Manuel Parra Collado , Paula Gandía Ureña , Eva Gavela Martínez , Julia Kanter Berga , Cristina Castro Alonso , Emma Calatayud Aristoy , Aina Quilis Pellicer , Sandra Beltrán Catalán , Belén Vizcaíno Castillo , Asunción Sancho Calabuig
{"title":"Graft Intolerance Syndrome Complicates Retransplantation","authors":"Manuel Parra Collado , Paula Gandía Ureña , Eva Gavela Martínez , Julia Kanter Berga , Cristina Castro Alonso , Emma Calatayud Aristoy , Aina Quilis Pellicer , Sandra Beltrán Catalán , Belén Vizcaíno Castillo , Asunción Sancho Calabuig","doi":"10.1016/j.transproceed.2024.11.027","DOIUrl":"10.1016/j.transproceed.2024.11.027","url":null,"abstract":"<div><h3>Background</h3><div>Patients with non-functioning renal grafts constitute approximately 4% of patients with incident dialysis. Complete withdrawal of immunosuppression has been associated with a higher risk of HLA sensitization and renal graft intolerance syndrome (GIS).</div></div><div><h3>Methods</h3><div>We conducted a retrospective observational study of 63 patients with renal graft failure (from January 2012 to December 2022). Immediate graft losses due to vascular thrombosis or technical complications were excluded. We analyzed demographic and clinical characteristics, as well as the evolution of GIS. A comparative study was performed with patients who did not develop GIS (non-GIS).</div></div><div><h3>Results</h3><div>Twenty-three patients (36.5%) developed GIS. The most common presentation was anemia (73.9%), followed by renal graft pain (65.2%). Seventeen patients (74%) required renal graft embolization. GIS was associated with a higher degree of sensitization. We did not find differences in prior HLA sensitization, causes of graft failure, history of acute rejection, or doses/levels of immunosuppression after graft failure, although rejections were more severe in the GIS group. Patients with GIS had a lower rate of retransplantation after graft failure (4.3% vs 25%, <em>P</em> = .02). Graft failure within the first 2 years after transplantation was the main predictive factor for GIS (hazard ratio = 2.740, 95% confidence interval = 1.06–7.06, <em>P</em> = .03).</div></div><div><h3>Conclusions</h3><div>GIS was more prevalent in patients who experienced graft failure within the first 2 years. Despite increased immunosuppression, a significant percentage required graft embolization. GIS was associated with an increase in HLA sensitization and a lower likelihood of retransplantation.</div></div>","PeriodicalId":23246,"journal":{"name":"Transplantation proceedings","volume":"57 1","pages":"Pages 30-32"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142928960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
María Araceli Povedano Medina , Álvaro Arnau Prieto , Aitor Parra Zurutuza , Cristina Martínez Amunarriz , María Jesús Bustinduy Odriozola , Xabier Camino Ortiz de Barrón , Esther Pérez Santaolalla , Olga Maíz Alonso , Iasone Benavente Claveras , María Teresa Rodrigo de Tomas
{"title":"Hemophagocytic Lymphohistiocytosis in a Kidney Transplant Recipient: Case Report","authors":"María Araceli Povedano Medina , Álvaro Arnau Prieto , Aitor Parra Zurutuza , Cristina Martínez Amunarriz , María Jesús Bustinduy Odriozola , Xabier Camino Ortiz de Barrón , Esther Pérez Santaolalla , Olga Maíz Alonso , Iasone Benavente Claveras , María Teresa Rodrigo de Tomas","doi":"10.1016/j.transproceed.2024.12.012","DOIUrl":"10.1016/j.transproceed.2024.12.012","url":null,"abstract":"<div><div>Hemophagocytic lymphohistiocytosis is a potentially fatal multisystemic inflammatory syndrome that is better understood in the pediatric population. Consequently, the diagnostic criteria for adults still derives from studies conducted in the pediatric population. Several genetic mutations and secondary causes, including infections, autoimmunity, and malignancy, have been reported as significant actors in this condition, especially in adults. It is of the utmost importance to identify these triggers, as the treatment of this condition is largely dependent on addressing the underlying cause. Those who have undergone transplantation and whose immune response is already compromised are particularly susceptible to this condition. We present the case of a 74-year-old kidney transplant recipient who was admitted due to a persistent fever of unknown origin, pancytopenia, and splenomegaly. The patient was ultimately diagnosed with hemophagocytic lymphohistiocytosis in our hospital secondary to Epstein–Barr virus, aspergillosis, and leishmania infections. Targeted treatments for the aforementioned conditions led to the resolution of the syndrome and the recovery of the patient. Lymphohistiocytosis is a rare, albeit serious, condition that should be considered a differential diagnosis in the early stages of critical illness in transplant recipient patients. Doing so enables target treatments to be administered as soon as possible.