Topics in companion animal medicine最新文献

Coinfection of Klebsiella oxytoca and Granulicatella adiacens promoting fatal fibrinonecrotic enteritis in a red footed-tortoise (Chelonoidis carbonaria) 在红脚龟（Chelonoidis carbonaria）中，氧化克雷伯氏菌和粘连肉芽菌的共同感染促进致死性纤维蛋白坏死性肠炎。

IF 1.3 3区农林科学

Topics in companion animal medicine Pub Date : 2025-07-01 DOI: 10.1016/j.tcam.2025.100995

Tainara Soares Weyh , Gabriela Merker Breyer , Carolina Buss Brunner , Flávia Ferrari , Luciana Sonne , Franciele Maboni Siqueira

{"title":"Coinfection of Klebsiella oxytoca and Granulicatella adiacens promoting fatal fibrinonecrotic enteritis in a red footed-tortoise (Chelonoidis carbonaria)","authors":"Tainara Soares Weyh , Gabriela Merker Breyer , Carolina Buss Brunner , Flávia Ferrari , Luciana Sonne , Franciele Maboni Siqueira","doi":"10.1016/j.tcam.2025.100995","DOIUrl":"10.1016/j.tcam.2025.100995","url":null,"abstract":"<div><div>Enteric bacterial infections in reptiles are commonly caused by Gram-negative bacteria with zoonotic importance, with few reports of Gram-positive bacteria as a causative agent of such infections. This case report presents a fatal case of fibrinonecrotic enteritis in a red-footed tortoise. After necropsy, microscopic and microbiological analyses of the small intestine were performed, suggesting the occurrence of a coinfection with two bacteria. Both isolates were subjected to partial 16S-rDNA sequencing and identified as <em>Klebsiella oxytoca</em> and <em>Granulicatella adiacens</em>. While <em>Klebsiella oxytoca</em> is a well-documented pathogen in reptiles, <em>Granulicatella adiacens</em> has previously been reported only in abscesses of domestic rabbits (<em>Oryctolagus cuniculus</em>), injured tissues of Ozark hellbenders (<em>Cryptobranchus alleganiensis bishopi</em>), and human infections, suggesting a potential unexplored zoonotic risk. This is the first report of enteric co-infection with <em>K. oxytoca</em> and <em>G. adiacens</em>, highlighting the need for further investigation into the potential impact of <em>G. adiacens</em> on reptile health and its possible zoonotic implications.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"67 ","pages":"Article 100995"},"PeriodicalIF":1.3,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144602712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analgesic efficacy of pregabalin in dogs undergoing mastectomy with ovariohysterectomy 普瑞巴林在犬乳腺切除合并卵巢子宫切除术中的镇痛效果

IF 1.3 3区农林科学

Topics in companion animal medicine Pub Date : 2025-06-23 DOI: 10.1016/j.tcam.2025.100993

Letícia M.L. Cerazo , Luiza G. Peruchi , Tatiane S. Bruno , Camila Z. Segatto , Gabriel M. Nicácio , Renata N. Cassu

{"title":"Analgesic efficacy of pregabalin in dogs undergoing mastectomy with ovariohysterectomy","authors":"Letícia M.L. Cerazo , Luiza G. Peruchi , Tatiane S. Bruno , Camila Z. Segatto , Gabriel M. Nicácio , Renata N. Cassu","doi":"10.1016/j.tcam.2025.100993","DOIUrl":"10.1016/j.tcam.2025.100993","url":null,"abstract":"<div><div>The aim of this study was to evaluate the analgesic efficacy of pregabalin in dogs diagnosed with mammary carcinoma undergoing mastectomy with ovariohysterectomy. In a randomized, blinded, clinical, placebo-controlled study, 24 dogs were assigned to receive either an oral pregabalin suspension (4 mg/kg/0.1 mL/kg, Pregabalin group, n = 12) or a placebo solution (0.1 mL/kg, Placebo group, n = 12), administered 60 minutes before and every 8 hours after surgery. The dogs were premedicated with intramuscular (IM) morphine (0.3 mg/kg). Anesthesia was induced with intravenous (IV) propofol at a sufficient dose to allow intubation and was maintained with isoflurane. Intraoperatively, a constant rate infusion of morphine (0.1 mg/kg/h) was maintained until the end of surgery. Meloxicam (0.2 mg/kg, IV) was administered immediately after intubation. Intraoperatively, fentanyl (2.5 µg/kg, IV) was administered to control cardiovascular responses to surgical stimulation. Pain was assessed using the short-form Glasgow Composite Pain Scale 24 hours prior to surgery (baseline) and at 0.5, 1, 2, 4, 6, 8, 12, and 24 hours after extubation. Sedation scores were evaluated at the same time points using a descriptive numerical scale. Morphine (0.5 mg/kg, IM) was administered as rescue analgesia. Data were analyzed using t-tests, Fisher's exact test, Kaplan-Meier curve, Mann-Whitney test, and Friedman test. Differences were considered significant when P < 0.05. Pain scores, sedation scores, and analgesic requirements did not differ significantly between groups. Intraoperative fentanyl and postoperative rescue analgesia were required in 100% and 75% of the dogs, respectively, in both treatment groups. In conclusion, as part of a multimodal analgesic protocol, oral pregabalin at 4 mg/kg every 8 hours did not provide additional postoperative analgesic benefits over placebo in dogs undergoing mastectomy with ovariohysterectomy.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"67 ","pages":"Article 100993"},"PeriodicalIF":1.3,"publicationDate":"2025-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144489921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of single-dose intravenous furosemide on basal tear secretion in healthy dogs 单次静脉注射速尿对健康犬基底泪液分泌的影响。

