Topics in companion animal medicine最新文献

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Pathological findings, KIT expression, and clinical course of cutaneous mast cell tumours in pet Syrian hamsters (Mesocricetus auratus) 宠物叙利亚仓鼠(Mesocricetus auratus)皮肤肥大细胞肿瘤的病理表现、KIT表达和临床病程
IF 1.3 3区 农林科学
Topics in companion animal medicine Pub Date : 2026-01-01 Epub Date: 2025-12-22 DOI: 10.1016/j.tcam.2025.101041
Hirotaka Kondo , Iori Koizumi , Saki Kawahara , Tomosige Baba
{"title":"Pathological findings, KIT expression, and clinical course of cutaneous mast cell tumours in pet Syrian hamsters (Mesocricetus auratus)","authors":"Hirotaka Kondo ,&nbsp;Iori Koizumi ,&nbsp;Saki Kawahara ,&nbsp;Tomosige Baba","doi":"10.1016/j.tcam.2025.101041","DOIUrl":"10.1016/j.tcam.2025.101041","url":null,"abstract":"<div><div>This report describes the histopathological and immunohistochemical features, as well as the biological behaviour, of cutaneous mast cell tumours for the first time in two Syrian hamsters. Both cases presented with a raised cutaneous mass, one in the preputial region and one on the ear pinna, respectively. The masses showed similar histological and immunohistochemical findings and were composed of solid sheets of round cells with moderate amounts of basophilic intracytoplasmic granules. These granules showed prominent metachromasia on toluidine blue staining. Immunohistochemically, the neoplastic cells had diffuse, granular cytoplasmic labelling to anti-KIT antibody. There was no evidence of recurrence in both cases, and no metastatic lesions were observed in Case 1 on necropsy and subsequent histopathological examination, suggesting that, compared with other animals, mast cell tumours have a benign clinical course in Syrian hamsters during the initial follow-up period.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"70 ","pages":"Article 101041"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145828956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
“Hepatometry in young and adult domestic cats using ultrasound” “用超声波测量幼年和成年家猫的肝脏”。
IF 1.3 3区 农林科学
Topics in companion animal medicine Pub Date : 2026-01-01 Epub Date: 2025-12-03 DOI: 10.1016/j.tcam.2025.101027
Acacia Rebello Coutinho, Carolina Costa Cardoso, Mariah Gois Ceregatti, Rossana Priscilla de Souza Figueira, Fabiola de Oliveira Paes Leme, Anelise Carvalho Nepomuceno
{"title":"“Hepatometry in young and adult domestic cats using ultrasound”","authors":"Acacia Rebello Coutinho,&nbsp;Carolina Costa Cardoso,&nbsp;Mariah Gois Ceregatti,&nbsp;Rossana Priscilla de Souza Figueira,&nbsp;Fabiola de Oliveira Paes Leme,&nbsp;Anelise Carvalho Nepomuceno","doi":"10.1016/j.tcam.2025.101027","DOIUrl":"10.1016/j.tcam.2025.101027","url":null,"abstract":"<div><div>The liver plays a vital role in the body, including the secretion of bile and the metabolism of lipids and carbohydrates. Its evaluation is crucial for assessing patient health. In cats, liver disorders often alter organ size and structure. Abdominal ultrasound is a safe and widely accessible tool in veterinary practice, and it is key to assessing liver morphology, although its interpretation remains subjective. This study aimed to establish a standardized method for measuring the liver of cats and determine reference values for healthy young and adult animals. Clinically healthy cats without laboratory or ultrasound signs of hepatobiliary disease were included. Radiographic parameters from the literature were applied to confirm normal liver dimensions. The cats were divided into two groups according to their body condition scores: 20 with an ideal weight (Group 1) and 20 that were overweight or obese (Group 2). Standardized planes were defined for the left and right hepatic lobes. Measurements were taken three times per lobe to calculate the mean distance from the diaphragmatic surface to the caudal border of the liver. Groups 1 and 2 did not differ significantly in their results. However, males presented higher overall mean values than females, and the left lobe was consistently longer than the right lobe. The established reference values were based on sex and lobe: in males, left lobe 3.46 ± 1.23 cm, right lobe 2.80 ± 0.88 cm; in females, left lobe 3.12 ± 1.05 cm, right lobe 2.57 ± 0.97 cm. Further studies are needed to validate ultrasonographic hepatometry and refine parameters for use in animals with liver disease.