International Journal of Pharmacy Research & Technology最新文献_第3页

Neuraminidase Inhibitors – For Effective Treatment of Influenza 神经氨酸酶抑制剂-有效治疗流感

International Journal of Pharmacy Research & Technology Pub Date : 2019-01-01 DOI: 10.31838/ijprt/04.01.04

引用次数: 0

Changes in the number of the species and fungal populations colonizing decomposing wheat crop residues 分解小麦作物残茬的菌种和真菌种群数量的变化

International Journal of Pharmacy Research & Technology Pub Date : 2019-01-01 DOI: 10.31838/ijprt/07.02.04

Raj Singh, A. Rani, Permod Kumar, C. Singh, Gyanika Shukla

引用次数: 4

HPLC Method Development and Validation for Estimation of Eperisone Hydrochloride from Bulk and Marketed Formulation 盐酸依培立松原料药和市售制剂HPLC测定方法的建立与验证

International Journal of Pharmacy Research & Technology Pub Date : 2019-01-01 DOI: 10.31838/ijprt/09.01.02

Monika Kumbhar, Shapali Bagde, M. Karpe, Vilasroa Kadam

{"title":"HPLC Method Development and Validation for Estimation of Eperisone Hydrochloride from Bulk and Marketed Formulation","authors":"Monika Kumbhar, Shapali Bagde, M. Karpe, Vilasroa Kadam","doi":"10.31838/ijprt/09.01.02","DOIUrl":"https://doi.org/10.31838/ijprt/09.01.02","url":null,"abstract":"Rapid, accurate and precise method for identification and quantitation of Eperisone Hydrochloride (EPE) was \u0000developed by reversed-phase high performance liquid chromatographic (RP-HPLC) and validated. The solvent system \u0000and wavelength were optimized in order to maximize the sensitivity of the proposed method, Eperisone \u0000Hydrochloride shows the maximum absorbance at 255 nm. The Agilent HPLC 1200 series system, employed with \u0000software EZ Chrom Elite was used for proposed analytical work. Column chromatographic development was carried \u0000out with the help of reversed-phase mode using HiQSil C18 (4.6 mm X 250 mm, 5 mm i.d., 5 μm particle size). The \u0000optimized mobile phase consisted of Methanol: Double distilled water (pH maintain 3) (90:10 %v/v) as the mobile \u0000phase and detection wavelength of 255 nm.Flow rate was kept at 0.8 mL min-1. Drug- Eperisone Hydrochloride was \u0000well resolved and retained at 2.9 min. Performance characteristics of HPLC method for estimation of EPE in bulk and \u0000its marketed dosage form were statistically validated as per recommendations of ICH guidelines of analytical method \u0000validation. This method was validated for accuracy, precision, linearity, LOD & LOQ of sample solution.The HPLC \u0000method was found to be linear with R2 value of 0.9942 and across the range 10 μg/ml- 90 μg/ml. The LOD 0.645 \u0000μg/ml and LQD values were found to be 0.645 μg/ml and 1.957μg/ml respectively. The method was found to be \u0000accurate, precise, robust and economical for the analysis of EPE from bulk and its formulation. Thus this method can \u0000be safely and successful employed for analysis of routine samples and quality control of drugs in pharmaceutical \u0000formulations.","PeriodicalId":225304,"journal":{"name":"International Journal of Pharmacy Research & Technology","volume":"80 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126361550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Piperine : A Bioenhancer 胡椒碱:一种生物增强剂

International Journal of Pharmacy Research & Technology Pub Date : 2019-01-01 DOI: 10.31838/ijprt/01.01.01

Amar Singh, A. Deep

{"title":"Piperine : A Bioenhancer","authors":"Amar Singh, A. Deep","doi":"10.31838/ijprt/01.01.01","DOIUrl":"https://doi.org/10.31838/ijprt/01.01.01","url":null,"abstract":"Piperine is a major alkaloid of Pepper fruits belonging to family Piperaceae which has a number of medicinal proper-ties. Pepper fruits are one of them which have been established as bioenhancer for some selected drugs. In Ayureveda since centuries it is called as ÂYogvahiÂ. Black pepper fruits are the supporting evidence where piperine was one of the ingredients of ÂTrikatuÂ. Black pepper fruits are used in different food, drink, dessert, perfume as a brandy flavors and preservative of pickles. It is well known as ÂKing of SpicesÂ. Piperine enhances the bioavailability of structurally and therapeutically differ-ent drugs, either by increasing the absorption or by delaying the metabolism of the drug or by a combination of both processes. It is evident that black pepper fruits have been used as bio-enhancer in allopathic system of medicine. Piperine has been used as bioenhancer for certain antibacterial- antibiotics with promising results. The interaction of piperine with drug-metabolizing enzymes is responsible for oxidation, hydroxylation and glucuronidation. Piperine appears to top in the list of bioenhancers as it has been used as bioenhancer for Allopathic, Ayurvedic and Unani drugs. Piperine enhances Cmax of different drugs significantly.","PeriodicalId":225304,"journal":{"name":"International Journal of Pharmacy Research & Technology","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126731279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

MEMS: Novel Means of Smart Drug Delivery MEMS:智能药物传递的新手段

International Journal of Pharmacy Research & Technology Pub Date : 2019-01-01 DOI: 10.31838/ijprt/04.01.05

引用次数: 1

Novel Concept of Drug Delivery Based on Chronotherapy: A Review 基于时间疗法的给药新概念综述

International Journal of Pharmacy Research & Technology Pub Date : 2019-01-01 DOI: 10.31838/ijprt/04.02.05

