Trakya University Journal of Natural Sciences最新文献_第7页

THE FIRST REPORT OF GEOSMIN AND 2-METHYLISOBORNEOL PRODUCER CYANOBACTERIA FROM TURKISH FRESHWATERS 土耳其淡水中土臭素和2-甲基异龙脑蓝藻的首次报道

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Trakya University Journal of Natural Sciences Pub Date : 2021-06-16 DOI: 10.23902/trkjnat.884423

Zuhal Tunç, R. Akçaalan, Latife Köker, Meriç Albay

引用次数: 1

BIOMOLECULES AND NATURAL PRODUCTS REGULATE THE HUMAN ACE2 GENE EXPRESSION ON THE LUNG CANCER CELLS 生物分子和天然产物调控人ace2基因在肺癌细胞上的表达

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Trakya University Journal of Natural Sciences Pub Date : 2021-06-15 DOI: 10.23902/trkjnat.896013

Kaan Hürkan, Ş. Arslan, M. Atalar, A. Aydin, I. Demirtaş, Dogukan Mutlu, Bahattin Tabar, M. Alma

引用次数: 0

SYNTHESIS, CHARACTERIZATION AND BIOCOMPATIBILITY OF PLANT-OIL BASED HYDROGELS 植物油基水凝胶的合成、表征及生物相容性研究

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Trakya University Journal of Natural Sciences Pub Date : 2021-06-10 DOI: 10.23902/trkjnat.925742

Ozlem Yalcin Capan, Pinar Cakir Hatir

{"title":"SYNTHESIS, CHARACTERIZATION AND BIOCOMPATIBILITY OF PLANT-OIL BASED HYDROGELS","authors":"Ozlem Yalcin Capan, Pinar Cakir Hatir","doi":"10.23902/trkjnat.925742","DOIUrl":"https://doi.org/10.23902/trkjnat.925742","url":null,"abstract":"Biocompatible hydrogels are used in a variety of biomedical applications, including tissue scaffolds, drug delivery systems, lab/organ-on-a-chips, biosensors, cell-culture studies and contact lenses. The demand for novel and functional monomers to be used in hydrogel synthesis is increasing as the number of biomedical applications and need for biomaterials increase. The purpose of the study was to develop novel hydrogels from renewable materials. Acrylated methyl ricinoleate, a plant oil-based monomer, was used as the renewable material. The effects of acrylated methyl ricinoleate/N-isopropyl acrylamide molar ratio on hydrogel structural properties, thermal stability and in vitro cytotoxicity were studied. FTIR spectroscopy was used to characterize the structural properties of the hydrogels, while TGA was used to characterize the thermal properties. HEK293 and Cos-7 cell lines were used to test the cytotoxicity of the monomers and hydrogels. IC50 values for acrylated methyl ricinoleate and N-isopropyl acrylamide were found to be greater than 25 mg/mL. Cell viability of hydrogels containing 50% or more acrylated methyl ricinoleate was greater than 60%, while hydrogel biocompatibility decreased with decreasing molar ratio of acrylated methyl ricinoleate. Cells showed a minimum viability of 80% when incubated in hydrogel degradation products. An environmentally friendly synthesis method was developed and novel biocompatible hydrogels from renewable materials were produced for biomedical applications.","PeriodicalId":23163,"journal":{"name":"Trakya University Journal of Natural Sciences","volume":"12 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2021-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75968653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

THE ANTI HRSV ACTIVITY OF Ferula halophila Peşmen AQUEOUS AND METHANOL EXTRACT BY MTT ASSAY MTT法测定嗜盐阿魏提取物的抗HRSV活性

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Trakya University Journal of Natural Sciences Pub Date : 2021-03-22 DOI: 10.23902/TRKJNAT.805545

