurity level nor pathogen diversity was risk factors. However, sentinel mice with auto-inflammatory conditions, such as proliferative typhlocolitis (P = .005) and dermatitis (P = .03), and with lymphoid neoplasia (lymphoma; P = .0007) had a lower risk of developing hyaline glomerulopathy. Our results support the diagnosis of hyaline glomerulopathy in young adult, female, nude sentinel mice and help recognize this spontaneous condition in a canonical immunodeficient research model.","PeriodicalId":23513,"journal":{"name":"Veterinary Pathology","volume":" ","pages":"500-511"},"PeriodicalIF":1.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147356608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Techniques to study chimerism at the tissue level in humanized mice. 人源化小鼠组织水平嵌合研究技术。

IF 1.7 2区农林科学

Veterinary Pathology Pub Date : 2026-05-01 Epub Date: 2025-11-21 DOI: 10.1177/03009858251386916

Arin Cox, Esha Banerjee, Jillian Verrelle, Elinor Willis, Charles-Antoine Assenmacher, Giovanni Finesso, James C Tarrant, Enrico Radaelli

{"title":"Techniques to study chimerism at the tissue level in humanized mice.","authors":"Arin Cox, Esha Banerjee, Jillian Verrelle, Elinor Willis, Charles-Antoine Assenmacher, Giovanni Finesso, James C Tarrant, Enrico Radaelli","doi":"10.1177/03009858251386916","DOIUrl":"10.1177/03009858251386916","url":null,"abstract":"Understanding the origin, distribution, and biology of different cell populations in chimeric mice is critical for interpreting the pathological changes developed in these models. To this aim, the methodological work presented here illustrates the validation and application of a collection of labeling techniques to differentiate between specific mouse and human tissue/cell components in formalin-fixed paraffin-embedded samples from chimeric mice, especially those bearing human tumor and immune cells. First, broad approaches to identify cells of human origin using ubiquitous immunohistochemical targets such as HLA-A, Ku80, and human mitochondrial 60 kDa protein (hMito) were established using specimens from humanized mice and a human tissue microarray including both normal and neoplastic samples. Due to its crisp membranous immunoreactivity, HLA-A was the most useful marker for visual human cell identification; however, Ku80 and hMito may be suitable options when HLA-A is not expressed in the cells of interest. Importantly, using one or more of these markers provides a broad range of coverage for the vast majority of human-derived cells in chimeric mice. Second, tailored immunohistochemical or in situ hybridization methodologies to distinguish specific human or mouse cell subsets are presented, focusing on immune/inflammatory cells and human chimeric antigen receptor (CAR) T-cells. These diverse approaches are accompanied by descriptions of case examples highlighting practical diagnostic and experimental applications in the context of various humanized mouse models. While not comprehensive, this work represents a valuable starting reference for pathologists and investigators working with humanized mouse models and seeking to add spatial resolution to the complex landscape of chimeric tissues.","PeriodicalId":23513,"journal":{"name":"Veterinary Pathology","volume":" ","pages":"478-489"},"PeriodicalIF":1.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13036268/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145565532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spontaneous clinical and anatomical pathology findings in SDRG rats. SDRG大鼠自发性临床及解剖病理表现。

IF 1.7 2区农林科学

Veterinary Pathology Pub Date : 2026-05-01 Epub Date: 2026-03-04 DOI: 10.1177/03009858261423163

Valeria Bertani, Lucia Minoli, Anna de Battisti, Alice Cantachin, Giuliano Turrini, Giulia Forcellini, Riccardo Bazzoni, Anna Slaviero, Leila Abbas, Silvia Guionaud, Giovanni Pellegrini, Francesco Marchesi

