Urolithiasis最新文献_第6页

Predictive value of NCCT quantitative analysis for proximal and middle impacted ureteral stones. NCCT 定量分析对输尿管近端和中段冲击性结石的预测价值。

IF 2 2区医学

Urolithiasis Pub Date : 2024-08-23 DOI: 10.1007/s00240-024-01616-w

Haiyang Wei, Xinyu Shi, Changbao Xu, Wuxue Li, Tianhe Zhang, Zhiheng Huang, Junkai Yang, Xinghua Zhao

{"title":"Predictive value of NCCT quantitative analysis for proximal and middle impacted ureteral stones.","authors":"Haiyang Wei, Xinyu Shi, Changbao Xu, Wuxue Li, Tianhe Zhang, Zhiheng Huang, Junkai Yang, Xinghua Zhao","doi":"10.1007/s00240-024-01616-w","DOIUrl":"https://doi.org/10.1007/s00240-024-01616-w","url":null,"abstract":"The purpose of the study was to explore the predictive value of preoperative quantitative NCCT analysis for proximal and middle ureteral stone impaction. Data of 128 patients who diagnosed with proximal and middle ureteral stones were analyzed. Stone size, upper diameter of the ureter(D1), lower diameter of the ureter (D2), CT attenuation of the ureter above the stone (HA, 'HU above'), CT attenuation of the ureter below the stone (HB, 'HU below'), CT attenuation values of the stone's proximal segments (C1), CT attenuation values of the stone's distal segments (C2), and ureteral wall thickness(UWT)were recorded. Logistic regression was used to perform univariate and multivariate analyses of the data to determine the independent predictors of proximal and middle ureteral stone impaction. The receiver operating characteristic (ROC) curve was plotted to evaluate the predictive performance. Among the 128 patients, 52 (40.6%) had impacted stones, while 76 (59.4%) did not. Multivariate logistic regression analysis showed that stone size > 9.45 mm (OR = 1.372, 95% CI = 1.071-1.756, P = 0.012), UWT > 3.22 mm (OR = 4.217, 95% CI = 2.165 ~ 8.213, P < 0.001)、DDR > 2.10 (OR = 4.901, 95% CI = 1.797 ~ 13.365, P = 0.002)and HBA > 1.58 (OR = 5.237,95% CI = 1.502 ~ 18.259, P = 0.009)were independent risk factors for predicting ureteral stone impaction. In conclusion, stone size, UWT, DDR, and HBA show crucial predictive value for impaction of stones.","PeriodicalId":23411,"journal":{"name":"Urolithiasis","volume":"52 1","pages":"120"},"PeriodicalIF":2.0,"publicationDate":"2024-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142037138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Changes in blood gas in supine and prone positions in percutaneous stone surgery: does position have any advantage for hemodynamics? 经皮取石手术中仰卧位和俯卧位的血气变化：体位对血流动力学有好处吗？