H. Doğan, Rüstem Duman

{"title":"THE ANTI HRSV ACTIVITY OF Ferula halophila Peşmen AQUEOUS AND METHANOL EXTRACT BY MTT ASSAY","authors":"H. Doğan, Rüstem Duman","doi":"10.23902/TRKJNAT.805545","DOIUrl":"https://doi.org/10.23902/TRKJNAT.805545","url":null,"abstract":"The trend towards natural products in the world is increasing due to the increased drug resistance of infectious diseases, the high prices for drugs and the difficulty of access. Also, bacterial or viral diseases that are difficult to treat and need a long time for proper treatment cause important infections in people. Since effective drugs could not be developed for most viral infections, it is very important to find natural products against viruses to introduce them to the world of science. The antiviral activities of the aqueous and methanol extract from Ferula halophila Pesmen, an endemic species to Turkey, has been investigated against human respiratory syncytial virus (HRSV, ATCC-VR-26). The cytotoxic and antiviral properties of plant extracts were investigated in HRSV / HEp-2 cell systems, respectively by the colorimetric MTT assay. In the study, the titer of RSV was used as 100 TCID50 (50% tissue culture infective dose). While MNTC (Maximum non-toxic concentration) of methanol extract was 195.313 µg/mL and CC50 (50% cytotoxic concentration) was 4366.22 µg/mL, it was determined as MNTC = 390.625 µg/mL and CC50 = 4366.22 for aqueous extract. According to the results, methanol extract showed more toxicity than the aqueous extract. The MNTC of Ribavirin used as a positive control was determined as 0.98 µg/mL and CC50 was 110.40 µg/mL. As a result of the study, it was determined that the methanol extract was not effective, whereas the aqueous extract had a significant anti-HRSV activity with the values of 50.69 µg/mL EC50 (50% Effective Concentration) and 97.54 Selectivity Index (SI). The EC50 and SI values of Ribavirin were 2.39 µg/mL and 46.19, respectively. According to the results, we can explain the presence of antiviral activity only in the aqueous extract and the absence in the methanol extract by the high toxicity of it and the insolubility of the antiviral compounds in the methanol extract.","PeriodicalId":23163,"journal":{"name":"Trakya University Journal of Natural Sciences","volume":"1 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2021-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90059917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Distinctive SIRE1 Retrotransposon Patterns on Barley Chromosomes? 大麦染色体上独特的SIRE1反转录转座子模式?

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Trakya University Journal of Natural Sciences Pub Date : 2020-10-09 DOI: 10.23902/trkjnat.773302

E. Karlik, N. Gozukirmizi

{"title":"Distinctive SIRE1 Retrotransposon Patterns on Barley Chromosomes?","authors":"E. Karlik, N. Gozukirmizi","doi":"10.23902/trkjnat.773302","DOIUrl":"https://doi.org/10.23902/trkjnat.773302","url":null,"abstract":": SIRE1 is an active and relatively high copy-number retroelement belongs to the Tyl/Copia long terminal repeat (LTR) retrotransposon superfamily. Distinctive SIRE1 elements ( ENV and GAG ) distributions in barley genome were observed by using fluorescent in situ hybridization (FISH). We performed PCR to obtain tetramethylrhodamine-dUTP (TRITC)-labelled probes. Localizations of SIRE1 ENV and GAG domains were demonstrated under confocal microscope on Hordeum vulgare L. cv. Hasat root preparations. Our results revealed the distributions of SIRE1 elements ENV and GAG in barley genome. These results may provide to uncover the organization of SIRE retrotransposon pattern in barley genome. Özet: SIRE1 , Tyl/Copia Uzun Uç Tekrarlı (Long Terminal Repeats- LTR) retrotranspozon üst ailesine ait olan aktif, nispeten yüksek kopyalı bir retroementtir. Arpa genomundaki ayırt edici SIRE1 elementlerinin ( ENV ve GAG ) dağılımları floresan in situ hibridizasyonu (FISH) kullanılarak gözlemlendi. Tetramethylrhodamine-dUTP (TRITC)-işaretli probların elde edilmesinde PCR gerçekleştirildi. SIRE1 ENV ve GAG domainlerinin yerleşimleri, Hordeum vulgare L. cv. Hasat kök preparatlarında konfokal mikroskobu altında gösterildi. Sonuçlarımız, arpa genomundaki SIRE1 elementlerinin ENV ve GAG dağılımlarını göstermektedir. Bu sonuçlar, SIRE1 elementlerinin arpa genomunun organizasyonunun ortaya çıkarılmasına katkı sağlayacaktır.","PeriodicalId":23163,"journal":{"name":"Trakya University Journal of Natural Sciences","volume":"33 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2020-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83107368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

USE OF MULBERRY POMACE AS SUBSTRATE FOR CITRIC ACID PRODUCTION BY Aspergillus niger MT-4 桑树渣作为黑曲霉MT-4产柠檬酸底物的研究

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Trakya University Journal of Natural Sciences Pub Date : 2020-10-02 DOI: 10.23902/trkjnat.670859

