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A novel allele, HLA-A*110203, was identified in a Chinese individual. 一种新的等位基因HLA-A*110203在中国个体中被鉴定出来。
Tissue antigens Pub Date : 2009-11-01 DOI: 10.1111/j.1399-0039.2009.01338.x
Z Li, H-Y Zou, D-M Wang, X Cheng
{"title":"A novel allele, HLA-A*110203, was identified in a Chinese individual.","authors":"Z Li,&nbsp;H-Y Zou,&nbsp;D-M Wang,&nbsp;X Cheng","doi":"10.1111/j.1399-0039.2009.01338.x","DOIUrl":"https://doi.org/10.1111/j.1399-0039.2009.01338.x","url":null,"abstract":"<p><p>This allele is characterized by a nucleotide substitution (C>T) in exon 4 at position nt 672, codon 200 (ACC>ACT), no coding change.</p>","PeriodicalId":23105,"journal":{"name":"Tissue antigens","volume":"74 5","pages":"434-5"},"PeriodicalIF":0.0,"publicationDate":"2009-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1399-0039.2009.01338.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28449422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
The predicted protein structures of the novel DRB1*0717 and DRB1*0701 are highly related. 预测的DRB1*0717蛋白结构与DRB1*0701蛋白结构高度相关。
Tissue antigens Pub Date : 2009-11-01 DOI: 10.1111/j.1399-0039.2009.01348.x
M Wurm, S Tischer, S Immenschuh, R Blasczyk, B Eiz-Vesper
{"title":"The predicted protein structures of the novel DRB1*0717 and DRB1*0701 are highly related.","authors":"M Wurm,&nbsp;S Tischer,&nbsp;S Immenschuh,&nbsp;R Blasczyk,&nbsp;B Eiz-Vesper","doi":"10.1111/j.1399-0039.2009.01348.x","DOIUrl":"https://doi.org/10.1111/j.1399-0039.2009.01348.x","url":null,"abstract":"<p><p>This article describes the identification of the novel human leukocyte antigen (HLA) allele DRB1*07 7 that was detected in a potential stem-cell donor of Caucasian origin. Compared to DRB1*070101, the new allele is characterized by a nonsynonymous nucleotide exchange of C-->T at position 201 in exon 2 replacing Arg by Trp in codon 72. As this sequence variation has not been seen earlier in any other HLA-DRB allele, it is most probably the result of a point mutation.</p>","PeriodicalId":23105,"journal":{"name":"Tissue antigens","volume":"74 5","pages":"460-2"},"PeriodicalIF":0.0,"publicationDate":"2009-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1399-0039.2009.01348.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28449430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
The novel HLA-G*01010302 allele differs from G*01010301 by a single nucleotide change in intron 5. 新的HLA-G*01010302等位基因与G*01010301的不同之处在于内含子5的单个核苷酸变化。
Tissue antigens Pub Date : 2009-11-01 DOI: 10.1111/j.1399-0039.2009.01363.x
I Cervera, M A Herraiz, A Román, J Vidart, J Martinez-Laso
{"title":"The novel HLA-G*01010302 allele differs from G*01010301 by a single nucleotide change in intron 5.","authors":"I Cervera,&nbsp;M A Herraiz,&nbsp;A Román,&nbsp;J Vidart,&nbsp;J Martinez-Laso","doi":"10.1111/j.1399-0039.2009.01363.x","DOIUrl":"https://doi.org/10.1111/j.1399-0039.2009.01363.x","url":null,"abstract":"<p><p>HLA-G*01010301 and G*01010302 differ by a single point mutation in intron 5.</p>","PeriodicalId":23105,"journal":{"name":"Tissue antigens","volume":"74 5","pages":"463-4"},"PeriodicalIF":0.0,"publicationDate":"2009-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1399-0039.2009.01363.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28449431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Five novel HLA-A alleles, HLA-A*030108, A*2491, A*2498, A*330303, A*3317 were identified by polymerase chain reaction sequence based typing. 采用聚合酶链反应序列分型，鉴定出HLA-A*030108、A*2491、A*2498、A*330303、A*3317 5个新的HLA-A等位基因。
Tissue antigens Pub Date : 2009-11-01 DOI: 10.1111/j.1399-0039.2009.01358.x
L-X Yan, F-M Zhu, J He, W Zhang
{"title":"Five novel HLA-A alleles, HLA-A*030108, A*2491, A*2498, A*330303, A*3317 were identified by polymerase chain reaction sequence based typing.","authors":"L-X Yan,&nbsp;F-M Zhu,&nbsp;J He,&nbsp;W Zhang","doi":"10.1111/j.1399-0039.2009.01358.x","DOIUrl":"https://doi.org/10.1111/j.1399-0039.2009.01358.x","url":null,"abstract":"<p><p>Five HLA-A variant alleles HLA-A*030108, A*2491, A*2498, A*330303, A*3317 were identified in Chinese individuals.</p>","PeriodicalId":23105,"journal":{"name":"Tissue antigens","volume":"74 5","pages":"432-4"},"PeriodicalIF":0.0,"publicationDate":"2009-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1399-0039.2009.01358.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28449421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 17
