Topics in companion animal medicine最新文献

{"title":"Giant mammary fibroadenoma in four female dogs","authors":"Marina Possa dos Reys,&nbsp;Carolina Gonçalves de Sousa,&nbsp;Tatiane Caroline Fernandes Santana,&nbsp;Karen Yumi Ribeiro Nakagaki,&nbsp;Geovanni Dantas Cassali","doi":"10.1016/j.tcam.2026.101077","DOIUrl":"10.1016/j.tcam.2026.101077","url":null,"abstract":"<div><div>Fibroadenoma is a benign neoplasm with high prevalence in women but is rare in dogs. Its giant variant is defined by the lesion’s size (exceeding 5 cm) and weight. The standard treatment is surgical excision. The objective of this study was to demonstrate that the subclassification of giant fibroadenoma, as described in humans, can also be observed in female dogs, as evidenced by four cases analyzed. The evaluation comprised macroscopic examination and histopathological analysis, underscoring the importance of differential diagnosis and the characterization of this condition in the canine species.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"72 ","pages":"Article 101077"},"PeriodicalIF":1.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148214154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiographic evaluation of abdominal wall herniation in budgerigars (MELOPSITTACUS UNDULATUS)","authors":"Üzeyir Yiğit Uysal,&nbsp;Ebuderda Günay,&nbsp;Serhat Özsoy,&nbsp;Ozan Gündemir,&nbsp;Tomasz Szara","doi":"10.1016/j.tcam.2026.101091","DOIUrl":"10.1016/j.tcam.2026.101091","url":null,"abstract":"<div><div>This retrospective descriptive study evaluated the radiographic features of abdominal wall herniation in 72 budgerigars (Melopsittacus undulatus) presented with abdominal or caudoventral coelomic distension, abnormal abdominal contour, or suspected protrusion of coelomic contents. The study population consisted of 71 females and 1 male; age was available for 65 birds, ranging from 2 to 8 years. All birds underwent plain radiographic examination, followed by contrast-enhanced radiography after oral administration of iohexol at 1 mL per bird, corresponding to 300 mg iodine per bird. Radiographic assessment focused on the location and contour of the protruded abdominal wall region, suspected herniated contents, gastrointestinal contrast filling patterns, suspected free fluid or localized gas accumulation, mineralized egg-related material, overlying skin and subcutaneous tissue thickening, and associated skeletal findings. Polyostotic hyperostosis was recorded in 49 of 72 birds (68.1%), and mineralized material compatible with egg-related remnants was identified in 10 of 72 birds (13.9%). The herniation was recorded as ventral or ventrocaudal in 40 birds (55.6%) and dorsocaudal or perineal in 4 birds (5.6%); location was not clearly recorded in 28 birds (38.9%). Contrast-enhanced radiography improved visualization of gastrointestinal involvement, particularly intestinal loops, and helped differentiate contrast-filled intestinal segments from adjacent soft tissue or non-gastrointestinal components. In selected cases, ultrasonography provided additional diagnostic value by helping differentiate fluid-filled or cystic structures when radiographic findings were inconclusive. Overall, this study provides an imaging-based descriptive reference for assessing abdominal wall herniation in budgerigars and highlights the practical value of plain and contrast-enhanced radiography as well as complementary ultrasonography for clinical assessment and preoperative planning.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"72 ","pages":"Article 101091"},"PeriodicalIF":1.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148703340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In vitro evaluation of temperature-dependent stability and antimicrobial activity of reconstituted cefovecin sodium","authors":"Toshiharu Fukayama,&nbsp;Michio Iwahana,&nbsp;Hidetoshi Yamada,&nbsp;Lina Hamabe","doi":"10.1016/j.tcam.2026.101080","DOIUrl":"10.1016/j.tcam.2026.101080","url":null,"abstract":"<div><div>Cefovecin sodium is a long-acting third-generation cephalosporin widely used in dogs and cats. After reconstitution, refrigerated storage for a limited period is recommended; however, experimental data regarding the effects of alternative controlled storage temperatures on drug stability and antimicrobial activity are limited. This study evaluated, under in