Topics in companion animal medicine最新文献

Mammary neoplasms in male dogs: A 24-year descriptive study 雄性犬乳腺肿瘤：一项为期24年的描述性研究。

IF 1.3 3区农林科学

Topics in companion animal medicine Pub Date : 2025-05-13 DOI: 10.1016/j.tcam.2025.100980

Fernanda Freitas Miranda , Lize Amanda Basaglia Borges , Karen Yumi Ribeiro Nakagaki , Camila Costa Abreu , Geovanni Dantas Cassali

{"title":"Mammary neoplasms in male dogs: A 24-year descriptive study","authors":"Fernanda Freitas Miranda , Lize Amanda Basaglia Borges , Karen Yumi Ribeiro Nakagaki , Camila Costa Abreu , Geovanni Dantas Cassali","doi":"10.1016/j.tcam.2025.100980","DOIUrl":"10.1016/j.tcam.2025.100980","url":null,"abstract":"<div><div>Mammary neoplasms in male dogs are as rare as in humans, accounting for <1% of all tumors. In a descriptive review of cases diagnosed between 2000 and June 2024, 2,172 mammary neoplasms were identified, of which only four (0.18%) occurred in male dogs. The patients ranged in age from 8 to 11 years, with a mean age of 9.7 years. Histopathological analysis revealed that 75% (3/4) of the cases were malignant, while 25% (1/4) were benign. Among the malignant cases, only one patient exhibited regional metastases. Two patients had concurrent testicular neoplasia, both diagnosed as Leydig cell tumors. Malignant histological subtypes included carcinosarcoma, tubular carcinoma, and carcinoma within a mixed tumor. The only benign tumor identified was a benign mixed tumor. All malignant neoplasms exhibited high expression of hormone receptors, highlighting their potential role in tumor development. Additionally, cyclooxygenase-2 (COX-2) expression, a potential therapeutic target and prognostic factor, was observed. Early diagnosis is crucial for improving prognosis; however, due to the rarity of this condition, diagnosis is often delayed. These findings emphasize the occurrence of these neoplasms in male dogs, and report on complementary techniques to improve therapeutic strategies.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"67 ","pages":"Article 100980"},"PeriodicalIF":1.3,"publicationDate":"2025-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144083112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nosocomial transmission of Sporothrix brasiliensis in two cats 巴西孢子丝菌在两只猫中的医院传播

IF 1.3 3区农林科学

Topics in companion animal medicine Pub Date : 2025-05-01 DOI: 10.1016/j.tcam.2025.100979

Rafael Gariglio Clark Xavier, Salene Angelini Colombo, Brendhal Almeida Silva, Jéssica Rabelo de Oliveira Persichini, Gabriele Silva Duarte, João Victor Ferreira Campos, Rodrigo Otávio Silveira Silva, Maria Isabel de Azevedo

{"title":"Nosocomial transmission of Sporothrix brasiliensis in two cats","authors":"Rafael Gariglio Clark Xavier, Salene Angelini Colombo, Brendhal Almeida Silva, Jéssica Rabelo de Oliveira Persichini, Gabriele Silva Duarte, João Victor Ferreira Campos, Rodrigo Otávio Silveira Silva, Maria Isabel de Azevedo","doi":"10.1016/j.tcam.2025.100979","DOIUrl":"10.1016/j.tcam.2025.100979","url":null,"abstract":"<div><div>Sporotrichosis is a neglected zoonotic infection caused by pathogenic <em>Sporothrix</em> species, primarily affecting the skin and lymphatic system but occasionally leading to life-threatening systemic disease in some cases. Brazil bears the highest global burden of cat and human sporotrichosis. Transmission mainly occurs through traumatic inoculation of the fungus via cat bites, scratches, thorns, or wooden splinters. To date, nosocomial transmission of <em>Sporothrix spp.</em> has not been reported. This report describes two cases of healthcare-associated sporotrichosis in cats in Belo Horizonte (Minas Gerais, Brazil). Both animals (cases 1 and 2) underwent trichotomy at two different veterinary clinics, with both undergoing abdominal ultrasound examination and one (case 2) receiving further venous access. Small skin lesions caused by the trichotomy presented with purulent content approximately six days after the procedure. Samples from the cutaneous lesions were collected and subjected to cytological examination and mycological culture. <em>S. brasiliensis</em> was confirmed through species-specific PCR and calmodulin (<em>CAL</em>) gene sequencing. Phylogenetic analysis revealed that both isolates clustered with clinical <em>S. brasiliensis</em> isolates extracted from infected cats, dogs, and humans in Brazil. These findings highlight the potential for <em>S. brasiliensis</em> transmission through contaminated fur clippers in veterinary hospitals, underscoring the risk of nosocomial infection in animals.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"66 ","pages":"Article 100979"},"PeriodicalIF":1.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143946901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metagenomic and 16S rRNA analysis of culture-negative uterine samples identifies Brucella spp. in a female dog with pyometra