Human neutrophil alloantigen-1a, -1b, -2, -3a and -4a frequencies in Brazilians. 巴西人中性粒细胞异体抗原1a、-1b、-2、-3a和-4a频率。
Tissue antigens Pub Date : 2009-11-01 Epub Date: 2009-09-08 DOI: 10.1111/j.1399-0039.2009.01357.x
A M M I Norcia, E Y K Sugano, A K Chiba, E Moritz, F P Guirao, M Yamamoto, J O Bordin
{"title":"Human neutrophil alloantigen-1a, -1b, -2, -3a and -4a frequencies in Brazilians.","authors":"A M M I Norcia,&nbsp;E Y K Sugano,&nbsp;A K Chiba,&nbsp;E Moritz,&nbsp;F P Guirao,&nbsp;M Yamamoto,&nbsp;J O Bordin","doi":"10.1111/j.1399-0039.2009.01357.x","DOIUrl":"https://doi.org/10.1111/j.1399-0039.2009.01357.x","url":null,"abstract":"<p><p>Human neutrophil reactive antibodies may cause clinical disorders such as transfusion-related acute lung injury, febrile transfusion reactions, alloimmune neonatal neutropenia, immune neutropenia after stem cell transplantation, refractoriness to granulocyte transfusion, drug-induced neutropenia and autoimmune neutropenia. Using the granulocyte immunofluorescence test by flow cytometry, the phenotypic frequencies of the human neutrophil alloantigens (HNA)-1a, -1b, -2, -3a and -4a were determined in 100 healthy Brazilian persons. Neutrophils were separated from blood samples by sedimentation, centrifugated and incubated with HNA-specific alloantibody plus fluorescein isothiocyanate-labeled F(ab')(2) fragments of anti-human IgG. The results showed that the phenotype frequencies of HNA-1a, -1b, -2a, -3a and -4a were 65%, 83%, 97%, 95% and 94%, respectively. We detected that neutrophils from 17% of Brazilians typed positive only with anti-HNA-1a (HNA-1a/a), 35% only with anti-HNA-1b (HNA-1b/b) and 48% reacted with both antibodies (HNA-1a/b). The frequencies found for HNA-1a and -1b were quite similar to that reported among Africans and American-Africans, but different from those found in Japanese and Chinese. In addition, our data showed that the frequencies of HNA-2, -3a and -4a in Brazilians were comparable with those observed in Caucasians. The determination of HNAs frequencies among populations with distinct racial backgrounds is important not only for anthropological reasons, but also for neonatal typing in suspected cases of alloimmune neutropenia or when patients are severely neutropenic.</p>","PeriodicalId":23105,"journal":{"name":"Tissue antigens","volume":"74 5","pages":"404-7"},"PeriodicalIF":0.0,"publicationDate":"2009-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1399-0039.2009.01357.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28389259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 15
A novel HLA-Cw*04 allele, Cw*04010103, identified by genomic full length cloning and sequencing. 通过克隆和测序，鉴定出一个新的HLA-Cw*04等位基因Cw*04010103。
Tissue antigens Pub Date : 2009-11-01 Epub Date: 2009-09-08 DOI: 10.1111/j.1399-0039.2009.01353.x
Y Xu, Z Deng, J Zeng, S Gao, D Wang
{"title":"A novel HLA-Cw*04 allele, Cw*04010103, identified by genomic full length cloning and sequencing.","authors":"Y Xu,&nbsp;Z Deng,&nbsp;J Zeng,&nbsp;S Gao,&nbsp;D Wang","doi":"10.1111/j.1399-0039.2009.01353.x","DOIUrl":"https://doi.org/10.1111/j.1399-0039.2009.01353.x","url":null,"abstract":"<p><p>A novel human leukocyte antigen-Cw*04 allele, Cw*04010103, was identified by genomic full length cloning and sequencing from a male Chinese donor. It differs from the closest related allele Cw*04010101 by one nucleotide exchange at nt 1111 (G>A) in intron 3.</p>","PeriodicalId":23105,"journal":{"name":"Tissue antigens","volume":"74 5","pages":"453-5"},"PeriodicalIF":0.0,"publicationDate":"2009-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1399-0039.2009.01353.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28389260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
IL7RA polymorphisms and chronic inflammatory arthropathies. IL7RA多态性与慢性炎性关节病。
Tissue antigens Pub Date : 2009-11-01 Epub Date: 2009-09-08 DOI: 10.1111/j.1399-0039.2009.01342.x
C O'Doherty, I Alloza, M Rooney, K Vandenbroeck
