C. Wong, Boyu Wang, F. Wan, P. Mak, Pu Mak, M. Vai
{"title":"An improved phase-tagged stimuli generation method in steady-state visual evoked potential based brain-computer interface","authors":"C. Wong, Boyu Wang, F. Wan, P. Mak, Pu Mak, M. Vai","doi":"10.1109/BMEI.2010.5640083","DOIUrl":"https://doi.org/10.1109/BMEI.2010.5640083","url":null,"abstract":"This paper proposes an improved method for generating different phases of visual stimulus while liquid crystal display (LCD)/cathode ray tube (CRT) is employed as the visual stimulator. Since using the traditional method can only generate the limited frequencies and phases of visual stimulus, increasing the number of different flickering targets becomes very difficult in steady-state visual evoked potential (SSVEP)-based brain-computer interface (BCI). The experimental result shows that the proposed method can generate the visual stimulus with more phase angles than the traditional method. In addition, the proposed LCD visual stimulator can evoke the subject's SSVEP with expected phase.","PeriodicalId":231601,"journal":{"name":"2010 3rd International Conference on Biomedical Engineering and Informatics","volume":"254 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122171462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The research of the fault types recognition in transformer by differential protection based on LIBSVM","authors":"Hao Wu, Cheng-hua Fu, Hui Guo, Chang-zhong Chen","doi":"10.1109/BMEI.2010.5639826","DOIUrl":"https://doi.org/10.1109/BMEI.2010.5639826","url":null,"abstract":"A new method to distinguish various fault types of transformer by differential protection based on LIBSVM is discussed. This paper uses PSCAD/EMTDC to build transformer and differential protection model which is applied to simulate various transformer fault types, the simulation data and characteristic value extracted are preprocessed; then fault identification model based on LIBSVM is established. This paper finds the optimal settings by different kernel functions and parameters through a lot of experiments. Experimental results show that LIBSVM can identify various fault types correctly, it verifies the accuracy of transformer fault types recognition by differential protection based on LIBSVM.","PeriodicalId":231601,"journal":{"name":"2010 3rd International Conference on Biomedical Engineering and Informatics","volume":"122 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123972799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A new algorithm in detecting changepoint in linear regression models","authors":"Hualing Zhao, Xiaoxia Wu, Hanfeng Chen","doi":"10.1109/BMEI.2010.5639421","DOIUrl":"https://doi.org/10.1109/BMEI.2010.5639421","url":null,"abstract":"The changepoint problem in a two-phase simple linear regression model has received increasing attentions. A changepoint in copy number variations in bioinformatics and medical informatics, pattern recognitions, data mining, and many other applications, refers to a time point at which a structural pattern change occurs during a long-term experimentation process. Given a series of observations, the problem is to detect a putative changepoint in the series. Computations in detecting a changepoint is typically time-consuming and inefficient. Recently Liu and Qian (2010) proposed an interesting and computationally easy algorithm via empirical likelihood methods. In this article, a new algorithm is proposed to improve the detecting power. The new algorithm is computationally as easy as Liu and Qian's algorithm. Simulation results show that the new algorithm greatly improves the detecting powers and hit rates over Liu and Qian's algorithm.","PeriodicalId":231601,"journal":{"name":"2010 3rd International Conference on Biomedical Engineering and Informatics","volume":"101 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123975630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Sun, H. Shieh, Yi-Ching Tang, Chun-Lang Tsai, Hsin-Wei Huang, Wei-Hao Liu, Chia-Ming Liu, Jen-Wei Chang, Jia-Hao Li, C. Ching
{"title":"Design and implementation of integrated front-end readout circuit for linear-array biosensors with chopper-stabilized operational amplifier","authors":"T. Sun, H. Shieh, Yi-Ching Tang, Chun-Lang Tsai, Hsin-Wei Huang, Wei-Hao Liu, Chia-Ming Liu, Jen-Wei Chang, Jia-Hao Li, C. Ching","doi":"10.1109/BMEI.2010.5639393","DOIUrl":"https://doi.org/10.1109/BMEI.2010.5639393","url":null,"abstract":"A readout circuit for the linear array pH sensor was designed and developed, using chopper stabilization technique. It consisted of analog multiplexer, chopper stabilized operational amplifier, level shift, filter and buffer stage. The operational amplifier used in this design was a folded cascade amplifier. Results showed that the circuit can reduce input offset, drift voltage and noise. Moreover, noise can be further reduced on a faster chopper frequency. This readout circuit can be used for measuring small signal of low frequency biosensor. The readout circuit design was implemented using TSMC 0.35um 2P4M standard CMOS process.","PeriodicalId":231601,"journal":{"name":"2010 3rd International Conference on Biomedical Engineering and Informatics","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125790455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chao Ma, Ming Zhang, Cheng Tan, Chunlin Zhang, Wei Su
