The Journal of Qazvin University of Medical Sciences最新文献_第2页

A 10-Zear Epidemiological Study of Human Cystic Echinococcosis in Qazvin Province, Iran 伊朗加兹温省人类囊性包虫病10年流行病学调查

The Journal of Qazvin University of Medical Sciences Pub Date : 2021-09-01 DOI: 10.32598/jqums.25.3.3

Amin Yazdani, Behnaz Familsatarian, H. Bagheri, A. Mohammadzadeh, Z. Hosseinkhani

{"title":"A 10-Zear Epidemiological Study of Human Cystic Echinococcosis in Qazvin Province, Iran","authors":"Amin Yazdani, Behnaz Familsatarian, H. Bagheri, A. Mohammadzadeh, Z. Hosseinkhani","doi":"10.32598/jqums.25.3.3","DOIUrl":"https://doi.org/10.32598/jqums.25.3.3","url":null,"abstract":"Background: Cystic echinococcosis (CE) is a parasitic infection with significant health problems and economic burden in most of developing countries. The current study aims to investigate the 10-year prevalence of human CE and the demographic and clinical characteristics of operated patients in Qazvin province, Iran. Methods: In this cross-sectional study, the medical records of CE patients who had undergone surgery in two hospitals of Qazvin Province from 2009 to 2019 were studied. Findings: There was 203 CE cases in ten years, corresponding to a surgical incidence rate of 1.49 in 100,000 people. Of these, 99(48.8%) were male, and 104 (51.2%) were female. Patients’ age ranged from 8 to 86 years, with a mean age of 43±19.16 years. A significantly higher CE incidence was reported in patients aged 20-40 years. The majority of patients were housekeeper (48.8%), and the CE was diagnosed in almost all patients by imaging techniques. Involved organs were liver (n=119, 58.6%) and lungs (n=64, 31.5%), and their concurrent involvement was 4.5% (n=9). The highest CE incidence was recorded in 2015 (n=35, 17.2%). Affected organ and number of cysts had significant association with the CE recurrence in operated patients. Conclusion: The CE has had a uneven incidence trend in Qazvin Province during 2009-2019. A further epidemiological study is recommended to evaluate more risk factors of CE for its control in this area.","PeriodicalId":22748,"journal":{"name":"The Journal of Qazvin University of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41865991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mortality Risk Factors Among Hospitalized Older Patients With COVID-19 住院老年COVID-19患者的死亡危险因素

The Journal of Qazvin University of Medical Sciences Pub Date : 2021-09-01 DOI: 10.32598/jqums.25.3.6

Fariba Abdollahi, Mostafa Keshavarz Rad, Miaad Mirzapour, Mahdi Rajabi Yekta, Alireza Alimohammadiha, M. Nouri, S. Motalebi

{"title":"Mortality Risk Factors Among Hospitalized Older Patients With COVID-19","authors":"Fariba Abdollahi, Mostafa Keshavarz Rad, Miaad Mirzapour, Mahdi Rajabi Yekta, Alireza Alimohammadiha, M. Nouri, S. Motalebi","doi":"10.32598/jqums.25.3.6","DOIUrl":"https://doi.org/10.32598/jqums.25.3.6","url":null,"abstract":"Background: The Coronavirus disease 2019 (COVID-19) is an infectious disease with a high mortality rate among older people. Objective: The current study aims to investigate the death rate and related factors among hospitalized older patients with COVID-19 in Qazvin, Iran. Methods: In this descriptive and cross-sectional study, 430 older inpatients with COVID-19 (Mean±SD age: 72.83±8.81) admitted to two hospitals in Qazvin, Iran were randomly selected. Their information was extracted from their electronic health records. Independent t-test, chi-square test, and multivariate logistic regression analysis were used for the data analysis. Findings: Hypertension (n=234, 54.4%), diabetes mellitus (n=148, 34.4%), and cardiovascular diseases (n=127, 29.4%) were the most prevalent comorbidities. Dyspnea (n=300, 69.8%), cough (n=232, 54.0%), fever (n=186, 43.3%), and general malaise (n=168, 39.1%) were the most frequent clinical symptoms. There was in-hospital mortality in 108 (25.1%) older inpatients. Multivariate regression results showed that the risk of in-hospital death was significantly related to the inpatients’ age (OR=1.037, 95%CI=1.007-1.068), white blood cell count (OR=1.187, 95%CI=1.114-1.264), hemoglobin level (OR=0.812, 95%CI=0.720-0.914), platelet count (OR=0.993, 95%CI=0.989-0.996), and oxygen saturation level (OR=0.950, 95%CI=0.967-0.932) at the time of admission. Conclusion: Older age, white blood cell count, hemoglobin level, oxygen saturation level, and platelet count are predictors of death among older inpatients with COVID-19. Identification of these risk factors can assist the healthcare providers for timely intervention for the prevention of death.","PeriodicalId":22748,"journal":{"name":"The Journal of Qazvin University of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45426042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Difference in Immunoglobulin G Levels Between Outpatients and Inpatients With COVID-19 新型冠状病毒肺炎门诊与住院患者免疫球蛋白G水平的差异

