发布求助
文献互助 智能选刊 最新文献

International Journal of Pharmacy Research & Technology最新文献

筛选
英文 中文
The Treatment and Epidemiology of Colon Cancer 结肠癌的治疗和流行病学
International Journal of Pharmacy Research & Technology Pub Date : 2019-01-01 DOI: 10.31838/ijprt/09.01.08
{"title":"The Treatment and Epidemiology of Colon Cancer","authors":"","doi":"10.31838/ijprt/09.01.08","DOIUrl":"https://doi.org/10.31838/ijprt/09.01.08","url":null,"abstract":"","PeriodicalId":225304,"journal":{"name":"International Journal of Pharmacy Research & Technology","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123403333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analgesic and Anti Inflammatory Activity of the Leaves of Caryota urens Linn. 山核桃叶的镇痛和抗炎活性。
International Journal of Pharmacy Research & Technology Pub Date : 2019-01-01 DOI: 10.31838/ijprt/02.01.09
R. P. Mariyan, K. Ajay
{"title":"Analgesic and Anti Inflammatory Activity of the Leaves of Caryota urens Linn.","authors":"R. P. Mariyan, K. Ajay","doi":"10.31838/ijprt/02.01.09","DOIUrl":"https://doi.org/10.31838/ijprt/02.01.09","url":null,"abstract":"Caryota urens Linn (Palmae) commonly known as Sugar palm is used in traditional medicine to treat hemicrania and rheumatic swelling. Methanolic extract of plant leaves was used to perform analgesic and anti inflammatory activity. Analgesic study was performed by hot plate and tail flick method and anti-inflammatory effect analyzed by carrageenan induced paw edema. The methanol extract produced significant dose-dependent inhibition of carrageenan-induced rat paw edema. The extract also showed marked analgesic activity. In both the model of analgesic activity methanolic extract of Caryota urens at doses of 200 mg/kg and 400 mg/ kg significantly increase reaction time in rats when compared with control. The dose 400 mg/kg of Caryota urens was highly significant which is comparable with standard in both the studies.Phytochemical investigation of Caryota urens extracts shows presence of phytosterols, tepenoids, flavonoids , tannins and Phenolic compounds which has been responsible for analgesic and anti inflammatory activity. Keywords","PeriodicalId":225304,"journal":{"name":"International Journal of Pharmacy Research & Technology","volume":"54 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132316703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
‘Gellasan’: a Novel Polyionic Matrix for Lipase Immobilization 盖拉桑:一种用于固定化脂肪酶的新型多离子基质
International Journal of Pharmacy Research & Technology Pub Date : 2019-01-01 DOI: 10.31838/ijprt/03.01.02
{"title":"‘Gellasan’: a Novel Polyionic Matrix for Lipase Immobilization","authors":"","doi":"10.31838/ijprt/03.01.02","DOIUrl":"https://doi.org/10.31838/ijprt/03.01.02","url":null,"abstract":"","PeriodicalId":225304,"journal":{"name":"International Journal of Pharmacy Research & Technology","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121851199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A review on Adverse drug reactions monitoring and reporting 药物不良反应监测与报告综述
International Journal of Pharmacy Research & Technology Pub Date : 2019-01-01 DOI: 10.31838/ijprt/09.02.02
Dr.Nambari Hemanth Kumar Y.Prasanth, B.Narendra, K.Upendra, K.Rajesh
{"title":"A review on Adverse drug reactions monitoring and reporting","authors":"Dr.Nambari Hemanth Kumar Y.Prasanth, B.Narendra, K.Upendra, K.Rajesh","doi":"10.31838/ijprt/09.02.02","DOIUrl":"https://doi.org/10.31838/ijprt/09.02.02","url":null,"abstract":"Adverse drug reactions (ADRs) are considered as one among the leading causes of morbidity and mortality. Around \u000010% of hospital admissions are estimated to be due to ADRs and about 5-20% of hospitalized patients experience a \u0000serious ADR. Reporting of ADRs has become an important component of monitoring and evaluation activities \u0000performed in hospitals4. Such ADR reporting programs encourage surveillance for ADRs, promote the reporting of \u0000ADRs and stimulate the education of health professionals regarding potential ADRs. This article reviews about ADR \u0000reporting and monitoring, Classification of Adverse drug reaction, Contrast between Adverse Effects and Adverse \u0000Reactions, Methods of monitoring adverse drug reactions.","PeriodicalId":225304,"journal":{"name":"International Journal of Pharmacy Research & Technology","volume":"3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129130162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Formulation and Evaluation of Nanoparticles containing Losartan Potassium  氯沙坦钾纳米颗粒的制备及评价
