Urolithiasis最新文献

Authors' reply to: commentary on "assessment of a novel bendable-tip ureteral access sheath with integrated suction: an in vitro study". 作者回复：评论“评估一种新型可弯曲尖端输尿管导管鞘与综合吸引：一项体外研究”。

IF 2.2 2区医学

Urolithiasis Pub Date : 2025-07-30 DOI: 10.1007/s00240-025-01819-9

Mario Basulto-Martínez, John Denstedt

引用次数: 0

Improved control of renal pelvis pressure using a prototype fluid management system incorporating ureteroscope pressure feedback. 利用结合输尿管镜压力反馈的原型液体管理系统改善肾盂压力控制。

IF 2.2 2区医学

Urolithiasis Pub Date : 2025-07-30 DOI: 10.1007/s00240-025-01815-z

Leilane Glienke, Anthony F Bonzagni, Timothy L Hall, Khurshid R Ghani, William W Roberts

{"title":"Improved control of renal pelvis pressure using a prototype fluid management system incorporating ureteroscope pressure feedback.","authors":"Leilane Glienke, Anthony F Bonzagni, Timothy L Hall, Khurshid R Ghani, William W Roberts","doi":"10.1007/s00240-025-01815-z","DOIUrl":"https://doi.org/10.1007/s00240-025-01815-z","url":null,"abstract":"During ureteroscopy it is desirable to maintain renal pelvis pressure (PRP) below 40 cmH2O - the threshold for pyelovenous backflow - to decrease risk of infectious complications and postoperative pain. We sought to characterize PRP in a silicone kidney ureter model when using a prototype fluid management system (pFMS) that adjusts flowrate based on pressure feedback. These results were compared to conventional pressurized irrigation at five outflow resistance (ROUT) values. A LithoVue™ Elite ureteroscope was inserted into a silicone kidney ureter model with its tip in the renal pelvis. Irrigation was delivered from the pFMS with pressure limiter set to 40 cmH2O or from conventional pressurized irrigation at 50, 75, 100, 125, or 150 cmH2O. With pFMS irrigation, mean PRP remained below 40 cmH2O as ROUT was incremented from 0.9 to 4.9 cmH2O/(ml/min) respectively. With conventional pressurized irrigation, mean PRP increased as irrigation pressure increased and as ROUT increased. For example, when ROUT was 2.0 cmH2O/(ml/min), mean PRP was 37 cmH2O with both 125 cmH2O conventional irrigation pressure and pFMS. However, with higher ROUT values of 2.9, 4.0, and 4.9 cmH2O/(ml/min), mean PRP increased to 47, 57, and 60 cmH2O respectively with 125 cmH2O conventional irrigation pressure but was maintained below 40 cmH2O with the pFMS. Automated adjustment of irrigation based on pressure feedback is an effective way to control PRP and may reduce risk of infectious complications and postoperative pain.","PeriodicalId":23411,"journal":{"name":"Urolithiasis","volume":"53 1","pages":"147"},"PeriodicalIF":2.2,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144745141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Commentary on "Does suction in mini PCNL mitigate rise in intrarenal pressure? a prospective randomised study". 关于“迷你PCNL吸痰是否能缓解肾内压升高？”一项前瞻性随机研究。

IF 2.2 2区医学

Urolithiasis Pub Date : 2025-07-30 DOI: 10.1007/s00240-025-01822-0

Man Li, Shiyue Wu, Yibo He

引用次数: 0

To investigate the effects of surgical position on intrarenal pressure and intrarenal temperature during retrograde intrarenal flexible ureteroscopic lithotripsy: an in vitro model. 目的探讨手术体位对逆行肾内输尿管镜碎石术中肾内压力和温度的影响。

