The Open Biology Journal最新文献_第2页

Role of Genes and Treatments for Parkinson’s Disease 帕金森病的基因作用和治疗

The Open Biology Journal Pub Date : 2020-10-15 DOI: 10.2174/1874196702008010047

Falaq Naz, Y. Siddique

引用次数: 2

Genetic Diversity of Two Tilapia Species (Oreochromis Niloticus and Sarthrodon Galilaeus) Using Random Amplified Polymorphic DNA 两种罗非鱼(nilochromis和Sarthrodon Galilaeus)随机扩增多态性DNA的遗传多样性

The Open Biology Journal Pub Date : 2020-09-25 DOI: 10.2174/1874196702008010022

O. M. Omer, A. H. Abdalla, Z. Mahmoud

引用次数: 1

Human Brain Disorders: A Review 人类大脑疾病:综述

The Open Biology Journal Pub Date : 2020-09-25 DOI: 10.2174/1874196702008010006

Falaq Naz, Y. Siddique

引用次数: 3

Different Effects of Fluoxetine and Paroxetine Combined with Vitamin D3 in Ovariectomized Rats Exposed to Unpredictable Stress 氟西汀和帕罗西汀联合维生素D3对暴露于不可预测压力下的去卵巢大鼠的不同影响

The Open Biology Journal Pub Date : 2020-09-23 DOI: 10.2174/1874196702008010029

J. Fedotova

引用次数: 1

Overview of Advances in the Pathophysiology and Treatment of Stroke: A New Plan for Stroke Treatment 脑卒中的病理生理学和治疗进展综述:脑卒中治疗的新方案

The Open Biology Journal Pub Date : 2019-11-28 DOI: 10.2174/1874196701907010039

H. Famitafreshi, M. Karimian

引用次数: 0

Morphometric Measurements, Meristic Counts, and Molecular Identification of Alestes Dentex, Alestes Baremoze, Brycinus Nurse, and Brycinus macrolepidotus from the River Nile at Kreima 尼罗河克雷玛地区长齿Brycinus Dentex, Alestes Baremoze, Brycinus Nurse和macrolepidotus的形态测量、分生计数和分子鉴定

The Open Biology Journal Pub Date : 2019-08-30 DOI: 10.2174/1874196701907010025

A. T. M. Mohammed, Z. Mahmoud, H. M. Abushama

{"title":"Morphometric Measurements, Meristic Counts, and Molecular Identification of Alestes Dentex, Alestes Baremoze, Brycinus Nurse, and Brycinus macrolepidotus from the River Nile at Kreima","authors":"A. T. M. Mohammed, Z. Mahmoud, H. M. Abushama","doi":"10.2174/1874196701907010025","DOIUrl":"https://doi.org/10.2174/1874196701907010025","url":null,"abstract":"\u0000 \u0000 Twenty-two morphometric characters and seven meristic counts were recorded from 324 Alestes specimens from Kreima at the River Nile.\u0000 \u0000 \u0000 \u0000 Specimens collected were identified to the species level as Alestes baremoze (100 specimens), Brycinus nurse (100 specimens), Brycinus macrolepidotus (24 specimens), and Alestes dentex (100 specimens). The principal component analysis showed that the lateral line scales and the scale above the lateral line contributed to the percentage variance by 97.01% and 2.56%, respectively. Discriminant function analysis was done to discriminate between field-collected samples of Alestes sp. The LLS, AFR, and LDFL (Longest of Dorsal Fin Lings) were found to be the main characters that discriminate between the four populations.\u0000 \u0000 \u0000 \u0000 The first function showed that they were significantly different. This discrimination was a complete one since 98.1% of original grouped specimens and 97.8% of the cross-validated ones were correctly classified. The scatter plot of Discriminant scores from the three functions showed some relatedness between Alestes baremoze and Alestes dentex.\u0000 16S ribosomal RNA primers have been used to identify the species at the molecular level. All species have shown a characteristic band (680 bp) indicating successful amplification. Five RAPD primers have been used to investigate the Alestes species. Similar and dissimilar DNA bands indicate the evolutionary connections and genetic spacing, respectively. The derived dendrograms based on morphometric measurements and meristic counts were closer to that derived from the RAPD PCR results.\u0000 \u0000 \u0000 \u0000 The study showed co-existence of four Alestes species in the main River Nile.\u0000","PeriodicalId":22949,"journal":{"name":"The Open Biology Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90337852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

New Record of the Giant Timber Flies (Diptera: Pantophathalmidae) from Sartenejas Valley, Miranda, Venezuela 委内瑞拉米兰达Sartenejas山谷巨型木蝇新记录(双翅目:木蝇科)