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"70 ","pages":"Article 101027"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145688868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of a lidocaine with epinephrine infusion for reducing postoperative pain and complications in elective cat castrations 利多卡因与肾上腺素输注对减少择期猫阉割术后疼痛和并发症的评价。
IF 1.3 3区 农林科学
Topics in companion animal medicine Pub Date : 2026-01-01 Epub Date: 2025-12-25 DOI: 10.1016/j.tcam.2025.101043
James Mack Fudge , Seong Eun Cho , Bernie Page , Inhyung Lee
{"title":"Evaluation of a lidocaine with epinephrine infusion for reducing postoperative pain and complications in elective cat castrations","authors":"James Mack Fudge ,&nbsp;Seong Eun Cho ,&nbsp;Bernie Page ,&nbsp;Inhyung Lee","doi":"10.1016/j.tcam.2025.101043","DOIUrl":"10.1016/j.tcam.2025.101043","url":null,"abstract":"<div><div>This prospective, randomized, blinded clinical trial evaluated whether infusing lidocaine with epinephrine (LE) into spermatic cords during elective feline surgical castrations improved postoperative pain control and reduced acute postoperative complications. Five hundred one apparently healthy male cats presenting for elective surgical gonadectomy to a non-for-profit high-volume spay and neuter practice were entered into the study. Cats were a combination of feral, shelter-owned, and client-owned. Cats were anesthetized using a standardized, multimodal protocol that included buprenorphine, ketamine, dexmedetomidine. Cats were randomized to receive a LE infusion or no local treatment. A Simple Descriptive Scale (SDS) was used to assess acute postoperative pain at 1 and 3 h post-anesthesia recovery, and postoperative surgery-associated complications (swelling, bruising, and/or bleeding) were recorded prior to a same-day discharge from the hospital. The duration of anesthesia recovery and the quality of the recovery (pleasant, acceptable, or unpleasant) were also evaluated.</div><div>No significant differences were observed between groups in pain scores, early complication rates, or subjective assessments of anesthesia recovery quality. Recovery durations were shorter in the LE group, although the clinical relevance of this difference (&lt;1 min) is uncertain. Overall complication incidence and pain scores were low across groups.</div><div>These findings suggest that, under conditions of experienced surgical technique and standardized multimodal anesthesia, LE infusion does not confer any additional, significant, measurable, clinically relevant benefits in the acute postoperative period. Future studies should incorporate validated feline pain scales and longer follow-up periods, including the post-discharge period, to better evaluate the potential effects on postoperative pain and complications.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"70 ","pages":"Article 101043"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145846900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microfilaruria of morphologically identified Dirofilaria repens and Brugia spp. in one cat and two dogs: Case series 在1只猫和2只狗中形态学鉴定的重丝虫和布鲁贾丝虫微丝虫病:病例系列。
IF 1.3 3区 农林科学
Topics in companion animal medicine Pub Date : 2026-01-01 Epub Date: 2025-12-23 DOI: 10.1016/j.tcam.2025.101042
Keerthana Santhosh , P. Preena , Sherin B. Sarangom , Y Ajith , Nongthombam Boby , Usha Narayana Pillai , S Ajithkumar , PV Tresamol
