Topics in companion animal medicine最新文献

{"title":"All pet owners are not the same: End-of-Life caregiver expectations and profiles.","authors":"Sara Hoummady ,&nbsp;Laureline Chaise ,&nbsp;Marion Guillot ,&nbsp;Nancy Rebout","doi":"10.1016/j.tcam.2025.100960","DOIUrl":"10.1016/j.tcam.2025.100960","url":null,"abstract":"<div><div>The study aims to explore the specific needs of French pet owners who have experienced the loss of a pet, recognizing the limited focus on end-of-life and palliative care in veterinary practice. By characterizing owner profiles, the research seeks to enhance veterinary approaches and education to better address the unique challenges and emotional aspects associated with pet care and loss. An anonymous online survey was distributed to 302 French owners who already experienced the loss of an animal, including demographic information and feelings about their experience of a pet's end-of-life (EOL). Data were analysed using descriptive and qualitative analysis (including the use of AI chatbot ChatGPT). 56.6 % of participants reported a relatively smooth pet death, yet 67.0 % found the end-of-life period challenging. Three distinct owner groups emerged, each with varying needs. The first group expressed high guilt and a greater need for support, emphasizing the necessity for information and improved training. The second group, more informed and independent, benefits from veterinary support, while a leaflet suits them. The third group, competent in pain evaluation, requires less veterinary support. These differences highlight the importance of personalized owner support. The study proposes essential pillars for veterinarians and nurses' training, forming the EPITO system: Emotional support, Personalization, Information, Training, Tools, and Open discussion.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"65 ","pages":"Article 100960"},"PeriodicalIF":1.3,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143372718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidural administration of tramadol does not provide sufficient intraoperative analgesia for elective ovariohysterectomy in healthy cats","authors":"Franco IG ,&nbsp;Souza AR ,&nbsp;Costa IM ,&nbsp;Julião GH ,&nbsp;Oliveira BB ,&nbsp;Nishimura HML ,&nbsp;Abimussi CJX ,&nbsp;Floriano BP","doi":"10.1016/j.tcam.2025.100959","DOIUrl":"10.1016/j.tcam.2025.100959","url":null,"abstract":"<div><div>Few studies today address trans-operative analgesia provided by tramadol without local anesthetics for intra-abdominal procedures. The objective of this study was to assess the efficacy of trans-operative analgesia provided by epidurally administered tramadol in cats undergoing elective ovariohysterectomy. For this purpose, 16 healthy queens were randomly assigned to participate in one of two groups: GC, control group, 0.9% NaCl at 0.3 mL/kg; and GT, tramadol group, tramadol 1 mg/kg in saline to the same final volume. Subjects received premedication with ketamine, xylazine and morphine and were anesthetized and maintained with a propofol infusion at 0.4-0.8 mg/kg/min until the end of surgery. Variables heart rate (HR), respiratory rate (F_R) and systolic blood pressure (SAP) were recorded before epidural injection (TB), 5 minutes after epidural injection (TAE), at surgical incision of the skin (TSI), at clamping of the first ovarian pedicle (TP1), at clamping of the second pedicle (TP2), at clamping of the uterine stump (TU), at the beginning of abdominal cavity closure (TC) and at the final suture of the skin (TFS). A bolus of fentanyl 2 μg/kg was administered IV in case of a 20% increase of physiologic variables during these times. At the end of the study, data was analyzed using ANOVA for repeated measures followed by Tukey test. The number of fentanyl boluses was compared between groups using Kruskal-Wallis followed by Dunn test. All analyses were performed under 5% significance. There were no significant differences in HR, F_R and SAP between groups. Only a mild difference was seen in HR in GT at times MP1, MP2, MU and MC compared to baseline (before epidural injections). There were no differences in number of fentanyl boluses between groups, with median (range) of 3 (1–5) in GC and 3 (1–4) in GT. In conclusion, tramadol given epidurally to cats undergoing elective ovariohysterectomy does not provide reliable intraoperative analgesia, and therefore other strategies are necessary to ensure intraoperative analgesia of healthy cats during elective ovariohysterectomy.