Ukrainian Journal of Veterinary and Agricultural Sciences最新文献

{"title":"A long-term analysis of the common agricultural policy financial subsidies towards Italian farms","authors":"N. Galluzzo","doi":"10.32718/ujvas2-1.03","DOIUrl":"https://doi.org/10.32718/ujvas2-1.03","url":null,"abstract":"In Italy since 2000 there has been a significant decrease of farms and a notable increase of the usable agricultural areas. In order to reduce the socioeconomic marginalization in rural territories the European Union has supported financially the rural development in a pattern of pluriactivity and productive diversification in farms. The core purpose of this research was to assess by a multiple regression model the impact of financial subsidies allocated by the Common Agricultural Policy on the farmer net income since 2004 to 2016 in Italian farms belonging to the Farm Accountancy Data Network. Findings have pointed out a direct impact of financial supports disbursed by the European Union; by contrast, no impacts have had payments disbursed by the second pillar. Drawing the conclusions, it is fundamental to increase the financial supports of the Common Agricultural Policy aimed at implementing the land capital endowment which is the one of the main bottlenecks in Italian farms.","PeriodicalId":231752,"journal":{"name":"Ukrainian Journal of Veterinary and Agricultural Sciences","volume":"197 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114268197","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The formation of colostral immunity and its duration in calves during the first months of life","authors":"D. Masiuk, A. Kokariev, T. Vasilenko, K. O. Krutii","doi":"10.32718/UJVAS2-1.01","DOIUrl":"https://doi.org/10.32718/UJVAS2-1.01","url":null,"abstract":"The paper presents the results of a study on the formation of colostral immunity and the determination of its duration during the first months of life of calves according to the indications of the level of total IgG and antigen-specific antibodies to pathogens of рarainfluenza 3, respiratory syncytial infection and viral diarrhea of cattle. It has been established that blood serum of newborn calves does not contain antigen-specific immunoglobulins of class G to pathogens of viral diarrhea, respiratory syncytial infection and parainfluenza-3, and the level of total IgG is 2.2 ± 0.61 g/dm3. The concentration of total IgG is increased to 50.50 ± 6.33 g/dm3, and decreases to 27.25 ± 5.82 g/dm3 for 28 days, which contributes to the formation of the immunosuppressive state at the 7th day of a calf life. Starting from 35th day, there is an increase in the concentration of total IgG due to seroconverting of its own antibodies by the body of calves. Immunization of cows-mothers against viral diarrhea, respiratory syncytial infection and parainfluenza-3 contributes to the formation of antigen-specific colostral immunity in calves in the first days of life, which is preserved in diagnostic titers during 63 days after birth.","PeriodicalId":231752,"journal":{"name":"Ukrainian Journal of Veterinary and Agricultural Sciences","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127799029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Benefit of dorsal laminectomy without lumbosacral stabilization in lumbosacral traumatic cat","authors":"Piyabongkarn Damrongdej","doi":"10.32718/ujvas2-1.05","DOIUrl":"https://doi.org/10.32718/ujvas2-1.05","url":null,"abstract":"Two cats were diagnosed with depression of caudal equina spinal nerve and lumbosacral spinal trauma that revealed rapid improving clinical signs after 1 month of dorsal laminectomy at the region of lumbar and sacral vertebrae without internal and external stabilization devices. This report showed that dorsal laminectomy was a powerful procedure for decompression caudal equina spinal injuries in stable lumbosacral vertebral trauma in cats without ancillary fixation methods. Dorsal laminectomy is valuable technique for correction of fracture/luxation of vertebrae that this procedure can reduce spinal cord edema, and axonal disruption. Stabilization of vertebrae by the orthopedic implants may be not necessary in small cat that has enough vertebral stability as the same in two these cases.","PeriodicalId":231752,"journal":{"name":"Ukrainian Journal of Veterinary and Agricultural Sciences","volume":"292 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117284643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of insulin-like growth factor and leptin in the pathogenesis of internal non-contagious pathology of dairy cows","authors":"I. Petruh, M. Simonov, V. Vlizlo, D. Ostapiv","doi":"10.32718/ujvas1-2.05","DOIUrl":"https://doi.org/10.32718/ujvas1-2.05","url":null,"abstract":"The