The Open Biology Journal Pub Date : 2019-07-31 DOI: 10.2174/1874196701907010021

H. Carvajal-Chitty, Aivlé C. Cabrera G.

引用次数: 1

Gompertz’ Hazard Law as a Network Principle of Aging Gompertz的危害定律作为一种网络老化原理

The Open Biology Journal Pub Date : 2019-05-31 DOI: 10.2174/1874196701907010014

J. Korf, A. A. Sas

{"title":"Gompertz’ Hazard Law as a Network Principle of Aging","authors":"J. Korf, A. A. Sas","doi":"10.2174/1874196701907010014","DOIUrl":"https://doi.org/10.2174/1874196701907010014","url":null,"abstract":"\u0000 \u0000 Life-spanning population survivorship curves (the number of survivors versus age) are conventionally regarded as a demographic issue. Most often, the term hazard, the relative mortality per age-interval, is used as a typical survivorship parameter. Population survivorship curves are construed from cross-sectional data (single event per individual; here, mortality).\u0000 \u0000 \u0000 \u0000 We tested (quantitatively) how Gompertz’ law describes the mortality pattern of a wide variety of organisms, some of them fed with lifespan affecting diets. Moreover, we tested (semi-quantitatively) whether Gompertz’ law describes the disintegration of a (biological) small-world network.\u0000 \u0000 \u0000 \u0000 The Gompertz tests, explored in demographic data of humans (male/female) and 4 animal species (mice, honeybees, fruit flies, houseflies), were analyzed with conventional software. The Gompertz law was examined in a small-world network model.\u0000 \u0000 \u0000 \u0000 Gompertz' law applies to all cohorts; thus, with or without exposure to experimental conditions. It describes in all cohorts old-age slowing of mortality. Gompertz’ law is compatible with a gradual and random increase of connections in the network model.\u0000 \u0000 \u0000 \u0000 Old-age deceleration of mortality is a characteristic of many populations. Aging has to be understood as a lifetime increasing of excitatory or, alternatively, of decreasing inhibitory (biological) connections, thereby facilitating pathogenic mechanisms.\u0000","PeriodicalId":22949,"journal":{"name":"The Open Biology Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77923201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Effects of Exercise and Bioprocessed Soybean Meal Diets during Rainbow Trout Rearing 运动和生物加工豆粕饲料对虹鳟鱼养殖的影响

The Open Biology Journal Pub Date : 2019-04-16 DOI: 10.2174/1874196701907010001

J. Voorhees, M. E. Barnes, S. Chipps, Michael L. Brown

{"title":"Effects of Exercise and Bioprocessed Soybean Meal Diets during Rainbow Trout Rearing","authors":"J. Voorhees, M. E. Barnes, S. Chipps, Michael L. Brown","doi":"10.2174/1874196701907010001","DOIUrl":"https://doi.org/10.2174/1874196701907010001","url":null,"abstract":"\u0000 \u0000 Alternative protein sources to fishmeal in fish feeds are needed.\u0000 \u0000 \u0000 \u0000 Evaluate rearing performance of adult rainbow trout (Oncorhynchus mykiss) (initial weight 139.0 ±1.5 g, length 232.9 ± 0.8 mm, mean ± SE) fed one of the two isonitrogenous and isocaloric diets (46% protein, 16% lipid) and reared at one of the two levels of exercise (water velocities of either 3.6 cm/s or 33.2 cm/s).\u0000 \u0000 \u0000 \u0000 Protein in the control diet was based on fishmeal. In the experimental diet, bioprocessed soybean meal replaced approximately 60% of the fishmeal. Fish were fed by hand once-per-day to near satiation, and the food was increased daily. The experiment lasted 90-days.\u0000 \u0000 \u0000 \u0000 There were no significant differences in gain, percent gain, or specific growth rate between the dietary treatments. However, the amount of food fed and feed conversion ratio was significantly lower in the 60% bioprocessed soybean meal diet. Intestinal morphology, relative fin length, splenosomatic index, hepatosomatic index, and viscerosomatic index were not significantly different in the trout fed either diet. Fish reared at 3.6 cm/s had a significantly lower feed conversion ratio (1.02 ± 0.02) than fish reared at 33.2 cm/s (1.13 ± 0.02). However, there were no significant differences in gain, percent gain, specific growth rate, or percentage mortality in fish reared with or without exercise. No significant interactions were observed between diet and exercise (higher water velocity).\u0000 \u0000 \u0000 \u0000 Based on these results, at least 60% of the fishmeal in adult rainbow trout diets can be replaced by bioprocessed soybean meal, even if higher water velocities are used to exercise the fish.\u0000","PeriodicalId":22949,"journal":{"name":"The Open Biology Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73268322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

A Basis of the Crenation of Erythrocyte Ghosts by Electrolytes 电解质产生红细胞鬼影的基础

The Open Biology Journal Pub Date : 2013-11-29 DOI: 10.2174/1874196701306010014

P. Wong

{"title":"A Basis of the Crenation of Erythrocyte Ghosts by Electrolytes","authors":"P. Wong","doi":"10.2174/1874196701306010014","DOIUrl":"https://doi.org/10.2174/1874196701306010014","url":null,"abstract":"Erythrocyte ghosts isolated in hemolytic hypotonic buffers, pH 7.0-8.0, 0-4 o C were previously observed to be crenated by electrolytes. This shape transformation, which occurred rapidly and reversibly, was attributed to electrostatic interactions of cations with flexible filamentous anionic spectrin, the major protein component of the skeleton and/or anionic phospholipids, since divalent cationic salts crenated at concentrations substantially lower than those of monovalent cationic salts and that crenation appeared unrelated to the anion species. However, crenation by electrolytes was markedly influenced by ionic conditions and temperature. A mechanism of the erythrocyte shape control has been previously suggested in which band 3 (AE1), exchanging the monovalent anions Cl - and HCO 3 - and linked to spectrin, plays a pivotal role. Briefly, the alternative recruitment of its inward-facing (band 3 i ) and outward-facing (band 3 o ) conformations contract and relax the skeleton, thereby promoting echinocytosis and stomatocytosis, respectively. Band 3 transports also other anions, including endogenous inorganic phosphate, but at a slow rate. This mechanism would explain the above observations and would lead to some inferences, one of which is a Cl - -dependent crenation by Mg 2+ and Ca 2+ , suggesting that they specifically bind on sites on spectrin.","PeriodicalId":22949,"journal":{"name":"The Open Biology Journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2013-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83442712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2