International Journal of Pharmacy Research & Technology Pub Date : 2019-01-01 DOI: 10.31838/ijprt/01.01.04
Amar Singh, A. Deep
{"title":"Formulation and Evaluation of Nanoparticles containing Losartan Potassium ","authors":"Amar Singh, A. Deep","doi":"10.31838/ijprt/01.01.04","DOIUrl":"https://doi.org/10.31838/ijprt/01.01.04","url":null,"abstract":"Losartan potassium is an antihypertensive agent used in the treatment of hypertension which has low peak plasma concentration and half-life. It has been selected as candidate for the formulation of sustained release dosage forms. In the present work losartan potassium loaded chitosan nanoparticles were prepared by ionic gelation of chitosan with tripolyphosphate anions. Nanoparticles of different core: coat ratio were formulated and evaluated for drug content, loading efficiency, particles size, zeta potential, In vitro drug release and stability studies. Scanning Electron Microscopy indicated that the nanoparticles were found to be in nanometer range and showed ideal surface morphology. Differ ential scanning calorimetry analysis indicated that there were no chemical interactions between drug and polymer and stability of drug. In vitro release behavior from all the drug loaded batches were found to follow zero order and provided sustained release over a period of 24 hours. No appreciable difference was observed in the extent of degradation of product during 60 days in which nanoparticles were stored at various temperatures. The developed formulation overcomes and could possibility be advantageous in terms of sustained release dosage forms of losartan potassium.","PeriodicalId":225304,"journal":{"name":"International Journal of Pharmacy Research & Technology","volume":"67 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121547127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Current Approaches on Gastro Retentive Drug Delivery System: An Overview 胃保留性给药系统的最新研究进展综述
International Journal of Pharmacy Research & Technology Pub Date : 2019-01-01 DOI: 10.31838/ijprt/09.02.04
{"title":"Current Approaches on Gastro Retentive Drug Delivery System: An Overview","authors":"","doi":"10.31838/ijprt/09.02.04","DOIUrl":"https://doi.org/10.31838/ijprt/09.02.04","url":null,"abstract":"","PeriodicalId":225304,"journal":{"name":"International Journal of Pharmacy Research & Technology","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128505984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Electroporation: An Emerging Technique For Drug Delivery 电穿孔:一种新兴的药物递送技术
International Journal of Pharmacy Research & Technology Pub Date : 2019-01-01 DOI: 10.31838/ijprt/04.01.02
{"title":"Electroporation: An Emerging Technique For Drug Delivery","authors":"","doi":"10.31838/ijprt/04.01.02","DOIUrl":"https://doi.org/10.31838/ijprt/04.01.02","url":null,"abstract":"","PeriodicalId":225304,"journal":{"name":"International Journal of Pharmacy Research & Technology","volume":"110 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115512195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A Preliminary Investigation of Moringa Oleifera Lam Gum As a Pharmaceutical Excipient  辣木林胶作为药用辅料的初步研究
International Journal of Pharmacy Research & Technology Pub Date : 2019-01-01 DOI: 10.31838/ijprt/01.01.03
D. Shah, V. Jain, H. Dalvadi, Vinodkumar D Ramani, K. G. Patel, M. G. Saralai, G. K. Jani