{"title":"Microfilaruria of morphologically identified Dirofilaria repens and Brugia spp. in one cat and two dogs: Case series","authors":"Keerthana Santhosh ,&nbsp;P. Preena ,&nbsp;Sherin B. Sarangom ,&nbsp;Y Ajith ,&nbsp;Nongthombam Boby ,&nbsp;Usha Narayana Pillai ,&nbsp;S Ajithkumar ,&nbsp;PV Tresamol","doi":"10.1016/j.tcam.2025.101042","DOIUrl":"10.1016/j.tcam.2025.101042","url":null,"abstract":"<div><div>Microfilaruria is an uncommon parasitological finding in veterinary practice. This report describes three clinically distinct cases of microfilaruria in companion animals from Kerala, India, an endemic region for canine filariasis. Case 1 involved a dog with dual infection by morphologically identified <em>Dirofilaria repens</em> and <em>Brugia</em> spp., associated with hemorrhagic cystitis and hypermicrofilaremia. Case 2 involved a diabetic dog with <em>E. coli</em> urinary tract infection, in which microfilariae were detected in the urine sediment, likely due to glycosuria-induced epithelial compromise. This represents the first documented case of microfilaruria in a dog with concurrent diabetes mellitus. Case 3 documented the first reported occurrence of microfilaruria due to <em>D. repens</em> in a cat, which was likely triggered by trauma-induced urethral obstruction. All cases were managed with targeted therapy based on the primary diagnosis, combining anthelmintics, antibiotics, supportive care, and metabolic regulation. These cases suggest that microfilaruria may occur via various mechanisms, including inflammation-induced uroepithelial disruption, glomerular leakage, or local trauma. Molecular confirmation (e.g., PCR) was not performed; hence, definitive differentiation between <em>D. repens</em> and <em>D. asiatica</em> was challenging and represents a limitation of this study. The paper emphasizes the critical importance of routine, thorough urine sediment examination, even in atypical species like cats, and in animals with concurrent systemic or metabolic disorders. Early recognition of such unusual presentations may aid in timely intervention and broaden our understanding of filarial infections in veterinary clinical practice.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"70 ","pages":"Article 101042"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145835879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Seroprevalence of Dirofilaria Immitis and assessment of systemic inflammatory indexes in apparently healthy dogs from coastal northeastern Brazil 巴西东北部沿海地区表面健康犬的免疫双丝虫血清患病率及全身炎症指标评估。
IF 1.3 3区 农林科学
Topics in companion animal medicine Pub Date : 2026-01-01 Epub Date: 2025-11-26 DOI: 10.1016/j.tcam.2025.101028
Naianne Araújo Félix , Aldo Severino da Silva Neto , Emanueli Maria Freitas Rodrigues , Adam Leal-Lima , Diana Célia Sousa Nunes-Pinheiro , Tiago Cunha Ferreira
{"title":"Seroprevalence of Dirofilaria Immitis and assessment of systemic inflammatory indexes in apparently healthy dogs from coastal northeastern Brazil","authors":"Naianne Araújo Félix ,&nbsp;Aldo Severino da Silva Neto ,&nbsp;Emanueli Maria Freitas Rodrigues ,&nbsp;Adam Leal-Lima ,&nbsp;Diana Célia Sousa Nunes-Pinheiro ,&nbsp;Tiago Cunha Ferreira","doi":"10.1016/j.tcam.2025.101028","DOIUrl":"10.1016/j.tcam.2025.101028","url":null,"abstract":"<div><div><em>Dirofilaria immitis</em> is a vector-borne zoonotic parasite of considerable veterinary and public health significance. This study aimed to determine the seroprevalence of <em>D. immitis</em> and investigate associated hematological and inflammatory changes in clinically healthy dogs from the coastal municipalities of Beberibe and Cascavel, Ceará, Brazil. Between November 2024 and March 2025, blood samples were collected from 100 clinically healthy dogs (72 from Beberibe and 28 from Cascavel). Diagnostic testing included immunochromatographic assays for <em>D. immitis</em> antigens and microscopic evaluation for circulating microfilariae. Seropositivity for <em>D. immitis</em> was detected in 17 % of dogs, while microfilariae were identified in 7 %, including one discordant