The Journal of Qazvin University of Medical Sciences Pub Date : 2021-09-01 DOI: 10.32598//jqums.25.3.4

P. Madani, M. Mirzadeh, S. Rostamian

{"title":"The Difference in Immunoglobulin G Levels Between Outpatients and Inpatients With COVID-19","authors":"P. Madani, M. Mirzadeh, S. Rostamian","doi":"10.32598//jqums.25.3.4","DOIUrl":"https://doi.org/10.32598//jqums.25.3.4","url":null,"abstract":"Background: Coronavirus disease 2019 (COVID-19) has rapidly become a pandemic since it was first reported in late December 2019. Serological reports are of great value to medical specialists in developing health policies. The detection of Immunoglobulin G (IgG) level in COVID-19 patients can specify a preclinical infection or previous exposure to the virus. Objective: This study aims to assess the IgG rate in patients with COVID-19. Methods: This is a cross-sectional study on 172 patients with confirmed COVID-19 (having positive PCR test) in Qazvin, Iran in 2020, including 86 inpatients and 86 outpatients. In order to measure the IgG levels, the serum samples were collected 3-5 weeks after onset of their clinical symptoms. Data were statistically analyzed in SPSS software v. 20, considering the significance level of P<0.05. Results: Of 172 patients, 81(94.2%) inpatients and 74(86%) outpatients tested positive for IgG, while 5(5.8%) inpatients and 10(11.6%) outpatients tested negative for IgG. The mean IgG level in inpatients was significantly higher than in outpatients (P<0.001) 3-5 weeks after a positive PCR test. Conclusion: The amounts of IgG in the sera of COVID-19 patients 3-5 weeks after the onset of symptoms can help health care authorities develop policies and control strategies by determining the burden of disease, monitoring the spread of disease, and estimating the epidemiological factors.","PeriodicalId":22748,"journal":{"name":"The Journal of Qazvin University of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69704885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hyponatremia at Admission in Hospitalized Patients With COVID-19: Risk Factors and Impact on Prognosis 新冠肺炎住院患者入院时低钠血症的危险因素及其对预后的影响

The Journal of Qazvin University of Medical Sciences Pub Date : 2021-09-01 DOI: 10.32598/jqums.25.3.2

Negar Sheikhdavoodi, M. Gheraati, S. Hashemipour, Milad Badri, Nafiseh Rastgoo, A. Shokri, Sohrab Esmaielzade, M. Karbasi, K. Esmaeilzadeh