IF 2 2区医学

Urolithiasis Pub Date : 2024-08-23 DOI: 10.1007/s00240-024-01615-x

Yilmaz Erdal, Senocak Ibrahim, Ataman Mirac, Yuvanc Ercan

{"title":"Changes in blood gas in supine and prone positions in percutaneous stone surgery: does position have any advantage for hemodynamics?","authors":"Yilmaz Erdal, Senocak Ibrahim, Ataman Mirac, Yuvanc Ercan","doi":"10.1007/s00240-024-01615-x","DOIUrl":"10.1007/s00240-024-01615-x","url":null,"abstract":"To evaluate whether different positions are advantageous for hemodynamics and respiratory balance in patients undergoing percutaneous nephrolithotomy (PCNL) procedures. Pre- and postoperative arterial blood gas data obtained during spontaneous breathing for 67 prone (Group 1) and 56 supine (Group 2) patients undergoing PCNL were analyzed. Additionally data on all patients' gender, age, body mass index, stone size, access and surgical duration, volume of irrigation fluid, length of hospital stay, requirement for blood transfusion, and residual stones were recorded: There were no differences between the groups in terms of age, stone size, operation time, access time, radiation exposure, transfusion requirements, stone-free rate, and length of hospitalization. A statistically significant pH decrease was observed in both groups in the postoperative period (p = 0.001 and p = 0.001, respectively). There was a statistically significant increase in pCO2 values in both groups in the postoperative period (p = 0.001 and p = 0.024, respectively), and that increase did not differ significantly between the groups (p = 0.624). A statistically significant decrease in pO2 and SpO2 values was observed in both groups in the postoperative period compared to the preoperative period. Again, no statistical difference was observed between the groups for these values. There was a statistically significant decrease in bicarbonate in both groups period (p < 0.001 and p = 0.001, respectively). Hemodynamics and the respiratory balance of the patient are impaired in both prone and supine positions. Neither position is superior to the other in this respect.","PeriodicalId":23411,"journal":{"name":"Urolithiasis","volume":"52 1","pages":"121"},"PeriodicalIF":2.0,"publicationDate":"2024-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142037137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Familial aggregation of urolithiasis: findings from a Nationwide Middle Eastern study. 泌尿系结石的家族聚集性：一项全国性中东研究的结果。

IF 2 2区医学

Urolithiasis Pub Date : 2024-08-21 DOI: 10.1007/s00240-024-01618-8

Amir Hossein Kashi, Mahsa Zobeiry, Abbas Basiri, Nasrin Borumandnia, Maryam Taheri, Mazyar Zahir

{"title":"Familial aggregation of urolithiasis: findings from a Nationwide Middle Eastern study.","authors":"Amir Hossein Kashi, Mahsa Zobeiry, Abbas Basiri, Nasrin Borumandnia, Maryam Taheri, Mazyar Zahir","doi":"10.1007/s00240-024-01618-8","DOIUrl":"https://doi.org/10.1007/s00240-024-01618-8","url":null,"abstract":"This study aimed to determine the potential effect of genetic factors and positive family history on the familial aggregation of urolithiasis in Iran. Of the total 44,186 participants in the Iran National Stone Survey (INSS) database, 34,953 individuals who were members of 8629 nuclear families were included in this study. The mean prevalence of urolithiasis was 5.7% [95%CI: 5.5 - 6.0%] in this subpopulation. Familial aggregation of urolithiasis was analyzed in 34,745 participants (99.6% of those originally included) utilizing a multivariable logistic regression with second order generalized estimating equations approach (GEE2) to adjust for sex, age, urbanization status and ethnicity. Recurrence risk ratios (λ) were used to evaluate the degree of familial aggregation. Our multivariable analysis demonstrated a strong familial aggregation of urolithiasis within sibling pairs (λs = 78.35), parent-offspring pairs (λo = 40.12) and spouse pairs (λsp = 21.62). The respective ORs were 5.65 [95%CI: 3.49, 9.14] for siblings, 2.85 [95%CI: 2.20, 3.68] for parents and 1.27 [95%CI: 1.06, 1.54] for spouses. Urinary stone disease tends to aggregate in families with a positive history of urolithiasis in either the parents or siblings. Siblings have a more prominent effect in inducing familial aggregation compared to parents. Despite the prominent role of familial genetic components in urolithiasis aggregation, shared environmental factors appear to partake in this phenomenon to some extent, as suggested by urolithiasis aggregation among spouse pairs.","PeriodicalId":23411,"journal":{"name":"Urolithiasis","volume":"52 1","pages":"119"},"PeriodicalIF":2.0,"publicationDate":"2024-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142018783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Trajectories of body mass index and incident kidney stone disease: a prospective cohort study in Chinese young adults. 体重指数与肾结石发病的轨迹：一项针对中国青壮年的前瞻性队列研究。