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"65 ","pages":"Article 100959"},"PeriodicalIF":1.3,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143070480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of selected nutrients and contaminants in fish oil supplements for dogs*","authors":"Lauren R. Ober ,&nbsp;Jennifer A. Larsen ,&nbsp;Lauren E. Hoffman ,&nbsp;Birgit Puschner ,&nbsp;Andrea J. Fascetti","doi":"10.1016/j.tcam.2025.100949","DOIUrl":"10.1016/j.tcam.2025.100949","url":null,"abstract":"<div><div>Fish oil supplements for dogs are used therapeutically for various clinical conditions. However, products may be variable in quality, potency, and stability. The objective of this study was to analyze eleven canine fish oil supplements from two time points (2010 and 2021) for the omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), polychlorinated biphenyl (PCB) arochlors, minerals, and vitamins A and D, and to compare their compositions to label claims. Molybdenum, cadmium, mercury, lead, and PCBs were not detected in any samples. Other minerals were detected in some products, and concentrations were well below general maximum tolerable levels or applicable regulatory maximums for dog foods. EPA and DHA concentrations varied widely among products and between timepoints. Overall, there were six instances of products not meeting label claims within 5 % for EPA, DHA, or both. Across both timepoints, five minimum content claims were made for vitamin A, and three for vitamin D. In 2010, the analyzed concentrations were below the claims for one product each for vitamins A and D, while for 2021 all products met their respective claims. Overall, products were assessed to have low risk for vitamins A and D or mineral toxicoses when used as recommended. At higher (therapeutic) doses, contributions to the overall intake for nutrients of concern should be considered, including selenium and fat soluble vitamins. In addition, there is room for improvement for manufacturers to ensure accurate label guarantees.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"65 ","pages":"Article 100949"},"PeriodicalIF":1.3,"publicationDate":"2025-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142960921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring risk factors linked to canine lymphoma: a case-control study","authors":"Katia Pinello ,&nbsp;Liliana Leite-Martins ,&nbsp;Hugo Gregório ,&nbsp;Filipe Oliveira ,&nbsp;Katia C. Kimura ,&nbsp;Maria Lúcia Z. Dagli ,&nbsp;Augusto de Matos ,&nbsp;João Niza-Ribeiro","doi":"10.1016/j.tcam.2025.100948","DOIUrl":"10.1016/j.tcam.2025.100948","url":null,"abstract":"<div><div>Environmental factors, largely influenced by human behavior, account for approximately 80 % of malignant tumors. Risk factors associated with non-Hodgkin's lymphoma (NHL) have been identified in various countries among both humans and domestic animals. This study aimed to investigate potential risk factors for NHL in dogs residing in the district of Porto, Portugal. A comprehensive survey comprising 70 questions was undertaken and given to 113 dog owners, including 55 cases and 58 controls. Our findings revealed that dogs weighing over 10 kg (OR=9.1, <em>p</em> &lt; 0.001), purebred dogs (OR=2.4, <em>p</em> = 0.037), those with consuming homemade food (OR=2.7, <em>p</em> = 0.03), and fruits and vegetables (OR=2.8, <em>p</em> = 0.022) exhibited higher odds of developing lymphoma. Notably, dogs with lymphoma were exposed to a significantly higher mean smoking index compared to the control group (13.7, SD=12.5 vs. 8.4, SD=9.3, <em>p</em> &lt; 0.001). These findings suggest that lymphoma risk in dogs seems to be influenced by a combination of innate (genetic) factors and modifiable environmental factors linked to owner habits. Nevertheless, further large-scale epidemiological studies are warranted to validate these results.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"65 ","pages":"Article 100948"},"PeriodicalIF":1.3,"publicationDate":"2025-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142934179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of a constant rate infusion of ketamine on left ventricular systolic and diastolic function in dogs anesthetized with propofol","authors":"Guilherme Andraus Bispo ,&nbsp;Thaís Cabral de Oliveira ,&nbsp;Matheus Fujimura Soares ,&nbsp;Izabella Pazzoto Alves ,&nbsp;Élen Almeida Pedreira de Souza ,&nbsp;Carlos Eduardo de Siqueira ,&nbsp;Marilda Onghero Taffarel ,&nbsp;Wagner Luis Ferreira ,&nbsp;Paulo Sergio Patto dos Santos","doi":"10.1016/j.tcam.2024.100931","DOIUrl":"10.1016/j.tcam.2024.100931","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the effect of a constant rate infusion of ketamine on left ventricular systolic and diastolic function in dogs anesthetized with propofol.</div></div><div><h3>Study design</h3><div>Prospective randomized, blinded clinical study.