IF 1.3 3区农林科学

Topics in companion animal medicine Pub Date : 2025-05-01 DOI: 10.1016/j.tcam.2025.100981

Rafael Gariglio Clark Xavier , Clarissa Helena Santana , Yasmin Gonçalves de Castro , Rodrigo Dias de Oliveira Carvalho , Tales Fernando da Silva , Vasco Azevedo , Flávia Figueira Aburjaile , Elaine Maria Seles Dorneles , Renato Lima Santos , Rodrigo Otávio Silveira Silva

{"title":"Metagenomic and 16S rRNA analysis of culture-negative uterine samples identifies Brucella spp. in a female dog with pyometra","authors":"Rafael Gariglio Clark Xavier , Clarissa Helena Santana , Yasmin Gonçalves de Castro , Rodrigo Dias de Oliveira Carvalho , Tales Fernando da Silva , Vasco Azevedo , Flávia Figueira Aburjaile , Elaine Maria Seles Dorneles , Renato Lima Santos , Rodrigo Otávio Silveira Silva","doi":"10.1016/j.tcam.2025.100981","DOIUrl":"10.1016/j.tcam.2025.100981","url":null,"abstract":"<div><div>Canine pyometra is the most prevalent reproductive disease in female dogs and involves a complex interplay of hormonal and microbial factors. Although <em>Enterobacteriaceae</em> are known to be the main cause of pyometra, up to 25 % of samples remain negative when classic culture methods are used. The lack of growth in conventional media raises the intriguing possibility that non-cultivable microorganisms participate in the disease. Our study aimed to address this knowledge gap by investigating the microbiota in culture-negative uterine samples from dogs with pyometra. The purulent uterine contents of dogs with pyometra (<em>n</em> = 79) were subjected to bacterial culture. Most of the samples showed bacterial growth of <em>Escherichia coli</em> (48/79, 60.7 %) or other bacterial species (25/79, 31.8 %). Samples that tested negative using the classic culture method (6/79=7.5 %) were further analyzed using 16S rRNA gene sequencing, high-throughput 16S rRNA sequencing, and shotgun metagenomics. Only three of these provided DNA of sufficient quality for further analysis, which revealed a mixture of <em>Haemophilus</em>/<em>Aggregatibacter</em> and <em>Fusobacterium</em>/<em>Porphyromonas</em> in two uterine content. In the third sample, <em>Brucella</em> spp. was identified as the main genus. This study suggests that pathogens that are not easily isolated by classical culture methods, including zoonotic species, may be present in the uterus of dogs with pyometra.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"66 ","pages":"Article 100981"},"PeriodicalIF":1.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143942998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surgical stabilization of a mandibular fracture in a pet African goose (Anser anser domesticus) with bilateral mandibular fractures 宠物非洲鹅（Anser Anser domesticus）双侧下颌骨骨折手术稳定。

IF 1.3 3区农林科学

Topics in companion animal medicine Pub Date : 2025-04-03 DOI: 10.1016/j.tcam.2025.100978

