D. Masiuk, A. Kokariev, T. Vasilenko, K. O. Krutii
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引用次数: 1
摘要
本文介绍了一项研究的结果,该研究是根据对牛的3型流感、呼吸道合胞感染和病毒性腹泻病原体的总IgG和抗原特异性抗体水平的指示,对犊牛最初几个月的初乳免疫的形成和其持续时间的测定进行的。结果表明,新生犊牛血清中不含针对病毒性腹泻、呼吸道合胞感染和副流感3型病原体的G类抗原特异性免疫球蛋白,总IgG水平为2.2±0.61 G /dm3。总IgG浓度升高至50.50±6.33 g/dm3, 28 d后降至27.25±5.82 g/dm3,导致犊牛第7天形成免疫抑制状态。从第35天开始,由于犊牛体内自身抗体的血清转化,总IgG的浓度有所增加。母牛对病毒性腹泻、呼吸道合胞体感染和副流感-3的免疫有助于犊牛在出生后最初几天形成抗原特异性的初侧免疫,并在出生后63天内保持诊断滴度。
The formation of colostral immunity and its duration in calves during the first months of life
The paper presents the results of a study on the formation of colostral immunity and the determination of its duration during the first months of life of calves according to the indications of the level of total IgG and antigen-specific antibodies to pathogens of рarainfluenza 3, respiratory syncytial infection and viral diarrhea of cattle. It has been established that blood serum of newborn calves does not contain antigen-specific immunoglobulins of class G to pathogens of viral diarrhea, respiratory syncytial infection and parainfluenza-3, and the level of total IgG is 2.2 ± 0.61 g/dm3. The concentration of total IgG is increased to 50.50 ± 6.33 g/dm3, and decreases to 27.25 ± 5.82 g/dm3 for 28 days, which contributes to the formation of the immunosuppressive state at the 7th day of a calf life. Starting from 35th day, there is an increase in the concentration of total IgG due to seroconverting of its own antibodies by the body of calves. Immunization of cows-mothers against viral diarrhea, respiratory syncytial infection and parainfluenza-3 contributes to the formation of antigen-specific colostral immunity in calves in the first days of life, which is preserved in diagnostic titers during 63 days after birth.