The Egyptian Journal of Chemistry最新文献

Synthesis, Characterization and Biological Evaluation of Benzimidazole and Benzindazole Derivatives as Anti-hypertensive Agents 苯并咪唑及其衍生物抗高血压药物的合成、表征及生物学评价

The Egyptian Journal of Chemistry Pub Date : 2021-06-14 DOI: 10.21608/EJCHEM.2021.79840.3931

Silky Sethy, S. Mandal, E. Ewies, Neerupma Dhiman, A. Garg

{"title":"Synthesis, Characterization and Biological Evaluation of Benzimidazole and Benzindazole Derivatives as Anti-hypertensive Agents","authors":"Silky Sethy, S. Mandal, E. Ewies, Neerupma Dhiman, A. Garg","doi":"10.21608/EJCHEM.2021.79840.3931","DOIUrl":"https://doi.org/10.21608/EJCHEM.2021.79840.3931","url":null,"abstract":"A substituted benzimidazole and benzindazole derivatives had been synthesized having antihypertensive activity through antagonizing the angiotensin II (Ang II) receptors. The in vivo antihypertensive activity of the compounds was done with acute renal hypertension model. Two compounds TG 1 and TG 3 were found to have antihypertensive activity comparable to Telmisartan which is a prototype for Angiotensin II receptor antagonists class of drugs.In an antihypertensive study the compounds TG 1, TG 2 and TG 3 had systolic blood pressures of 147.2 mm/Hg, 168.2 mm/Hg, and 126.3 mm/Hg, respectively. This systolic blood pressure was lower than the disease control vehicle-treated rodents, which had a systolic blood pressure of 167.2 mm/Hg. The diastolic blood pressure was 119.7 mm/Hg, 124.7 mm/Hg and 88.83 mm/Hg, respectively and that of the disease control vehicle-treated rodents was 122.3 mm/Hg. TG 3 had comparable decrease in the MABP to Telmisartan. These encouraging results make compound TG 3 effective anti-hypertensive drug candidate and worthy of further investigation.","PeriodicalId":22429,"journal":{"name":"The Egyptian Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75251123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A minireview on Applications of the metal-organic framework and carbon dots in dye photodegradation to protect the aquatic environment from organic pollutants 金属有机骨架和碳点在染料光降解中的应用综述

The Egyptian Journal of Chemistry Pub Date : 2021-06-13 DOI: 10.21608/EJCHEM.2021.72540.3602

Amira Abd Elkhalk, Mohamed Batiha

引用次数: 0

Optimized Synthesis of Biopolymer-Based Zinc Oxide Nanoparticles and Evaluation of Their Antibacterial Activity 生物聚合物基氧化锌纳米颗粒的优化合成及其抗菌活性评价

The Egyptian Journal of Chemistry Pub Date : 2021-06-13 DOI: 10.21608/EJCHEM.2021.75677.3709

T. Hassanein, A. Mohammed, Wael Sabry Mohamed, R. Sobh, Magdy, Kandil Zahran

{"title":"Optimized Synthesis of Biopolymer-Based Zinc Oxide Nanoparticles and Evaluation of Their Antibacterial Activity","authors":"T. Hassanein, A. Mohammed, Wael Sabry Mohamed, R. Sobh, Magdy, Kandil Zahran","doi":"10.21608/EJCHEM.2021.75677.3709","DOIUrl":"https://doi.org/10.21608/EJCHEM.2021.75677.3709","url":null,"abstract":"Owing to their unique properties, zinc oxide nanoparticles (ZnO NPs) have a broad range of exciting applications. However, the problem of nanoparticles aggregation remains challenging. So, biopolymers of polysaccharides can provide green and promising stabilizers as alternatives to the current toxic chemical stabilizers during ZnO NPs synthesis. The main idea in this investigation is to tune ZnO NPs with an appropriate texture, shape, and size for antibacterial application. So, this work compares the use of three different eco-friendly stabilizers namely starch, carboxymethyl cellulose, and hydroxyethyl cellulose as alternatives capping agents in the fabrication of ZnO NPs at various times. The optimized ZnO NPs sample was obtained using starch as the optimum stabilizer at reaction conditions of 0.5 h, room temperature (25 °C), 1:2 )MZn:MNaOH) ratio and 1% (w/v) starch concentration. The optical, texture, and structural properties of prepared ZnO NPs were characterized by UV–Vis, DLS, zeta potential, FT-IR, and TEM techniques. ZnO NPs showed a mean zeta potential of −21.6 mV, explaining that they are moderately stable. The analysis by TEM confirmed that the NPs were spherical and have an average size of 23 nm. The antibacterial properties of ZnO NPs against Gram-positive (Bacillus subtilis and Staphylococcus epidermidis) and Gramnegative (Enterobacter cloacae and Escherichia coli) bacteria were evaluated based on the zone of inhibition (ZOI) values expressed in mm. The results showed promising performances for their antibacterial activity against the tested bacteria which indicated a strong antibacterial activity of ZnO NPs against B. subtilis, S. epidermidis, and E. cloacae with ZOI values of 17, 14 and 16 mm, respectively, and it showed moderate activity against E. coli (ZOI = 10 mm). The synthesis of biopolymer stabilized ZnO NPs by this approach could be eco-friendly and cost-effective and synthesized ZnO NPs can serve as promising antibacterial agents.","PeriodicalId":22429,"journal":{"name":"The Egyptian Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87980872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Seawater Reinforces Synthesis of Mesoporous and Microporous Zeolites from Egyptian Fly Ash for Removal Ions of Cadmium, Iron, Nickel, and Lead from Artificially Contaminated Water 海水强化埃及飞灰合成介孔和微孔沸石去除人工污染水中镉、铁、镍和铅离子

