The LancetPub Date : 2025-10-10DOI: 10.1016/s0140-6736(25)02021-5
Ole Petter Ottersen, Omnia El Omrani, Roland Göhde, Detlev Ganten
{"title":"The Virchow Prize: honouring progress towards health for all","authors":"Ole Petter Ottersen, Omnia El Omrani, Roland Göhde, Detlev Ganten","doi":"10.1016/s0140-6736(25)02021-5","DOIUrl":"https://doi.org/10.1016/s0140-6736(25)02021-5","url":null,"abstract":"No Abstract","PeriodicalId":22898,"journal":{"name":"The Lancet","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145255260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The LancetPub Date : 2025-10-10DOI: 10.1016/s0140-6736(25)01920-8
Quarraisha Abdool Karim, Jivanka Mohan, Zulfiqar A Bhutta
{"title":"Advancing women, maternal, newborn, and child health equity","authors":"Quarraisha Abdool Karim, Jivanka Mohan, Zulfiqar A Bhutta","doi":"10.1016/s0140-6736(25)01920-8","DOIUrl":"https://doi.org/10.1016/s0140-6736(25)01920-8","url":null,"abstract":"<h2>Section snippets</h2><section><section><section><h2>Quarraisha Abdool Karim and Jivanka Mohan</h2>Over the past three decades, through science, activism, and global solidarity, unprecedented progress has been made in the global response to HIV. Antiretroviral therapy has transformed AIDS from an inevitably fatal condition to one that is chronic and manageable and the use of antiretrovirals by mothers living with HIV has reduced transmission rates to infants to less than 2%. Notwithstanding, in 2024 an estimated 1·3 million new HIV infections occurred, mostly in adolescent girls and young</section></section></section><section><section><section><h2>Zulfiqar A Bhutta</h2>To many in my generation of medical students from the early 1970s, the concept of global health and equity did not exist. The reality of health disparities and poor outcomes among women and children stared at us in everyday practice but was not reflected in any solid epidemiology or global statistics. In my case, this early exposure to the abysmal state of maternal and newborn health sparked a deep interest in the nascent discipline of newborn medicine, eventually resulting in a decision to</section></section></section><section><section><h2>Declaration of interests</h2>ZAB is the Robert Harding Chair in Global Child Health and Policy at the Hospital for Sick Children, Toronto and is a Senior Fellow in Climate and Child Health, Lawson Centre for Child Nutrition, University of Toronto, Canada. ZAB reports that the Virchow Foundation will support travel in part to attend and deliver this lecture. QAK reports a patent with Gilead for Tenofovir gel for the pending prevention of HSV-2 infection and that the Virchow Foundation has contributed to travel and</section></section>","PeriodicalId":22898,"journal":{"name":"The Lancet","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145255262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The LancetPub Date : 2025-10-10DOI: 10.1016/s0140-6736(25)02068-9
{"title":"Department of Error","authors":"","doi":"10.1016/s0140-6736(25)02068-9","DOIUrl":"https://doi.org/10.1016/s0140-6736(25)02068-9","url":null,"abstract":"<em>Vitale A, Abu Hilal M, Gumbs AA, Umberto Cillo, Isabella Frigerio. Gaza's healthocide: medical societies must not stay silent.</em> Lancet <em>2025; <strong>406:</strong> 1467–68</em>—In this Correspondence, Amir Szold has requested to be removed as an author. This correction has been made to the online version as of Oct 10, 2025.","PeriodicalId":22898,"journal":{"name":"The Lancet","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145255263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The LancetPub Date : 2025-10-09DOI: 10.1016/s0140-6736(25)02062-8
{"title":"Reclaiming care in the age of AI","authors":"","doi":"10.1016/s0140-6736(25)02062-8","DOIUrl":"https://doi.org/10.1016/s0140-6736(25)02062-8","url":null,"abstract":"No Abstract","PeriodicalId":22898,"journal":{"name":"The Lancet","volume":"105 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145255268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The LancetPub Date : 2025-10-09DOI: 10.1016/s0140-6736(25)02059-8
Andrew Green
{"title":"US aid cuts: a new era of HIV care in Malawi","authors":"Andrew Green","doi":"10.1016/s0140-6736(25)02059-8","DOIUrl":"https://doi.org/10.1016/s0140-6736(25)02059-8","url":null,"abstract":"No Abstract","PeriodicalId":22898,"journal":{"name":"The Lancet","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145255274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The LancetPub Date : 2025-10-09DOI: 10.1016/s0140-6736(25)01539-9
Richard J Lilford, Samuel I Watson, Peter J Chilton
{"title":"Rethinking induction of labour for LGA fetuses: the Big Baby trial","authors":"Richard J Lilford, Samuel I Watson, Peter J Chilton","doi":"10.1016/s0140-6736(25)01539-9","DOIUrl":"https://doi.org/10.1016/s0140-6736(25)01539-9","url":null,"abstract":"No Abstract","PeriodicalId":22898,"journal":{"name":"The Lancet","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145255278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The LancetPub Date : 2025-10-09DOI: 10.1016/s0140-6736(25)01846-x