vitro conditions, the impact of storage temperature on the physicochemical stability and antimicrobial activity of reconstituted cefovecin sodium. Samples were stored at room temperature (25 ± 2°C), refrigerated conditions (4°C), or frozen conditions (-20°C) for up to 12 weeks. Visual appearance, absorbance at 360 nm, minimum inhibitory concentrations (MICs) against <em>E. coli</em> and Staphylococcus aureus, and cefovecin sodium concentrations determined by liquid chromatography–tandem mass spectrometry (LC-MS/MS) were assessed over time. Room temperature storage resulted in progressive discoloration, increased absorbance, elevated MIC values, and a significant decrease in drug concentration at later time points. Refrigerated storage delayed these changes, although mild increases in absorbance and MIC values were descriptively observed at later time points. In contrast, frozen storage preserved physicochemical properties, antimicrobial activity, and measured drug concentrations throughout the study period. These findings demonstrate that storage temperature influences the stability and in vitro antimicrobial activity of reconstituted cefovecin sodium in a condition-dependent manner. The results provide experimental reference data under controlled laboratory conditions and do not support clinical use outside the manufacturer’s approved storage instructions.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"72 ","pages":"Article 101080"},"PeriodicalIF":1.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148213459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electrochemotherapy with carboplatin and bleomycin associated with mastectomy in cats with mammary carcinoma: A pilot study","authors":"Renata Regadas,&nbsp;Graziela Souza Dias,&nbsp;Carlos Henrique Maciel Brunner,&nbsp;Vitor de Moraes Pina de Carvalho,&nbsp;Laís Pereira Silva,&nbsp;Karine Araújo Damasceno,&nbsp;Thanielle Novaes Fontes,&nbsp;Marcos André Nino Rocha,&nbsp;Stella Maria Barrouin-Melo,&nbsp;Marília Carneiro de Araújo Machado,&nbsp;Alessandra Estrela-Lima","doi":"10.1016/j.tcam.2026.101078","DOIUrl":"10.1016/j.tcam.2026.101078","url":null,"abstract":"<div><div>In cats, the high incidence of malignant mammary neoplasms with elevated rates of metastasis and recurrence underscores the need for more effective therapies to prevent disease progression. This preliminary study evaluated the impact of carboplatin or bleomycin electrochemotherapy on recurrence rates, adverse effects, and overall survival in female cats with mammary carcinoma undergoing mastectomy. Thirty-four female cats with mammary carcinoma were assigned to four groups: Group 1 (mastectomy), Group 2 (mastectomy plus chemotherapy), Group 3 (mastectomy plus electrochemotherapy with carboplatin and chemotherapy), and Group 4 (mastectomy plus electrochemotherapy with bleomycin and chemotherapy). The tumors were classified and graded histologically, and the proliferative index was assessed using Ki-67. Most cases were stage III, and 50% had nodal metastases. The predominant tumor types included cribriform carcinoma and histological grade II. All groups showed a high Ki-67 proliferation index (&gt;20%), with no significant differences (p = 0.753). Hematocrit values in the fourth chemotherapy session were higher in G3 than in G2 (p = 0.022). The highest numerical recurrence rate occurred in G1, while no recurrences were observed in G2 or G4 during follow-up; however, this difference did not reach statistical significance (p = 0.086). Overall survival analysis showed a 82% mortality rate; G1 had 100% mortality, with a significant difference compared with the other groups (p = 0.0287). More chemotherapy sessions (≥5) were significantly associated with increased overall survival (p = 0.002), adding a mean of 39.1 days to disease-free survival per additional session. Taken together, these preliminary findings suggest that mastectomy alone was insufficient to control progression the cancer. Carboplatin-based protocols, whether used as conventional chemotherapy or combined with electrochemotherapy, showed lower recurrence rates, fewer adverse effects, and longer overall survival. However, due to the limited sample size, these results should be interpreted with caution. Further studies with larger cohorts are warranted to confirm these observations</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"72 ","pages":"Article 101078"},"PeriodicalIF":1.