</div></div><div><h3>Animals</h3><div>Sixteen healthy dogs.</div></div><div><h3>Methods</h3><div>Dogs were randomized into two groups, the propofol-ketamine group (GPK) and propofol group (GP), with eight animals each. Anesthesia was induced with propofol and maintained with a constant rate infusion (CRI) of propofol at a rate of 0.8 mg/kg/min. All dogs were mechanically ventilated throughout the study. Thirty-five minutes after anesthesia started, the GPK received a bolus of ketamine (0.5 mg/kg IV, over 2 minutes) followed by the CRI of ketamine at 30 μg/kg/min, while the GP received the same volume of 0.9% NaCl over 2 minutes followed by the CRI of 0.9% NaCl at the same rate. Hemodynamic and echocardiographic variables were recorded 15 min after initiating CRI of propofol (M0), immediately after each treatment bolus (M1), and 20 (M2) and 40 min (M3) after initiating CRI of ketamine or 0.9% NaCl solution in both groups.</div></div><div><h3>Results</h3><div>Cardiac index, stroke index, and peripheral vascular resistance index were not significantly different between treatments. No significant differences in left ventricular systolic and diastolic functions derived from echocardiographic variables were observed between groups.</div></div><div><h3>Conclusions and clinical relevance</h3><div>During treatment with CRI of ketamine at the proposed rate, hemodynamic parameters and echocardiographic variables, used to measure left ventricular systolic and diastolic function, were maintained stable in healthy dogs anesthetized with propofol.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"64 ","pages":"Article 100931"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142776162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is anti-müllerian hormone useful for monorchidism diagnosis in the tomcat?","authors":"Florin Petrișor Posastiuc ,&nbsp;Nicolae Tiberiu Constantin ,&nbsp;Cătălin Micșa ,&nbsp;George Nicolae ,&nbsp;Alexandru Ilie Diaconescu ,&nbsp;Mario Darius Codreanu ,&nbsp;Andreea Iren Șerban ,&nbsp;Ann Van Soom","doi":"10.1016/j.tcam.2024.100947","DOIUrl":"10.1016/j.tcam.2024.100947","url":null,"abstract":"<div><div>Monorchidism is an uncommon condition in tomcats, defined by the congenital absence of one of the testicles. Due to the lack of information regarding possible biomarkers, most monorchidism cases require laparotomy in order to differentiate it from cryptorchidism. Human data suggest that monorchid patients have lower serum anti-Müllerian hormone (AMH) levels when compared to cryptorchids, premises that has been also scrutinized in veterinary medicine. Here, we describe a case of monorchidism in a tomcat, focusing on the clinical findings and the dynamics of AMH serum levels before and after the removal of the singularly identified testicle. To contribute to the limited knowledge of AMH levels across different reproductive statuses in tomcats, the findings from this monorchid case were compared to values obtained from two cryptorchid tomcats (one unilateral and one bilateral), three intact tomcats, and three castrated tomcats. In addition, clinical, histopathological and ultrasound examinations were conducted in all tomcats. The AMH levels in the monorchid tomcat revealed a consistent decrease after surgery, from 27.3 ± 0.2 ng/ml when the testicle was still present, to 2.3 ± 0.2 ng/ml 1 week later, and further decreasing below the detection limit (&lt;0.15 ng/ml) for the last 2 weeks of the trial, matching the AMH level of the castrated male. AMH serum levels of the bilateral and unilateral cryptorchid tomcat (22.5 ± 0.3 ng/ml; 24.1 ± 0.2 ng/ml) were in agreement with those of the three intact males (19.1 ± 2.2 ng/ml) and the monorchid prior to surgery. AMH testing effectively confirmed the absence of testicular tissue after unilateral orchiectomy in a monorchid tomcat but did not differentiate between monorchidism and cryptorchidism. To our knowledge, this is the first case of monorchidism in tomcats, in which AMH levels before and after surgery have been determined.