case (microfilaremic but antigen-negative). Hematological analysis revealed significantly reduced lymphocyte counts (<em>p</em> &lt; 0.01) and elevated total plasma protein concentrations (<em>p</em> &lt; 0.05) in <em>D. immitis</em>-positive animals. Furthermore, the platelet-to-lymphocyte ratio (PLR) was significantly increased in infected dogs (<em>p</em> &lt; 0.05), whereas neutrophil counts and other systemic inflammatory indices (NLR, SII, SIRI) exhibited non-significant upward trends. These findings indicate the silent circulation of <em>D. immitis</em> among clinically healthy dogs and point to early hematological and immune system alterations. Notably, the elevation of PLR may serve as a potential biomarker for subclinical immune-vascular involvement in heartworm disease. The study underscores the importance of continued regional surveillance and vector control measures to reduce the risk of zoonotic transmission.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"70 ","pages":"Article 101028"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145644348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oral glutamine supplementation in dogs infected with canine parvovirus type 2 犬细小病毒2型感染犬口服谷氨酰胺的研究
IF 1.3 3区 农林科学
Topics in companion animal medicine Pub Date : 2026-01-01 Epub Date: 2025-12-05 DOI: 10.1016/j.tcam.2025.101040
Alice Madeira Campos Melo , Victoria Ghedin , Felipe Saab Romano , Santos Natalia Ribeiro dos , Lara Alice Pagura Pellegri , Ricardo Shoiti Ichikawa , Maria Fernanda Hussni , Antonio Carlos Paes , Priscylla Tatiana Chalfun Guimarães-Okamoto , Sheila Canevese Rahal , Alessandra Melchert
{"title":"Oral glutamine supplementation in dogs infected with canine parvovirus type 2","authors":"Alice Madeira Campos Melo ,&nbsp;Victoria Ghedin ,&nbsp;Felipe Saab Romano ,&nbsp;Santos Natalia Ribeiro dos ,&nbsp;Lara Alice Pagura Pellegri ,&nbsp;Ricardo Shoiti Ichikawa ,&nbsp;Maria Fernanda Hussni ,&nbsp;Antonio Carlos Paes ,&nbsp;Priscylla Tatiana Chalfun Guimarães-Okamoto ,&nbsp;Sheila Canevese Rahal ,&nbsp;Alessandra Melchert","doi":"10.1016/j.tcam.2025.101040","DOIUrl":"10.1016/j.tcam.2025.101040","url":null,"abstract":"<div><div>This study aimed to assess the impact of oral glutamine supplementation in dogs infected with Canine Parvovirus Type 2 (CPV-2). The dogs were randomly divided into two groups: Group 1 (<em>n</em> = 10) received glutamine supplementation (500 mg/kg/day), and <em>ad libitum</em> feeding; Group 2 (control) (<em>n</em> = 10) received a placebo and <em>ad libitum</em> feeding. Group 1 dogs were significantly younger (mean 3.5 ± 0.5 months) than those in Group 2 (mean 6.3 ± 3.0 months; <em>p</em> = 0.036). Data from the two groups were compared at the hospital admission and discharge. No significant differences were observed between groups in body weight, physical examination parameters, body condition score, and muscle condition score at hospital admission. Group 1 had lower albumin levels than Group 2 at the initial assessment. The two groups had no difference in the number of days until the start of spontaneous feeding. No significant differences were observed between the groups regarding days until clinical improvement and duration of hospitalization. However, Group 1 had a shorter duration of diarrhea (mean of 2.4 days) compared to Group 2 (mean of 4.9 days) and a better fecal score, (median 5 in Group 1; median 6.5 in Group 2). In Group 2, mortality was 10 % (1 animal), while there were no deaths in Group 1. Glutamine supplementation was beneficial in dogs with CPV-2, reducing the duration of diarrhea and improving fecal score. In conclusion, glutamine shows promise as an adjunctive treatment in the treatment of dogs with CPV-2 and warrants further investigation.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"70 ","pages":"Article 101040"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145703641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Free and nanoencapsulated meloxicam as an adjuvant in intraoperative and postoperative analgesia in bicthes undergoing ovariohysterectomy 游离和纳米胶囊美洛昔康在卵巢子宫切除术患者术中及术后镇痛中的辅助作用。