</div></div>","PeriodicalId":23246,"journal":{"name":"Transplantation proceedings","volume":"57 1","pages":"Pages 90-92"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142928961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrea Severo , Javier González Martín , Cristina Mateo Gómez , Josefina Arias Mahiques , Alexia Denisse Aguzezko , María Eugenia Tanaro , Ruth Echeverría , Javier de Juan Bagudá , Christian Muñoz Guijosa , Francisco López Medrano , Juan Delgado , María Dolores García-Cosío Carmena
{"title":"High-risk Cytomegalovirus in Heart Transplant: How Can We Improve?","authors":"Andrea Severo , Javier González Martín , Cristina Mateo Gómez , Josefina Arias Mahiques , Alexia Denisse Aguzezko , María Eugenia Tanaro , Ruth Echeverría , Javier de Juan Bagudá , Christian Muñoz Guijosa , Francisco López Medrano , Juan Delgado , María Dolores García-Cosío Carmena","doi":"10.1016/j.transproceed.2024.11.024","DOIUrl":"10.1016/j.transproceed.2024.11.024","url":null,"abstract":"<div><h3>Background</h3><div>Cytomegalovirus (CMV) infection is associated with worse outcomes after heart transplant (HT). CMV mismatch (donor positive, recipient negative serology, D+/R-) increases the risk of infection. Guidelines recommend 3 to 6 months of antiviral prophylaxis in these patients. An increase in primary CMV infections at our center prompted us to analyses this population in search of improvement.</div></div><div><h3>Methods</h3><div>From 185 adult HT receptors in 10 years, we selected those with CMV D+/R-. Patients were followed until October 2023. We evaluated the patterns of transmission of CMV in accordance with current recommendations.</div></div><div><h3>Results</h3><div>We assessed 35 HT recipients with CMV mismatch (median age of 48.8 ± 13.8 years, 71% men). Median follow-up was 5.5 years [1.9-7.4]. Median duration of CMV prophylaxis was 3.7 (±2.1) months post-HT. CMV infection occurred in 74% of patients (96% within the first 6 months after ending prophylaxis) and CMV disease in 26%. Half of them required hospital admission. One third had concomitant infections by other microorganisms. There were no significant differences in the duration of prophylaxis between patients with and without CMV infection. Survival on follow-up was 77%. 2 patients died during CMV infection due to other infection.</div></div><div><h3>Conclusions</h3><div>CMV infection rate in D+/R- HT receptors remains high even after the prophylactic period recommended by current guidelines. A better knowledge of CMV-transmitted infection, coupled with the pursuit of a suitable equilibrium between the prevention of infection and rejection, have the potential to enhance the outcomes of this high-risk population through tailored protocols.</div></div>","PeriodicalId":23246,"journal":{"name":"Transplantation proceedings","volume":"57 1","pages":"Pages 67-69"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142928962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alba María Fernández González , Ninoska Moreira Lorenzo , Benito Cantador Huertos , Manuel Causse Del Río , Francisco Javier González García , Antonio Álvarez Kindelan
{"title":"Mucormycosis Infection in Lung Transplant Patients: Experience in Andalusia, Spain","authors":"Alba María Fernández González , Ninoska Moreira Lorenzo , Benito Cantador Huertos , Manuel Causse Del Río , Francisco Javier González García , Antonio Álvarez Kindelan","doi":"10.1016/j.transproceed.2024.11.030","DOIUrl":"10.1016/j.transproceed.2024.11.030","url":null,"abstract":"<div><h3>Introduction</h3><div>Mucorales infections in the airways of lung transplant (LT) patients are rare but have a rising incidence in transplanted lungs.</div></div><div><h3>Objective</h3><div>We present our experience with LT in immediate postoperative infections due to mucormycosis.</div></div><div><h3>Methods</h3><div>Review of 767 LT performed in Andalusia between 2000 and 2023 identifying Mucorales through microbiological results and histological findings.