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International Journal of Pharmacy Research & Technology最新文献

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Formulation, Evaluation and Optimization of Transdermal Drug Delivery System of Methotrexate Using Different Ratio of Eudragit RLPO / RSPO 不同比例灯芯草RLPO / RSPO甲氨蝶呤透皮给药体系的制备、评价及优化
International Journal of Pharmacy Research & Technology Pub Date : 2019-01-01 DOI: 10.31838/ijprt/02.02.11
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引用次数: 4
Development and Validation of Stability Indicating HPTLC Method for Estimation of Acebrophylline in Their Dosage Form hplc法测定乙酰茶碱剂型的稳定性及验证
International Journal of Pharmacy Research & Technology Pub Date : 2019-01-01 DOI: 10.31838/ijprt/03.01.01
{"title":"Development and Validation of Stability Indicating HPTLC Method for Estimation of Acebrophylline in Their Dosage Form","authors":"","doi":"10.31838/ijprt/03.01.01","DOIUrl":"https://doi.org/10.31838/ijprt/03.01.01","url":null,"abstract":"","PeriodicalId":225304,"journal":{"name":"International Journal of Pharmacy Research & Technology","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114081488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
"Antiurolithiatic Activity Studies of Momordica charantia Linn. Fruits " 莫莫迪亚·查兰蒂亚·林的抗尿溶解活性研究。Fruits”
International Journal of Pharmacy Research & Technology Pub Date : 2019-01-01 DOI: 10.31838/ijprt/01.01.02
B. Shah, Khodidas D. Raiyani, D. C. Modi
{"title":"\"Antiurolithiatic Activity Studies of Momordica charantia Linn. Fruits \"","authors":"B. Shah, Khodidas D. Raiyani, D. C. Modi","doi":"10.31838/ijprt/01.01.02","DOIUrl":"https://doi.org/10.31838/ijprt/01.01.02","url":null,"abstract":"In the indigenous system of medicine, the fruits of Momordica charantia Linn. (Family- Cucurbitaceae) are reported to be useful in the treatment of urinary stones. Hence, in the present study the fruits of Momordica charantia Linn. have been selected for their antiurolithiatic activity on experimentally induced urolithiatic rats. Antiurolithiatic activity of fruit extract of M. charantia Linn. was carried out on ethylene glycol (0.75% v/v) induced urolithiasis in rats. Treatment with Aqueous Extract (200mg/kg, p.o) and Alcoholic Extract (250mg/kg, p.o) of fruits of M. charantia Linn. significantly lowered (P","PeriodicalId":225304,"journal":{"name":"International Journal of Pharmacy Research & Technology","volume":"15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123032173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 15
An Overview on Gastro Retentive Floating Microspheres 胃保留漂浮微球的研究进展
International Journal of Pharmacy Research & Technology Pub Date : 2019-01-01 DOI: 10.31838/ijprt/02.01.01
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引用次数: 0
Formulation and Evaluation of Pulsatile Drug Delivery System of Venlafaxine HCL 盐酸文拉法辛脉动给药系统的研制与评价
International Journal of Pharmacy Research & Technology Pub Date : 2019-01-01 DOI: 10.31838/ijprt/02.01.10
{"title":"Formulation and Evaluation of Pulsatile Drug Delivery System of Venlafaxine HCL","authors":"","doi":"10.31838/ijprt/02.01.10","DOIUrl":"https://doi.org/10.31838/ijprt/02.01.10","url":null,"abstract":"","PeriodicalId":225304,"journal":{"name":"International Journal of Pharmacy Research & Technology","volume":"144 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116427701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Simultaneous Separation of Five Fluoroquinolones - Norfloxacin, Moxifloxacin, Enrofloxacin, Sparfloxacin and Prulifloxacin Using an Isocratic HPLC: Application to Determination of Norfloxacin in Pharmaceutical Formulations 五种氟喹诺酮类药物-诺氟沙星、莫西沙星、恩诺沙星、斯帕沙星和普卢利沙星的同时分离——在制剂中诺氟沙星含量测定中的应用
International Journal of Pharmacy Research & Technology Pub Date : 2019-01-01 DOI: 10.31838/ijprt/03.02.04
{"title":"Simultaneous Separation of Five Fluoroquinolones - Norfloxacin, Moxifloxacin, Enrofloxacin, Sparfloxacin and Prulifloxacin Using an Isocratic HPLC: Application to Determination of Norfloxacin in Pharmaceutical Formulations","authors":"","doi":"10.31838/ijprt/03.02.04","DOIUrl":"https://doi.org/10.31838/ijprt/03.02.04","url":null,"abstract":"","PeriodicalId":225304,"journal":{"name":"International Journal of Pharmacy Research & Technology","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121339517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
An Understanding of Information Literacy and Technology in Community Health 社区卫生中信息素养与技术的认识
International Journal of Pharmacy Research & Technology Pub Date : 2019-01-01 DOI: 10.31838/ijprt/09.01.07
{"title":"An Understanding of Information Literacy and Technology in Community Health","authors":"","doi":"10.31838/ijprt/09.01.07","DOIUrl":"https://doi.org/10.31838/ijprt/09.01.07","url":null,"abstract":"","PeriodicalId":225304,"journal":{"name":"International Journal of Pharmacy Research & Technology","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133875166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