{"title":"Hyponatremia at Admission in Hospitalized Patients With COVID-19: Risk Factors and Impact on Prognosis","authors":"Negar Sheikhdavoodi, M. Gheraati, S. Hashemipour, Milad Badri, Nafiseh Rastgoo, A. Shokri, Sohrab Esmaielzade, M. Karbasi, K. Esmaeilzadeh","doi":"10.32598/jqums.25.3.2","DOIUrl":"https://doi.org/10.32598/jqums.25.3.2","url":null,"abstract":"Background: Electrolyte disorders, particularly hyponatremia, have been reported in a considerable number of patients with Coronavirus Disease 2019 (COVID-19). Objective: The current study aims to evaluate the risk factors, symptoms, and prognosis of hyponatremia in hospitalized patients with COVID-19. Methods: In this retrospective cohort study, 467 patients with COVID-19 were divided into 4 groups based on the sodium level at the time of admission: normal, mild hyponatremia, moderate hyponatremia, and severe hyponatremia. Symptoms, laboratory findings, and prognosis were compared among these groups. The risk factors for the occurrence of moderate/severe hyponatremia and the association of hyponatremia with in-hospital mortality were investigated using logistic regression analysis. Findings: Hyponatremia was diagnosed in 60% of the patients. The prevalence of mild, moderate, and severe hyponatremia was 80.7%, 15.1%, and 4.2%, respectively. The severity of the clinical symptoms and level of hypoxia showed no significant difference between the groups. White blood cells count was significantly higher and lymphocyte percentage was significantly lower in hyponatremia groups compared to the normal group. The history of chronic kidney disease was an independent risk factor for the moderate/severe hyponatremia (Adjusted OR=5.11, 95%CI: 1.72-15.2, P=0.003). After adjustment of different risk factors, moderate/severe hyponatremia remained a significant independent risk factor for in-hospital mortality (OR=2.58, 95%CI: 1.13-5.88, P=0.024). Conclusion: Hyponatremia is prevalent in COVID-19 patients. However, it is not definitely associated with severity of COVID-19 at the time of admission. Moderate/severe hyponatremia is associated with higher in-hospital mortality rate despite the similarity of disease severity between the sodium groups.","PeriodicalId":22748,"journal":{"name":"The Journal of Qazvin University of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41927578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship Between Medication Adherence and Ankle-Brachial Index Value in Patients With Hypertention 高血压患者用药依从性与踝肱指数的关系

The Journal of Qazvin University of Medical Sciences Pub Date : 2021-09-01 DOI: 10.32598/jqums.25.3.8

Simin Heidari, L. Yekefallah, Azadeh Jalalpor, M. Ranjbaran, H. Talakoob

{"title":"Relationship Between Medication Adherence and Ankle-Brachial Index Value in Patients With Hypertention","authors":"Simin Heidari, L. Yekefallah, Azadeh Jalalpor, M. Ranjbaran, H. Talakoob","doi":"10.32598/jqums.25.3.8","DOIUrl":"https://doi.org/10.32598/jqums.25.3.8","url":null,"abstract":"Background: Hypertension is one of the leading causes of death and physical disabilities. The ankle-brachial index (ABI) is one of the useful indicators of blood pressure with the ability to show the risk of peripheral artery disease. This study aims to investigate the relationship between medication adherence and the ABI lavue in patients with hypertension. Methods: In this descriptive cross-sectional study, 250 patients with hypertension referred to medical health centers in Karaj, Iran were enrolled using a convenience sampling method. To collect data, a demographic form and the 8-item morisky medication adherence scale (MMAS-8) were used. Also, the ABI was measured manually using an acoustic Doppler probe. Data were analyzed in SPSS software, v. 25. Findings: The Mean±SD of the right and left ABI were 1.055±0.134 and 1.036±0.113, respectively. The Mean±SD of MMAS-8 score was 5.88±1.74. It was found that 127 patients (50.8%) had low adherence level, 68 (27.2%) had moderate adherence level, and only 55 (22%) had high adherence level. There was a positive significant correlation between patients’ medication adherence and the ABI value. Moreover, a statistically significant difference was observed in the mean scores of the ABI in patients with three different levels of medication adherence. Conclusion: The medication adherence is poor among hypertensive patients in Karaj. It is related to the ABI such that with the decrease of medication adherence, the ABI value decreases. Therefore, adherence to medication regimen in patients with hypertension can be effective in preventing arterial complications.","PeriodicalId":22748,"journal":{"name":"The Journal of Qazvin University of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44194234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of Two MMP-8 Gene Polymorphisms With Recurrent Pregnancy Loss in Iranian Women 两种MMP-8基因多态性与伊朗妇女复发性妊娠丢失的关系