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"64 ","pages":"Article 100947"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142901509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trazodone-gabapentin association increases sedation scores with mild hemodynamic and echocardiographic impact in healthy cats","authors":"Ellen Cristina Siepmann,&nbsp;Estela Dall’ Agnol Gianezini,&nbsp;Maria Eduarda Ruaro,&nbsp;Luciana Wolfran,&nbsp;Caique Aparecido Faria,&nbsp;Fabiola Bono Fukushima","doi":"10.1016/j.tcam.2024.100945","DOIUrl":"10.1016/j.tcam.2024.100945","url":null,"abstract":"<div><div>Despite the increasing use of drugs to facilitate feline management in veterinary care, there is still a lack of information on the anxiolytic and sedative effects and their specific physiological impacts. We aimed to compare the sedative, hematological, biochemical and cardiovascular effects of oral single-dose trazodone and gabapentin, alone or in combination, in 8 healthy adult mixed-breed domestic cats on a prospective, randomized, cross-over, and placebo-controlled study. Cats were assigned to receive an oral single dose of trazodone (50 mg) (TG), gabapentin (100 mg) (GG), trazodone (50 mg) and gabapentin (100 mg) (GTG), or placebo (PG). Sedation score, physiological, hematological, biochemical, and cardiovascular variables were assessed at baseline and 120 minutes after drug administration. The mean dose of trazodone was 12.1± 1.1 mg/kg and gabapentin 24.2± 2.3 mg/kg. All data were normally distributed. Blood tests remained within the reference range, but plasma protein increased by 3.78 % in TG. Trazodone alone and associated with gabapentin significantly reduced respiratory rate and systolic blood pressure compared to baseline and placebo. GTG showed a reduction in heart rate and the highest sedation scores. Short-duration excitatory reactions were observed in 37.5 % of the cats in GTG and 12.5 % in TG. Isovolumetric relaxation time (IVRT) increased in GTG and differed statistically from GG. On ECG, no clinically relevant changes were observed. The association of trazodone (50 mg/cat) and gabapentin (100 mg/cat) increases sedation scores compared to gabapentin alone, with a mild impact on HR, RR, BP, and IVRT in cats.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"64 ","pages":"Article 100945"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142866949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of diagnostic accuracy and inter-pathologist agreement in telecytology performed for canine round cell tumours using images captured by a smartphone camera","authors":"Lakshitha Piyum ,&nbsp;Thamali Manathunga ,&nbsp;Yashoda Wickramasinghe ,&nbsp;Nishadi Bandaranayaka ,&nbsp;Kavindhya Senarathne ,&nbsp;Vidura Gajanayaka ,&nbsp;Harsha Ariyarathna","doi":"10.1016/j.tcam.2024.100946","DOIUrl":"10.1016/j.tcam.2024.100946","url":null,"abstract":"<div><div>Neoplasia is a common disease in companion animals. Rapid and accurate diagnosis of neoplasia often leads to a better disease outcome. Cytology is an inexpensive and minimally invasive method frequently used to diagnose neoplasia. However, the physical distance between veterinary practices and pathologists often impedes rapid diagnosis. Telecytology facilitates rapid interpretation of cytology results leading to prompt diagnosis. Smartphone cameras have been suggested as an alternative to image-capturing devices used in conventional telecytology. This project was designed to evaluate whether telecytology with smartphone cameras can be effectively used to diagnose canine round cell neoplasms. For this purpose, five round cell tumours [lymphoma, mast cell tumour (MCT), transmissible venereal tumour (TVT), plasmacytoma and histiocytoma] were imaged using a smartphone camera and the images were sent to two pathologists at distant locations via emails. For each tumour type, the cytopathological diagnosis from the two pathologists was compared with the histopathological diagnosis of the same tumour and the agreement was determined by Cohen's kappa test. Inter-pathologist variability was also determined using the same test. The diagnostic agreement between histopathology and cytopathology was excellent (κ = 1.0) for lymphoma and MCT when x10 objective images were used. Variable agreements were reported for TVT, plasmacytoma and histiocytoma. When both 10x and 40x objective images were used, diagnostic agreement between histopathology and cytopathology was excellent for all tumours except histiocytoma. The inter-pathologist agreement was excellent for lymphoma, MCT and TVT using the 10x objective, while with the 40x objective it was excellent for all tumours except histiocytoma. The diagnostic accuracy was greater when both 10x and 40x objective images were used for diagnosis than when only 10x objective images were used (χ2 = 40.0, p = &lt; 0.001). The use of images obtained using 10x and 40x objectives increased the diagnostic accuracy compared to the use of only 10x objective. These findings suggest that telecytology performed with smartphone cameras is a promising method to rapidly diagnose canine round cell tumours. Future studies with larger number of samples and samples with atypical presentations of round cell neoplasms will be helpful to further elaborate the present findings.