The Animal Biology最新文献

{"title":"Pathological anatomic changes among laboratory rats in case of experimental infection with the larvae of the nematode Eustrongylides excisus (Nematoda: Dioctophymatidae)","authors":"S. Honcharov","doi":"10.15407/animbiol22.01.003","DOIUrl":"https://doi.org/10.15407/animbiol22.01.003","url":null,"abstract":"The aim of the research was to model the experimental infection in laboratory rats with the larvae of the nematodes Eustrongylides excisus and documenting the macroscopic changes in organs and tissues of the animals. With a purpose of creating the best conditions for the nematodes larvae’s survival the animals were divided into 4 groups. The first group included intact animals. The rats of groups II and III were orally given the 1 % chlorine hydride solution in the amount of 0.5 and 1 ml respectively. Group IV was a control. The rate of the larvae survival in groups I, II and III counted, respectively, 18, 38 and 52 % of the general amount of the larvae put into the organisms of the rats. Among the invaded rats next chang es of the clinical conditions were noticed: general weakness, absence of appetite, pain and tension in the abdominal wall etc. After euthanasia and followed autopsy the symptoms of se rofibrous (20 % of the invaded animals) and fibrinopurulent (66.6 %) peritonitis were noticed. It also showed the signs of the enteral failure syndrome (73.3 %) and the abdominal layers adhesion (86.6 %). Microabscesses under the liver capsule were noticed as well, in 26.6 % of the experimentally infected rats. Pathological changes in the thoracic cavity organs, in part in the heart (pericard and heart sac hemorrhages) and in the lungs (congestive hyperemia and pulmonary edema) have been found in 60 % cases, and in kidneys in 73.3 % cases. Symptoms of catarrhal and hemorrhagic gastritis were observed. The positive correlative connection between the parasitic survival percentage in the organisms of rats and the depth and difficulty of the pathological process was determined.","PeriodicalId":22372,"journal":{"name":"The Animal Biology","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90857613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hematological indices of rats after administration of enrofloxacin as a subunit of polymer","authors":"O. Zelenina, D. Ostapiv, V. Vlizlo, I. Dron, S. I. Vinnytska","doi":"10.15407/animbiol22.01.026","DOIUrl":"https://doi.org/10.15407/animbiol22.01.026","url":null,"abstract":"The influence of antibiotic enrofloxacin and PEG-400 polymer complex on hemoglobin content, red and white blood cell count, and blood leukogram state of apparently healthy rats has been studied. The enrofloxacin contains reactive carboxyl groups in the molecule on the 7 th day of the experiment.","PeriodicalId":22372,"journal":{"name":"The Animal Biology","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89425486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The association of eustrongylidosis with other types of parasitic invasions of the predatory fishes in the natural waters of Southern Ukraine","authors":"S. Honcharov","doi":"10.15407/animbiol21.04.022","DOIUrl":"https://doi.org/10.15407/animbiol21.04.022","url":null,"abstract":"The article presents the result of the research of predatory fishes — sander (Sander lucioperca Linnaeus, 1758), perch (Perca fluviatilis Linnaeus, 1758) and pike (Esox lucius Linnaeus, 1758) in the waters of the Dnipro-Buh estuary and in the delta of the Dnipro river. The possible associations of eustrongylidosis with other types of parasitic invasions of fishes have been established. It has been revealed up that the researched fish has been invaded mostly by such agents of parasitic diseases as digenetic trematodes and nematodes — 35.6 % and 31.8 % respectively. The least common group of parasites affecting commercial fishes was acanthocephalides — 0.71 %. The invasion of perches by the diplostomosis agents was noticed. The invasion extensiveness (IE) counted 50.7 %, and the invasion intensiveness (II) counted 2–41 samples. Other parasitic diseases affecting perches were paracoenogonymonosis (ІE — 15.3 %, ІІ — 7–31 samples); post diplostomosis (ІE — 9.97 %, ІІ — 87–118 metacecaria); dactylogyrosis (ІE — 37.2 %, ІІ — 5–14 samples); lavral trienophorosis (ІE — 1.66 %, ІІ — 2–5 cysts); eustrongylidosis (ІE ІІ — 1–3 samples);argulosis (ІE — 12 %, ІІ — 6–18 samples); ergazylosis (ЕІ — 6.02 %, ІІ — 11–26 