The Egyptian Journal of Chemistry Pub Date : 2021-06-13 DOI: 10.21608/EJCHEM.2021.73834.3661

L. Ibrahim, E. ElSayed

{"title":"Seawater Reinforces Synthesis of Mesoporous and Microporous Zeolites from Egyptian Fly Ash for Removal Ions of Cadmium, Iron, Nickel, and Lead from Artificially Contaminated Water","authors":"L. Ibrahim, E. ElSayed","doi":"10.21608/EJCHEM.2021.73834.3661","DOIUrl":"https://doi.org/10.21608/EJCHEM.2021.73834.3661","url":null,"abstract":"This study focuses on the production of mesoporous and microporous zeolites via fusion pre-treating fly ash with NaOH followed by hydrothermal treatment utilizing seawater. Three pretreatments for fly ash were carried out utilizing 1:1, 1.2:1, and 1.4:1 of NaOH:fly ash ratio to compare the removal efficiency for cadmium Cd(II), iron Fe(II), nickel Ni(II), and lead Pb(II) from artificially contaminated water. The impacts of several variables including concentrations, weights, pH, and contact times were examined to acquire knowledge on the adsorption rate. X-Ray Diffraction (XRD), Scanning Electron Microscope (SEM), and Brunaauer-Emmett-Teller (BET) were utilized to investigate zeolite structures. N2 adsorption/desorption isotherms demonstrated that the synthetic zeolites were mesoporous and microporous materials with a higher specific area (347, 240, and 127 m2/g) than the values for raw fly ash (15m2/g). The X-ray diffraction outcome suggested that the synthetic products mainly belonged to phillipsite, carbonate cancrinite, and hydroxysodalite. These outcomes showed that fly ash and seawater from power plants are appropriate for synthesizing high-quality zeolites. For contaminated water treatment, the products are effective for removal Cd(II), Fe(II), Ni(II), and Pb(II) at pH 7, contact time 45 min, and dose 1 g/L. Zeolites recycling outcomes showed that the removal efficiency of investigated metal ions by Z1, Z2, and Z3 was reduced by an average of 7%, 5%, and 3% after regeneration.","PeriodicalId":22429,"journal":{"name":"The Egyptian Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74981620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Metabolic syndrome and the risk of kidney diseases: the impact of life style modification 代谢综合征与肾脏疾病的风险:生活方式改变的影响

The Egyptian Journal of Chemistry Pub Date : 2021-06-09 DOI: 10.21608/EJCHEM.2021.78093.3818

M. Abdel-Moaty, Salwa M. El Shebini, Nihad H. Ahmed, H. Essa, S. Tapozada

引用次数: 0

Phytochemical investigation and differential effects of Cestrum elegans isolated compounds as antimicrobial and virucidal against hepatitis A virus 秀丽弓形虫分离化合物抗甲型肝炎病毒和抗病毒作用的植物化学研究及差异效应

The Egyptian Journal of Chemistry Pub Date : 2021-06-08 DOI: 10.21608/EJCHEM.2021.71934.3581

A. Abdel-Aziz, N. Elwan, Mona Abdel-Motagaly, S. Nasr, M. Ghareeb

引用次数: 4

Fatty Acid and Amino Acid Composition of Citrullus Colocynthis Seeds Growing in Algeria 阿尔及利亚产瓜泥种子脂肪酸和氨基酸组成

The Egyptian Journal of Chemistry Pub Date : 2021-06-08 DOI: 10.21608/EJCHEM.2021.73414.3627