endocrine system plays a key role in the pathogenesis of the non-infectious pathology of dairy cows. However, the role of a number of hormones in pathology is not clear. These hormones include insulin-like growth factors and leptin. The insulin-like growth factor is synthesized predominantly in the liver in response to an increase in the level of somatotropic hormone in the blood. According to its physiological properties, it is close to insulin, structurally similar, has common receptors that trigger the same chain of reactions: stimulates transport of amino acids and glucose in the muscles, increases the sensitivity of cells to insulin, in adipose tissue, transport glucose, oxidation of glucose to carbon dioxide, the inclusion of glucose in lipids. Leptin is synthesized by adipocytes, and its main physiological function is to reduce the synthesis of macroergic compounds and increase energy expenditure. Circulating in the blood, it helps to maintain an optimal level of glucose, which is necessary for the energy needs of the body. The purpose of this study was to investigate the concentration of insulin-like growth factor, leptin, glucose, pyruvate and lactate in the blood of cows under secondary osteodystrophy, ketosis and hepatodistrophy. This will give an opportunity to better understand the pathogenesis and create theoretical preconditions for the development of informative diagnostic tests and effective means of treatment. The experiment was conducted on dairy cows, analogues by age, breed, productivity and physiological state. According to clinical features, urine analysis and values of biochemical parameters of blood of experimental cows were divided into four groups: 1 – clinically healthy cows, 2 – patients with osteodystrophy, 3 – patients with ketosis, 4 – patients with hepatodistrophy. The obtained results of research indicate that the internal non-contagious pathology in dairy cows deficiency of exchange energy is recorded, which induces an increase in the activity of gluconeogenesis and is expressed by lowering the concentration of glucose and increasing the content of pyruvate and lactate. At the same time, a decrease in the level of insulin-like growth factor and leptin was found. The lowest level of insulin-like growth factor and leptin was determined by ketosis. The decrease in the level of tissue hormones in the blood plasma of cows under osteodystrophy was within the statistical error.","PeriodicalId":231752,"journal":{"name":"Ukrainian Journal of Veterinary and Agricultural Sciences","volume":"189 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134088031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disinvasive efficacy of chlorine-based preparations of domestic production for eggs of nematodes of the species Aonchotheca bovis parasitizing in sheep","authors":"V. Melnychuk, I. Yuskiv","doi":"10.32718/ujvas1-2.04","DOIUrl":"https://doi.org/10.32718/ujvas1-2.04","url":null,"abstract":"The paper presents the results of experimental researches on the determination of the disinvasion efficiency of chlorinated chemical preparations of domestic production of “Brovades-plus”, “Bi-dez” and “Dezsans” of NPF “Brovafarma” (Ukraine). The conducted researches on the basis of the parasitology laboratory found that the studied disinfectants possess disinvasive properties in respect of non-invasive test culture of eggs of nematodes of the species Aonchotheca bovis (son Capillaria bovis) López-Neyra, 1947, isolated from gonads of females of worms. The dissimilar stability of eggs of capillaries to the effect of the tested agents in vitro is proved. The most effective disinfectant in the case of eggs of capillaries of the species A. bovis was the preparation “Dezsan”. The high level of its disinvasive efficacy (DE – 91.14–100.0%) was registered at the application of the preparation in 1.0–2.0% of the exposure concentration for 10–60 minutes. The chemicals “Bi-dez” and “Brovadez-plus” proved to be less effective in the relatively non-invasive test culture of A. bovis eggs. The high level of efficiency (DE –92.41–100.00%) of the “Bi-dez” was achieved with its use at concentrations of 1.5% (exposure of 30 and 60 min) and 2.0% (exposure of 10–60 minutes) The “Brovadez plus” preparation in vitro proved to be the least effective means of non-invasive test culture of nematode eggs of the species A. bovis, since a high level of disinvasive efficacy (DE – 100.00%) was achieved only with the use of 2.0% solution per exposure 10–60 min. It was established that the experimentally tested chlorine-based means of domestic production resulted in the death of eggs in the