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Adaptation of the gymnosperms to the conditions of irradiation in Chornobyl zone: from morphological anomalies to the molecular genetic consequences. 裸子植物对切尔诺贝利辐射条件的适应:从形态异常到分子遗传后果。
TSitologiia i genetika Pub Date : 2016-11-01
A I Yemets, R Ya Blume, B V Sorochinsky
{"title":"Adaptation of the gymnosperms to the conditions of irradiation in Chornobyl zone: from morphological anomalies to the molecular genetic consequences.","authors":"A I Yemets,&nbsp;R Ya Blume,&nbsp;B V Sorochinsky","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>It is known that the most suitable plant indicator targets for radiation pollution biomonitoring are conifers, because they have high radiosensitivity. In this review are briefly considered previously accumulated information about the genetic nature of morphological abnormalities in gymnosperms, induced by acute and chronic irradiation in the exclusion zone of the Chornobyl nuclear power plant. Since in the last decade appeared additional number of important research results, dedicated to the analysis of molecular biological and molecular genetic effects of chronic irradiation on the coniferous plants growing in the exclusion zone of the Chornobyl disaster, all these results are also analyzed in current review.</p>","PeriodicalId":23230,"journal":{"name":"TSitologiia i genetika","volume":"50 6","pages":"80-9"},"PeriodicalIF":0.0,"publicationDate":"2016-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36713525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Experience of thyroid gland status screening in postchernobyl period. 切尔诺贝利事故后甲状腺状态筛查的体会。
TSitologiia i genetika Pub Date : 2016-11-01
V M Drozd, M L Lushchyk, L I Danilova, N M Okulevich, I G Shimanskaya, T A Mitiukova, N Shiglik, I Branovan
{"title":"Experience of thyroid gland status screening in postchernobyl period.","authors":"V M Drozd,&nbsp;M L Lushchyk,&nbsp;L I Danilova,&nbsp;N M Okulevich,&nbsp;I G Shimanskaya,&nbsp;T A Mitiukova,&nbsp;N Shiglik,&nbsp;I Branovan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The main results of thirty-year period of repeated screening programs and observational studies in contaminated and non-contaminated regions of Belarus are analyzed. The possible reasons of discrepant and contradictory data about the consequences of Chernobyl catastrophe delivered by different study groups during early period after the accident are discussed. High incidence of thyroid nodular disease and cancer in children and adolescence after the catastrophe are described. The research shows high effectiveness of screening in early diagnosis thyroid disorders and radiation-induced thyroid cancer in different regions of Belarus and in various time points.</p>","PeriodicalId":23230,"journal":{"name":"TSitologiia i genetika","volume":"50 6","pages":"8-14"},"PeriodicalIF":0.0,"publicationDate":"2016-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36713082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Morphological evaluation of the effectiveness of bipolar radiofrequency ablation for thyroid nodules. 双极射频消融治疗甲状腺结节有效性的形态学评价。
TSitologiia i genetika Pub Date : 2016-11-01
I Branovan, M Fridman, M Lushchyk, V Drozd, O Krasko, O Nedzvedz, N Shiglik, L Danilova
{"title":"Morphological evaluation of the effectiveness of bipolar radiofrequency ablation for thyroid nodules.","authors":"I Branovan,&nbsp;M Fridman,&nbsp;M Lushchyk,&nbsp;V Drozd,&nbsp;O Krasko,&nbsp;O Nedzvedz,&nbsp;N Shiglik,&nbsp;L Danilova","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Recently, radiofrequency ablation has been increasingly used for the treatment of thyroid nodules. The widespread introduction of this method, however, hampered by the lack of data on efficacy and safety of different devices that are currently on the market, the selection of the optimal mode of procedure also remains to be elucidated. Experimental data obtained during the application of the original patented device is presented. The results make it possible to move from ex vivo experiments to clinical practice.</p>","PeriodicalId":23230,"journal":{"name":"TSitologiia i genetika","volume":"50 6","pages":"29-33"},"PeriodicalIF":0.0,"publicationDate":"2016-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36713083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
30 years of the Chernobyl accident. Molecular genetic mechanisms of carcinogenesis of thyroid gland. 切尔诺贝利事故30周年。甲状腺癌变的分子遗传机制。
TSitologiia i genetika Pub Date : 2016-11-01
N D Tronko, V M Pushkarev