{"title":"Spontaneous clinical and anatomical pathology findings in SDRG rats.","authors":"Valeria Bertani, Lucia Minoli, Anna de Battisti, Alice Cantachin, Giuliano Turrini, Giulia Forcellini, Riccardo Bazzoni, Anna Slaviero, Leila Abbas, Silvia Guionaud, Giovanni Pellegrini, Francesco Marchesi","doi":"10.1177/03009858261423163","DOIUrl":"10.1177/03009858261423163","url":null,"abstract":"The SDRG rat, characterized by a Sprague-Dawley (SD) genetic background with deletion of Rag1 and Il2rg genes, has deficiencies in B, T, and natural killer (NK) cells, making it a valuable model for preclinical applications such as tissue transplantation/humanization and assessment of advanced therapeutic products. Limited data exists on spontaneous background findings in this strain, particularly in aging animals. To address this gap, this study investigated clinical and anatomical pathology findings in 83 SDRG rats (40 males and 43 females), aged 10 to 26 weeks. Analyses included hematology, clinical chemistry, bone marrow smears, blood immunophenotyping, necropsy, and histology. Hematology revealed severely reduced lymphocyte counts, with a mild age-related increase in counts. Compared with SD rats, both sexes of SDRG rats had higher neutrophil, monocyte, and eosinophil counts; increased urea and cholesterol; lower albumin and total protein; and higher age-related glutamate dehydrogenase concentrations. Males had longer prothrombin times, while females showed sporadic age-related increases in alanine aminotransferase, aspartate aminotransferase, and triglycerides. Blood immunophenotyping confirmed the absence of circulating B and T lymphocytes and NK cells, alongside increased monocytes. Salient microscopic findings included lymphoid organ hypoplasia and inflammation in kidneys and lungs, with urinary bacterial infections, contributing to a single mortality. Age-related changes included progressive cardiomyopathy, early chronic progressive nephropathy, and early reproductive senescence in females. These findings underscore the SDRG strain's potential as a model for preclinical evaluations of cell-based products and provide an initial reference into background features of this immunodeficient model that might help interpretations of experimental results.","PeriodicalId":23513,"journal":{"name":"Veterinary Pathology","volume":" ","pages":"512-527"},"PeriodicalIF":1.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147356658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pathological insights of human CD34+ hematopoietic stem cell-engrafted NSG mice: Implications for the safety assessment of cancer immunotherapy drugs. 人CD34+造血干细胞移植NSG小鼠的病理观察：癌症免疫治疗药物安全性评估的意义

IF 1.7 2区农林科学

Veterinary Pathology Pub Date : 2026-05-01 Epub Date: 2026-03-04 DOI: 10.1177/03009858261423132

Anna Maria Giusti, Johannes Sam, Sara Colombetti, Inês Berenguer Veiga, Josep M Monné Rodríguez

{"title":"Pathological insights of human CD34+ hematopoietic stem cell-engrafted NSG mice: Implications for the safety assessment of cancer immunotherapy drugs.","authors":"Anna Maria Giusti, Johannes Sam, Sara Colombetti, Inês Berenguer Veiga, Josep M Monné Rodríguez","doi":"10.1177/03009858261423132","DOIUrl":"10.1177/03009858261423132","url":null,"abstract":"Humanized mice engrafted with human CD34+ hematopoietic stem cells (HSCs) are invaluable models for the preclinical evaluation of cancer immunotherapy drugs, helping to bridge the gap between in vitro studies and clinical trials. However, there are inherent challenges associated with these models, which require careful consideration, as they can obscure the distinction between treatment-related effects and model-specific background lesions. Here, we provide a comprehensive overview of common histopathological changes in such models, focusing on humanized nonobese diabetic (NOD) Cg-Prkdcscid Il2rgtm1Wjl/SzJ (huNSG) mice engrafted with human CD34+ HSCs. We characterize engraftment kinetics and histopathological changes at various timepoints post-engraftment and provide examples of huNSG mice utilized to evaluate immuno-oncology compounds and how these drugs influenced the development of huNSG-related background lesions. Flow cytometry and immunohistochemistry analyses reveal dynamic changes in human immune cell populations, with a predominance of B cells over T cells at early timepoints, shifting to T cell predominance at later stages. Notably, spontaneous granulomatous lesions, dominated by human macrophages, are observed in multiple organs, which increase in incidence and severity over time. These lesions are exacerbated by immunostimulatory treatments, highlighting the need for careful interpretation of drug-induced effects vs model-specific background pathology. Additionally, bone marrow necrosis that resembles ischemic lesions is identified in some huNSG mice, particularly following immune stimulation. Our findings underscore the critical importance of understanding the inherent pathological changes in huNSG mice to accurately assess the safety of cancer immunotherapy drugs.","PeriodicalId":23513,"journal":{"name":"Veterinary Pathology","volume":" ","pages":"445-461"},"PeriodicalIF":1.7,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13036269/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147356628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Epibiotic green alga (Ulva spp.) on the skin of turbot (Scophthalmus maximus) with chronic aeromoniasis. 慢性肺单胞菌病的大菱鲆（Scophthalmus maximus）皮肤上的表皮绿藻（Ulva spp.）。