The Journal of Qazvin University of Medical Sciences Pub Date : 2021-09-01 DOI: 10.32598/jqums.25.3.5

R. Najafipour, Zahar Rashvand, Khadijeh Taherkhani, Solmaz Chamanara, S. Abotorabi, S. Moghbelinejad

引用次数: 0

The Effectiveness of Pilates Training and Vitamin D Intake on the hs-CRP and TSH in Overweight Men 普拉提训练和维生素D摄入对超重男性hs-CRP和TSH的影响

The Journal of Qazvin University of Medical Sciences Pub Date : 2021-04-01 DOI: 10.32598/jqums.25.1.8

Fatemeh Ebrahemi Rokni, M. Habibian, Saqqa Farajtabar Behrestaq

{"title":"The Effectiveness of Pilates Training and Vitamin D Intake on the hs-CRP and TSH in Overweight Men","authors":"Fatemeh Ebrahemi Rokni, M. Habibian, Saqqa Farajtabar Behrestaq","doi":"10.32598/jqums.25.1.8","DOIUrl":"https://doi.org/10.32598/jqums.25.1.8","url":null,"abstract":"Background: Vitamin D deficiency is known as a risk factor for various diseases and plays an important role in regulating systemic inflammation and thyroid function. Objective: The study was done to survey the effectiveness of Pilates training and vitamin D intake on serum high-sensitivity C-reactive protein (hs-CRP) and Thyroid-Stimulating Hormone (TSH) levels in overweight men. Methods: This clinical trial was conducted on 50 overweight men aged 45-55 years. Subjects were selected through available sampling and randomly assigned to the Pilates training, Pilates training with vitamin D, vitamin D, and control groups. The Pilates training was performed for eight weeks with the intensity of 50%-75% of reserve heart rate in 3 sessions/week. The supplement groups received 50000IU vitamin D weekly. The levels of hs-CRP and TSH were measured at first and eighth weeks after interventions. The data were analyzed by paired t-test and one-way ANOVA (p˂0.05). Findings: The results showed that 60% and 40% of the subjects had a vitamin D deficiency and insufficiency, respectively. Also, eight weeks of Pilates training, vitamin D intake, and the combined intervention resulted in a significant decrease in hs-CRP and TSH levels (p<0.05). Also, the combined intervention was associated with a stronger effect on the reduction of these factors compared with two other interventions (p˂0.05). Conclusion: It seems that abnormal levels of vitamin D are common in overweight men and vitamin D intake, Pilates training, and the combination can improve thyroid function and systemic inflammation in overweight men with abnormal vitamin D status. However, the combined intervention is associated with stronger effects.","PeriodicalId":22748,"journal":{"name":"The Journal of Qazvin University of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42283566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

The Effects of Prenatal Norharman Exposure on Seizure Severity in Rats Norharman产前暴露对大鼠癫痫发作严重程度的影响

The Journal of Qazvin University of Medical Sciences Pub Date : 2021-04-01 DOI: 10.32598/jqums.25.1.3

M. Esmaeili, M. Sofiabadi, A. Afshar

引用次数: 0

The Effects of Pentoxifylline on Memory in Male Rats Treated with Zinc Oxide NPs 己酮茶碱对氧化锌NPs处理的雄性大鼠记忆的影响

The Journal of Qazvin University of Medical Sciences Pub Date : 2021-01-01 DOI: 10.32598/jqums.25.1.1