IF 1.3 3区 农林科学
Topics in companion animal medicine Pub Date : 2026-01-01 Epub Date: 2025-11-24 DOI: 10.1016/j.tcam.2025.101026
Gabriela Lugoch , Jorge Abrão Pinto Vilela , Giovanna Bauer , Helloine Mariane Ribeiro Antunes , Flávia Elizabete Guerra Teixeira , Sandra Elisa Haas , Diego Vilibaldo Beckmann , Marília Teresa de Oliveira
{"title":"Free and nanoencapsulated meloxicam as an adjuvant in intraoperative and postoperative analgesia in bicthes undergoing ovariohysterectomy","authors":"Gabriela Lugoch ,&nbsp;Jorge Abrão Pinto Vilela ,&nbsp;Giovanna Bauer ,&nbsp;Helloine Mariane Ribeiro Antunes ,&nbsp;Flávia Elizabete Guerra Teixeira ,&nbsp;Sandra Elisa Haas ,&nbsp;Diego Vilibaldo Beckmann ,&nbsp;Marília Teresa de Oliveira","doi":"10.1016/j.tcam.2025.101026","DOIUrl":"10.1016/j.tcam.2025.101026","url":null,"abstract":"<div><div>Nanocarriers have the ability to increase the bioavailability of drugs, decreasing the necessary dose and adverse effects. This prospective clinical study aimed to assess the efficacy of analgesia provided by free meloxicam and nanoencapsulated meloxicam during both the intraoperative and postoperative phases of ovariohysterectomy (OH) in female dogs. Twenty healthy dogs were randomly allocated to the FM group (free meloxicam - 0.2 mg/kg) or to the MNano group (meloxicam loaded-nanocapsules - 0.2 mg/kg). Both groups received the formulations orally four hours before the surgical procedure. During the OH surgeries, intraoperative analgesia was measured using elevated heart rate and mean arterial pressure. The pain after surgery was measured using the short form of the Glasgow Composite Pain Scale and Visual Analog Scale in the first 48 hours. Platelet function was measured through a buccal mucosal bleeding time test before meloxicam administration, four hours after that administration, at the end of the OH, and 12 hours after taking the medication. In addition, creatinine was measured preoperatively, 24 and 48 hours after meloxicam administration. The distribution of rescue analgesia in the intraoperative period showed no difference between groups. No patient required supplemental analgesia in the postoperative period. There was no difference between groups in postoperative pain assessment scales, buccal mucosal bleeding time, or creatinine. However, three dogs of the FM group presented vomiting (2/10) and faecal constipation followed by haematochezia (1/10). Both free meloxicam and the new formulation of nano-encapsulated meloxicam promoted satisfactory postoperative analgesia in healthy dogs submitted to OH when administered orally, in a single dose, four hours before the surgical procedure. Only animals treated with free meloxicam had side effects related to the gastrointestinal tract in the postoperative period, indicating that the nanostructured formulation may be is safe and effective as an alternative to commercial products.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"70 ","pages":"Article 101026"},"PeriodicalIF":1.3,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145644319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful treatment of a dog with a severe Babesia vulpes infection and associated haemophagocytic syndrome after splenectomy 成功治疗一只狗与严重巴贝斯虫感染和相关的噬血细胞综合征脾切除术后。
IF 1.3 3区 农林科学
Topics in companion animal medicine Pub Date : 2025-11-01 Epub Date: 2025-11-20 DOI: 10.1016/j.tcam.2025.101025
Yordan Fernández , María C. Luna , Marcos Fernández , Antonio Meléndez-Lazo