{"title":"Analysis of lower-limb muscle activities during whole body vibration with different standing postures","authors":"Chao Ma, Ming Zhang, Cheng Tan, Chunlin Zhang, Wei Su","doi":"10.1109/BMEI.2010.5640011","DOIUrl":"https://doi.org/10.1109/BMEI.2010.5640011","url":null,"abstract":"Based on inverse dynamics, the muscle activities and joint forces of the subject lower limb with knee normal and knee lock postures under vertical whole body vibration with the frequency of 30Hz and the acceleration of about 0.5g were analyzed using AnyBody Modeling System. Using the Motion Capture System displacements of the marked points on the lower limb were monitored during vibrating process with two different standing postures. At the same time the sEMG signals were recorded. In AnyBody Modeling System, the simplified Model of the lower limb were driven by the marked point displacements to calculate the muscle activities such as rectus femoris, gastrocnemius, etc and knee and ankle joint forces. The comparison between the experimental sEMG signals and the calculated results indicated that the model prediction is coupled with the experiments. The results also show that the vibration countermeasure could be as a physical training method to affect the musculoskeletal system and standing posture causes changes in muscle activities and joint forces during the vibrating. So when the vertical whole body vibration is used for subjects with musculoskeletal disorder, the standing posture should be considered according to the individual cases.","PeriodicalId":231601,"journal":{"name":"2010 3rd International Conference on Biomedical Engineering and Informatics","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125833426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"One novel composite nano-particles membrane modified amperometric immunosensor for Escherichia coli in polluted waters","authors":"Y. Wu, Fu-Tao Hu, Ning Gan, Tianhua Li, L. Gao","doi":"10.1109/BMEI.2010.5639388","DOIUrl":"https://doi.org/10.1109/BMEI.2010.5639388","url":null,"abstract":"A novel amperometric immunoassay for identification of Escherichia coli (E.coli) in a matrix containing zirconium dioxide nanoparticles (ZrO<inf>2</inf>) was described. Firstly, the antibody of E.coli (anti E.coli) was immobilized on a glassy carbon electrode (GCE) modified with carbon nanotubes (CNTs) using ZrO<inf>2</inf> nanoparticles, colloidal gold (Au) and poly-Lysine (pLL) composite membrane (ZrO<inf>2</inf>-Au-pLL-anti-E.coli) aiming to maintain the antibody's bioactivity. Then one novel sebacato-bridged Co(□) complex Co(suc)(bpy)(H<inf>2</inf>O)<inf>2</inf> (referred to as CoL, suc=succinic acid; bpy=2,2′-bipyridine) was adsorbed onto the surface of ZrO<inf>2</inf>-Au-pLL-anti-E.coli composite membrane, thus the immunosensor (GCE|CNTs|ZrO<inf>2</inf>-Au-pLL-anti-E.coli|CoL) for determination of E.coli was constructed based on one step immunoreaction using cyclic voltammetry (CV) method. CoL can be employed as an electron transfer mediator for catalytic activity detection of H<inf>2</inf>O<inf>2</inf>. After the immunosensor was incubated with E.coli solution at room temperature for 20 min, the electron transfer access of CoL to H<inf>2</inf>O<inf>2</inf> was partly inhibited, which leads to a linear decrease of the catalytic efficiency to H<inf>2</inf>O<inf>2</inf>. The immunosensor was employed to determine E.coli in samples and the results were consistent to the tradition enzyme-linked immunosorbent assays (ELISA) method. The proposed ampero metric immunosensor was sensitive, quick and disposable, which was suitable for determination of E.coli in polluted waters for public health and environmental protection.","PeriodicalId":231601,"journal":{"name":"2010 3rd International Conference on Biomedical Engineering and Informatics","volume":"71 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124625846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"VPRS based on similar relation in incomplete information system","authors":"Shibao Sun, Aiping Ding, Chengxiang Hu","doi":"10.1109/BMEI.2010.5639837","DOIUrl":"https://doi.org/10.1109/BMEI.2010.5639837","url":null,"abstract":"Through changing the equivalence relation to the similar relation in incomplete information system, a new variable precision rough set model and an approach for knowledge reduction are proposed. The basic properties of lower and upper approximation operators are also investigated. Finally, the