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148255300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of 24-hour sedation during mechanical ventilation on hematological, biochemical, and coagulation parameters in bitches: A randomized clinical study","authors":"Doughlas Regalin,&nbsp;Barbara Ataíde Adorno,&nbsp;Natielly Dias Chimenes,&nbsp;Diego Ribeiro,&nbsp;Reiner Silveira de Moraes,&nbsp;Luíz Guilherme Dércore Benevenuto,&nbsp;Gilberto Serighelli-Júnior,&nbsp;Mere Erika Saito,&nbsp;Felipe Comassetto,&nbsp;Bruna Ditzel da Costa Regalin,&nbsp;Vanessa Sasso Padilha,&nbsp;Julieta Volpato,&nbsp;Nilson Oleskovicz","doi":"10.1016/j.tcam.2026.101092","DOIUrl":"10.1016/j.tcam.2026.101092","url":null,"abstract":"<div><div>The effects of prolonged sedation on hematological, biochemical, and coagulation variables have not been previously investigated in veterinary medicine. Twelve healthy adult mixed-breed female dogs were included. Blood samples (6 mL) were collected at baseline (M0) for complete blood count (CBC), biochemical testing, prothrombin time (PT), activated partial thromboplastin time (PTT) and fibrinogen. After M0, dogs were allocated into two groups: midazolam-fentanyl-propofol group (MFG; n = 6), which received a continuous infusion of midazolam (0.5 mg/kg/h), fentanyl (10 µg/kg/h), and propofol (18 mg/kg/h); and ketamine-morphine-propofol group (KMG; n = 6), which received a continuous infusion of ketamine (0.6 mg/kg/h), morphine (0.26 mg/kg/h), and propofol (18 mg/kg/h). The infusion was maintained for 24 hours under mechanical ventilation. Laboratory parameters were reassessed from 12 to 24 hours after the beginning of infusion (M12 and M24), and at 12, 24, and 48 hours after the infusion (T12, T24, and T48). Both protocols significantly reduced erythrocyte count, packed cell volume, and haemoglobin concentration. In KMG, TTP decreased significantly at M12, M24, and T24; TSP at M24; and lymphocytes at M12 and M24. No significant changes were observed in ALP, ALT, albumin, globulins, creatinine, urea, glucose and blood coagulation. Triglyceride and cholesterol concentrations increased significantly from M6 to T48, but without biochemical evidence of hepatic, renal, or coagulation impairment. Overall, both protocols induced transient hematological and biochemical changes without clinically meaningful alterations in hepatic or renal function, supporting their use in healthy dogs mechanically ventilated for 24 hours.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"72 ","pages":"Article 101092"},"PeriodicalIF":1.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148671669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Simply adding positive end-expiratory pressure has limited effects on oxygenation in obese dogs","authors":"Manuel Martin-Flores,&nbsp;Joaquin Araos,&nbsp;Taylor A. Rondon","doi":"10.1016/j.tcam.2026.101090","DOIUrl":"10.1016/j.tcam.2026.101090","url":null,"abstract":"<div><div>Positive end-expiratory pressure (PEEP) can be used to prevent atelectasis during anesthesia. We evaluated the effect of PEEP on intra- and postoperative oxygenation on obese dogs admitted for stifle surgery. Dogs received no PEEP (ZEEP; n = 10) or 7 cmH₂O PEEP (n = 9) at random during general anesthesia. The partial pressure of arterial oxygen (PaO₂) and its ratio to inspired fractional oxygen (PaO₂:FiO₂) were measured at start and end of surgery (FiO₂ 1.0), and 20, 120, and 240 minutes after extubation (FiO₂ 0.2). Cases of hypoxemia (PaO₂ &lt; 80 mmHg) were identified. There were no differences between treatment for either variable (P &gt; 0.1 for treatment and P &gt; 0.6 for treatment*time, for both variables). There were three cases of postoperative hypoxemia in the ZEEP treatment (P = 0.21). No significant improvement was achieved when PEEP 7 cmH₂O was applied in isolation. Successful use of PEEP may require additional maneuvers.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"72 ","pages":"Article 101090"},"PeriodicalIF":1.