IF 2 2区医学

Urolithiasis Pub Date : 2024-08-21 DOI: 10.1007/s00240-024-01617-9

Xujuan Zheng, Yanxia Wu, Lingling Huang, Juan Xiong

{"title":"Trajectories of body mass index and incident kidney stone disease: a prospective cohort study in Chinese young adults.","authors":"Xujuan Zheng, Yanxia Wu, Lingling Huang, Juan Xiong","doi":"10.1007/s00240-024-01617-9","DOIUrl":"10.1007/s00240-024-01617-9","url":null,"abstract":"The present study aims to explore the potential changing trajectory patterns of body mass index (BMI) for Chinese young adults and identify the relationship of BMI trajectory patterns with kidney stone disease (KSD) incidence. Latent class growth analysis was used to identify distinct trajectories of BMI during young adulthood. Cox proportion hazard models were conducted to explore the association between the BMI trajectory group memberships and incident KSD. Subgroup and sensitivity analyses were undertaken to test the robustness of the findings. In total, 2,966 young adults who attended at least three annual check-ups from 2014 to 2021 without KSD at baseline were enrolled in the cohort analysis. Three district BMI trajectories were identified for young adults, labeled as low-stable in normal BMI (28.5%), medium-rising to high BMI (67.4%), and rapid-rising to high BMI (4.1%). Compared with the low-stable in normal BMI group, Hazard ratios (HRs) of the rapid-rising and medium-rising to high BMI groups were 3.19 (95% CI: 1.54-6.63) and 1.78 (95% CI: 1.08-2.92) after adjusting the covariates. The cumulative incidence curves likewise illustrated that young adults in the rapid-rising to high BMI group had the highest risk of developing KSD compared to the other two groups. The rapid BMI growth trajectories during young adulthood were identified to be independently associated with a higher risk of KSD. The findings supplied novel insights that monitoring the BMI changing pattern may be favorable to early intervention of KSD during young adulthood.","PeriodicalId":23411,"journal":{"name":"Urolithiasis","volume":"52 1","pages":"118"},"PeriodicalIF":2.0,"publicationDate":"2024-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142018784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mitochondrial dysfunction in kidney stones and relief of kidney stones after reducing mtROS. 肾结石中的线粒体功能障碍和减少 mtROS 后肾结石的缓解。

IF 2 2区医学

Urolithiasis Pub Date : 2024-08-13 DOI: 10.1007/s00240-024-01614-y

Yuexian Xu, Guoxiang Li, Defeng Ge, Yan Chen, Bingbing Hou, Zongyao Hao

{"title":"Mitochondrial dysfunction in kidney stones and relief of kidney stones after reducing mtROS.","authors":"Yuexian Xu, Guoxiang Li, Defeng Ge, Yan Chen, Bingbing Hou, Zongyao Hao","doi":"10.1007/s00240-024-01614-y","DOIUrl":"https://doi.org/10.1007/s00240-024-01614-y","url":null,"abstract":"Mitochondria are essential organelles because they generate the energy required for cellular functions. Kidney stones, as one of the most common urological diseases, have garnered significant attention. In this study, we first collected peripheral venous blood from patients with kidney stones and used qRT-PCR to detect mitochondrial DNA (mtDNA) copy number as a means of assessing mitochondrial function in these patients. Subsequently, through Western blotting, qPCR, immunofluorescence, immunohistochemistry, and transmission electron microscopy, we examined whether calcium oxalate crystals could cause mitochondrial dysfunction in the kidney in both in vitro and in vivo. We then examined the intersection of the DEGs obtained by transcriptome sequencing of the mouse kidney stone model with mitochondria-related genes, and performed KEGG and GO analyses on the intersecting genes. Finally, we administered the mitochondrial ROS scavenger Mito-Tempo in vivo and observed its effects. Our findings revealed that patients with kidney stones had a reduced mtDNA copy number in their peripheral venous blood compared to the control group, suggesting mitochondrial dysfunction in this population. This conclusion was further validated through in vitro and in vivo experiments. Enrichment analyses revealed that the intersecting genes were closely related to metabolism. We observed that after mitochondrial function was preserved, the deposition of calcium oxalate crystals decreased, and the kidney damage and inflammation caused by them were also alleviated. Our research indicates that kidney stones can cause mitochondrial dysfunction. After clearing mtROS, the damage and inflammation caused by kidney stones are reversed, providing new insights into the prevention and treatment of kidney stones.","PeriodicalId":23411,"journal":{"name":"Urolithiasis","volume":"52 1","pages":"117"},"PeriodicalIF":2.0,"publicationDate":"2024-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141971944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fabrication of acoustically and physically validated artificial stones to natural kidney stones under shock waves and laser lithotripsy. 在冲击波和激光碎石作用下，制造出经过声学和物理学验证的人工结石与天然肾结石。