Linda-Gail Bekker, Dvora Joseph Davey, Friday Saidi
{"title":"Two for two: lenacapavir during pregnancy and lactation","authors":"Linda-Gail Bekker, Dvora Joseph Davey, Friday Saidi","doi":"10.1016/s0140-6736(25)01846-x","DOIUrl":"https://doi.org/10.1016/s0140-6736(25)01846-x","url":null,"abstract":"No Abstract","PeriodicalId":22898,"journal":{"name":"The Lancet","volume":"37 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145255275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The LancetPub Date : 2025-10-09DOI: 10.1016/s0140-6736(25)02057-4
{"title":"Department of Error","authors":"","doi":"10.1016/s0140-6736(25)02057-4","DOIUrl":"https://doi.org/10.1016/s0140-6736(25)02057-4","url":null,"abstract":"<em>Luk A, Wild SH, Jones S, et al. Early-onset type 2 diabetes: the next major diabetes transition.</em> Lancet <em>2025; <strong>405:</strong> 2313–26</em>—In this Series paper, in the final section of the panel, the reference number for the statement, “In Japan and South Korea, type 2 incidence exceeded type 1 diabetes across the full age range in males” was changed to 44. In the third paragraph of the Defining early-onset type 2 diabetes section, reference 35 for the statement, “Therefore, lower age cutoffs might be needed to adequately define early-onset type 2 diabetes in some populations at high risk” was removed. In the fifth paragraph of the Obesity as the key risk factor for early-onset type 2 diabetes section, the references for the statement, “The rate of weight gain and duration of exposure to excess weight also appear to be a similarly potent risk factor (figure 3B)” were changed to 35,53,78,79. In the next sentence, the reference was changed from 83 to 78. In the penultimate paragraph of the same section, the reference number for the statement, “…so it remains unclear whether these associations are stronger in young versus older women” was changed to 78. In the following paragraph, the reference numbers for the statement, “…which have led to lower BMI-based thresholds for diabetes risk in Asian populations” were changed to 84,86–89. John McCaffrey's degree was incorrect. These corrections have been made to the online version as of Oct 9, 2025.","PeriodicalId":22898,"journal":{"name":"The Lancet","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145255280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The LancetPub Date : 2025-10-09DOI: 10.1016/s0140-6736(25)01537-5
Anne N Blaauwgeers, Benjamin Y Gravesteijn, Joost Velzel
{"title":"Rethinking induction of labour for LGA fetuses: the Big Baby trial","authors":"Anne N Blaauwgeers, Benjamin Y Gravesteijn, Joost Velzel","doi":"10.1016/s0140-6736(25)01537-5","DOIUrl":"https://doi.org/10.1016/s0140-6736(25)01537-5","url":null,"abstract":"No Abstract","PeriodicalId":22898,"journal":{"name":"The Lancet","volume":"90 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145255281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The LancetPub Date : 2025-10-09DOI: 10.1016/s0140-6736(25)01496-5
Jürgen Rehm, Sawitri Assanangkornchai, Christian S Hendershot, Ari Franklin, Maria Neufeld, Ahmed S Hassan, Kevin D Shield
{"title":"Alcohol use disorders","authors":"Jürgen Rehm, Sawitri Assanangkornchai, Christian S Hendershot, Ari Franklin, Maria Neufeld, Ahmed S Hassan, Kevin D Shield","doi":"10.1016/s0140-6736(25)01496-5","DOIUrl":"https://doi.org/10.1016/s0140-6736(25)01496-5","url":null,"abstract":"Alcohol use disorders consist of conditions characterised by compulsive heavy alcohol use and loss of control over alcohol intake. Alcohol use disorders are some of the most prevalent mental disorders globally, with higher prevalence in high-income countries and lower prevalence in low-income countries. The recent COVID-19 pandemic was associated with an increase in fully alcohol-attributable mortality, in part triggered by alcohol-specific interactions with stress. Despite their high prevalence, alcohol use disorders remain undertreated, even though there are scientifically established and cost-effective psychosocial, community, and pharmacological interventions available. In addition, promising new treatment modalities have been developed and are currently being tested. The two main barriers to better access to evidence-based alcohol use disorder treatment are low availability, due to the absence of government or public funding for such treatment, and stigma. The first barrier could be overcome by increasing alcohol excise taxation, which currently falls considerably short of covering the social costs of alcohol use. In addition to generating revenues, increasing excise taxation could reduce health-care costs by reducing hospitalisations for all alcohol-attributable conditions, including alcohol use disorders. Overall, integrated alcohol control policies could improve the prevention of alcohol use disorders, improve access to treatment, and reduce stigma.","PeriodicalId":22898,"journal":{"name":"The Lancet","volume":"23 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145255266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}