culture in due to the destructive effect of the components of the preparations on the shell, the caps of eggs of the capillaries, as well as on the germ in the middle of the egg. In experimental cultures treated with the means, the destruction of the shell of the egg in the location of the caps, the exit of morulae outside, the cessation of development or shrinkage of the embryo and deformation of the egg shell were recorded.","PeriodicalId":231752,"journal":{"name":"Ukrainian Journal of Veterinary and Agricultural Sciences","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124031742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypocobaltosis and hypocuprosis in pregnant mares in the western biogeochemical zone of Ukraine (distribution, diagnosis)","authors":"A. Shcherbatyy, L. Slivinska, B. Lukashchuk","doi":"10.32718/ujvas1-2.03","DOIUrl":"https://doi.org/10.32718/ujvas1-2.03","url":null,"abstract":"The article presents theoretical and experimental substantiation of relationship between the content of trace elements in the soil, water, feed and blood of mare with hypocobaltosis and hypocuprosis in biogeochemical province of Transcarpathia. The total content of Zn in soils is 50.96 mg/kg, Cu – 16.32, Co – 7.14, and Mn – 493.97 mg/kg. It was established decrease in the concentration of mobile forms of Cu and Co (0.01mg /kg), Cr (1.93), Pb (1.66), Ni (0.67), Zn (1.42). Also, in water from artesian wells of research farm it was established decreased content of Co (by 3.3 times), Cu (111), Zn (1.19), Mn (1.31), Cd (5.0 times) and on the contrary increased content of Pl by 5.6, Ni – 3.3 and Fe – 43.5 times. Providing of mares by Co is 54.7%, Cu – 88.5, Zn – 83.3, Fe – 88.4, Mn by 29%. The negative effect of Cobalt and Copper deficiency on erythrocytopoesis is shown. In particular, the number of erythrocytes, hemoglobin level, hematocrit value, and hemoglobin content in the erythrocyte indicate a development of alimentary anemia in pregnant mares. The established low level of Co and Cu that indicates the development of polymicroelementosis in mares. The Cobalt content in blood of non-pregnant mares was on the lower physiological limit and on average it was 0.48 ± 0.02 μmol/l. In the mares, at 7 month of pregnancy, the Cobalt content was lower (P < 0.01) than that of non-pegnant. In the 9–11 months of pregnancy, its level was on average 0.19 ± 0.02 μmol/l, which is lower by 2.5 and 1.9 times than in non-pregnant mares (P < 0.001) and at 4 months of pregnancy (P < 0.05). The Copper content in blood of mares at 9–11 months of pregnancy was lowest and the average was 2.09 ± 0.07 μmol/l (1.98–2.27), which is lower on 46.8 and 22.6% (P < 0.001) compared to non-pregnant and mares at 4 month of pregnancy. Hypocopperemia was established in 100% of studied mares. In non-pregnant mares, the Copper content was on average 3.93 ± 0.14 μmol/l. Taking into account the role of these microelements in metabolic transformations, changes in the composition of blood and the development of metabolism disorders in the organism of mares during the period of pregnancy can be explained.","PeriodicalId":231752,"journal":{"name":"Ukrainian Journal of Veterinary and Agricultural Sciences","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126872833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Productivity of growing rabbits for use of forrage with different zinc content","authors":"Yu. V. Pozniakovskyi, M. Holubiev, T. Holubieva","doi":"10.32718/UJVAS1-2.01","DOIUrl":"https://doi.org/10.32718/UJVAS1-2.01","url":null,"abstract":"The results of studies on the optimal level of zinc, which are additionally introduced into feed for rabbits grown for meat, are presented. Experimental researches were conducted in the conditions of the problematic research laboratory of feed additives of the National University of Life and Environmental Sciences of Ukraine. A scientific and economic experiment was carried out on young rabbits of HYLA hybrids of the French company EUROLAP. The study was conducted by group method. In the 42-day age, 60 rabbits were selected, out of which, according to the analogues principle, three groups were formed – one control and two experimental, with 20 rabbits (10 females and 10 males) in each. The research lasted for 42 days. It was used full-grain granulated feed for feeding the experimental young rabbits, which according to the chemical composition differed in content of zinc in them. Rabbits of the control group received feed containing zinc 50 mg/kg, the second – 100 mg/kg, the third – 150 mg/kg. It was established that feeding of rabbits in the 43–84-day-old age with feed containing zinc 100 mg/kg contributes to an