IF 2.2 2区医学

Urolithiasis Pub Date : 2025-07-28 DOI: 10.1007/s00240-025-01817-x

Jiaxing Zhang, Liangliang Dai, Jiashun Xu, Rijin Song, Xianghu Meng, Honglei Shi

{"title":"To investigate the effects of surgical position on intrarenal pressure and intrarenal temperature during retrograde intrarenal flexible ureteroscopic lithotripsy: an in vitro model.","authors":"Jiaxing Zhang, Liangliang Dai, Jiashun Xu, Rijin Song, Xianghu Meng, Honglei Shi","doi":"10.1007/s00240-025-01817-x","DOIUrl":"10.1007/s00240-025-01817-x","url":null,"abstract":"To investigate the changes in intrarenal pressure (IRP) and intrarenal temperature (IRT) in different surgical positions during retrograde intrarenal flexible ureteroscopic lithotripsy (RIRS) using a newly developed in vitro kidney model. Changes in IRP and IRT were tested in the conventional lithotomy position (CLP), the Trendelenburg position(TP), the Galdakao-modified supine Valdivia (GMSV) position, and the prone split-leg (PSL) position. Irrigation flow rates (FRs) of 0, 10, 20 and 30 ml/min were selected. The irrigation pressures (IPs) were 50, 100, 150, 200, 250, 300, 350 and 400 mmHg. IRP and IRT were recorded using an in vitro model under different surgical positions and combinations of FR and IP. The group with the highest IRT was the combination of TP and 0 ml/min, and the mean temperature reached 42.0 ℃. The group with the lowest IRT group was subject to the combination of PSL and 30 ml/min, and the mean temperature reached 38.0 ℃. Under the same IP, the IRP significantly differed across different surgical positions (P < 0.01). The IRP of PSL was always higher than those of the other three positions, whereas the IRP of GMSV was always lower than those of the other positions. When the IP was 400 mmHg, the pressure measured in the PSL position was 42.4 cmH2O. The mean intrarenal temperature is greater in the TP, whereas the mean intrarenal pressure is greater in the PSL. When urologists choose the above two positions during surgery, they need to pay more attention to the intrarenal temperature and intrarenal pressure to reduce intraoperative injury to patients and postoperative complications.","PeriodicalId":23411,"journal":{"name":"Urolithiasis","volume":"53 1","pages":"145"},"PeriodicalIF":2.2,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12304029/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Methodological considerations and technical limitations in the evaluation of ESWL success using SWE. 使用SWE评估ESWL成功的方法考虑和技术限制。

IF 2.2 2区医学

Urolithiasis Pub Date : 2025-07-28 DOI: 10.1007/s00240-025-01813-1

Enes Gurun, Mesut Ozturk, Mustafa Basaran

引用次数: 0

Gut Microbiota-Derived butyric acid attenuates kidney stone formation in humans and mice. 肠道微生物来源的丁酸可减轻人和小鼠肾结石的形成。

IF 2.2 2区医学

Urolithiasis Pub Date : 2025-07-28 DOI: 10.1007/s00240-025-01812-2

Masahiko Isogai, Shuzo Hamamoto, Rei Unno, Kazumi Taguchi, Atsushi Okada, Takahiro Yasui

{"title":"Gut Microbiota-Derived butyric acid attenuates kidney stone formation in humans and mice.","authors":"Masahiko Isogai, Shuzo Hamamoto, Rei Unno, Kazumi Taguchi, Atsushi Okada, Takahiro Yasui","doi":"10.1007/s00240-025-01812-2","DOIUrl":"10.1007/s00240-025-01812-2","url":null,"abstract":"Metabolic syndromes, particularly obesity, are associated with kidney stone formation (KSF). The gut microbiota and its metabolites, including butyrate, play critical roles in regulating inflammation and obesity-related disorders. In this study, using human tissue samples and in vivo mice experiments, we examined the effects of butyrate on KSF. We compared the gut microbiota of healthy individuals and patients with kidney stones, using 16 S rRNA gene sequencing. For in vivo analysis, five-week-old male C57BL/6J mice were administered butyric acid-supplemented water for 12 weeks, followed by intraperitoneal injection of glyoxylate (80 mg/kg) for 6 days to induce renal crystal formation (RCF). Patients with kidney stones exhibited reduced gut microbiota diversity (P = 0.037) and a lower abundance of butyrate-producing bacteria (P = 0.023) compared to healthy controls, although no significant differences were observed in the proportions of individual bacterial species. In mice, butyric acid administration significantly reduced RCF (P < 0.001). Moreover, butyric acid treatment attenuated inflammation, as evidenced by decreased expression of interleukin (Il)6 and C-C motif ligand 2 (Ccl2). The liver X receptor/retinoid X receptor (LXR/RXR) pathway was activated, as revealed by quantitative real-time polymerase chain reaction and RNA sequencing. Additionally, western blotting and transmission electron microscopy showed that butyric acid mitigated early mitochondrial and microvillar damage. In conclusion butyric acid protects against RCF by reducing inflammation and oxidative stress. This is the first report to elucidate the potential therapeutic role of butyrate, a gut microbiota-derived metabolite, based on both human and in vivo evidence.","PeriodicalId":23411,"journal":{"name":"Urolithiasis","volume":"53 1","pages":"146"},"PeriodicalIF":2.2,"publicationDate":"2025-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of minimally invasive suction-evacuation versus standard nephrostomy sheaths for the treatment of partial staghorn stones. 微创吸排术与标准肾造口术治疗部分鹿角结石的比较。