example proves that the new variable precision rough set model can effectively reduct database, roundly wide application range of the VPRS, and fully maintain information for database in incomplete information system.","PeriodicalId":231601,"journal":{"name":"2010 3rd International Conference on Biomedical Engineering and Informatics","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124823448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Antibody immobilization for biosensing on gold-coated magnetite nanoparticles surface","authors":"Quanguo He, Lei Zeng, Zhaohui Wu","doi":"10.1109/BMEI.2010.5639598","DOIUrl":"https://doi.org/10.1109/BMEI.2010.5639598","url":null,"abstract":"Surface gold coverage of Fe3O4 nanoparticles were prepared and approved by various characterizations. The saturation magnetization of the gold-coated nanoparticles remains almost unchanged (less than 1 emu·g−1) for long storage periods more than 2 months. Then the antibody immobilization for biosensor application was conducted and compared with colloidal gold nanoparticles and parent magnetite nanoparticles. The antibody immobilization yield of these nanoparticle surfaces were investigated in terms of ELISA (Enzyme-Linked Immunosorbent Assay). The gold-coated magnetite nanoparticles demonstrated a best immobilization; such endurability under biochemical environment enabled themselves as promising carriers for biosensor applications.","PeriodicalId":231601,"journal":{"name":"2010 3rd International Conference on Biomedical Engineering and Informatics","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129402083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Functional neuroimaging studies of Chinese character and pure tone processing for language education","authors":"Xiujun Li, Qiyong Guo, Jinglong Wu","doi":"10.1109/BMEI.2010.5639481","DOIUrl":"https://doi.org/10.1109/BMEI.2010.5639481","url":null,"abstract":"Functional magnetic resonance imaging (fMRI) was used to map brain activation during visual language task. As the result, educations have implications for other cognitive ability as well as language skill. There have no data related to different during Chinese auditory word processing in literate and illiterate subject. In this study, we analyzed data based on fMRI experimental to examine the effects of education on brain activation associated with language and control tasks in 26 healthy right-handed Chinese subjects (13 literates and 13 illiterates).There were 36 pairs of Chinese auditory word in the language task and 36 pairs of pure tone in the control task. When we compared literate and illiterate subjects, we observed education-related differences in activation patterns. As the result, we discovered bilateral different brain activations in the bilateral middle frontal gyrus (BA6), the right middle occipital gyrus (BA32), the right inferior frontal gyrus (BA47), the right middle temporal gyrus (BA21), the right superior temporal gyrus (BA22), the bilateral middle frontal gyrus (BA9) and cerebellum. Conclusion that education have implications for other cognitive ability as well as language processing, literate might respond in these task more accuracy and quickly than illiterate.","PeriodicalId":231601,"journal":{"name":"2010 3rd International Conference on Biomedical Engineering and Informatics","volume":"95 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129718411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Uncovering disease regions using pseudo time-series trajectories on clinical trial data","authors":"Yuanxi Li, A. Tucker","doi":"10.1109/BMEI.2010.5639726","DOIUrl":"https://doi.org/10.1109/BMEI.2010.5639726","url":null,"abstract":"We build pseudo time-series from cross sectional data using a combination of distance metrics, graph theoretical operations and resampling methods. In this paper we explore some extensions of these ideas in order to automatically identify disease regions of interest at key junctions and ‘extreme’ ends of the trajectories. We test these on a number of different medical datasets, in order to explore how applicable the approach is to disease models in general. We focus on two issues in this study: firstly, how to build time-series models from cross-sectional data, and secondly how to automatically identify different disease states along these trajectories, along with the transitions between them. Our results on synthetic data show how the hidden transitional states can indeed be discovered from cross-sectional data and demonstrate the power of the approach on real-world datasets for Glaucoma, Parkinson's Disease and Breast Cancer.","PeriodicalId":231601,"journal":{"name":"2010 3rd International Conference on Biomedical Engineering and Informatics","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2010-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129868273","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}