increase in body weight by 2.9%, and an increase in average daily growth during the growing season, respectively, by 4.7%. Feed costs per 1 kg growth in young rabbits consuming feed containing Zinc were 1.0% lower than the control group's young. Rabbits which were fed with feed containing zinc 150 mg/kg were inferior to body weight and average daily increments, respectively, by 1.4% and 2.7% of animals fed with a feed with a zinc level of 50 mg/kg.","PeriodicalId":231752,"journal":{"name":"Ukrainian Journal of Veterinary and Agricultural Sciences","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123910711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Meat quality of obroshyno grey geese while their cultivation","authors":"M. Petriv, L. Sloboda, O. Sloboda","doi":"10.32718/UJVAS1-2.02","DOIUrl":"https://doi.org/10.32718/UJVAS1-2.02","url":null,"abstract":"The process of cultivating obroshyno gray geese improved their meat qualities. In particular, we determined by our researches that, based on the indicators of live weight, the males of the II group (4726 g) prevailed geese of the I and II groups (1.02%), while females of the ІІ group (4153 g) prevailed all groups by 4.19%. The weight of non-eviscerated males of the II group was 4116 g, which is 3.78% higher than that of males of the group I, while females of the group ІІ (3461 g) surpassed other geese by this indicator by 5.10%. The weight of eviscerated of carcasses of males of the II group was 3211 g, which is 3.5% higher than that of males of group I, while females of the second group (2738 g) surpassed others by 6.6%. The outcome of edible parts in the young geese of experimental groups was quite high, but the highest was the young in the second group. In males of the second group, this inicator was 61.5%, and females – 58.9%. The weight of the chilled carcasses of males of the II group was 3120 g, which was 3.93% higher than that of the males of the group I, while the females of the second group (2691 g) surpassed others by 7.04%. The weight of the skin with subcutaneous fat in males of the second group was 706 g, which is 3.67% higher than that of male of the group I (681 g), while females of group II (632 g) surpassed others by 4.64%. The mass of internal fat in males of the ІІ group was 111 g, which is 15.62% higher than that of male of the I group (95 g), while females of ІІ group (72 g) exceeded others by 12.5%. The weight of the muscles in the males of the second group was 1695 g, which is 8.58% higher than that of the male of the group I (1561 g), and the females of the second group (1399 g) surpassed others by this indicator – by 7.6%. The obtained data indicate that the most intense accumulation of dry matter in the chest muscles up to 9 weeks of age occurs in geese of the II group. A similar situation is observed in the femoral muscles. At 9 weeks of age, the males of the second group had 29.74% of the dry matter in the breast muscle of the crude mass, females – 27.35% of the crude mass, and in males of the I group – 27.74%, of females – 27.30%. The same regularity in the content of dry matter is noted in the femoral muscle. The accumulation of protein in the studied muscles of geese, as the main indicator of meat quality, was in accordance with the general laws. The highest rate was in the thoracic and femoral muscles of males and females of the II group. The highest level of total nitrogen content in the muscles was found in males of the second group. In experimental geese, the accumulation of protein nitrogen in the chest muscle is higher than in the muscles of the legs. This indicator is higher in males than females. According to the content of albuminous nitrogen in the chest muscle, the highest rate was observed in males II group (3425 mg%). Non-protein nitrogen in the chest muscles and leg muscles increased to 9 weeks of age","PeriodicalId":231752,"journal":{"name":"Ukrainian Journal of Veterinary and Agricultural Sciences","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-11-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128678101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of phytobiotic for prophylactic non-contagious gastrointestinal diseases in suckling piglets","authors":"B. Lukashchuk, L. Slivinska, A. Shcherbatyy","doi":"10.32718/UJVAS1-1.05","DOIUrl":"https://doi.org/10.32718/UJVAS1-1.05","url":null,"abstract":"The article presents the results of prophylactic effectiveness phytobiotic feed additive XTRACT™ 6930 for non-contagious diseases of the gastrointestinal tract in the composition of the basic diet of suckling pigs on modern pig farm. Diseases of the gastrointestinal tract make up from 40 to 60% of internal