{"title":"Successful treatment of a dog with a severe Babesia vulpes infection and associated haemophagocytic syndrome after splenectomy","authors":"Yordan Fernández ,&nbsp;María C. Luna ,&nbsp;Marcos Fernández ,&nbsp;Antonio Meléndez-Lazo","doi":"10.1016/j.tcam.2025.101025","DOIUrl":"10.1016/j.tcam.2025.101025","url":null,"abstract":"<div><div>A 12-year-old female, neutered, crossbreed dog was diagnosed by its primary care practice with severe <em>Babesia vulpes</em> infection, based on positive PCR testing, three weeks after elective splenectomy for splenic nodules identified on abdominal ultrasound. Despite treatment with standard antiprotozoal therapy, glucocorticoids, and three blood transfusions, anaemia persisted, becoming non-regenerative and prompting referral. Upon presentation, the dog exhibited pale mucous membranes and was hyperthermic. Blood tests revealed a regenerative anaemia, thrombocytopenia, hyperbilirubinaemia, hypertriglyceridaemia, hyperferritinaemia and elevated liver enzyme activity. Coombs’ testing was negative, and thoracic and abdominal imaging were unremarkable. A repeated <em>Babesia vulpes</em> PCR was positive and screening for other infectious diseases was negative. Bone marrow cytology and histopathology showed generalised hyperplasia, with macrophages comprising ≥3% of the total nucleated cells. These macrophages displayed prominent erythrophagia and, to a lesser extent, engulfment of mature neutrophils, platelets, and nucleated red blood cells. Therefore, a diagnosis of haemophagocytic syndrome associated with a severe <em>Babesia vulpes</em> infection was made. The dog received double immunosuppressive therapy, a combination of antiprotozoal drugs and a further three blood transfusions. The thrombocytopenia quickly resolved, with the anaemia improving ten days later. The antiprotozoal and immunosuppressive therapies were eventually discontinued without relapse of the babesiosis and repeated <em>Babesia vulpes</em> PCR testing was negative. To the authors’ knowledge, this is the first report to describe the successful treatment of a splenectomised dog with severe <em>Babesia vulpes</em> infection complicated by haemophagocytic syndrome.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"69 ","pages":"Article 101025"},"PeriodicalIF":1.3,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145582760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful physiotherapy management of a geriatric dog with femoral head ostectomy (FHNO) and concurrent posterior contralateral limb amputation 老年犬股骨头截骨术并发后对侧肢体截肢的物理治疗成功。
IF 1.3 3区 农林科学
Topics in companion animal medicine Pub Date : 2025-11-01 Epub Date: 2025-09-27 DOI: 10.1016/j.tcam.2025.101022
Mădălina Florina Gherman Dragomir , Anita Fehér , Iosif Vasiu , Daniela Neagu , William McCartney , Ciprian Andrei Ober
{"title":"Successful physiotherapy management of a geriatric dog with femoral head ostectomy (FHNO) and concurrent posterior contralateral limb amputation","authors":"Mădălina Florina Gherman Dragomir ,&nbsp;Anita Fehér ,&nbsp;Iosif Vasiu ,&nbsp;Daniela Neagu ,&nbsp;William McCartney ,&nbsp;Ciprian Andrei Ober","doi":"10.1016/j.tcam.2025.101022","DOIUrl":"10.1016/j.tcam.2025.101022","url":null,"abstract":"<div><div>The current case aims to report the physiotherapy management and long-term outcomes of femoral head and neck ostectomy (FHNO) performed on a geriatric dog with pelvic-contralateral limb amputation. A 10-year-old, 36 kg mixed-breed castrated male dog with an amputated left hind limb was referred to our department for pain and lameness in the right hind limb. The dog was diagnosed with end-stage hip osteoarthritis (OA) and required an FHNO, as total hip replacement (THR) was not pursued due to financial constraints. Two weeks after the surgical intervention, the dog was still experiencing difficulty moving without support. Therefore, a physiotherapy protocol was initiated, consisting of weekly hydrotherapy sessions to promote muscle growth and strength, zonal laser therapy to manage joint pain, and systemic administration of nonsteroidal anti-inflammatory drugs (NSAIDs), nutraceutical joint supplements, and oral cannabis oil. Hydrotherapy was associated with a 5 cm increase in thigh circumference after eight sessions, indicating improved muscle mass and strength. After two months of physiotherapy, the dog showed considerable improvement and was able to walk independently. The owner was pleased with the long-term outcome. Physiotherapy led to positive clinical outcomes, including improved muscle strength and gait, with a favorable prognosis after 14 months of follow-up. Physiotherapy should be considered in dogs with severe hip OA managed by FHNO when the contralateral pelvic limb is amputated.