IF 1.3 3区农林科学

Topics in companion animal medicine Pub Date : 2025-06-19 DOI: 10.1016/j.tcam.2025.100994

Keisuke Sugimoto , Miki Yasuike , Akira Matsuda , Yohei Mochizuki , Kiyotaka Arai , Takamasa Itoi , Kenji Kutara , Noritaka Maeta , Yoshiki Itoh

{"title":"Effect of single-dose intravenous furosemide on basal tear secretion in healthy dogs","authors":"Keisuke Sugimoto , Miki Yasuike , Akira Matsuda , Yohei Mochizuki , Kiyotaka Arai , Takamasa Itoi , Kenji Kutara , Noritaka Maeta , Yoshiki Itoh","doi":"10.1016/j.tcam.2025.100994","DOIUrl":"10.1016/j.tcam.2025.100994","url":null,"abstract":"<div><div>This study investigated the effect of intravenous furosemide on basal tear secretion in healthy dogs. Six healthy beagle dogs (three males and three females) aged 1.5–2.8 years were enrolled in this randomized, cross-over, blinded study. All dogs were administered one of three medication protocols in a randomized, cross-over manner: high-dose (HD) furosemide (furosemide 4 mg/kg IV), low-dose (LD) furosemide (furosemide 2 mg/kg IV), or placebo (saline 0.3 mL/kg IV). The Schirmer Tear Test II for dogs was performed to measure basal tear secretion before and 30, 60, 90, and 120 min after the administration of furosemide or saline. Blood samples were collected for total protein (TP) and packed cell volume (PCV) measurements before and 120 min after medication or placebo administration. Basal tear secretion significantly increased in the LD and HD groups compared with that in the placebo group. Significant differences were identified in TP and PCV between the HD and LD, between the HD and placebo groups, and between the LD and placebo groups. In healthy dogs, a significant increase in basal tear secretion was observed in the LD and HD groups compared with that in the placebo group.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"67 ","pages":"Article 100994"},"PeriodicalIF":1.3,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144340731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pet aftercare ordering models: Evolving to meet the needs of today’s pet owner 宠物护理订购模式：不断发展以满足当今宠物主人的需求

IF 1.3 3区农林科学

Topics in companion animal medicine Pub Date : 2025-06-17 DOI: 10.1016/j.tcam.2025.100991