maxillopods); The parasitic fauna of pikes is characterized by the agents of diplopstomosis (ІE — 62 %, ІІ — 3–17 larvae); paracoegonimosis (ІE — 42.7 %, ІІ — 1–38 metacecaria); postodiplostomosis (ІE — 10.7 %, ІІ — 23–51 sam-ples); dactylogyrosis (ІE — 17.8 %, ІІ — 2–15 samples); diplozoonosis (ІE — 0.67 %, ІІ — 1 sample); trienophorosis (ІE — 56.5 %, ІІ — 1–9 samples); valiporosis (ІE — 24.9 %, ІІ — 1–11 plerocercoids); eustrongylidosis (ІE — 58.9 %, ІІ — 1–13 larvae); rafidoscarosis (ІE — 76.4 %, ІІ — 8–31 nematodes); pseudoekhinorinchosis (ІE — 2.02 %, ІІ — 2–9 acanthocephala); argulosis (ІE — 28.2 %, ІІ — 2–63 parasites). The parasitic invasions of slander were also registered: for example, with diplopstomosis (ІE — 52.7 %, ІІ — 1–13 parasites); paracoenogonymonosis (ІE — 15.3 %, ІІ — 1–17 metacecaria); postodiplostomosis (ІE — 8.8 %, ІІ — 5–84 larvae); dactylogyrosis (ІE — 31 %, ІІ — 2–23 samples); valiporosis (ІE — 5.9 %, ІІ — 1–2 plerocercoids); eustrongylidosis (ІE — 58.1 %, ІІ — 1–9 samples); rafidoscarosis (ІE — 18.2 %, ІІ — 5–8 nematodes); pseudo-ekhinorinchosis (ІE — 0.49 %, ІІ — 2 acanthocephala); ergazylosis (IE — 47.2 %, ІІ — 7–28 maxillopods).","PeriodicalId":22372,"journal":{"name":"The Animal Biology","volume":"75 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86170259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The research of epizootic situation of avian influenza H1N1 and H7N9 in subtypes variability on the territory of Ukraine","authors":"S. Buriachenko, B. Stegniy","doi":"10.15407/animbiol21.04.009","DOIUrl":"https://doi.org/10.15407/animbiol21.04.009","url":null,"abstract":"The epizootic situation of avian influenza in birds and humans in Ukraine, caused by subtypes A H1N1 and H7N9 is being reviewed. A comparative analysis of the existing methods for diagnosing avian influenza in birds and humans and their suitability is shown, and the variability of avian influenza genetic markers in birds and humans is determined. An epizootic situation on the prevalence of avian influenza in the world and Ukraine is presented, vari ous methods for diagnosing avian influenza virus in comparison are analyzed, the variability of genetic markers of avian influenza in the two subtypes is analyzed. It is shown that the natural reservoir of the virus and the cause of the spread of the epizootic are migratory waterfowl, which, due to their natural resistance, are the least susceptible to infection and can travel long distances during migration. According to the literature, some strains of the avian in fluenza virus, in particular H1N1 and H7N9, are unsafe for humans and often lead to death. Research data obtained from diagnostic or biological material must be confirmed by the specificity of the method and not only molecular — biological to establish their reliability. There is a need to quickly obtain research results. For successful measures that will lead to a reduction in mortality and reduce the risk of spreading the infection, it is necessary to conduct regular monitoring of the foci of infection, epidemics, as well as its timely diagnosis. Polymerase chain reaction (PCR), which is accepted in many laboratories around the world, is of great practical importance for the diagnosis of avian influenza and other infectious diseases. However, this method requires the use of expensive equipment and consumables and for many laboratories it is an expensive and not a cost-effective method.","PeriodicalId":22372,"journal":{"name":"The Animal Biology","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89708467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of ethylthiosulfаnylate and Chrome(VI) on the pro/antioxidant system in rats blood","authors":"B. Kotyk, R. Iskra, O. Sushko, O. Slivinska, G. Klymets, O. Buchko, A. Pylypets, V. I. Pryimych","doi":"10.15407/animbiol21.04.038","DOIUrl":"https://doi.org/10.15407/animbiol21.04.038","url":null,"abstract":"physiological solution daily for 7 days. Rats of groups VI and VII were intragastrically administered with ethylthio sulfanylate oily solution at a rate of 100 mg/kg of body weight daily for 14 days, than animals were intraperitoneally injected K 2 Cr 2 O 7 in a dose of 2,5 mg Cr(VI)/kg body weight daily for 7 (group VI) and 14 days (group VII). After the decapitation of the animals during thiopental anaesthesia, a blood samples were taken. It has been found that the introduction of bichromate of potassium in the