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"69 ","pages":"Article 101022"},"PeriodicalIF":1.3,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145194215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The effect of total ultrasound time, average ultrasonic power, and effective phacoemulsification time on post-operative outcomes in dogs undergoing phacoemulsification surgery 超声总时间、平均超声功率和有效超声乳化时间对超声乳化手术犬术后疗效的影响
IF 1.3 3区 农林科学
Topics in companion animal medicine Pub Date : 2025-11-01 Epub Date: 2025-08-26 DOI: 10.1016/j.tcam.2025.101010
Iro Evangelia Vlachomitrou, Saffron Dholakia, Oliver Joe Williams, Roser Tetas Pont, Charlotte Dawson
{"title":"The effect of total ultrasound time, average ultrasonic power, and effective phacoemulsification time on post-operative outcomes in dogs undergoing phacoemulsification surgery","authors":"Iro Evangelia Vlachomitrou,&nbsp;Saffron Dholakia,&nbsp;Oliver Joe Williams,&nbsp;Roser Tetas Pont,&nbsp;Charlotte Dawson","doi":"10.1016/j.tcam.2025.101010","DOIUrl":"10.1016/j.tcam.2025.101010","url":null,"abstract":"<div><h3>Purpose</h3><div>To investigate the relationship between UST (total ultrasound time), AVG (average ultrasonic power) and EPT (effective phacoemulsification time) with visual outcome and the most common surgery-related complications post phacoemulsification. Additionally to identify whether postoperative intraocular pressure (IOP) was significantly different between visual and non-visual eyes.</div></div><div><h3>Methods</h3><div>Medical records of patients undergoing phacoemulsification surgery between 2018 and 2024 were reviewed. Patients were included if UST, AVG and EPT were recorded, and data were available for six months postoperatively. Ultrasound time, AVG and EPT were compared with the number of postoperative complications, presence/absence of any complications and presence/absence of the most common individual complications at each timepoint. Additionally, EPT was compared in diabetic versus all other cataracts; a general linear mixed model approach was used for the statistical analysis. A permutation approach was used for analysis of IOPs by vision status.</div></div><div><h3>Results</h3><div>There was a significant relationship between higher number of complications and higher UST (p=0.017) and EPT (p=0.001) in the first week postoperatively. At one month postoperatively, there was no significant relationship between UST, AVG or EPT and the number of complications. However, when comparing dogs with and without complications, UST (p=0.032) and EPT (p=0.019) were significantly higher in eyes with complications. The non-visual eyes had significantly higher UST and EPT at the one and six months, respectively. Between the end of the first month and up to six months postoperatively 158 (86.4%) eyes were visual. At all time points, non-visual eyes had significantly higher IOP. Diabetic cataracts required significantly lower EPT.</div></div><div><h3>Conclusion</h3><div>Increases in UST and EPT are associated with higher numbers of complications at one week postoperatively. Eyes that developed complications at one month postoperatively are associated with higher UST and EPT.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"69 ","pages":"Article 101010"},"PeriodicalIF":1.3,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144916822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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