</div></div><div><h3>Results</h3><div>The incidence of Mucorales was less than 1% of all LTs performed at our institution but resulted in 100% mortality. In our series, all cases underwent LT for chronic obstructive pulmonary disease. They presented with pulmonary infection that progressed to disseminated infection. Major associated risk factors included prior corticosteroid treatment, malnutrition, solid organ transplantation, single lung transplantation, immunosuppression, and concomitant Aspergillus infection.</div></div><div><h3>Conclusions</h3><div>Mucormycosis infection in grafts after lung transplantation is a lethal complication poorly documented in the literature. Vigilance for Mucorales in these patients is crucial for early diagnosis.</div></div>","PeriodicalId":23246,"journal":{"name":"Transplantation proceedings","volume":"57 1","pages":"Pages 70-72"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142928966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ignacio Fernández-Granda , Rodrigo Alonso-Moralejo , Carlos-Andrés Quezada-Loaiza , Virginia-Luz Pérez-González , Francisco López-Medrano , Ana Pérez-Ayala , Beatriz González-Blanco , Iván Martínez-Serna , Felisa Jaén-Herreros , Alicia de Pablo-Gafas
{"title":"Infection by Trichosporon Inkin in Lung Transplant: Rare Infection, or Not So Rare?","authors":"Ignacio Fernández-Granda , Rodrigo Alonso-Moralejo , Carlos-Andrés Quezada-Loaiza , Virginia-Luz Pérez-González , Francisco López-Medrano , Ana Pérez-Ayala , Beatriz González-Blanco , Iván Martínez-Serna , Felisa Jaén-Herreros , Alicia de Pablo-Gafas","doi":"10.1016/j.transproceed.2024.12.002","DOIUrl":"10.1016/j.transproceed.2024.12.002","url":null,"abstract":"<div><div>The incidence of invasive fungal infections has increased in recent years among transplant patients, with <em>Trichosporon inkin</em> being a rare but relevant etiological agent. This study examines the experience of our multidisciplinary lung transplant unit in the diagnosis and treatment of 6 cases of <em>T. inkin</em> infection in transplant patients from 2016 to 2023. The cumulative incidence was 1.25% (6/480), with 2 temporal clusters: 5 cases between 2016 and 2017, and 1 case in 2023. The patients had a mean age of 59 ± 5.5 years, and all had undergone bilateral lung transplantation. The median time from transplantation to diagnosis was 53 days. Three patients (50%) presented with local dissemination, while the other three (50%) showed hematogenous spread, resulting in a 66.6% (2/3) mortality rate in the latter group. Treatment included the use of azoles, with voriconazole administered either as monotherapy or in combination with other antifungals such as amphotericin B, fluconazole or micafungin. The overall mortality was 33.3% (2/6). These findings highlight the importance of early diagnosis of <em>T. inkin</em> infection in lung transplant patients, as hematogenous dissemination is associated with a significantly worse prognosis. Azole therapy, combined with surgical interventions for localized infections, was effective in the majority of patients. Additional preventive measures were implemented following the initial 5 cases, including environmental cultures, carrier screening, and reverse isolation protocols.</div></div>","PeriodicalId":23246,"journal":{"name":"Transplantation proceedings","volume":"57 1","pages":"Pages 82-85"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142934191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alejandra Comins-Boo , Víctor Manuel Mora-Fernández , Paula Padrón-Aunceame , María Toriello-Suárez , Elena González-López , Adriel Roa-Bautista , Carolina Castro-Hernández , David Iturbe-Fernández , Manuel Cifrián José , Marco López-Hoyos , David San Segundo
{"title":"Non-HLA Antibodies and the Risk of Antibody-mediated Rejection without Donor-specific Anti-HLA Antibodies After Lung Transplantation","authors":"Alejandra Comins-Boo , Víctor Manuel Mora-Fernández , Paula Padrón-Aunceame , María Toriello-Suárez , Elena González-López , Adriel Roa-Bautista , Carolina Castro-Hernández , David Iturbe-Fernández , Manuel Cifrián José , Marco López-Hoyos , David San Segundo","doi":"10.1016/j.transproceed.2024.11.031","DOIUrl":"10.1016/j.transproceed.2024.11.031","url":null,"abstract":"<div><h3>Background</h3><div>Antibody-mediated rejection (ABMR) has become one of the leading causes of chronic lung graft dysfunction. However, in lung transplantation, this entity is sometimes difficult and controversial to diagnose. It is mainly caused by the appearance of donor-specific anti-human leukocyte antigen (HLA) antibodies (DSA), although there are situations with C4d deposits in biopsy in the absence of circulating DSA. The aim of this work was to study the potential role of non-HLA antibodies in the development of ABMR without DSA after lung transplantation.