{"title":"30 years of the Chernobyl accident. Molecular genetic mechanisms of carcinogenesis of thyroid gland.","authors":"N D Tronko,&nbsp;V M Pushkarev","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The review presents data on the basic molecular ge-netic mechanisms of formation of papillary thyroid carcinoma. The participation of ionizing radiation in the cancer pathogenesis was analyzed. The role of tu-mor microenvironment, inflammation and nuclear trans-cription factor NF-κB in the initiation and development of papillary thyroid carcinoma was shown.</p>","PeriodicalId":23230,"journal":{"name":"TSitologiia i genetika","volume":"50 6","pages":"15-22"},"PeriodicalIF":0.0,"publicationDate":"2016-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36713081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chornobyl thirty years later: evaluation of the consequence by biologists and medics Experience of thyroid gland status screening in postchernobyl period. 切尔诺贝利三十年后:生物学家和医务人员对后果的评价切尔诺贝利后时期甲状腺状况筛查的经验。
TSitologiia i genetika Pub Date : 2016-11-01
Ya B Blume, D M Grodzinsky
{"title":"Chornobyl thirty years later: evaluation of the consequence by biologists and medics Experience of thyroid gland status screening in postchernobyl period.","authors":"Ya B Blume,&nbsp;D M Grodzinsky","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Summarizing paper contains short analysis of the publications resulting cell biological, molecular genetic and population genetic investigations devoted to studying of accute radiation exposure and chronic radiation contamination effects on biological systems after disaster on Chornobyl nuclear power station in 1986.</p>","PeriodicalId":23230,"journal":{"name":"TSitologiia i genetika","volume":"50 6","pages":"3-7"},"PeriodicalIF":0.0,"publicationDate":"2016-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36713079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Systems biology is an efficient tool for investigation of low-dose chronic irradiation influence on plants in the Chernobyl zone. 系统生物学是研究低剂量慢性辐照对切尔诺贝利地区植物影响的有效工具。
TSitologiia i genetika Pub Date : 2016-11-01
M Danchenko, K Klubicova, M V Krivohizha, V V Berezhna, V I Sakada, M Hajduch, N M Rashydov
{"title":"Systems biology is an efficient tool for investigation of low-dose chronic irradiation influence on plants in the Chernobyl zone.","authors":"M Danchenko, K Klubicova, M V Krivohizha, V V Berezhna, V I Sakada, M Hajduch, N M Rashydov","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The paper discusses different methodological approaches to the study of transgenerational alterations of metabolic pathways in soybean and flax seeds in the process of adaptation to chronic irradiation in the Chernobyl alienation zone. A combination of general biological methods and novel approaches, such as genomics, proteomics, cytogenetics, and mutagenesis, allows researchers to analyze an organism’s systemic response and identify the latent chronic irradiation effects in plants from the Chernobyl zone. The proteomic approaches are especially efficient, since they range from the identification of changes in abundance and folding of individual proteins to the characterization of posttranslational modifications, trends of qualitative changes during seed maturation, or protein-protein interactions during plant growth and development under permanent impacts of stress factors. The application of proteomics opens new horizons in the understanding of the hidden mechanisms behind the impact of chronic low-dose radiation on living cells and makes it possible to visualize metabolic network alterations regardless of their transcriptional, translational, or epigenetic nature.</p>","PeriodicalId":23230,"journal":{"name":"TSitologiia i genetika","volume":"50 6","pages":"60-79"},"PeriodicalIF":0.0,"publicationDate":"2016-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36713522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IFNL4 polymorphism as a predictor of chronic hepatitis C treatment efficiency in Ukrainian patients. IFNL4多态性作为乌克兰慢性丙型肝炎患者治疗效率的预测因子
TSitologiia i genetika Pub Date : 2016-09-01
A Kucherenko, V Pampukha, K Romanchuk, S Chernushyn, I Bobrova, L Moroz, L Livshits
{"title":"IFNL4 polymorphism as a predictor of chronic hepatitis C treatment efficiency in Ukrainian patients.","authors":"A Kucherenko,&nbsp;V Pampukha,&nbsp;K Romanchuk,&nbsp;S Chernushyn,&nbsp;I Bobrova,&nbsp;L Moroz,&nbsp;L Livshits","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The aim of this study was to examine association between IFNL4 gene ss469415590 and treatment efficiency in group of Ukrainian PEG-interferon/ribavirin-treated chronic hepatitis C patients. Study group consisted of 92 unrelated hepatitis C virus genotype 1 mono-infected patients: case group - 29 patients with late or absent virological response; control group - 63 patients with sustained virological response. Study material was genomic DNA. Genotyping was performed using amplification-refractory mutation system PCR. Statistical analysis was performed using GenePop and OpenEpi statistical packages. Obtained results show that ss469415590 ΔG/ΔG genotype is associated with poor virological response (OR = 3.62; CI 95%: 1.12-11.67) in PEG-interferon/ribavirin-treated chronic hepatitis C patients from Ukraine.</p>","PeriodicalId":23230,"journal":{"name":"TSitologiia i genetika","volume":"50 5","pages":"79-84"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36770246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intra- and intertissular cytomictic interactions in mic-rosporogenesis of mono- and dicotyledonous plants. 单子叶和双子叶植物微孢子发生过程中的组织内和组织间细胞相互作用