blood of rats in groups III and IV shows an increase in the content of oxidative stress. Preliminary intragastric administration of ethylthiosulfanylate partially reduced the level of growth of hydroperoxides of lipids and thiobarbituric acid TBA­active products caused by the action of Cr(VI) in groups VI and VII and did not affect the level of carbonyl groups of proteins products, in particular lipid hydroperoxides, thiobarbituric acid (TBA­active products and carbonyl groups of proteins. The work of the glutathione link of an tioxidant protection under the influence of Cr(VI) was partially activated in group III, but suppressed in group IV. Ethylthiosulfanylate separately (group V) and in combination with Cr(VI) (groups VІ and VІІ) caused activation of glutathione reductase and increased GSN concentration in erythrocytes of rats compared with group ІІ. Superoxide dismutase and catalase activity of rat erythrocytes were increased by the action of Cr(VI) in groups III and IV in comparison with group I. However, with the effect of ethylthiosulfanylate in Cr(VI) complex, superoxide dismutase activity was increased in VII and catalase activity in VI and VII groups decreased, compared to group II.","PeriodicalId":22372,"journal":{"name":"The Animal Biology","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86154064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of tetracycline injection on blood calcium and ruminal activity in sheep","authors":"P. Mudroň","doi":"10.15407/animbiol21.04.071","DOIUrl":"https://doi.org/10.15407/animbiol21.04.071","url":null,"abstract":"Tetracycline is widely used in the treatment of the foot rot in ruminants. It chelates with Ca 2+ ions causing a depression of levels of ionised calcium. The objective of the study was to assess effects of tetracycline admin istration on serum calcium concentrations and the frequency of ruminal contractions. Rumen contractions were monitored by auscultation in 23 sheep prior to administration of oxytetracycline and recorded every 12 hours for 84 hours after intramuscular injection of the antibiotic. Blood for calcium analyses was collected by venepunc-ture of the jugular vein before and 24, 48, 72, and 96 hours after administration of oxytetracycline. The serum calcium concentrations were determined by atomic absorption spectrophotometry. Analysis of variance (ANOVA) was used to analyse the time effect of tetracycline treatment on the rumen contractions and serum calcium con -centrations. There was a significant decrease (P<0.01) in ruminal contractions following application of oxytetracycline, with a maximum decrease at 24 hours following oxytetracycline application and a return to the initial rumen contraction frequency by 60–72 hours following oxytetracycline application. The oxytetracycline administration resulted in serum calcium decrease from 2.42 mmol/l to 2.26 mmol/l 24 hours after the administration (P<0.01). In conclusion, as found in our study the administration of tetracycline in sheep can be associated with a decline in ruminal motility potentially causing production losses, particularly in lactating ewes.","PeriodicalId":22372,"journal":{"name":"The Animal Biology","volume":"99 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74825846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Some indexes of carbohydrate metabolism in mice under action of modified pectin","authors":"A. Vovkohon, Bila Tserkva Ukraine Soborna sq.","doi":"10.15407/animbiol21.04.018","DOIUrl":"https://doi.org/10.15407/animbiol21.04.018","url":null,"abstract":"., The search for new and improvement of approved carriers for biotechnological methods and processes of immobilized enzymes and microorganisms’ cells is quite actual. The mostly applied are those carriers which are widely available and not expensive. Also, the carriers used in the food industry should be non-toxic and me-tabolized or quickly excreted from the organism. The physical and chemical properties of pectin as a food additive allow using it as natural carrier. However, to increase the sorption properties of pectin, at the Research Institute of food technologies and technologies of animal products processing of Bila Tserkva national agrarian university a technology of its modification has been developed. The harmlessness indexes of pectin were studied on white mice. After the experiment on the harmlessness ended, some carbohydrate metabolism indexes were defined for