</div></div><div><h3>Methods</h3><div>A case-control study was designed with a cohort of lung transplant recipients at our institution. Twenty-seven patients with ABMR and without anti-HLA antibodies were identified after lung transplantation, and a control group of 21 transplant recipients was selected with the same post-transplant follow-up without evidence of rejection. Non-HLA antibodies were studied pretransplant using Luminex (ThermoFisher, One Lambda).</div></div><div><h3>Results</h3><div>The median of the pretransplant non-HLA–positive antibodies in the group with ABMR without DSA is significantly higher than in the control group: 2 (interquartile range, 0–16) vs 0 (interquartile range, 0–1; <em>P</em> < .01). Patients with >1.5 pretransplant non-HLA antibodies were more likely to develop ABMR without DSA (sensitivity, 80.95%; specificity, 55.55%; area under the curve, 71.3%).</div></div><div><h3>Conclusion</h3><div>The increase of non-HLA antibodies before lung transplantation has recently been shown to increase the risk of chronic lung allograft dysfunction. These results confirm that patients with a higher number of non-HLA antibodies could be at risk of developing ABMR without DSA. These results point out the possible usefulness of pre-lung transplant non-HLA antibodies to identify patients with end-stage lung disease at risk of developing ABMR without DSA.</div></div>","PeriodicalId":23246,"journal":{"name":"Transplantation proceedings","volume":"57 1","pages":"Pages 73-76"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142928967","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Camino Rodríguez-Villar, Andrea Tomás Pulgarín, Rebeca Roque Ardá, David Paredes-Zapata, Carolina Sanchez Marcos, Sabina Herrera Fernández, Ángel Ruíz Arranz
{"title":"Usefulness of Portable Ultrasound for the Diagnosis of Hepatic Steatosis and Degree of Agreement With Macroscopic and Microscopic Findings of the Hepatic Graft Accepted for Transplantation","authors":"Camino Rodríguez-Villar, Andrea Tomás Pulgarín, Rebeca Roque Ardá, David Paredes-Zapata, Carolina Sanchez Marcos, Sabina Herrera Fernández, Ángel Ruíz Arranz","doi":"10.1016/j.transproceed.2024.11.025","DOIUrl":"10.1016/j.transproceed.2024.11.025","url":null,"abstract":"<div><h3>Background</h3><div>The viability of the liver pre-transplant depends on the type of donor, age, medical history, circumstances of death, result of analytics, and complementary exploration of the abdominal cavity. Abdominal ultrasound is the initial option for the assessment of previously unknown liver disease, such as the qualitative determination of hepatic steatosis. The presence of hepatic steatosis is considered a risk factor for graft failure after liver transplantation, therefore, at the time of clinical assessment of the donor or its presence in the macroscopic assessment in the operating room can be cause for rejection of the organ by the transplant teams. The objective is the usefulness of ultrasound for the diagnosis of hepatic steatosis and degree of agreement with macroscopic and microscopic findings of the hepatic graft accepted for transplantation.</div></div><div><h3>Methods</h3><div>We analyzed the results of ultrasound in the population of donors accepted for assessment of the hepatic graft for transplantation and the correlation with the macroscopic finding determined by surgery in the operating room and with the microscopic finding determined by histology in the transplanted grafts. The determinations made describe the demographic variables of the different types of donors, probability of presenting hepatic steatosis, sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) of the use of ultrasound and degree of agreement with macroscopic and microscopic findings.</div></div><div><h3>Results</h3><div>Of the grafts evaluated, hepatic steatosis was described by ultrasound in 48 of 299 cases (16.05%) and by macroscopic aspect in 79 of 299 cases (26.4%). Coinciding in 29 of 79 (36.70%) of the cases (kappa = 0.328, <em>P</em> = .000). The 63.21% (189/299) of the livers evaluated were valid for transplantation. Of the valid grafts, 9.6% presented steatosis by ultrasound, 8.4% by macroscopy, and 21.4% by histology. An ultrasound that reports hepatic steatosis implies an increase of 1.87 of log-odds that the donor presents macroscopic steatosis (95% confidence interval [CI] = 3.34–12.65, <em>P =</em> .000) according to the binary logistic regression model. The sensitivity of ultrasound for hepatic steatosis based on microscopy was 29%, specificity 91%, PPV 66%, and NPV 68%.