Kathleen Cooney , Lori Kogan

{"title":"Pet aftercare ordering models: Evolving to meet the needs of today’s pet owner","authors":"Kathleen Cooney , Lori Kogan","doi":"10.1016/j.tcam.2025.100991","DOIUrl":"10.1016/j.tcam.2025.100991","url":null,"abstract":"<div><div>Deceased pet aftercare is an important part of a pet owner’s experience and must be handled professionally with great attention to detail by veterinary teams and pet aftercare companies. To facilitate proper body handling, some pet aftercare companies have formed business relationships with veterinary hospitals/clinics, known as a Veterinary Aftercare Ordering Model (VAOM). An alternative model to the VAOM is the Client Aftercare Ordering Model (CAOM), whereby pet owners interact directly with an aftercare company. The goal of this study was to gain insights into veterinary professionals’ experiences and opinions regarding their aftercare model (VAOM or CAOM). An anonymous online survey was distributed through veterinary-related organizations, listservs, and social media sites from March 2024 through July 2024. A total of 772 participants completed the survey, with 21 % of participants reporting currently using a CAOM to support their client’s aftercare ordering needs. The factor reported as most important when using a CAOM was the ability to reduce potential mistakes (e.g., misspelling pet and owner names, contact information, and forgetting memorial item requests). Staff-related factors, including the impact on time needed to review aftercare options with clients, the need to be a liaison between the client and crematory, and the negative perception of appearing to upsell aftercare services, were all rated as more important by veterinary technicians compared to veterinarians. In conclusion, participants found that the use of CAOMs to be positively perceived by their clients and the majority indicated they plan to continue using the model.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"67 ","pages":"Article 100991"},"PeriodicalIF":1.3,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144329981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Partial laryngectomy in a cat with thyroid cartilage osteochondroma: Surgical management and postoperative care 猫甲状腺软骨骨软骨瘤的部分喉切除术：手术处理和术后护理

IF 1.3 3区农林科学

Topics in companion animal medicine Pub Date : 2025-06-17 DOI: 10.1016/j.tcam.2025.100992

Paloma Helena Sanches da Silva, Luíza Bortolotti de Carvalho, Pedro Antônio Bronhara Pimentel, Isabella Oliveira Almeida, Bruna Voltolin de Sena, Paula Baêta da Silva Rios Turquete, Tatiana Geraissate Gorenstein, Eutálio Luiz Mariani Pimenta, Bruno Ferrante, Patrícia Maria Coletto Freitas, Rodrigo dos Santos Horta

引用次数: 0

Mammary neoplasms in male dogs: A 24-year descriptive study 雄性犬乳腺肿瘤：一项为期24年的描述性研究。

IF 1.3 3区农林科学

Topics in companion animal medicine Pub Date : 2025-05-13 DOI: 10.1016/j.tcam.2025.100980

Fernanda Freitas Miranda , Lize Amanda Basaglia Borges , Karen Yumi Ribeiro Nakagaki , Camila Costa Abreu , Geovanni Dantas Cassali

{"title":"Mammary neoplasms in male dogs: A 24-year descriptive study","authors":"Fernanda Freitas Miranda , Lize Amanda Basaglia Borges , Karen Yumi Ribeiro Nakagaki , Camila Costa Abreu , Geovanni Dantas Cassali","doi":"10.1016/j.tcam.2025.100980","DOIUrl":"10.1016/j.tcam.2025.100980","url":null,"abstract":"<div><div>Mammary neoplasms in male dogs are as rare as in humans, accounting for <1% of all tumors. In a descriptive review of cases diagnosed between 2000 and June 2024, 2,172 mammary neoplasms were identified, of which only four (0.18%) occurred in male dogs. The patients ranged in age from 8 to 11 years, with a mean age of 9.7 years. Histopathological analysis revealed that 75% (3/4) of the cases were malignant, while 25% (1/4) were benign. Among the malignant cases, only one patient exhibited regional metastases. Two patients had concurrent testicular neoplasia, both diagnosed as Leydig cell tumors. Malignant histological subtypes included carcinosarcoma, tubular carcinoma, and carcinoma within a mixed tumor. The only benign tumor identified was a benign mixed tumor. All malignant neoplasms exhibited high expression of hormone receptors, highlighting their potential role in tumor development. Additionally, cyclooxygenase-2 (COX-2) expression, a potential therapeutic target and prognostic factor, was observed. Early diagnosis is crucial for improving prognosis; however, due to the rarity of this condition, diagnosis is often delayed. These findings emphasize the occurrence of these neoplasms in male dogs, and report on complementary techniques to improve therapeutic strategies.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"67 ","pages":"Article 100980"},"PeriodicalIF":1.3,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144083112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nosocomial transmission of Sporothrix brasiliensis in two cats 巴西孢子丝菌在两只猫中的医院传播

IF 1.3 3区农林科学

Topics in companion animal medicine Pub Date : 2025-05-01 DOI: 10.1016/j.tcam.2025.100979

Rafael Gariglio Clark Xavier, Salene Angelini Colombo, Brendhal Almeida Silva, Jéssica Rabelo de Oliveira Persichini, Gabriele Silva Duarte, João Victor Ferreira Campos, Rodrigo Otávio Silveira Silva, Maria Isabel de Azevedo