IF 2 2区医学

Urolithiasis Pub Date : 2024-08-12 DOI: 10.1007/s00240-024-01613-z

Hyeji Park, Sang Won So, Christine Joy G Castillo, Majed M Alharthi, Mohammad Mesadef A Zogan, Sung Yong Cho

{"title":"Fabrication of acoustically and physically validated artificial stones to natural kidney stones under shock waves and laser lithotripsy.","authors":"Hyeji Park, Sang Won So, Christine Joy G Castillo, Majed M Alharthi, Mohammad Mesadef A Zogan, Sung Yong Cho","doi":"10.1007/s00240-024-01613-z","DOIUrl":"10.1007/s00240-024-01613-z","url":null,"abstract":"To present an efficient method for fabricating artificial kidney stones with acoustic and physical properties to assess their fragmentation efficiency under shock waves and laser lithotripsy for very hard stones. The mixture ratio of super-hard plaster and water was adjusted to produce artificial kidney stones for comparison with > 95% human genuine calcium oxalate monohydrate (COM) and uric acid (UA) stones. Acoustic and physical properties, such as wave speed, stone hardness, density, compressive strength, and stone-free rates under shock-wave and laser lithotripsy, were assessed. The longitudinal wave speed of artificial stones prepared at a plaster-to-water ratio of 15:3 closely matched that of COM stones. Similarly, the transverse wave speed of artificial stones prepared at a plaster-to-water ratio of 15:3 to 15:5 aligned with that of COM stones. Stone fragmentation using shock-wave of artificial stones with mixed ratios ranging from 15:3 to 15:5 resembled that of COM stones. The Vickers hardness was similar to that of artificial stones produced with a mixing ratio of 15:3, similar to that of COM stones, while that of artificial stones produced with a mixing ratio of 15:5 was similar to that of UA stones. Density-wise, artificial stones with mixing ratios of 15:4 and 15:5 resembled COM stones. Compressive strength test results did not confirm the similarity between natural and artificial stones. The stone fragmentation using laser showed that stones produced with higher moisture content at a mixing ratio of 15:6 were similar to COM stones. This novel method for fabricating artificial kidney stones could be used to provide reliable materials for lithotripsy research.","PeriodicalId":23411,"journal":{"name":"Urolithiasis","volume":"52 1","pages":"116"},"PeriodicalIF":2.0,"publicationDate":"2024-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11319375/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141917547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Species-level characterization of gut microbiota and their metabolic role in kidney stone formation using full-length 16S rRNA sequencing. 利用全长 16S rRNA 测序分析肠道微生物群的物种特征及其在肾结石形成过程中的代谢作用。

IF 2 2区医学

Urolithiasis Pub Date : 2024-08-10 DOI: 10.1007/s00240-024-01610-2

Bashir Hussain, Chin-Chia Wu, Hsin-Chi Tsai, Jung-Sheng Chen, Aslia Asif, Ming-Chin Cheng, Yeong-Chin Jou, Bing-Mu Hsu