the mice body under the action of different doses of modified pectin. Three groups of experimental animals with body weight 19–20 g were created containing 5 animals in each group. The studies on the content of glucose, pyruvic and lactic acids were conducted in the blood serum. The glycogen content was studied in the liver of linear mice. The feeding, maintenance and keeping of mice during experiment were carried out according to the modern bioethics require-ments. It has been found out that at the end of experiment (the day 11 after the intragastric infusion of 0.3 cm 3 5.0 % modified pectin suspension), there were no changes as to the glucose, pyruvic and lactic acids in the blood serum and glycogen in liver compared to the animals infused by the physiological solution. The was no probable increase of glucose, pyruvic and lactic acids in the blood serum and glycogen in the liver of mice infused by 0.3 cm 3 10.0 % of modified pectin suspension compared to the animals of control group. Thus, there was identified no violation of carbohydrate metabolism in the mice bodies after one-time infusion of 0.3 cm 3 5.0 % and 10.0 % modified pectin suspension, indicating that there is no toxic effect of the test substance on the body of white mice.","PeriodicalId":22372,"journal":{"name":"The Animal Biology","volume":"86 1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86488789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between alleles of gene BoLA-DRB3 and somatic cells amount in milk of Ukrainian black-and-white dairy breed","authors":"T. Suprovych, O. Vishchur, M. Suprovych, V. Chepurna","doi":"10.15407/animbiol21.04.075","DOIUrl":"https://doi.org/10.15407/animbiol21.04.075","url":null,"abstract":"A significant genetic correlation between the indicator of the somatic milk cells amount (SCC) and intrama mmary infection has been established, making it possible to use it in breeding programs for reducing of mastitis in cows. Various studies demonstrated that resistance (susceptibility) to mastitis is genetically predetermined. Among the genes associated with diseases, special attention is paid to exon 2 of the gene BoLA-DRB3, which is quite polymor -phic. The aim of the study was to identify associations between alleles of the gene BoLA-DRB3 and SCC among cows of Ukrainian black-and-white dairy breed (N = 92). The RFLP-PCR method revealed 31 BoLA-DRB3.2 alleles. The relative risk index and the χ 2 test were used to establish a link between the allele frequencies and the SCC. Two alleles with strong association with low level of SCC (CI = 0.95): BoLA-DRB3.2*22 (P(A) = 0 . 06; RR = – 3 . 43; χ 2 = 3 . 84) and BoLA-DRB3.2*28 (P(A) = 0 . 076; RR = -4 . 14; χ 2 = 6 . 17)were revealed,. An additional check using the precise Fisher’s exact test controlled by Pearson’s contingency coefficient showed that only allele BoLA-DRB 3.2*28 can be used as a marker in connection with low SCC in cows of Ukrainian black-and-white dairy breed. The allele *28 as a SCC marker was revealed for the first time. Analysis of previous studies shows discrepancies between the results that link different BoLA-DRB3.2 alleles with SCC, obtained for different breeds and even within the same breed. In future, it is necessary to expand the research by increasing the research sample and determine the associations between the number of somatic cells not only in connection with allelic polymorphism, but also in connection with the genotypes of the BoLA-DRB3 gene. Interstitial application of the new antibacterial liposomal preparation has led to a decrease in the number of somatic cell cultures in the afflicted animals with subclinical mastitis of cows.","PeriodicalId":22372,"journal":{"name":"The Animal Biology","volume":"20 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82368945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of silicon compounds on the mineral elements content in tissues of rabbits’ organism","authors":"A. I. Ivanitskaya, Y. Lesyk, H. Denys","doi":"10.15407/animbiol21.04.031","DOIUrl":"https://doi.org/10.15407/animbiol21.04.031","url":null,"abstract":"The article presents the effect of drinking rabbits from 52 to 110 days of life silicon citrate obtained by the method using nanotechnology at the rate of 25; 50 and 75 µg Si/kg body weight and sodium metasilicate in the amount of 2.5 and 5.0 mg Si/kg body weight on the mineral elements content in the tissues of the organism. Significant differences