IF 1.7 2区农林科学

Veterinary Pathology Pub Date : 2026-04-22 DOI: 10.1177/03009858261441526

Xoel Souto, Ana P Losada, Beatriz Pardo, Iris Martín, Roberto Bermúdez, María I Quiroga

{"title":"Epibiotic green alga (Ulva spp.) on the skin of turbot (Scophthalmus maximus) with chronic aeromoniasis.","authors":"Xoel Souto, Ana P Losada, Beatriz Pardo, Iris Martín, Roberto Bermúdez, María I Quiroga","doi":"10.1177/03009858261441526","DOIUrl":"https://doi.org/10.1177/03009858261441526","url":null,"abstract":"Chronic aeromoniasis in turbot (Scophthalmus maximus), caused by Aeromonas salmonicida, provokes cutaneous lesions that occasionally expose dermal tubercles, which may act as unconventional ecological niches. A storm in February 2024 caused severe damage at a turbot farm in Galicia (Northwestern Spain), leaving various tanks uncovered and subsequently exposing fish with chronic aeromoniasis to several days of intense solar irradiation. Afterward, farm staff observed green tufts over the animals. Two affected turbots were submitted for necropsy. Morphological features identified the epibiont as the alga Ulva spp., covered by a biofilm containing A. salmonicida DNA (detected by real-time polymerase chain reaction). The algae did not trigger additional host responses beyond those induced by aeromoniasis, indicating true epibiosis rather than infection. However, algal colonization physically obstructs re-epithelialization and may prolong lesion chronicity, while the associated biofilm could serve as an environmental reservoir for the pathogen. This case illustrates how environmental disruptions can generate unexpected host-pathogen-epibiont interactions. To our knowledge, this is the first report of Ulva epibiosis on fish.","PeriodicalId":23513,"journal":{"name":"Veterinary Pathology","volume":" ","pages":"3009858261441526"},"PeriodicalIF":1.7,"publicationDate":"2026-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147782429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Corrigendum to Sudden death of a cynomolgus monkey due to transfusion-related acute lung injury (TRALI) after xeno-transfusion from a minipig. 一只食蟹猴在接受猪异种输血后因输血相关急性肺损伤（TRALI）猝死的更正。

IF 1.7 2区农林科学

Veterinary Pathology Pub Date : 2026-04-09 DOI: 10.1177/03009858261438044

引用次数: 0

Pathology and diagnosis of brucellosis (Brucella spp.) in veterinary species. 兽医种布鲁氏菌病（布鲁氏菌属）的病理学和诊断。