{"title":"Species-level characterization of gut microbiota and their metabolic role in kidney stone formation using full-length 16S rRNA sequencing.","authors":"Bashir Hussain, Chin-Chia Wu, Hsin-Chi Tsai, Jung-Sheng Chen, Aslia Asif, Ming-Chin Cheng, Yeong-Chin Jou, Bing-Mu Hsu","doi":"10.1007/s00240-024-01610-2","DOIUrl":"10.1007/s00240-024-01610-2","url":null,"abstract":"The critical role of the human gut microbiota in kidney stone formation remains largely unknown, due to the low taxonomic resolution of previous sequencing technologies. Therefore, this study aimed to explore the gut microbiota using high-throughput sequencing to provide valuable insights and identify potential bacterial species and metabolite roles involved in kidney stone formation. The overall gut bacterial community and its potential functions in healthy participants and patients were examined using PacBio sequencing targeting the full-length 16S rRNA gene, coupled with stone and statistical analyses. Most kidney stones comprised calcium oxalate and calcium phosphate (75%), pure calcium oxalate (20%), and calcium phosphate and magnesium phosphate (5%), with higher content of Ca (130,510.5 ± 108,362.7 ppm) followed by P (18,746.4 ± 23,341.2 ppm). The microbial community structure was found to be weaker in patients' kidney stone samples, followed by patients' stool samples, than in healthy participants' stool samples. The most abundant bacterial species in kidney stone samples was uncultured Morganella, whereas that in patient and healthy participant stool samples was Bacteroides vulgatus. Similarly, Akkermansia muciniphila was significantly enriched in patient stool samples at the species level, whereas Bacteroides plebeius was significantly enriched in kidney stone samples than that in healthy participant stool samples. Three microbial metabolic pathways, TCA cycle, fatty acid oxidation, and urea cycle, were significantly enriched in kidney stone patients compared to healthy participants. Inferring bacteria at the species level revealed key players in kidney stone formation, enhancing the clinical relevance of gut microbiota.","PeriodicalId":23411,"journal":{"name":"Urolithiasis","volume":"52 1","pages":"115"},"PeriodicalIF":2.0,"publicationDate":"2024-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141914124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Knockdown of long non-coding RNA SBF2-AS1 inhibits calcium oxalate-induced HK-2 cell injury by regulating the miR-302e/NLRP3 pathway. 敲除长非编码 RNA SBF2-AS1 通过调节 miR-302e/NLRP3 通路抑制草酸钙诱导的 HK-2 细胞损伤

IF 2 2区医学

Urolithiasis Pub Date : 2024-08-06 DOI: 10.1007/s00240-024-01606-y

Hanliang Zhu, Yiwen Chen, Yuantang Zhong, Xiangwei Xie, Xiangjian Zeng, Wangdong Deng

{"title":"Knockdown of long non-coding RNA SBF2-AS1 inhibits calcium oxalate-induced HK-2 cell injury by regulating the miR-302e/NLRP3 pathway.","authors":"Hanliang Zhu, Yiwen Chen, Yuantang Zhong, Xiangwei Xie, Xiangjian Zeng, Wangdong Deng","doi":"10.1007/s00240-024-01606-y","DOIUrl":"10.1007/s00240-024-01606-y","url":null,"abstract":"Long non-coding ribose nucleic acids (lncRNAs) have been implicated in the development of nephrolithiasis. The study aims to investigate the interplay of lncRNA SBF2-AS1 (SETbinding factor 2 antisense RNA 1) and NLR family pyrin domain containing 3 (NLRP3) in regulating the calcium oxalate monohydrate (COM)-induced human kidney HK-2 cell injury. HK-2 cells were treated with COM (100 µg/mL) to create a cellular model of kidney injury. Gene and protein expression was assessed by quantitative reverse-transcriptase polymerase chain reaction (qRT-PCR) and Western blot. Proliferation and apoptosis rates, as well as levels of malondialdehyde (MDA), lactate dehydrogenase (LDH), superoxide dismutase (SOD), tumor necrosis factor (TNF)-α, interleukin (IL)-1β, and IL-6 were measured. Additionally, potential miRNAs interacting with SBF2-AS1 and NLRP3 were predicted utilizing the starBase and TargetScan databases. The interference of SBF2-AS1 resulted in increased cell proliferation and SOD levels in HK-2 cells after COM induction. SBF2-AS1 silencing also reduced COM-induced cell death and inflammatory cytokine production by down-regulating NLRP3 protein expression. Conversely, forced upregulation of NLRP3 abrogated the effect of SBF2-AS1 interference. Notably, SBF2-AS1 interference on COM-induced oxidative stress and COM-induced cellular damage was rescued by antioxidant, indicating the involvement of oxidative burden in COM-induced damage. miR-302e acted as a mediator miRNA linking the functional association of SBF2-AS1 and NLRP3. Silencing SBF2-AS1 promoted miR-302e level and miR-302e reduced NLRP3 expression in HK-2 cells to protect against COM-induced damage. In summary, these findings suggest that downregulation of lncRNA SBF2-AS1 can potentially protect HK-2 cells from COM-induced injury by modulating the miR-302e/NLRP3 pathway.","PeriodicalId":23411,"journal":{"name":"Urolithiasis","volume":"52 1","pages":"113"},"PeriodicalIF":2.0,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141894418","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application of 11/13Fr suctioning ureteral access sheath and 8.55Fr single-use digital flexible ureteroscope in one-stage flexible ureteroscopic lithotripsy: an initial experience of 900 cases. 11/13Fr 抽吸式输尿管通路鞘和 8.55Fr 一次性数字柔性输尿管镜在一段式柔性输尿管镜碎石术中的应用：900 例病例的初步经验。