{"title":"Nosocomial transmission of Sporothrix brasiliensis in two cats","authors":"Rafael Gariglio Clark Xavier, Salene Angelini Colombo, Brendhal Almeida Silva, Jéssica Rabelo de Oliveira Persichini, Gabriele Silva Duarte, João Victor Ferreira Campos, Rodrigo Otávio Silveira Silva, Maria Isabel de Azevedo","doi":"10.1016/j.tcam.2025.100979","DOIUrl":"10.1016/j.tcam.2025.100979","url":null,"abstract":"<div><div>Sporotrichosis is a neglected zoonotic infection caused by pathogenic <em>Sporothrix</em> species, primarily affecting the skin and lymphatic system but occasionally leading to life-threatening systemic disease in some cases. Brazil bears the highest global burden of cat and human sporotrichosis. Transmission mainly occurs through traumatic inoculation of the fungus via cat bites, scratches, thorns, or wooden splinters. To date, nosocomial transmission of <em>Sporothrix spp.</em> has not been reported. This report describes two cases of healthcare-associated sporotrichosis in cats in Belo Horizonte (Minas Gerais, Brazil). Both animals (cases 1 and 2) underwent trichotomy at two different veterinary clinics, with both undergoing abdominal ultrasound examination and one (case 2) receiving further venous access. Small skin lesions caused by the trichotomy presented with purulent content approximately six days after the procedure. Samples from the cutaneous lesions were collected and subjected to cytological examination and mycological culture. <em>S. brasiliensis</em> was confirmed through species-specific PCR and calmodulin (<em>CAL</em>) gene sequencing. Phylogenetic analysis revealed that both isolates clustered with clinical <em>S. brasiliensis</em> isolates extracted from infected cats, dogs, and humans in Brazil. These findings highlight the potential for <em>S. brasiliensis</em> transmission through contaminated fur clippers in veterinary hospitals, underscoring the risk of nosocomial infection in animals.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"66 ","pages":"Article 100979"},"PeriodicalIF":1.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143946901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metagenomic and 16S rRNA analysis of culture-negative uterine samples identifies Brucella spp. in a female dog with pyometra

IF 1.3 3区农林科学

Topics in companion animal medicine Pub Date : 2025-05-01 DOI: 10.1016/j.tcam.2025.100981

Rafael Gariglio Clark Xavier , Clarissa Helena Santana , Yasmin Gonçalves de Castro , Rodrigo Dias de Oliveira Carvalho , Tales Fernando da Silva , Vasco Azevedo , Flávia Figueira Aburjaile , Elaine Maria Seles Dorneles , Renato Lima Santos , Rodrigo Otávio Silveira Silva

{"title":"Metagenomic and 16S rRNA analysis of culture-negative uterine samples identifies Brucella spp. in a female dog with pyometra","authors":"Rafael Gariglio Clark Xavier , Clarissa Helena Santana , Yasmin Gonçalves de Castro , Rodrigo Dias de Oliveira Carvalho , Tales Fernando da Silva , Vasco Azevedo , Flávia Figueira Aburjaile , Elaine Maria Seles Dorneles , Renato Lima Santos , Rodrigo Otávio Silveira Silva","doi":"10.1016/j.tcam.2025.100981","DOIUrl":"10.1016/j.tcam.2025.100981","url":null,"abstract":"<div><div>Canine pyometra is the most prevalent reproductive disease in female dogs and involves a complex interplay of hormonal and microbial factors. Although <em>Enterobacteriaceae</em> are known to be the main cause of pyometra, up to 25 % of samples remain negative when classic culture methods are used. The lack of growth in conventional media raises the intriguing possibility that non-cultivable microorganisms participate in the disease. Our study aimed to address this knowledge gap by investigating the microbiota in culture-negative uterine samples from dogs with pyometra. The purulent uterine contents of dogs with pyometra (<em>n</em> = 79) were subjected to bacterial culture. Most of the samples showed bacterial growth of <em>Escherichia coli</em> (48/79, 60.7 %) or other bacterial species (25/79, 31.8 %). Samples that tested negative using the classic culture method (6/79=7.5 %) were further analyzed using 16S rRNA gene sequencing, high-throughput 16S rRNA sequencing, and shotgun metagenomics. Only three of these provided DNA of sufficient quality for further analysis, which revealed a mixture of <em>Haemophilus</em>/<em>Aggregatibacter</em> and <em>Fusobacterium</em>/<em>Porphyromonas</em> in two uterine content. In the third sample, <em>Brucella</em> spp. was identified as the main genus. This study suggests that pathogens that are not easily isolated by classical culture methods, including zoonotic species, may be present in the uterus of dogs with pyometra.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"66 ","pages":"Article 100981"},"PeriodicalIF":1.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143942998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surgical stabilization of a mandibular fracture in a pet African goose (Anser anser domesticus) with bilateral mandibular fractures 宠物非洲鹅（Anser Anser domesticus）双侧下颌骨骨折手术稳定。