Seunga Min , Miranda J. Sadar , Taylr Wells , Amanda Day , Naomi Hoyer

{"title":"Surgical stabilization of a mandibular fracture in a pet African goose (Anser anser domesticus) with bilateral mandibular fractures","authors":"Seunga Min , Miranda J. Sadar , Taylr Wells , Amanda Day , Naomi Hoyer","doi":"10.1016/j.tcam.2025.100978","DOIUrl":"10.1016/j.tcam.2025.100978","url":null,"abstract":"<div><div>A 7-month-old, 3.8 kg, female intact African goose (<em>Anser anser domesticus</em>), was presented on emergency after being struck by a metal chair during a strong gust of wind. Physical examination revealed ventral displacement of rostral portion of the mandible. A cone beam computed tomography (CBCT) scan confirmed complete, comminuted, bilateral fractures on the rostral portion of the mandibular body. Surgical intervention involved applying external fixation using self-threading Thread Mate System (TMS) pins, orthodontic chains, and dental acrylics to stabilize the right mandible. Indirect reduction and inherent stability were achieved on the left side. An esophagostomy tube was placed to prevent manipulation of the bill during feeding and medication administration in the post operative period. The goose prematurely removed the esophagostomy tube and dental acrylics 10 days after surgery. At the two week post-operative recheck, the bill was stable on palpation and the goose was using it for eating and drinking without complications. At follow-up examination one month after surgery, the goose continued to clinically do well, but all fixations had been self-removed. A repeat CBCT scan revealed bony callus formation of the left fracture site and fibrous callus with incomplete osseous bridging of the right fracture site consistent with delayed union. At 8 months post-operatively, the goose was clinically normal without functional impairment to the bill.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"66 ","pages":"Article 100978"},"PeriodicalIF":1.3,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143789467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of hematologic indices in parvovirus infected dogs with systemic inflammatory response syndrome (SIRS) 评估副病毒感染犬全身炎症反应综合征（SIRS）的血液学指标。

IF 1.3 3区农林科学

Topics in companion animal medicine Pub Date : 2025-03-13 DOI: 10.1016/j.tcam.2025.100977

K. Sevim , E.Ç. Çolakoğlu , U. Kaya

{"title":"Evaluation of hematologic indices in parvovirus infected dogs with systemic inflammatory response syndrome (SIRS)","authors":"K. Sevim , E.Ç. Çolakoğlu , U. Kaya","doi":"10.1016/j.tcam.2025.100977","DOIUrl":"10.1016/j.tcam.2025.100977","url":null,"abstract":"<div><div>Canine parvoviral enteritis (CPE) is a highly contagious, acute viral disease that mainly affects young dogs and can lead to systemic inflammatory response syndrome (SIRS), sepsis, endotoxemia and even death. The study aimed to evaluate the diagnostic and prognostic potential of hematological indices such as MLR, NLR, PLR, PNR and SII in CPV-infected dogs with SIRS at first admission. The retrospective study was performed on 51 CPV-infected and 20 healthy dogs. MLR, NLR, PLR, PNR, and SII indices were determined and compared between groups. A receiver operating characteristic (ROC) curve analysis was carried out to determine thresholds of sensitivity and specificity for hematologic indices.</div><div>NLR, PLR, and PNR were the best predictors for supporting a diagnosis of parvoviral enteritis, with AUC values of 0.685, 0.762, and 0.884, respectively. Moreover, PLR and PNR, with AUC values of 0.740 and 0.769, respectively, were the most suitable indices to determine the prognosis of dogs with parvoviral enteritis with SIRS. In conclusion, these indices can be used as potential indicators for predicting disease outcomes and supporting a diagnosis of CPV-infected dogs with SIRS at first admission.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"66 ","pages":"Article 100977"},"PeriodicalIF":1.3,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143631157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dermal pathology in a Catahoula Leopard dog with Dermasparaxis Ehlers Danlos syndrome caused by a homozygous ADAMTS2 missense variant 由纯合子ADAMTS2错义变异引起的皮肤paraxis Ehlers Danlos综合征的Catahoula豹犬的皮肤病理。

IF 1.3 3区农林科学

Topics in companion animal medicine Pub Date : 2025-03-12 DOI: 10.1016/j.tcam.2025.100976