</div></div><div><h3>Conclusions</h3><div>Given the moderate or low agreement among ultrasound, macroscopy, and histology, the bedside portable ultrasound for the diagnosis of hepatic steatosis seems to be a method that undervalues the presence of hepatic steatosis in potential donors accepted for liver transplantation.</div></div>","PeriodicalId":23246,"journal":{"name":"Transplantation proceedings","volume":"57 1","pages":"Pages 43-47"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142960925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Living Donor Liver Transplantation Using Right Posterior Section Graft in a Human Immunodeficiency Virus/Hepatitis C Virus-Coinfected Patient With Hemophilia: A Case Report","authors":"Takanobu Hara , Ayaka Sato , Akihiko Soyama , Hajime Matsushima , Takashi Hamada , Hajime Imamura , Ayaka Kinoshita , Kazushige Migita , Yuta Kawaguchi , Tomohiko Adachi , Tetsuya Hara , Tomoyuki Endo , Susumu Eguchi","doi":"10.1016/j.transproceed.2024.12.033","DOIUrl":"10.1016/j.transproceed.2024.12.033","url":null,"abstract":"<div><h3>Background</h3><div>Liver transplantation is an important treatment option for liver cirrhosis in patients with HIV/HCV coinfection. In Japan, the limited number of deceased donors may force the selection of living donor liver transplantation. Appropriate graft selection is the key to success.</div></div><div><h3>Case presentation</h3><div>The patient, a 66-year-old male with hemophilia A, acquired HIV and HCV through blood transfusions. He had a multidrug-resistant HIV strain, requiring frequent changes in antiretroviral therapy. Although his HCV cleared spontaneously, liver fibrosis progressed. With a Child-Pugh score of 9 and a MELD score of 13, liver transplantation was considered. His child became the living donor. A factor VIII concentrate test was performed preoperatively, and his HIV treatment was adjusted to avoid drug interactions. The chosen graft was a posterior segment (graft-to-recipient weight ratio of 0.8), and surgery lasted 787 min with a blood loss of 7046 g. Factor VIII concentrate was stopped on the second postoperative day as activity increased. The patient was discharged on postoperative day 47.</div></div><div><h3>Conclusion</h3><div>This is the first reported living donor liver transplantation using a posterior segment graft in a hemophilia patient coinfected with HIV and HCV. Liver transplantation can be safely performed by formulating a preoperative coagulation factor supplementation protocol.</div></div>","PeriodicalId":23246,"journal":{"name":"Transplantation proceedings","volume":"57 1","pages":"Pages 122-125"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142967684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hany M. El Hennawy , Eisa Al Atta , Amal Awadh , Omar Safar , Shaher Al Kawasmeh , Yasser S. Mansour , Mohammad F. Zaitoun , Abdullah S. Al Faifi
{"title":"Successful Vascular Graft Reconstruction of Short Renal Artery Using Polytetrafluoroethylene (PTFE) in Living Donor Kidney Transplantation—A Case Report and Review of Literature","authors":"Hany M. El Hennawy , Eisa Al Atta , Amal Awadh , Omar Safar , Shaher Al Kawasmeh , Yasser S. Mansour , Mohammad F. Zaitoun , Abdullah S. Al Faifi","doi":"10.1016/j.transproceed.2024.11.013","DOIUrl":"10.1016/j.transproceed.2024.11.013","url":null,"abstract":"<div><div>Short donor renal artery during nephrectomy poses a technical challenge. We present a main renal artery (RA) reconstruction case in Living-donor kidney transplantation (LDKT) using an extension polytetrafluoroethylene vascular graft(PTFE). A 57-year-old man received LDKT from his son. Postlaparoscopic donor nephrectomy, a PTFE graft was used to reconstruct the short RA. Excellent reperfusion, good renal turgor, and immediate urine production were noted. Serial Doppler assessments on postoperative days 1, 3, and 7 and 180 confirmed good blood flow. The PTFE graft did not cause any additional morbidity or complications related to kidney transplantation.</div></div>","PeriodicalId":23246,"journal":{"name":"Transplantation proceedings","volume":"57 1","pages":"Pages 100-104"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142782145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}