引用次数: 2

Medicinal vegetal use by traditional healers in Ekiti State of Nigeria for diabetes treatment 尼日利亚埃基蒂州传统治疗师使用药用植物治疗糖尿病

International Journal of Pharmacy Research & Technology Pub Date : 2019-01-01 DOI: 10.31838/ijprt/08.01.03

F. Akharaiyi

引用次数: 4

FORMULATION AND EVALUATION OF ACTIVATED CHARCOAL PEEL OFF MASK 活性炭剥离面膜的配方及评价

International Journal of Pharmacy Research & Technology Pub Date : 2019-01-01 DOI: 10.31838/ijprt/09.02.06

Sweta V.Kulkarni, Dr.Arun K.Gupta, S. Bhawsar

{"title":"FORMULATION AND EVALUATION OF ACTIVATED CHARCOAL PEEL OFF MASK","authors":"Sweta V.Kulkarni, Dr.Arun K.Gupta, S. Bhawsar","doi":"10.31838/ijprt/09.02.06","DOIUrl":"https://doi.org/10.31838/ijprt/09.02.06","url":null,"abstract":"Skin is a very sensitive and protective layer of the human body which is exposed to environmental pollution hence, it \u0000is very essential to protect the skin. The facial skin can be protected by applying various cosmetics intended specially \u0000for facial application, It can be a cream, lotion face mask or peel off mask etc. Peel off mask is the type of dosage form \u0000which is gently applied onto the facial skin surface and is peeled off after few minutes of its application. It is used as \u0000the remedy to treat facial skin related problems such as wrinkles, ageing, acne and mainly used to open the closed \u0000pores due to deposition of dust. Its main role is to Stimulate the metabolism due to its occlusive effect. Activated \u0000charcoal is being added as an active ingredient in this formulation. The most important characteristic of an activated \u0000carbon is its adsorbant activity. Using it as an active ingredient in peel off mask, it adds to its value by enhancing the \u0000role of peel off mask by absorbing dust particles and opening the clogged pores. Literature survey reveals many \u0000papers related to formulation of herbal peel off masks, but no any reported paper was found on Activated Charcoal \u0000peel off mask. In this paper, we have formulated Activated Charcoal peel off mask and Evaluated it by using various \u0000tests methods. The formulation showed overwhelming results after its application on healthy female volunteers.","PeriodicalId":225304,"journal":{"name":"International Journal of Pharmacy Research & Technology","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126821292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Comparison of Antioxidant and Free Radical Scavenging Potential of Polyherbal Formulations of SIDITI SIDITI多草药制剂抗氧化和自由基清除能力的比较

International Journal of Pharmacy Research & Technology Pub Date : 2019-01-01 DOI: 10.31838/ijprt/02.02.10

引用次数: 1

INFLUENCE OF THIRD PARTY SYSTEM ON RATIONAL DRUG USE IN A TERTIARY HOSPITAL IN BENIN CITY NIGERIA: EXPLORING SYSTEM DYNAMICS 第三方制度对尼日利亚贝宁市某三级医院合理用药的影响:系统动力学探讨

International Journal of Pharmacy Research & Technology Pub Date : 2019-01-01 DOI: 10.31838/ijprt/09.01.06

Isiboge Pd, Ogbonna Bo, G. Ele, Orji Ec, Ejim Ce, Onyeyili An, Uzodinma Su, N. Ajagu, Iweh Mi

{"title":"INFLUENCE OF THIRD PARTY SYSTEM ON RATIONAL DRUG USE IN A TERTIARY HOSPITAL IN BENIN CITY NIGERIA: EXPLORING SYSTEM DYNAMICS","authors":"Isiboge Pd, Ogbonna Bo, G. Ele, Orji Ec, Ejim Ce, Onyeyili An, Uzodinma Su, N. Ajagu, Iweh Mi","doi":"10.31838/ijprt/09.01.06","DOIUrl":"https://doi.org/10.31838/ijprt/09.01.06","url":null,"abstract":"Catastrophic spending is a major limitation of access to quality health care especially in developing countries. Health \u0000insurance enables resource pooling and burden sharing serves as a way of eliminating the challenges. The study \u0000assessed the level of rational drug use in National Health Insurance Scheme (NHIS) andnon-NHIS facility based on \u0000World Health Organizations (WHO) Standard Drug Use Indicators to generate data for planning and policy. The \u0000study was a cross-sectional survey. Drug utilization in the NHIS and non-NHIS facilities was benchmarked withthe \u0000WHO Standard Drug Use Indicators.The data was summarized with descriptive statistics. The average number of \u0000drugs prescribed per encounter was 3.92 (with range 3.80 3.97) for the NHIS clinics and 3.15 (with range 3.05 \u00003.30) for the General Practice Clinic (GPC). The average percentage of drugs prescribed from the National essential \u0000drugs list was 80.46 (range 40.18 92.90) and 90.10 (range of 86.38 94.37) for the NHIS and GPC clinics respective. \u0000The average percentage of encounter with antibiotics was 12.77 (range 6.48 15.44) and 12.86 (range 10.22 15.46) \u0000for the NHIS and GPC clinics respectively. the third party payment system operational in the NHIS facility negatively \u0000influenced drug utilization.","PeriodicalId":225304,"journal":{"name":"International Journal of Pharmacy Research & Technology","volume":"92 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133631128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1