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148671702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-reported knowledge and practices of dog owners regarding canine overweight: a cross-sectional questionnaire survey","authors":"Felipe Gaia de Sousa ,&nbsp;Ana Cristina Ribeiro Mendes ,&nbsp;Eduarda Cristina Pereira Severino ,&nbsp;Fernanda do Carmo Magalhães","doi":"10.1016/j.tcam.2026.101057","DOIUrl":"10.1016/j.tcam.2026.101057","url":null,"abstract":"<div><div>Excess body weight (overweight or obesity) is among the most common nutritional conditions in dogs and is frequently associated with an imbalance between caloric intake and energy expenditure. Its detection and management depend on owners’ recognition and management of their pets’ body condition. This study aimed to assess dog owners’ self-reported knowledge and practices regarding excess body weight and to identify the factors associated with it. An online questionnaire was administered to 122 dog owners between November 2024 and January 2025. Statistical analyses included descriptive statistics, correlation analyses, and ordered regression, with a significance level of 5% (<em>p</em> ≤ 0.05). Excess body weight was observed in 46.7% of the dogs, accompanied by a high frequency of daily snack offerings. Although 100% of owners recognized the health risks associated with excess weight, and 92.6% acknowledged the importance of veterinary supervision for management, some reported practices appeared to be inconsistent with this knowledge, such as ad libitum feeding and poor adherence to professional advice. Significant correlations were observed between body condition score and both the animal’s size and the frequency of snack offerings. Regression analysis showed that owners’ time spent at home, as well as dogs’ age, sex, breed type, and type of food, were associated with body condition score. Despite expressed theoretical knowledge, some potentially suboptimal practices were reported. Ongoing educational efforts and collaborative management strategies involving both owners and professionals are essential and may support improvements in management practices and improve dogs’ health and quality of life.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"71 ","pages":"Article 101057"},"PeriodicalIF":1.3,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147793721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seroprevalence of zoonotic vector-borne pathogens in domestic dogs from rural areas in northern Peru","authors":"Luis A. Julca ,&nbsp;Martha Y. Salas-Fajardo ,&nbsp;Soraya Guevara ,&nbsp;Claudio Muro ,&nbsp;Ana Vargas-Calla ,&nbsp;Luis A. Gomez-Puerta","doi":"10.1016/j.tcam.2026.101056","DOIUrl":"10.1016/j.tcam.2026.101056","url":null,"abstract":"<div><div>This study was performed to determine the seroprevalence of zoonotic vector-borne diseases (ehrlichiosis, anaplasmosis, dirofilariasis, and Lyme disease) in domestic dogs in northern Peru, in rural areas of the Tumbes department. Blood samples were collected from dogs (n = 169) from three districts of the province of Tumbes: Garbanzal (n = 59), Puerto Pizarro (n = 59) and Rica Playa (n = 51). The samples were tested using a commercial enzyme-linked immunosorbent assay to check for <em>Ehrlichia</em> spp., <em>Anaplasma</em> spp., <em>Borrelia burgdorferi</em>, and <em>Dirofilaria immitis</em>. The results showed a seroprevalence of 77.5% (131/169) for <em>Ehrlichia</em> spp., 37.9% (64/169) for <em>Anaplasma</em> spp., and 26% (44/169) for <em>D. immitis</em>. No positive dogs for <em>B. burgdorferi</em> antibodies were detected in this study. A statistically significant association was found between dogs seropositive for <em>Ehrlichia</em> spp. and the variables age (p = 0.002), breeding place (p = 0.003), and breed type (p = 0.032). Furthermore, dogs infected with <em>D. immitis</em> were associated with the age (p = 0.001), locality (p &lt; 0.001), and breeding place (p = 0.001). These findings confirm a high prevalence of zoonotic vector-borne diseases affecting domestic dogs in rural areas of northern Peru.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"71 ","pages":"Article 101056"},"PeriodicalIF":1.3,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147793838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac involvement in European canine babesiosis - a pathological perspective","authors":"Doroteja Huber,&nbsp;Dunja Vlahović,&nbsp;Ivana Mihoković Buhin,&nbsp;Lidija Medven Zagradišnik,&nbsp;Branka Artuković,&nbsp;Marko Hohšteter,&nbsp;Ivan-Conrado Šoštarić-Zuckermann","doi":"10.1016/j.tcam.2026.101060","DOIUrl":"10.1016/j.tcam.2026.101060","url":null,"abstract":"<div><div>Canine babesiosis is an important and potentially life-threatening disease of worldwide significance. European babesiosis encompasses all protozoan parasites of the genus <em>Babesia</em> that have been reported to cause canine disease in Europe. Despite its importance, cardiac pathology associated with European babesiosis remains poorly characterized. The aim of this study was to assess cardiac lesions in dogs that succumbed to European babesiosis.