N. Darbandi, Zeynab Vasheghani Farahani, H. Momeni

{"title":"The Effects of Pentoxifylline on Memory in Male Rats Treated with Zinc Oxide NPs","authors":"N. Darbandi, Zeynab Vasheghani Farahani, H. Momeni","doi":"10.32598/jqums.25.1.1","DOIUrl":"https://doi.org/10.32598/jqums.25.1.1","url":null,"abstract":"Background: Zinc oxide Nanoparticles (NPs) present irreversible effects on the nervous system, memory, and learning. Objective: The current study aimed to investigate the effects of pentoxifylline on memory impairments, CA1 hippocampal pyramidal cells, and blood serum antioxidant enzymes in male rats treated with zinc oxide NPs. Methods: Male Wistar rats were divided into the control, zinc oxide NPs (1.25 mg/kg), pentoxifylline (50 mg/kg), and pentoxifylline with zinc oxide NPs groups. In all study groups, saline, zinc oxide NPs, and pentoxifylline were intraperitoneally injected 30 minutes before training. In the co-treatment group, pentoxifylline was injected one hour before injecting Zno NPs. After performing the behavioral test, the tested animals’ brains were fixed and the number of healthy neurons in the CA1 region of the hippocampus was counted. In all research groups, malondialdehyde levels, total antioxidant power, superoxide dismutase levels, and glutathione peroxidase in blood serum were measured. Results: Zinc oxide nanoparticles decreased memory and the number of healthy neurons in the CA1 region of the hippocampus and increased oxidative stress in blood serum, compared to the controls. In the co-treatment group, using pentoxifylline improved the above-mentioned factors and reached the level of the control group. Pentoxifylline alone presented no significant effect on the aforementioned characteristics, compared to the control group. Conclusion: ZnO NPs may decrease memory retrieval and cause cell death in the pyramidal neurons of the CA1 region of the hippocampus by increasing oxidative stress. Pentoxifylline, as a potent antioxidant, can prevent the harmful effects of ZnO NPs.","PeriodicalId":22748,"journal":{"name":"The Journal of Qazvin University of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69708274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Barriers to Receiving Tissue Plasminogen Activator in Patients with Ischemic Stroke 缺血性脑卒中患者接受组织纤溶酶原激活剂的障碍

The Journal of Qazvin University of Medical Sciences Pub Date : 2021-01-01 DOI: 10.32598/jqums.25.1.2

M. Mirzadeh, H. Mozhdehipanah, A. Emami, N. Motamed

{"title":"Barriers to Receiving Tissue Plasminogen Activator in Patients with Ischemic Stroke","authors":"M. Mirzadeh, H. Mozhdehipanah, A. Emami, N. Motamed","doi":"10.32598/jqums.25.1.2","DOIUrl":"https://doi.org/10.32598/jqums.25.1.2","url":null,"abstract":"Background: Cerebrovascular diseases are the second common cause of mortality worldwide. The onset of reperfusion in the first 3-4.5 hours is a predictive factor of treatment. Objective: The present study investigated barriers to receiving tissue plasminogen activator in patients with ischemic stroke. Methods: This cross-sectional study examined 191 patients with first-ever stroke referring to the emergency department of the Persian Gulf Martyrs Hospital of Bushehr City, Iran, in 2016. One checklist was completed which included demographic data, history of diseases, knowledge of stroke symptoms, and intervals regarding the onset of symptoms to informing emergency, informing emergency on arrival at the emergency department of the hospital, and making the diagnosis for the patients. The obtained data were analyzed in SPSS v. 19. Results: Mean±SD age of the patients was 65.92±12.48 years. The majority of patients under investigation (55.5%) were female, 63.4% were married, 56% were illiterate and 72.3% resided in other districts of Bushehr province. Mean duration between onset of symptoms and arrival at emergency department, onset of symptoms and call the emergency service, time of arrival at emergency department to perform brain Computer Tomography (CT) scan and also to be counseled by a neurologist were 699.66, 195.51, 45.11 and 423.62 minutes, respectively. Finally 14.6 percent of patients were qualified to be treated with tPA. Conclusion: The main barrier to timely therapy is a delay in golden time. Therefore, public education to promote public awareness could be of great benefit in reducing the referral delay time.","PeriodicalId":22748,"journal":{"name":"The Journal of Qazvin University of Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69708286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0