TSitologiia i genetika Pub Date : 2016-09-01
E A Kravets, Yu V Sidorchuk, I I Horyunova, S H Plohovskaya, S R Mursalimov, E V Deineko, A I Yemets, Ya B Blume
{"title":"Intra- and intertissular cytomictic interactions in mic-rosporogenesis of mono- and dicotyledonous plants.","authors":"E A Kravets, Yu V Sidorchuk, I I Horyunova, S H Plohovskaya, S R Mursalimov, E V Deineko, A I Yemets, Ya B Blume","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A comparative cytological analysis of intra- and intertissular cytomictic interactions in early micro-sporogenesis of mono- and dicotyledonous plants was performed by the example of the two cellular systems - microsporocytes and tapetum. It is found that cytomixis is the component of intratissular interactions mainly. In the tapetum cells cytomixis is notable for structural and temporary taxon specific features. The nuclear migration in microsporocytes is confined mainly to zygotene-pachytene meiotic stages and characterized by a certain synchronism with cytomixis at the tapetum. Intertissular cytomictic interactions (tapetum - microsporocytes) were found in the monocot anthers only. Intertissular interactions are likely to reflect the intensification of competitive relations between the tapetum and microsporocytes for area in the process of anther tissue differentiation. Polyploid tapetum nucleus and syncytia being powerful acceptors are able to compete with microsporocytes and direct the chromatin translocation to their favor. The absence of intertissular interactions in dicots probably reflects a better balance between the processes of differentiation at somatic and generative tissues into microsporangium compared to monocots.</p>","PeriodicalId":23230,"journal":{"name":"TSitologiia i genetika","volume":"50 5","pages":"3-16"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36710516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Specific features of root aerenchyma formation in Sium latifolium L. (Apiaceae). 安科荷叶根通气组织形成的特殊特征。
TSitologiia i genetika Pub Date : 2016-09-01
G V Shevchenko, V A Brykov, G F Ivanenko
{"title":"Specific features of root aerenchyma formation in Sium latifolium L. (Apiaceae).","authors":"G V Shevchenko,&nbsp;V A Brykov,&nbsp;G F Ivanenko","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Types of aerenchyma formation in adventive roots of wild plant S. latifolium L. are described for the first time. Specific cell divisions and patterns of cell growth in the inner and outer root cortex at the initial stages of aerenchyma formation are highlighted in detail. Destructive processes in cells occurred under aerenchyma formation are considered in the view of known stages of programmed cell death in plants.</p>","PeriodicalId":23230,"journal":{"name":"TSitologiia i genetika","volume":"50 5","pages":"34-42"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36710521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Anatomical abnormalities of the intertribal cybrid between Brassica napus and Lesquerella fendleri. 甘蓝型油菜与小茴香部落间杂种的解剖异常。
TSitologiia i genetika Pub Date : 2016-09-01
N V Nuzhyna, I O Nitovska, I O Golubenko, A V Morgun, M V Kuchuk
{"title":"Anatomical abnormalities of the intertribal cybrid between Brassica napus and Lesquerella fendleri.","authors":"N V Nuzhyna,&nbsp;I O Nitovska,&nbsp;I O Golubenko,&nbsp;A V Morgun,&nbsp;M V Kuchuk","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The anatomical research of the vegetative organs of the cytoplasmatic hybrid in vitro plants containing the Brassica napus nucleus and the Lesquerella fendleri chloroplasts had been conducted in comparison to the parental forms. It was found, that the anatomical structure of the cybrid had been similar to rapeseed. Anomalous changes in the epithelial, parenchymal and connective tissue of the leaf, stalk, stem, and root of the cybrid were detected. The appearance of the anatomical defects can be explained by nuclear-cytoplasmatic incompatibility which is the cause of low adaptability of the cybrid to in vivo conditions and takes place due to alien chloroplast gene expression in the remote species.</p>","PeriodicalId":23230,"journal":{"name":"TSitologiia i genetika","volume":"50 5","pages":"25-33"},"PeriodicalIF":0.0,"publicationDate":"2016-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36710520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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