IF 2 2区医学

Urolithiasis Pub Date : 2025-07-24 DOI: 10.1007/s00240-025-01807-z

Jian Liang, Jingwei He, Hansheng Lin, Nengzhuo Feng, Wenchao Qin, Yumin Zhuo

{"title":"Comparison of minimally invasive suction-evacuation versus standard nephrostomy sheaths for the treatment of partial staghorn stones.","authors":"Jian Liang, Jingwei He, Hansheng Lin, Nengzhuo Feng, Wenchao Qin, Yumin Zhuo","doi":"10.1007/s00240-025-01807-z","DOIUrl":"10.1007/s00240-025-01807-z","url":null,"abstract":"We conducted a prospective, randomized study to compare the safety and efficacy of using a conventional nephrostomy sheath (CNS) versus a minimally invasive suction-evacuation nephrostomy sheath (SENS) for treating partial staghorn stones. Eighty-six patients with partial staghorn stones were randomly assigned into two groups, with 43 patients in each group. One group underwent standard percutaneous nephrolithotomy (sPCNL) using CNS, whereas the other group underwent minimally invasive percutaneous nephrolithotomy (mPCNL) with SENS. Patient demographics, stone characteristics, intraoperative data, perioperative data, and surgical results were collected and analyzed.The patient demographics and stone characteristics were similar in both groups. The SENS group had significantly lower peak and mean intrarenal pressure (IRP) during the procedure. The stone-free rate (SFR) was comparable between groups. The SENS group removed stones more efficiently, with shorter treatment time and less frequent use of the stone extractor. Lower IRP and shorter treatment time led to fewer postoperative complications.mPCNL with SENS results in lower IRP, faster stone removal, and reduced use of stone forceps while preserving SFR and safety.","PeriodicalId":23411,"journal":{"name":"Urolithiasis","volume":"53 1","pages":"143"},"PeriodicalIF":2.0,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144699608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tri-layer ureteral stents, with anti-encrustation surface, offer improved comfort: results from an international stent registry. 三层输尿管支架，具有抗结痂表面，提供更好的舒适性：来自国际支架注册的结果。

IF 2 2区医学

Urolithiasis Pub Date : 2025-07-23 DOI: 10.1007/s00240-025-01774-5

Runhan Ren, K F Victor Wong, Connor M Forbes, Yuanyuan Ji, Alexander P Glaser, Ryan F Paterson, Kazumi Taguchi, Ojas Shah, Edouard Tariel, Channa Amarasekera, Shuzo Hamamoto, Dirk Lange, Wilson R Molina, John J Knoedler, Amy E Krambeck, Marcelino E Rivera, Karen L Stern, Mitchell R Humphreys, Ben H Chew

{"title":"Tri-layer ureteral stents, with anti-encrustation surface, offer improved comfort: results from an international stent registry.","authors":"Runhan Ren, K F Victor Wong, Connor M Forbes, Yuanyuan Ji, Alexander P Glaser, Ryan F Paterson, Kazumi Taguchi, Ojas Shah, Edouard Tariel, Channa Amarasekera, Shuzo Hamamoto, Dirk Lange, Wilson R Molina, John J Knoedler, Amy E Krambeck, Marcelino E Rivera, Karen L Stern, Mitchell R Humphreys, Ben H Chew","doi":"10.1007/s00240-025-01774-5","DOIUrl":"https://doi.org/10.1007/s00240-025-01774-5","url":null,"abstract":"A tri-layer ureteral stent with novel coating lining the inner and outer surfaces (Tria™) was designed to reduce encrustation. We assessed technical success, complications, and patient symptoms in an international prospective stent registry conducted from 2020 to 2023. Outcomes included technical success, infections, and encrustation rates. Patient-reported PROMIS Pain Intensity (3a) and Pain Interference (6b) scores were obtained at time of index procedure, stent removal, and post-stent removal. Tria stents were compared to non-Tria stents grouped together. Of 359 total patients, 271 had a unilateral stent placed for stone management procedures. Tria vs. non-Tria groups were comparable in age (55.9y vs. 58.7y), gender (57.8% vs. 56.4% male), BMI (28.9 vs. 29.7 kg/m2), and stent indwell times (11.8 vs. 9.9 days). Pain interference scores (p = 0.025) were lower in patients with Tria stents, and pain intensity scores approached significance (p = 0.052). Non-Tria patients reported significantly larger decreases from the week prior to stent removal to post-stent removal in both domains (p = 0.0245, p = 0.0216). Infection (Tria 1.9% vs. non-Tria 3.4%, p = 0.45) and encrustation rates (Tria 1.3% vs. non-Tria 0%, p = 0.36) were both low and non-significantly different. Patients with Tria stents were more comfortable than non-Tria stents in the week prior to stent removal and post-stent removal visits.","PeriodicalId":23411,"journal":{"name":"Urolithiasis","volume":"53 1","pages":"142"},"PeriodicalIF":2.0,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144691664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comments on the "Does suction in Mini PCNL mitigate rise in intrarenal pressure?" 关于“Mini PCNL抽吸是否能缓解肾内压升高？”的评论

IF 2 2区医学

Urolithiasis Pub Date : 2025-07-22 DOI: 10.1007/s00240-025-01814-0

Yinying Chai, Yibo He, Shengliang Qiu

引用次数: 0

The Gut-Kidney Axis in urolithiasis: extending Microbiome research beyond correlation to mechanism. 尿石症的肠肾轴：将微生物组研究扩展到机制之外。

IF 2 2区医学

Urolithiasis Pub Date : 2025-07-21 DOI: 10.1007/s00240-025-01811-3

Yuxuan Song, Jingyi Chen, Yun Peng, Ning Chen, Tao Xu

引用次数: 0