Rufina Aidynova, N. Arslan, M. Aydoğan

{"title":"USE OF MULBERRY POMACE AS SUBSTRATE FOR CITRIC ACID PRODUCTION BY Aspergillus niger MT-4","authors":"Rufina Aidynova, N. Arslan, M. Aydoğan","doi":"10.23902/trkjnat.670859","DOIUrl":"https://doi.org/10.23902/trkjnat.670859","url":null,"abstract":"Dut posasi (DP), geleneksel bir Turk yiyecegi olan pekmez'in uretiminden sonra ortaya cikan bir atik maddedir. Bu calisma, Aspergillus niger MT-4 ile sitrik asit (SA) uretimi icin DP’nin substrat olarak kullanilabilirligini test etmek icin gerceklestirilmistir. Calismada ayrica, SA uretimini artirmak icin bazi kultur kosullari da optimize edilmistir. MP’nin nem, toplam karbonhidrat, suda-cozunur karbonhidrat, protein, lipid ve kul icerikleri sirasiyla %31,1; 47,1; 1,3; 13,4; 1,8 ve 1,4 olarak belirlenmistir. Deneyler, uretim besiyerinin 100 ml’sini iceren 250 ml'lik erlenler icerisinde gerceklestirilmistir. Hem fungal biyokutle (FB) hem de SA uretimi icin optimum DP konsantrasyonu, 120 gr/lt olarak belirlenmistir. DP bazli ortama eklenen tum KH2PO4 konsantrasyonlarinin SA uretimini azalttigi fakat FB uretimini artirdigi belirlenmistir. SA uretimi icin MgSO4 ve (NH4)2SO4’un optimal konsantrasyonlari sirasiyla 1 ve 2 gr/lt olarak bulunmustur. Diger optimal parametreler, baslangic pH'si 7,0 ve inkubasyon suresi 5 gun olarak belirlenmistir. Optimize edilmis kultur kosullari altinda, uretilen SA miktari 24,6 gr/lt olarak belirlenmistir. Besinci gunde, Yp/s; Yp/x ve Yx/s sirasiyla 0,2 gr SA/gr DP; 1,43 gr SA/gr FB ve 0,14 gr FB/gr DP olarak hesaplanmistir. DP'nin SA dahil mikrobiyal metabolitlerin uretimi icin fermentasyon substrati olarak kullanilabilirligi ilk kez bu calismada test edilmistir.","PeriodicalId":23163,"journal":{"name":"Trakya University Journal of Natural Sciences","volume":"19 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2020-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76733872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

CONSERVATION STATUS OF THREE RARE AND ENDEMIC SPECIES FROM TURKEY (KALIDIUM WAGENITZII, MUSCARI ADILII AND VERBASCUM GYPSICOLA) 土耳其3种珍稀特有物种(wagenitzii kalidium、muscari adilii和verbascum gypsicola)的保护现状

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Trakya University Journal of Natural Sciences Pub Date : 2020-09-23 DOI: 10.23902/trkjnat.751851

Ali Murat Keser, G. Ayyildiz, Merve Yıldırım, A. Yaprak, G. Tug

{"title":"CONSERVATION STATUS OF THREE RARE AND ENDEMIC SPECIES FROM TURKEY (KALIDIUM WAGENITZII, MUSCARI ADILII AND VERBASCUM GYPSICOLA)","authors":"Ali Murat Keser, G. Ayyildiz, Merve Yıldırım, A. Yaprak, G. Tug","doi":"10.23902/trkjnat.751851","DOIUrl":"https://doi.org/10.23902/trkjnat.751851","url":null,"abstract":"In this study, we aimed to determine the population size and distribution areas and to re-evaluate IUCN threat categories of Kalidium wagenitzii (Aellen) Freitag & G. Kadereit, Muscari adilii M.B. Guner & H. Duman and Verbascum gypsicola Vural & Aydogdu, which are endemics of the Central Anatolia region of Turkey. The three species have limited distribution areas and high risk of extinction as a result of human impact. The perennial halophytic species K. wagenitzii was found in 5 localities around Salt Lake (Tuz Golu) and a total number of 6458 mature individuals were determined. The area of occupancy of the species is 36 km2 and the extent of occurrence is 213 km2. Uncontrolled use of water resources for agricultural purposes is a serious threat factor for the species. Kalidium wagenitzii is listed in EN category according to the IUCN Red List criteria. Muscari adilii prefers marly soils and its habitat type is formed by secondary succession after the destruction of Pinus nigra and oak forests. It is known from 3 localities around Nallihan-Beypazari with a population size of 6144 mature individuals. The area of occupancy and the extent of occurrence of the species is 12 km2 and 28 km2, respectively. The pressures on the species are road construction and increase of farmland, afforestation and factory establishment. According to the IUCN Red List criteria, the species is listed in CR category. Verbascum gypsicola is distributed on marly soils. It is known from 3 localities around Nallihan–Beypazari and one locality in Sivrihisar-Eskisehir with 2755 mature individuals in total. The area of occupancy of the species is 16 km2 and the extent of occurrence is 269 km2. Overgrazing and expansion of agricultural land, together with factory establishment are the major threats for this species, which is listed as EN in IUCN Red List.","PeriodicalId":23163,"journal":{"name":"Trakya University Journal of Natural Sciences","volume":"23 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2020-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78582103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