Jared A. Jaffey , Garrett Bullock , Martin L. Katz

{"title":"Dermal pathology in a Catahoula Leopard dog with Dermasparaxis Ehlers Danlos syndrome caused by a homozygous ADAMTS2 missense variant","authors":"Jared A. Jaffey , Garrett Bullock , Martin L. Katz","doi":"10.1016/j.tcam.2025.100976","DOIUrl":"10.1016/j.tcam.2025.100976","url":null,"abstract":"<div><div>Dermatosparaxis is a subtype of Ehlers-Danlos syndrome (dEDS) that typically results in euthanasia of dogs in the first several months of life because of complications mostly related to extreme skin fragility. The goal of this report was to describe ultrastructural features of collagen fibrils from a dog with a milder form of dEDS. A skin biopsy sample was procured from a nearly 10-year-old Catahoula Leopard dog with dEDS associated with a previously published homozygous missense variant in <em>ADAMTS2</em>. Light and electron microscopic examinations were performed. Light microscopic examination of the skin sample revealed a substantially reduced density of collagen fibers that were randomly oriented and appeared to have a decreased length. Electron microscopic examination revealed diameters of the fibrils were variable, and scattered fibrils had irregular cross-sectional profiles, but lacked the “hieroglyphic” appearance identified in dogs with the frameshift variant in <em>ADAMTS2</em>. Like other species with dEDS, dogs can have variable disease severities that includes dermal collagen abnormalities.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"66 ","pages":"Article 100976"},"PeriodicalIF":1.3,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143631156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Case series of maggot debridement therapy demonstrates safety and efficacy for treating problematic wounds in cats and dogs in Mexico 在墨西哥，蛆虫清创疗法证明了治疗猫和狗的问题伤口的安全性和有效性。

IF 1.3 3区农林科学

Topics in companion animal medicine Pub Date : 2025-03-11 DOI: 10.1016/j.tcam.2025.100964

Alicia Fonseca-Muñoz , Aremí C. Lujano-Guzmán , Albert Nguyen , Ronald A. Sherman

{"title":"Case series of maggot debridement therapy demonstrates safety and efficacy for treating problematic wounds in cats and dogs in Mexico","authors":"Alicia Fonseca-Muñoz , Aremí C. Lujano-Guzmán , Albert Nguyen , Ronald A. Sherman","doi":"10.1016/j.tcam.2025.100964","DOIUrl":"10.1016/j.tcam.2025.100964","url":null,"abstract":"<div><div>Wound care is a common problem in small animals. Antimicrobial resistance, biofilm, time constraints, and the cost of surgery or specialized dressings hinder efforts to deliver prompt wound healing. Maggot therapy has been very effective in human and equine wound care, but very little research has evaluated its safety and efficacy in dogs and cats. This study was initiated to evaluate the utility, efficacy, and safety of maggot debridement therapy for wound care in a small animal veterinary practice in Mexico.</div><div>Six cats and four dogs were treated with maggot debridement therapy when their wounds failed to respond to conventional therapy. Treatment was administered by applying 8-10 larvae per cm<sup>2</sup> surface area directly on the wound bed and covering the wound with a sterile polyester mesh, sutured to the skin. These were left on the wound for cycles of approximately 48 h (24-72 h); the cycles were repeated if >20 % necrotic tissue remained after treatment.</div><div>Review of these cases revealed that 80 % of treated wounds achieved 100 % debridement within 48-96 h of treatment. An additional 10 % (one wound) achieved 80 % debridement within only 24 h of treatment. One animal failed to show improvement: a 3-year-old cat with an infected bite wound, which drained voluminously and drowned the maggots. This animal was deemed not to be an appropriate candidate for maggot debridement therapy, and treatment was terminated after just 12 h. Ultimately, this wound was debrided and closed surgically. No complications were encountered other than mild discomfort in one cat.</div><div>These results support claims that maggot debridement therapy is relatively safe and effective for treating problematic dog and cat wounds. Veterinarians should consider including maggot debridement among their treatment options for problematic wounds. Controlled clinical trials should be performed.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"66 ","pages":"Article 100964"},"PeriodicalIF":1.3,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143627289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characterization of Rhodococcus equi isolated from pyogranulomatous lesions in cats from Brazil 巴西猫脓肉芽肿性病变中分离的马红球菌的鉴定。