IF 2 2区医学

Urolithiasis Pub Date : 2024-08-06 DOI: 10.1007/s00240-024-01607-x

Wei-Na Huang, Hui-Long Huang, Yi-He Wang, Wei-Xuan Chen, Huan Deng, Ming-Zhu Zhong

{"title":"Application of 11/13Fr suctioning ureteral access sheath and 8.55Fr single-use digital flexible ureteroscope in one-stage flexible ureteroscopic lithotripsy: an initial experience of 900 cases.","authors":"Wei-Na Huang, Hui-Long Huang, Yi-He Wang, Wei-Xuan Chen, Huan Deng, Ming-Zhu Zhong","doi":"10.1007/s00240-024-01607-x","DOIUrl":"https://doi.org/10.1007/s00240-024-01607-x","url":null,"abstract":"Objectives: To report our initial experience of one-stage flexible ureteroscopic lithotripsy(FURL) with 11/13Fr suctioning ureteral access sheath(UAS) and 8.55Fr single-use digital flexible ureteroscope(SDFU) in upper ureteral or renal calculi.Materials and methods: We retrospectively collected the clinical data of 900 adult patients with upper ureteral or renal calculi treated by FURL with 11/13Fr suctioning UAS and 8.55Fr SDFU from January 2022 to April 2024. Demographics, peri- and postoperative outcomes were assessed.Results: In all, 40 of 940 cases(4.26%) failed to introduce UAS and required second-stage FURL because of ureterostenosis and were excluded. Mean stones size of the remaining 900 eligible cases was 1.68 ± 0.58 cm in greatest diameter. There were 228 cases of upper ureteral stone, 456 cases of renal stone and 216 cases of concomitant ureteral and renal calculi. The mean operation time was 52.20 ± 20.21 min and the postoperative hospital stay was 2.87 ± 1.37 days. The stone-free rate of 1 month postoperatively was 89.56% and only 2.44% of patients with residue underwent additional reoperation. The rate of postoperative fever, postoperative pain needing analgesic and slight ureteral mucosal injury were 5.11%, 8.22% and 7.78%, respectively. None of patient suffered from severe complications, such as sepsis or ureteral perforation.Conclusion: It's practical and suitable for the vast majority of adult patients to undergo FURL in single session with 11/13Fr suctioning UAS without preoperative stenting. FURL with 11/13Fr suctioning UAS and 8.55Fr SDFU is feasible, reliable, safe, and efficient in the management of renal stone and upper ureteral stone.","PeriodicalId":23411,"journal":{"name":"Urolithiasis","volume":"52 1","pages":"112"},"PeriodicalIF":2.0,"publicationDate":"2024-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141894417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Which surgical method is the most efficient and safest for treating coraliform kidney stones utilizing the current technology? 利用现有技术治疗珊瑚状肾结石，哪种手术方法最有效、最安全？

IF 2 2区医学

Urolithiasis Pub Date : 2024-08-06 DOI: 10.1007/s00240-024-01605-z

Akif Erbin, Feyzi Sinan Erdal, Halil Lutfi Canat

引用次数: 0