IF 1.3 3区农林科学

Topics in companion animal medicine Pub Date : 2025-04-03 DOI: 10.1016/j.tcam.2025.100978

Seunga Min , Miranda J. Sadar , Taylr Wells , Amanda Day , Naomi Hoyer

{"title":"Surgical stabilization of a mandibular fracture in a pet African goose (Anser anser domesticus) with bilateral mandibular fractures","authors":"Seunga Min , Miranda J. Sadar , Taylr Wells , Amanda Day , Naomi Hoyer","doi":"10.1016/j.tcam.2025.100978","DOIUrl":"10.1016/j.tcam.2025.100978","url":null,"abstract":"<div><div>A 7-month-old, 3.8 kg, female intact African goose (<em>Anser anser domesticus</em>), was presented on emergency after being struck by a metal chair during a strong gust of wind. Physical examination revealed ventral displacement of rostral portion of the mandible. A cone beam computed tomography (CBCT) scan confirmed complete, comminuted, bilateral fractures on the rostral portion of the mandibular body. Surgical intervention involved applying external fixation using self-threading Thread Mate System (TMS) pins, orthodontic chains, and dental acrylics to stabilize the right mandible. Indirect reduction and inherent stability were achieved on the left side. An esophagostomy tube was placed to prevent manipulation of the bill during feeding and medication administration in the post operative period. The goose prematurely removed the esophagostomy tube and dental acrylics 10 days after surgery. At the two week post-operative recheck, the bill was stable on palpation and the goose was using it for eating and drinking without complications. At follow-up examination one month after surgery, the goose continued to clinically do well, but all fixations had been self-removed. A repeat CBCT scan revealed bony callus formation of the left fracture site and fibrous callus with incomplete osseous bridging of the right fracture site consistent with delayed union. At 8 months post-operatively, the goose was clinically normal without functional impairment to the bill.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"66 ","pages":"Article 100978"},"PeriodicalIF":1.3,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143789467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of hematologic indices in parvovirus infected dogs with systemic inflammatory response syndrome (SIRS) 评估副病毒感染犬全身炎症反应综合征（SIRS）的血液学指标。

IF 1.3 3区农林科学

Topics in companion animal medicine Pub Date : 2025-03-13 DOI: 10.1016/j.tcam.2025.100977

K. Sevim , E.Ç. Çolakoğlu , U. Kaya

{"title":"Evaluation of hematologic indices in parvovirus infected dogs with systemic inflammatory response syndrome (SIRS)","authors":"K. Sevim , E.Ç. Çolakoğlu , U. Kaya","doi":"10.1016/j.tcam.2025.100977","DOIUrl":"10.1016/j.tcam.2025.100977","url":null,"abstract":"<div><div>Canine parvoviral enteritis (CPE) is a highly contagious, acute viral disease that mainly affects young dogs and can lead to systemic inflammatory response syndrome (SIRS), sepsis, endotoxemia and even death. The study aimed to evaluate the diagnostic and prognostic potential of hematological indices such as MLR, NLR, PLR, PNR and SII in CPV-infected dogs with SIRS at first admission. The retrospective study was performed on 51 CPV-infected and 20 healthy dogs. MLR, NLR, PLR, PNR, and SII indices were determined and compared between groups. A receiver operating characteristic (ROC) curve analysis was carried out to determine thresholds of sensitivity and specificity for hematologic indices.</div><div>NLR, PLR, and PNR were the best predictors for supporting a diagnosis of parvoviral enteritis, with AUC values of 0.685, 0.762, and 0.884, respectively. Moreover, PLR and PNR, with AUC values of 0.740 and 0.769, respectively, were the most suitable indices to determine the prognosis of dogs with parvoviral enteritis with SIRS. In conclusion, these indices can be used as potential indicators for predicting disease outcomes and supporting a diagnosis of CPV-infected dogs with SIRS at first admission.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"66 ","pages":"Article 100977"},"PeriodicalIF":1.3,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143631157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0