IF 1.3 3区农林科学

Topics in companion animal medicine Pub Date : 2025-03-01 DOI: 10.1016/j.tcam.2025.100962

Jamilly Rosa dos Santos , Renata Dalcol Mazaro , Alana Pivoto Herbichi , Rafael Almeida Fighera , Andrea Maria Lazzari , Sabrina dos Santos Costa Poggiani , Agueda Palmira Castagna de Vargas , Fernanda Silveira Flores Vogel , Juliana Felipetto Cargnelutti

{"title":"Characterization of Rhodococcus equi isolated from pyogranulomatous lesions in cats from Brazil","authors":"Jamilly Rosa dos Santos , Renata Dalcol Mazaro , Alana Pivoto Herbichi , Rafael Almeida Fighera , Andrea Maria Lazzari , Sabrina dos Santos Costa Poggiani , Agueda Palmira Castagna de Vargas , Fernanda Silveira Flores Vogel , Juliana Felipetto Cargnelutti","doi":"10.1016/j.tcam.2025.100962","DOIUrl":"10.1016/j.tcam.2025.100962","url":null,"abstract":"<div><div>This study aimed to describe and provide a laboratory characterization of three cases of <em>Rhodococcus equi</em> isolates from pyogranulomatous lesions in domestic cats in Brazil, collected between 2015 and 2021. Swabs and aspirates from nodular skin lesions located in the abdominal region (Case 1) and thoracic limbs (Cases 1–3) were subjected to microbiological culture, biochemical and molecular analyses, evaluation of biofilm formation capacity, and antimicrobial sensitivity testing. Cats 1 and 2 were positive for FeLV p27 antigen on SNAP testing. Cat 1 died at home from complications of <em>Rhodococcus</em> infection, and Cat 2 was euthanized following failure of medical and surgical treatment of infection. The cat in Case 3, which was FeLV-negative, received treatment with oral erythromycin and topical rifampicin for 30 days. However, due to failure of antimicrobial therapy to resolve the lesions, the cat underwent amputation of the affected right hindlimb. <em>R. equi,</em> positive for the plasmid-encoded virulence-associated protein A, was identified on the microbiological cultures and PCR from all cases. Biofilm formation analysis categorized all three isolates as weak biofilm formers. Additionally, antimicrobial susceptibility testing revealed that all isolates were sensitive to azithromycin, clarithromycin, erythromycin, imipenem, and rifampicin in vitro. These findings underscore the clinical, epidemiological, and laboratory characteristics of <em>R. equi</em> infection in Brazilian cats, indicating that these microorganisms are phenotypically and molecularly similar to those isolated from horses.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"65 ","pages":"Article 100962"},"PeriodicalIF":1.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143485229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of the effects of an opioid-free anesthetic protocol with two opioid-based protocols on the intraoperative cardiovascular response and postoperative pain in cats undergoing elective ovariohysterectomy: A prospective, randomized, blinded, clinical study 比较无阿片麻醉方案和两种阿片麻醉方案对接受择期卵巢切除术的猫术中心血管反应和术后疼痛的影响：一项前瞻性、随机、盲法临床研究。

IF 1.3 3区农林科学

Topics in companion animal medicine Pub Date : 2025-03-01 DOI: 10.1016/j.tcam.2025.100963

Bárbara Silva Correia, Eduardo Raposo Monteiro, João Victor Barbieri Ferronatto, Ivy Silva de La Rocque Pinho, Lívia Eichenberg Surita, Marcelo Meller Alievi