IF 1.7 2区农林科学

Veterinary Pathology Pub Date : 2026-04-09 DOI: 10.1177/03009858261435106

Agustín Rebollada-Merino, Lucas Domínguez, Antonio Rodríguez-Bertos

{"title":"Pathology and diagnosis of brucellosis (Brucella spp.) in veterinary species.","authors":"Agustín Rebollada-Merino, Lucas Domínguez, Antonio Rodríguez-Bertos","doi":"10.1177/03009858261435106","DOIUrl":"https://doi.org/10.1177/03009858261435106","url":null,"abstract":"Brucellosis is an infectious disease that affects a wide range of animals, caused by bacteria belonging to 13 species and several biovars within the Brucella genus (B. melitensis, B. abortus, B. suis, B. ovis, B. neotomae, B. canis, B. ceti, B. pinnipedialis, B. microti, B. inopinata, B. papionis, B. vulpis, B. nosferati, and unclassified strains). Brucella spp. infects small ruminants, cattle, swine, dogs, wild mammals, reptiles, amphibians, and fish, and most Brucella spp. have zoonotic potential. Characterization of lesions in animal brucellosis remains paramount in the diagnosis in endemic regions and even for countries free of brucellosis, where passive surveillance plays an indispensable role in upholding and sustaining their status. Pathology also contributes to understanding the pathogenesis and associating emerging pathogenic Brucella spp. with disease in animals. Here, we review the pathology of brucellosis in animals with an emphasis on cross-species transmission of \"classical\" Brucella spp. to nonpreferential hosts and \"atypical\" Brucella spp. We conclude that Brucella is an expansive genus identified in numerous animals, but there are still significant gaps in the knowledge of the pathology of brucellosis in unusual hosts and emerging Brucella spp. This is a great opportunity for veterinary pathologists to spearhead advancements in the knowledge of the pathogenesis and diagnosis of Brucella spp. infections. The isolation of a Brucella spp. and the correlation with lesions should follow molecular diagnostics to define the genetic signature of the isolate, providing a better understanding of epidemiology and contributing to the control of brucellosis across animal and human populations.","PeriodicalId":23513,"journal":{"name":"Veterinary Pathology","volume":" ","pages":"3009858261435106"},"PeriodicalIF":1.7,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147646676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comprehensive phenotypic and clonality analysis of intraepithelial lymphocytes of intestinal T-cell lymphoma and chronic enteropathy in dogs. 犬肠t细胞淋巴瘤和慢性肠病上皮内淋巴细胞的综合表型和克隆性分析。

IF 1.7 2区农林科学

Veterinary Pathology Pub Date : 2026-03-30 DOI: 10.1177/03009858261428495

Kazuhiro Kojima, James K Chambers, Ko Nakashima, Yuko Goto-Koshino, Kazuyuki Uchida

{"title":"Comprehensive phenotypic and clonality analysis of intraepithelial lymphocytes of intestinal T-cell lymphoma and chronic enteropathy in dogs.","authors":"Kazuhiro Kojima, James K Chambers, Ko Nakashima, Yuko Goto-Koshino, Kazuyuki Uchida","doi":"10.1177/03009858261428495","DOIUrl":"https://doi.org/10.1177/03009858261428495","url":null,"abstract":"Canine intestinal T-cell lymphoma (ITCL) may arise from intraepithelial lymphocyte (IEL) subsets expanded in chronic enteropathy (CE). To investigate this potential cell of origin, we performed flow cytometry, immunohistochemistry, and RNA in situ hybridization on IELs using biopsy samples from 62 dogs, including 6 large-cell lymphomas (LCLs), 9 small-cell lymphomas (SCLs), 31 CEs with increased IELs (IEL+CE), and 16 CEs without increased IELs (IEL-CE). IELs in ITCLs were predominantly CD4-CD8α- (LCL, 5/6; SCL, 4/9), and 4/31 IEL+CEs had a higher proportion of CD4-CD8α- IELs than the other CE cases. Forward scatter values of CD4-CD8α- IELs were higher in IEL+CEs compared with IEL-CEs, correlating positively with the Ki-67 index, indicating proliferation of this population. An increase in IELs lacking T-cell receptor expression was observed in 1/4 LCL, 2/5 SCL, and 1/13 IEL+CE cases. Lack of surface CD3 was observed in 2/9 SCL cases. One of 5 LCL cases partially expressed NKp46, whereas the proportion of NKp46+ IELs was low (< 4%) in 32/33 CE cases examined. In addition, 3/6 LCL cases expressed NKp46 mRNA without detectable protein expression. Clonality analysis of isolated IELs yielded at least 1 clonal peak in 1/2 LCLs, 4/7 SCLs, 12/23 IEL+CEs, and 4/13 IEL-CEs, underscoring the limited diagnostic utility on distinguishing ITCL, particularly SCL, from IEL+CE. These findings suggest that most canine ITCLs have a CD4-CD8α- immunophenotype and that unconventional IELs in IEL+CE may be the cells of origin. Moreover, the distinction between ITCL and CE remains challenging, emphasizing the importance of integrated diagnostic approaches.","PeriodicalId":23513,"journal":{"name":"Veterinary Pathology","volume":" ","pages":"3009858261428495"},"PeriodicalIF":1.7,"publicationDate":"2026-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147582125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A retrospective study of neuroschistosomiasis in aquatic birds. 水禽神经血吸虫病的回顾性研究。