{"title":"A Preliminary Investigation of Moringa Oleifera Lam Gum As a Pharmaceutical Excipient ","authors":"D. Shah, V. Jain, H. Dalvadi, Vinodkumar D Ramani, K. G. Patel, M. G. Saralai, G. K. Jani","doi":"10.31838/ijprt/01.01.03","DOIUrl":"https://doi.org/10.31838/ijprt/01.01.03","url":null,"abstract":"Mother nature has gifted India with great variety of flora and fauna. Since centuries man has made an effective use of material from natural origins in the medical & pharmaceutical field. In present study, Moringa oleifera Lam., was explored as a pharmaceutical excipient. Various physico-chemical properties like particle size, solubility, swelling ratio, flow property and compressibility were measured and compared with other materials also. Aceclofenac tablets containing Moringa were prepared and evaluated for various quality control parameters like hardness, friability, wetting time and disintegration time. Drug releases from Aceclofenac tablets were performed. Finally, stability study of optimized batch was carried out. It was observed that Moringa gum had excellent swelling ratio, flow property and compressibility. Batch F3 was considered as optimized batch due to lesser disintegration time, hardness & friability are within the limit. Tablets are stable after stability study.","PeriodicalId":225304,"journal":{"name":"International Journal of Pharmacy Research & Technology","volume":"95 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124603848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Druggability of Genome 基因组的可药物性
International Journal of Pharmacy Research & Technology Pub Date : 2019-01-01 DOI: 10.31838/ijprt/02.02.01
{"title":"Druggability of Genome","authors":"","doi":"10.31838/ijprt/02.02.01","DOIUrl":"https://doi.org/10.31838/ijprt/02.02.01","url":null,"abstract":"","PeriodicalId":225304,"journal":{"name":"International Journal of Pharmacy Research & Technology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126298085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A NOVEL STABILITY INDICATING RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR THE DETERMINATION OF CLOPIDOGREL IN BULK AND ITS DOSAGE FORMS  建立了一种新的稳定性指示反相高效液相色谱法测定散装氯吡格雷及其剂型
International Journal of Pharmacy Research & Technology Pub Date : 2019-01-01 DOI: 10.31838/ijprt/09.02.01
Y.Venkateswararao, K.Sujana
{"title":"A NOVEL STABILITY INDICATING RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR THE DETERMINATION OF CLOPIDOGREL IN BULK AND ITS DOSAGE FORMS ","authors":"Y.Venkateswararao, K.Sujana","doi":"10.31838/ijprt/09.02.01","DOIUrl":"https://doi.org/10.31838/ijprt/09.02.01","url":null,"abstract":"A Simple, rapid and sensitive stability indicating Reverse Phase High Performance Liquid Chromatographic method \u0000was developed for the estimation of Clopidogrel (CLG) in presence of its oxidative, acid, alkali and thermal \u0000degradation and neutrality of drug. The method was validated as per International Conference on Harmonization \u0000(ICH) guidelines. The mobile phase used in this study is a mixture of Acetonitrile: OPA - Ortho phosphoric acid \u0000buffer (50:50v/v). Stationary phase was Discovery AltimaC18 (150mm x 4.6 mm, 5μm) reverse phase column at 30oC \u0000ambient temperature. The analysis was performed with run time of 10.0 minutes at a flow rate of 1.00ml/min. The \u0000CLG was monitored at 240nm with UV detection and CLG was eluted at 2.7min. The method was linear (0.9998) at \u0000concentration ranging from 25to150μg/ml, precise (intra-day relative standard deviation (RSD) and inter-day RSD \u0000values < 1.0%), accurate (mean recovery = 99.41%), specific and robust. Detection and quantification limits were \u000018.7μg/ml and 112.5μg/ml, estimated from linearity by regression analysis. The results showed that the proposed \u0000method was suitable for rapid determination of clopidogrel in bulk dosage forms.","PeriodicalId":225304,"journal":{"name":"International Journal of Pharmacy Research & Technology","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122145141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信