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"64 ","pages":"Article 100946"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142866947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Proximal tibial osteotomies for treating grade IV medial patellar luxation in two feline stifles","authors":"Gabriela Mariano da Silva ,&nbsp;Alefe Luiz Caliani Carrera ,&nbsp;Olicies da Cunha ,&nbsp;Bruno Watanabe Minto ,&nbsp;Eloy Henrique Pares Curuci","doi":"10.1016/j.tcam.2024.100944","DOIUrl":"10.1016/j.tcam.2024.100944","url":null,"abstract":"<div><h3>Objectives</h3><div>There is a lack of literature regarding the surgical management of high-grade patellar luxation in cats. Among the available options, corrective osteotomies are suitable for correcting severe bone deformities. Therefore, this study aimed to report on the surgical management of grade IV medial patellar luxation (MPL) through tibial corrective osteotomies in two cats.</div></div><div><h3>Material and Methods</h3><div>The two cats were diagnosed with grade IV MPL. The marked alterations observed in radiographic and tomographic images indicated external tibial torsion of 15.7° and 21.8°, concomitant with tibial valgus of 13.9° and a tibial plateau angle (TPA) of 20°, respectively. For surgical treatment, chrondoplasty was performed in Case 1, and block recession trochleoplasty in Case 2, followed by a combination of techniques originally developed for dogs. Proximal total tibial osteotomy (PTO) was combined with medial crescentic closing wedge osteotomy (MCCWO) for one case and with cranial closing wedge ostectomy (CCWO) for the other case.</div></div><div><h3>Results</h3><div>Satisfactory postoperative results were obtained for both cats, resulting in realignment of the stifle extensor mechanism, with both tibial torsions close to 0° in subjective analysis. Additionally, a mechanical medial proximal tibial angle of 91° and a mechanical medial distal tibial angle of 99.3° were achieved for the first cat, whereas a TPA of 9.2° was achieved for the second cat. No major complications were observed, and the cats showed an early return to weight-bearing on the affected limb.</div></div><div><h3>Conclusion</h3><div>Both cases highlight that tibial corrective osteotomies are suitable for cats and may play a role in the decision-making process for treating high-grade MPL. Moreover, a combination of PTO with MCCWO or CCWO may help achieve satisfactory outcomes.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"64 ","pages":"Article 100944"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142866948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of postoperative hyperbaric oxygen therapy on hematological and biochemical parameters in patients diagnoses with pyometra in sepsis","authors":"Emanuelle Bortolotto Degregori ,&nbsp;Pâmela Caye ,&nbsp;Ana Barbara Uchoa Soares ,&nbsp;Otávio Henrique de Melo Schiefler ,&nbsp;Bernardo Nascimento Antunes ,&nbsp;Rainer Da Silva Reinstein ,&nbsp;Francieli Mallmann Pozzobon ,&nbsp;Vitória Pina Tostes ,&nbsp;Rainier Augusto Rovêda ,&nbsp;Vinicius da Silva Cadiñanos ,&nbsp;Cinthia Melazzo de Andrade ,&nbsp;Maurício Veloso Brun ,&nbsp;Daniel Curvello de Mendonça Müller","doi":"10.1016/j.tcam.2024.100943","DOIUrl":"10.1016/j.tcam.2024.100943","url":null,"abstract":"<div><div>The aim of this study was to evaluate the impact of hyperbaric oxygen therapy (HBOT) on hematologic and biochemical markers in dogs with pyometra in sepsis. Eighteen patients were equally distributed between the control group (CG) and the hyperbaric group (HG). All patients underwent ovariohysterectomy, supportive therapy, and insertion of a central venous catheter. HG attended three HBOT sessions (2 absolute atmospheres, 45 min) postoperatively. Blood tests were performed on admission, 1 h postoperatively, 24 h, 48 ​​h, and 72 h postoperatively. Both groups showed a significant reduction in red blood cells (Hm) and hematocrit (Hto) after surgery, but this effect was reversed after three HBO sessions and maintained in CG. Despite the initial reduction in hemoglobin (Hg) in HG, the values ​​increased again after the end of the protocol. A reduction of &gt;50 % in leukocytes was noted in HG in the last evaluation in relation to the values ​​at admission. Significant reduction was also found for neutrophils, metamyelocytes and rods in HG. There was no difference in biochemical markers. HBO associated with OVH and supportive therapy can be considered in the treatment of pyometra, with rapid and marked improvement, after three sessions, in the e red blood cells and leukogram.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"64 ","pages":"Article 100943"},"PeriodicalIF":1.3,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142831434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}