</div><div>For this study, the archive of the Department of Veterinary Pathology, Faculty of Veterinary Medicine Zagreb, was retrospectively searched for necropsied dogs which died as a consequence of naturally acquired European babesiosis. Babesiosis was diagnosed by detection of trophozoites within erythrocytes, but not lymphocytes, in cytological and/or histological slides. Necropsy reports, photographs of cardiac gross lesions, and histologic slides of the heart were reviewed, and all changes were noted.</div><div>The most common gross pathologies were hemorrhage and pericardial effusion, while intravascular monocytic leukostasis, hemorrhage, endomysial edema, myocardial necrosis, congestion, and myocarditis were the most frequent histologic findings. Based on results of the current study, cardiac lesions in clinical cases of complicated European babesiosis should be expected and patients should be evaluated for such damage.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"71 ","pages":"Article 101060"},"PeriodicalIF":1.3,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147848460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retrospective analysis of reproductive tract disease incidence in intact female African pygmy hedgehogs (Atelerix albiventris)","authors":"Lucia Kasalová ,&nbsp;Hana Černochová ,&nbsp;Radka Dvořáková ,&nbsp;Aneta Angelová ,&nbsp;Kristína Řeháková","doi":"10.1016/j.tcam.2026.101061","DOIUrl":"10.1016/j.tcam.2026.101061","url":null,"abstract":"<div><h3>Background</h3><div>Reproductive tract disease is frequently reported in African pygmy hedgehogs, yet the true prevalence and spectrum of lesions remain unclear. Clinical information is often limited to case description, and mild or chronic pathologies may be underdiagnosed.</div></div><div><h3>Objectives</h3><div>To determine the prevalence, types, and clinical characteristics of reproductive tract disease in female African pygmy hedgehogs, and to evaluate the diagnostic value of haematology, plasma biochemistry, vaginal cytology, ultrasonography, histopathology, and microbiological culture.</div></div><div><h3>Methods</h3><div>A retrospective study was performed of 53 female hedgehogs presented between May 2O22 and June 2024. Three previously sterilised animals were excluded. Clinical signs, diagnostic findings, and histopathological results were analysed descriptively.</div></div><div><h3>Results</h3><div>Reproductive tract disease was identified in 32% (16/50) of intact females. The median age of affected animals was 3.5 years. Uterine masses were detected in 56% (9/16) of affected females. Neoplasia was confirmed in 55% (5/9) cases of these presented uterine masses(stromal sarcoma, leiomyosarcoma an including endometrial polyp). Chronic superficial endometritis and cystic endometrial hyperplasia occurred in 50% (8/16)of cases. Bacterial culture was positive in 44% of the obtained samples (4/9), predominantly <em>Escherichia coli, Streptococcus dysgalactiae, Klebsiella oxytoca,</em> and <em>Proteus vulgaris</em>. Common haematological abnormalities included monocytosis and anaemia. Ultrasonography reliably detected uterine enlargement, fluid accumulation, cystic changes, and mass-like lesions. Vaginal cytology provided supportive evidence of inflammation.</div></div><div><h3>Conclusion</h3><div>Reproductive tract disease in female African pygmy hedgehogs presents a broader range of inflammatory and hyperplastic conditions than previously recognised. Ultrasonography, haematology, and vaginal cytology offer valuable diagnostic information, and preventive sterilisation should be considered to reduce the risk of reproductive pathology.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"71 ","pages":"Article 101061"},"PeriodicalIF":1.3,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147871156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}