THE COMMERCIAL AND DISCARD CATCH RATES OF THE TRAWL FISHERY IN THE ISKENDERUN BAY (NORTHEASTERN LEVANTINE SEA) 伊斯肯德伦湾(东北黎凡特海)拖网渔业的商业捕捞率和废弃捕捞率

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Trakya University Journal of Natural Sciences Pub Date : 2020-09-18 DOI: 10.23902/TRKJNAT.773435

C. Dalyan

引用次数: 3

NOTES ON LEAF AND STEM ANATOMY OF Thlaspi Sensu Lato 标题海苔叶茎解剖注释

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Trakya University Journal of Natural Sciences Pub Date : 2020-09-16 DOI: 10.23902/TRKJNAT.762509

Cengiz Karaismailoğlu, Osman Erol

引用次数: 3

AGE, GROWTH AND OTOLITH BIOMETRY-BODY LENGTH RELATIONSHIPS OF RED BANDFISH (Cepola macrophthalma L., 1758) IN THE SEA OF MARMARA, TURKEY 土耳其马尔马拉海红带鱼(Cepola macrophthalma L.， 1758)的年龄、生长和耳石生物特征-体长关系

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Trakya University Journal of Natural Sciences Pub Date : 2020-09-11 DOI: 10.23902/trkjnat.714201

A. İşmen, M. A. İhsanoğlu, I. B. Daban, H. Inceoğlu

{"title":"AGE, GROWTH AND OTOLITH BIOMETRY-BODY LENGTH RELATIONSHIPS OF RED BANDFISH (Cepola macrophthalma L., 1758) IN THE SEA OF MARMARA, TURKEY","authors":"A. İşmen, M. A. İhsanoğlu, I. B. Daban, H. Inceoğlu","doi":"10.23902/trkjnat.714201","DOIUrl":"https://doi.org/10.23902/trkjnat.714201","url":null,"abstract":"Cepola macrophthalma (Linnaeus, 1758)’in yas, buyume ve otolit biyometri-total boy iliskileri arastirilmistir. Bireyler Mart 2012-Haziran 2014 tarihleri arasinda Marmara Denizi'nde algarna ile yakalanmistir. Bu calismada orneklenen 51,5 cm'lik C. macrophthalma bireyinin boyu, Marmara Denizi'nde bu tur icin maksimum olarak kaydedilmistir. Boy-agirlik iliskisi denklemine gore buyume tipi negatif allometrik olarak belirlenmistir (b=1,36). Otolith boyu-otolith agirligi, otolith genisligi- otolith agirligi, otolith boyu-total boy, otolith genisligi-total boy, otolit boyu-otolit genisligi, total boy-otolit agirligi iliskileri OW=0,0002*OL2,6377 (R2=0,91), OW=0,001*OWi2,6215 (R2=0,94), OL=0,057*TL+3,2087 (R2=0,57), OWi=0,0316*TL+1,8511 (R2=0,55), OWi=0,527*OL+0,2015 (R2=0,86) OW=0,0004*TL+0,0029 (R2=0,58) olarak hesaplanmistir. Yaslar 80 adet otolit okumasindan hesaplanmistir; gozlemlenen en kucuk ve en buyuk yaslar sirasiyla 1 ve 5’tir. von Bertalanffy denklemine gore hesaplanan buyume parametreleri degerleri L∞=61,95 cm, K=0,19 yil-1, t0 = -0,05 yil olarak belirlenmistir. Stogun buyuk cogunlugu (%77) genc bireylerden (1-2 yas grubu) olusmaktadir. Marmara Denizi’nde C. macrophthalma stogunun daha cok genc bireylerden olusmasi stoklarin av baskisi altinda oldugunu dusundurmektedir.","PeriodicalId":23163,"journal":{"name":"Trakya University Journal of Natural Sciences","volume":"8 1","pages":""},"PeriodicalIF":0.7,"publicationDate":"2020-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78983134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0