B. Boulanouar, M. Bireche, Abdelaziz Gherib, Á. Gil-Izquierdo, R. Domínguez‐Perles, M. Ghareeb

{"title":"Fatty Acid and Amino Acid Composition of Citrullus Colocynthis Seeds Growing in Algeria","authors":"B. Boulanouar, M. Bireche, Abdelaziz Gherib, Á. Gil-Izquierdo, R. Domínguez‐Perles, M. Ghareeb","doi":"10.21608/EJCHEM.2021.73414.3627","DOIUrl":"https://doi.org/10.21608/EJCHEM.2021.73414.3627","url":null,"abstract":"Citrullus colocynthis is an herbaceous perennial wild species of the Cucurbitaceae family, used in traditional medicine in the treatment of diabetes mellitus. In the present work, C. colocynthis seed oils have been assessed for their fatty acids profile and concentration by Gas Chromatography–Mass Spectrometry (GC-MS), while oil and protein extracts were investigated in respect to their amino acid compositions by using Ultra HighPerformance Liquid Chromatography-Electrospray Ionization-Triple Quadrupole Mass Spectrometry (UHPLCESI-QqQ-MS/MS) instrumentation. Results revealed that the predominant fatty acids in C. colocynthis seeds were linoleic (70.7 %), oleic (10.9 %), palmitic (8.3 %), and stearic (7.8 %) acids. On other hand, the analysis of the free amino acids content noticed the presence of threonine (0.32 μgmL), valine (0.26 μgmL), and tryptophan (0.19 μgmL). Besides, the C. colocynthis seeds oil contained the non-essential amino acids like serine (0.29 μgmL), ethanolamine (0.18 μgmL), glycine (0.25 μgmL) and aspartic acid (0.12 μgmL). In conclusion, the results obtained revealed the valuable nutritional value of C. colocynthis and derived co-products, suggesting its suitability to be used as a nutritional ingredient and to be considered in the development of dietary supplements.","PeriodicalId":22429,"journal":{"name":"The Egyptian Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86129460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Application of Water Safety Plans to Improve Desalination Water Supply at Matrouh Governorate, Egypt 在埃及马特鲁省应用水安全计划改善海水淡化水供应

The Egyptian Journal of Chemistry Pub Date : 2021-06-06 DOI: 10.21608/EJCHEM.2021.76398.3738

Waleed Hosni Elsayed Mohamed, M. S. Ibrahim, R. Wahaab, Amany F. Hasballah

引用次数: 0

Cost-effective Clean Electrochemical Preparation of Ferric Chloride and its Applications 低成本清洁氯化铁的电化学制备及其应用

The Egyptian Journal of Chemistry Pub Date : 2021-06-06 DOI: 10.21608/EJCHEM.2021.75921.3717

M. Abdel-Fatah, S. Hawash, H. Shaarawy

{"title":"Cost-effective Clean Electrochemical Preparation of Ferric Chloride and its Applications","authors":"M. Abdel-Fatah, S. Hawash, H. Shaarawy","doi":"10.21608/EJCHEM.2021.75921.3717","DOIUrl":"https://doi.org/10.21608/EJCHEM.2021.75921.3717","url":null,"abstract":"In this investigation, a green, cost-effective clean electrochemical process for preparing a highly concentrated ferric chloride (FeCl3) solution has been proposed. Many operating conditions, affected the used anodic dissolution process for FeCl3 production, were studied. Generating ferrous hydroxide electrochemically then dissolving it by hydrochloric acid and oxidized with chlorine free mixed oxidant, were proceeded steps to reach the production of our target ferric chloride. It is a green, clean, and novel process because it is environmentally and industrial safer than the traditional production technology. The most important studied experimental variables were applied like applied current density, sodium chloride concentration, electrolyte pH, at the most controlling operating parameter which is optimum electrolysis time. Experimental results revealed that optimum current density was 300 mA/cm; using 30gm/L saline solution, electrodes gap distance 5 cm, and stirring rate 150 rpm at pH 6.5 for 270 minutes, respectively. At these optimal operating parameters, 40% FeCl3 concentration can be prepared to consume 202 watts/liter of high quality with low capital, & operating costs. The economic indicators show that the running cost of production of 40% ferric chloride solution using the proposed cleaner electrochemical production technology will be 241.66$/ton and the suggested price is 450$/ton with a net profit of 156$ with high cash flow using the proposed green technology. The proposed methodology for FeCl3 production reviews the importance of using cleaner production and sustainable development indicators.","PeriodicalId":22429,"journal":{"name":"The Egyptian Journal of Chemistry","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79158949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Structural and some physical properties of Sodium Boro-phosphate Glass Containing Mill Scale. 含磨垢硼磷酸钠玻璃的结构及一些物理性能。

The Egyptian Journal of Chemistry Pub Date : 2021-06-06 DOI: 10.21608/EJCHEM.2021.68425.3494

A. Sayed

引用次数: 0