{"title":"IL7RA polymorphisms and chronic inflammatory arthropathies.","authors":"C O'Doherty,&nbsp;I Alloza,&nbsp;M Rooney,&nbsp;K Vandenbroeck","doi":"10.1111/j.1399-0039.2009.01342.x","DOIUrl":"https://doi.org/10.1111/j.1399-0039.2009.01342.x","url":null,"abstract":"<p><p>The C allele of a single nucleotide polymorphism (SNP), rs6897932, located in the interleukin-7 receptor alpha chain (IL7RA) was recently found to be associated with multiple sclerosis and Type I diabetes. We analysed 13 SNPs in the IL7RA gene in a combined cohort of patients with chronic inflammatory arthropathies (rheumatoid arthritis and juvenile idiopathic arthritis; 368 patients and 532 unaffected subjects). No significant associations with disease were found with the exception of the non-synonymous SNP rs6897932. This SNP showed modest enrichment of the TT genotype in arthritic patients compared with controls [P = 0.02; OR 1.72 (95% CI 1.08-2.75)]. Our data are suggestive for a role of rs6897932 in predisposition to chronic inflammatory arthropathies.</p>","PeriodicalId":23105,"journal":{"name":"Tissue antigens","volume":"74 5","pages":"429-31"},"PeriodicalIF":0.0,"publicationDate":"2009-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1399-0039.2009.01342.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28393864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 41
A novel HLA-B allele: HLA-B*5419. 新的HLA-B等位基因:HLA-B*5419。
Tissue antigens Pub Date : 2009-11-01 DOI: 10.1111/j.1399-0039.2009.01356.x
K W Lee, J J Seo
{"title":"A novel HLA-B allele: HLA-B*5419.","authors":"K W Lee,&nbsp;J J Seo","doi":"10.1111/j.1399-0039.2009.01356.x","DOIUrl":"https://doi.org/10.1111/j.1399-0039.2009.01356.x","url":null,"abstract":"<p><p>B*5419 differs from B*5401 by a single nucleotide substitution at codon 13 (TCC --> TTC).</p>","PeriodicalId":23105,"journal":{"name":"Tissue antigens","volume":"74 5","pages":"444-5"},"PeriodicalIF":0.0,"publicationDate":"2009-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1399-0039.2009.01356.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28449426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Cloning and sequencing analysis of a novel HLA-Cw*08 variant allele, Cw*0827. HLA-Cw*08变异等位基因Cw*0827的克隆与测序分析。
Tissue antigens Pub Date : 2009-11-01 DOI: 10.1111/j.1399-0039.2009.01354.x
Z-H Deng, D-M Wang, Y-P Xu
{"title":"Cloning and sequencing analysis of a novel HLA-Cw*08 variant allele, Cw*0827.","authors":"Z-H Deng,&nbsp;D-M Wang,&nbsp;Y-P Xu","doi":"10.1111/j.1399-0039.2009.01354.x","DOIUrl":"https://doi.org/10.1111/j.1399-0039.2009.01354.x","url":null,"abstract":"<p><p>The novel HLA-Cw*0827 variant allele differs from the closest allele Cw*0802 by five nucleotide changes.</p>","PeriodicalId":23105,"journal":{"name":"Tissue antigens","volume":"74 5","pages":"458-60"},"PeriodicalIF":0.0,"publicationDate":"2009-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1399-0039.2009.01354.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28449429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Genomic full length sequence of HLA-Cw*030301, identified by cloning and sequencing. HLA-Cw*030301基因组全长序列，经克隆和测序鉴定。
Tissue antigens Pub Date : 2009-11-01 Epub Date: 2009-09-18 DOI: 10.1111/j.1399-0039.2009.01352.x
Y Xu, Z Deng, J Zeng, S Gao, B Yang
{"title":"Genomic full length sequence of HLA-Cw*030301, identified by cloning and sequencing.","authors":"Y Xu,&nbsp;Z Deng,&nbsp;J Zeng,&nbsp;S Gao,&nbsp;B Yang","doi":"10.1111/j.1399-0039.2009.01352.x","DOIUrl":"https://doi.org/10.1111/j.1399-0039.2009.01352.x","url":null,"abstract":"<p><p>Genomic full length sequence of human leukocyte antigen (HLA)-Cw*030301 that differs from Cw*030401 by two-nucleotide exchange at nt 473 (G>A) in exon 2 and nt 3033 (G>C) in 3'UTR, was identified by cloning and sequencing from a male Chinese donor.</p>","PeriodicalId":23105,"journal":{"name":"Tissue antigens","volume":"74 5","pages":"452-3"},"PeriodicalIF":0.0,"publicationDate":"2009-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1111/j.1399-0039.2009.01352.x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"28409285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
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