TOXICITY OF NANO-MATERIALS TO ENVIRONMENT AND MANKIND: AN OVERVIEW 纳米材料对环境和人类的毒性研究综述
International Journal of Pharmacy Research & Technology Pub Date : 2019-01-01 DOI: 10.31838/ijprt/07.01.01
{"title":"TOXICITY OF NANO-MATERIALS TO ENVIRONMENT AND MANKIND: AN OVERVIEW","authors":"","doi":"10.31838/ijprt/07.01.01","DOIUrl":"https://doi.org/10.31838/ijprt/07.01.01","url":null,"abstract":"","PeriodicalId":225304,"journal":{"name":"International Journal of Pharmacy Research & Technology","volume":"98 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115721403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Effect of Cryopreservation on Rat Sperm DNA and involvement of elevated Oxidative Stress, Apoptosis – A Review 低温保存对大鼠精子DNA的影响及其与氧化应激、细胞凋亡的关系
International Journal of Pharmacy Research & Technology Pub Date : 2019-01-01 DOI: 10.31838/ijprt/02.01.07
Kamala Katepogu, Divya Kurumala, Thyagaraju Kedam
{"title":"Effect of Cryopreservation on Rat Sperm DNA and involvement of elevated Oxidative Stress, Apoptosis – A Review","authors":"Kamala Katepogu, Divya Kurumala, Thyagaraju Kedam","doi":"10.31838/ijprt/02.01.07","DOIUrl":"https://doi.org/10.31838/ijprt/02.01.07","url":null,"abstract":"Current article explains about the effects of cryopreservation on testicular sperm DNA. Conservation of sperms has several purposes in artificial reproductive technologies (ART), species conservation and clinical medicine. Despite of various advances in cryopreservation methodology, the recovery rate of functional post thawed spermatozoa remains mediocre, with sperm motility being significantly decreased after freezing. Sperm cryopreservation and storage facility currently require liquid nitrogen method for long or short term storage. The combinations of sperm storage involved are temperature, cooling rate, chemical composition of the extender, cryoprotectant concentration, reactive oxygen species (ROS), seminal plasma composition and hygienic control factors that affect the life-span of spermatozoa. The lack of structural integrity to sperm and damage to DNA of sperm shall have a significant negative impact on oocyte fertilization, embryo development rate, and live-birth rate. Hence the research conducted as on today conclude that cryopreservation of testicular spermatozoa may reduce DNA life expectancy; therefore scientists are yet in a position to rectify this troubleshoot for ultimate shell of life of DNA for prolonged periods without damage. This review describes about the effect of oxidative stress and apoptosis as one of the possible mechanisms involved in sperm cryoinjury.","PeriodicalId":225304,"journal":{"name":"International Journal of Pharmacy Research & Technology","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125934459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Formulation, Development and Evaluation of Floating Matrix Tablets of Atorvastatin Calcium 阿托伐他汀钙漂浮基质片的研制与评价
International Journal of Pharmacy Research & Technology Pub Date : 2019-01-01 DOI: 10.31838/ijprt/02.02.12
S. Hardik, K. Tarachand, Yadav Kailash, Bhatt Chintan, Shah Chainesh, R. Vinod
{"title":"Formulation, Development and Evaluation of Floating Matrix Tablets of Atorvastatin Calcium","authors":"S. Hardik, K. Tarachand, Yadav Kailash, Bhatt Chintan, Shah Chainesh, R. Vinod","doi":"10.31838/ijprt/02.02.12","DOIUrl":"https://doi.org/10.31838/ijprt/02.02.12","url":null,"abstract":"S The present study was aimed to prepare a Floating Matrix drug delivery system for the Atorvastatin calcium, andevaluating the various processing parameters including the buoyancy studies and in vitro drug release studies. Fifteen formulations containing varying proportions of polymers like HPMC K100M, HPMC K15M, Ethyl Cellulose and Carbopol 934P and fixed amount of gasgenerating agent such as Sodium bi carbonate and Citric Acid and also MCC in varying concentration as a bulking agent. The tablets were prepared by direct compression technique and the prepared tablets remained buoyant for more than 12 hrs in therelease medium. Batch F15 prepared with different proportions of HPMC K4M, HPMC K100 M and Carbopol 934P showed significant difference in 105 secs, Floating lag time, Total floating time more than 18 hrs and 62.11% releaseupto 12 hrs of the drug which shows extended release may be more than 15 hrs. All theformulations exhibited diffusion dominant drug release. F15 batch also showed stable in means of % Drug Content as it shows no significant change performed as per ICH guidelines for 60 Days.","PeriodicalId":225304,"journal":{"name":"International Journal of Pharmacy Research & Technology","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115309773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
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