{"title":"Comparison of the effects of an opioid-free anesthetic protocol with two opioid-based protocols on the intraoperative cardiovascular response and postoperative pain in cats undergoing elective ovariohysterectomy: A prospective, randomized, blinded, clinical study","authors":"Bárbara Silva Correia, Eduardo Raposo Monteiro, João Victor Barbieri Ferronatto, Ivy Silva de La Rocque Pinho, Lívia Eichenberg Surita, Marcelo Meller Alievi","doi":"10.1016/j.tcam.2025.100963","DOIUrl":"10.1016/j.tcam.2025.100963","url":null,"abstract":"<div><div>This study compared the cardiovascular response to surgery and postoperative pain between an opioid-free protocol and two opioid-based protocols in cats undergoing elective ovariohysterectomy. Cats were randomly allocated into three intramuscular premedication treatments: DEX (dexmedetomidine 7 µg/kg, <em>n</em> = 12), DEXMET (dexmedetomidine 7 µg/kg + methadone 0.3 mg/kg, <em>n</em> = 13) and DEXMOR (dexmedetomidine 7 µg/kg + morphine 0.3 mg/kg, <em>n</em> = 14). Preoperatively, all cats received meloxicam 0.1 mg/kg, subcutaneously. Anesthesia was induced with propofol and maintained with sevoflurane. Heart rate (HR) and systolic arterial pressure (SAP) were measured intraoperatively. Pain was assessed before premedication (Baseline) and postoperatively for 6 h using the Glasgow Composite Measure Pain Scale - Feline (CMPS-F) and Feline Grimace Scale (FGS). Rescue analgesia was given for CMPS-F scores ≥ 5.</div><div>In all groups, HR and SAP increased intraoperatively, but tachycardia (HR > 200 beats/min) or hypertension (SAP > 180 mmHg) did not occur. Postoperative CMPS-F scores were lower in DEXMET than in DEX; FGS scores in DEX and DEXMOR were higher than in DEXMET. Rescue analgesia was administered to 50 %, 23 % and 29 % cats in groups DEX, DEXMET and DEXMOR, respectively (<em>p</em> > 0.05). The odds ratio (95 % confidence interval) of receiving postoperative rescue analgesia within 6 h for opioid-free <em>versus</em> opioid-based techniques was 2.86 (0.76-11.43). All protocols allowed surgery to be performed without an exacerbated cardiovascular response. Incorporating methadone or morphine in the protocol decreased the odds of requiring postoperative rescue analgesia.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"65 ","pages":"Article 100963"},"PeriodicalIF":1.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143485230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cryptorchidism in dogs and cats presented for elective gonadectomy: A descriptive cohort study of 306 animals treated between 2018 and 2023 选择性性腺切除术中出现的狗和猫隐睾：一项描述性队列研究，对2018年至2023年间治疗的306只动物进行了研究。

IF 1.3 3区农林科学

Topics in companion animal medicine Pub Date : 2025-03-01 DOI: 10.1016/j.tcam.2025.100961

Seong Eun Cho , James M. Fudge , Suhee Kim , Bernie Page , DoHyeon Yu

{"title":"Cryptorchidism in dogs and cats presented for elective gonadectomy: A descriptive cohort study of 306 animals treated between 2018 and 2023","authors":"Seong Eun Cho , James M. Fudge , Suhee Kim , Bernie Page , DoHyeon Yu","doi":"10.1016/j.tcam.2025.100961","DOIUrl":"10.1016/j.tcam.2025.100961","url":null,"abstract":"<div><div>The objective of this study was to describe the incidence, breed distribution, clinical findings (anatomic location, number of testicles affected, and side), and surgical management of cryptorchidism in dogs and cats presented for elective gonadectomy. Medical record abstracts from a non-profit, high-volume, high-quality, spay-neuter clinic from 2018 to 2023 were reviewed retrospectively for cases of elective surgical gonadectomy of cryptorchid dogs and cats. During the study period, 5,476 dogs and 11,559 cats were presented to the same facility for elective surgical castration, suggesting a cryptorchid incidence of 3.21 % for dogs and 1.12 % for cats. Cryptorchidism affects various breeds and body conformations. Cryptorchid testes were more commonly observed in the inguinal area than in the abdomen, and were more frequently located unilaterally on the right side in both dogs and cats. The mean number of overall incisions required for surgical management was higher for testes located in the abdomen than for those located in the inguinal region in both dogs and cats. Due to differences in anatomy, cryptorchid prevalence, and surgical techniques, cryptorchidism in dogs and cats should be evaluated separately. Careful, preemptive identification and localization of the retained testicle(s) can be beneficial for efficient excision of cryptorchid testes.</div></div>","PeriodicalId":23144,"journal":{"name":"Topics in companion animal medicine","volume":"65 ","pages":"Article 100961"},"PeriodicalIF":1.3,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143485231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0