between Calcium, Cobalt, Zinc, Ferum, Cuprum, and Manganese content in liver, muscle, tubular bone, skin, wool, and blood of rabbits were determined depending on the amount and compound of silicon in the rabbit diet. Feeding silicon citrate in the smallest (25 μg Si) of the studied quantity was indicated by a significant increase ( P <0.05–0.01) of Si in skin and wool tissues, Zn in skin, Ca and Fe in blood and Cu in rabbit liver. The use of silicon citrate at the rate of 50 and 75 μg Si/kg body weight caused unidirectional changes in the studied tissues of rabbits with a likely increase ( P <0.05–0.001) content of Ca, Si, Co, Zn, Fe and Cu in the blood rabbits. This may indicate the synergistic effect of the amount of organic compound applied to silicon, since despite significant fluctuations in the amount of silicon entering the body, its content in the blood remains stable. A significant ( P <0.05–0.01) increase in the content of Ca, Si, Co, Zn, tissue of the longest muscle of the back, Si and Zn in skin, Si in wool, and higher Co level in the tubular bone tissue compared to the control group was found. The content of trace elements in rabbit tissues for the absorption of sodium metasilicate in the amount of 2.5 and 5.0 mg Si/kg body weight retained significantly less influence of the probable differences compared to the control group with more pronounced influence of lower amount, in particu-lar: Ca, Si, Fe in blood, Co in liver, Si in muscle tissues, Ca, Si and Zn in wool and skin. The established changes in the content of macro- and microelements in the tissues of the rabbit organism mark tissue specificity and depend on the compound of silicon used and their amount in the diet. The synergistic effect of the use of silicon compounds was more pronounced than the effect of silicon citrate in the amount of 50 and 75 µg Si/kg body weight, which may indicate a stimulating effect of silicon on the correction of mineral metabolism in their body.","PeriodicalId":22372,"journal":{"name":"The Animal Biology","volume":"439 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76329599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Haptoglobin concentrations in blood of dairy cows with inflammatory diseases","authors":"P. Mudroň","doi":"10.15407/animbiol21.03.061","DOIUrl":"https://doi.org/10.15407/animbiol21.03.061","url":null,"abstract":"Haptoglobin is an acute phase protein produced primarily in the liver in response to pro-inflammatory cytokines. The objective of this field study was to determine if common inflammatory diseases like mastitis and claw inflammatory disorders are associated with increased serum haptoglobin. Moreover, the sensitivity and specificity of haptoglobin levels were tested. 237 Holstein dairy cows were included in the study; farm feeding management was based on TMR and the dairy cows were housed in free stalls with cubicles. Health condition of mammary gland and claws was examined in the crush. The subclinical mastitis was diagnosed by using California mastitis test. Blood samples were obtained from the jugular vein at the time of the clinical examination and treatment. Serum haptoglobin concentration was measured by colorimetric assay (Tridelta Development, Ireland). Statistical analysis was done by two-way ANOVA. The threshold level of haptoglobin for calculation of sensitivity and specificity was 0.05 g/L. Clinical mastitis, subclinical mastitis, and inflammatory claw disorders, including digital dermatitis, inter digital dermatitis, pododermatitis, interdigital hyperplasia, and subclinical laminitis were found in 204 dairy cows (INFLA). 33 dairy cows were found to be free of inflammatory changes (CONTROL). Cows with inflammation had higherserum haptoglobin than controls: INFLA — 0.21 g/L; CONTROL — 0.06 g/L (P<0.01). The sensitivity de tecting dairy cows with inflammatory disorders by serum haptoglobin levels was 84 %, whereas the specificity in the control group of 33 clinically unsuspicious cows was 68 %. Results of the study show that the inflammatory dis orders in dairy cows are associated with increased concentrations of the serum haptoglobin. However, sensitivity and specificity of the serum haptoglobin are rather low for detection of inflammatory processes in dairy cows.","PeriodicalId":22372,"journal":{"name":"The Animal Biology","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81073336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}