IF 1.7 2区农林科学

Veterinary Pathology Pub Date : 2026-03-29 DOI: 10.1177/03009858261428494

Emi Sasaki, Amira Abdu, April L Childress, Daniel B Paulsen, James F X Wellehan, Michael M Garner

{"title":"A retrospective study of neuroschistosomiasis in aquatic birds.","authors":"Emi Sasaki, Amira Abdu, April L Childress, Daniel B Paulsen, James F X Wellehan, Michael M Garner","doi":"10.1177/03009858261428494","DOIUrl":"https://doi.org/10.1177/03009858261428494","url":null,"abstract":"Schistosomatidae is a family of trematodes that generally have an indirect life cycle, with snails as intermediate hosts in avian schistosomiasis and aquatic birds as definitive hosts. Although multiple studies report avian schistosomes, there are only a few reports describing gross and histological lesions of neuroschistosomiasis in aquatic birds. Herein, a retrospective study including 12 aquatic birds with neuroschistosomiasis was conducted to further characterize the clinical, gross, and histologic findings and to identify the trematodes. The median age of birds was 12 years, and schistosomes were observed in the brain, with or without granulomatous inflammation. Neuroschistosomiasis was likely related to death in 5 out of 12 birds. Twelve formalin-fixed paraffin-embedded (FFPE) samples containing brain, 1 FFPE sample containing intestine, and 1 fresh brain sample were used for polymerase chain reaction (PCR) and sequencing to identify the schistosomes. Dendritobilharzia pulverulenta was identified from 3 out of 13 FFPE samples and 1 fresh brain sample. Neuroschistosomiasis presumptively associated with Dendritobilharzia sp. infection has been reported in swans and geese; however, the identification was based on the clinical signs, lesions, location within the hosts, and the morphology of adult worms without molecular analysis. To the authors' knowledge, the histologic description and molecular identification of schistosomes that cause neuroschistosomiasis in multiple aquatic bird species other than swans and geese have not been reported.","PeriodicalId":23513,"journal":{"name":"Veterinary Pathology","volume":" ","pages":"3009858261428494"},"PeriodicalIF":1.7,"publicationDate":"2026-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147575466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnostic challenge in veterinary pathology: Nephropathy, gastropathy, and pericarditis in feedlot cattle. 兽医病理学中的诊断挑战：饲养场牛的肾病、胃病和心包炎。

IF 1.7 2区农林科学

Veterinary Pathology Pub Date : 2026-03-25 DOI: 10.1177/03009858261435116

Larissa L de Souza, Thabata C A de Menezes, Maria E M da Silva, Rayane C Pupin, Danilo C Gomes, Ricardo A A Lemos

引用次数: 0