pathology in pigs. Used phytobiotic XTRACT™ 6930 with preventive measures, which had positive influence on oxygen-transport function of blood, hemoglobin synthesis and erythrocytopoesis in animals, as indicated by the number of erythrocytes, MCH and hematocrit in blood of suckling piglets from experimental group. Feeding of XTRACT™ 6930 had also positive influence on leukopoesis, as indicated by increased leukocyte rate in blood of suckling piglets from experimental group within physiological fluctuations. Increase of leukocyte rate can be caused by stimulation of non-specific resistance in piglets, which plays main role in defence of animals during early ontogenesis. As it is known, stabilization of phagocytic activity of leukocytes occurs during first months of age, when the body of pigs is able to synthesize most humoral factors of protection. Application of suckling piglets feed additive XTRACT™ 6930 for 18 days resulted in a positive impact on metabolism: increased levels of total protein, albumin, glucose serum; reduced levels of urea, phosphorus; reduced the activity of ALT, AST, ALP and GGT within physiological fluctuations. The use of phytobiotic feed additive XTRACT™ 6930 in experimental group of piglets increased the survival of piglets from experimental group in sucking period compared with control group of animals by reducing the percentage of morbidity and mortality from non-contagious diseases of the gastrointestinal tract. Consequently, it was established that the use XTRACT™ 6930 has positive effect on biochemical blood parameters of piglets, decreases their morbidity and mortality before weaning.","PeriodicalId":231752,"journal":{"name":"Ukrainian Journal of Veterinary and Agricultural Sciences","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134224392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preclinical research of the experimental preparation “Ferosel T”","authors":"V. Todoriuk, V. Hunchak, B. Gutyj, D. Gufriy, I. Hariv, R. Khomyk, R. O. Vasiv","doi":"10.32718/UJVAS1-1.01","DOIUrl":"https://doi.org/10.32718/UJVAS1-1.01","url":null,"abstract":"The results of preclinical studies of the new ferrodextran preparation “Ferosel T”, which contains ferrum and selenium, are presented. It has been established that at oral administration of ferrocellus T in a prophylactic dose of 2 ml/kg b.w. and the therapeutic dose of 4 ml/kg for 3 days in a row in the stomach of laboratory rats did not show toxic effects. No toxic effect of T ferrocellus is established at introducing it into the stomach in doses in 3 and 10 times higher than the therapeutic ones. Under conditions of subcutaneous administration of the drug, the death of white rats was not observed, only short-term inhibition of laboratory animals, which was prescribed the drug in a dose of 10 ml/kg b.w. It was established that in the preventive and optimal therapeutic doses the drug did not affect the detoxification function of the liver. In rats, which ferrocellus T was administered at maximum therapeutic and possibly toxic doses, the duration of hexenal sleep was for 32 and 35% higher relative to control values. The investigation of the emotional and behavioral reactions of laboratory animals after administration of ferrocellus T for 21 days in therapeutic and maximum therapeutic doses did not show a significant effect on the nervous system. In terms of hyperemia and swelling of the skin and the thickness of the skin, ferrocellus T in prophylactic and therapeutic doses upon application to rabbit skin did not cause local irritation. Separate injection of the drug “Ferosel T” by sub-planar way to guinea pigs in 0.1 ml. did not cause swollen reactions of the paws. As a result of the conducted research, no allergenic properties of the drug “Ferosel T” were found. In laboratory rats, which were introduced ferrosel T in the prophylactic dose of probable changes in the weight of the heart, liver, spleen and kidneys is not established. In rats, which were administered ferrocellus T in an optimal therapeutic dose, in comparison with control weights of the spleen and liver, respectively, was in 10.3 and 6.4% higher. When introducing ferrocellus T at the maximum therapeutic dose, the mass of the spleen and liver was in 14.0 and 15.0% higher, respectively. The results of the studies indicate that the drug “Ferosel T” is safe when used for the prevention and treatment of animals.","PeriodicalId":231752,"journal":{"name":"Ukrainian Journal of Veterinary and Agricultural Sciences","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-07-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122230326","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}