{"title":"Preterm labour in association with Neisseria gonorrhoeae: case reports.","authors":"C J Lacey, J D Milne","doi":"10.1136/sti.60.2.123","DOIUrl":"https://doi.org/10.1136/sti.60.2.123","url":null,"abstract":"<p><p>We describe two cases of spontaneous rupture of the membranes, followed by premature labour at 32 and 34 weeks' gestation, in association with gonococcal infection.</p>","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":"60 2","pages":"123-4"},"PeriodicalIF":0.0,"publicationDate":"1984-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/sti.60.2.123","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17758895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sociological and psychological predictors of STD infection in homosexual men: a study of four countries.","authors":"M W Ross","doi":"10.1136/sti.60.2.110","DOIUrl":"https://doi.org/10.1136/sti.60.2.110","url":null,"abstract":"<p><p>I investigated over 600 homosexual men in four countries (Sweden, Finland, Ireland, and Australia) regarding the number of times they had contracted a sexually transmitted disease (STD) and several psychological variables including masculinity and feminity, sex role conservatism, relationships with parents, number of sexual partners, attitudes towards homosexuality, and involvement in the homosexual subculture. Using multiple linear regression in each country, it was found that 19-42% of the variance of number of times infected could be accounted for by psychosocial factors, seven of which were common to all countries. The number of sexual partners was not a significant variable in any country. These data strongly suggest that numbers of infections in homosexual men are best predicted by psychological factors, and this has considerable implications for preventative and treatment programmes for homosexuals.</p>","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":"60 2","pages":"110-3"},"PeriodicalIF":0.0,"publicationDate":"1984-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/sti.60.2.110","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17603771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Parotitis with secondary syphilis: a case report.","authors":"S K Hira, R S Hira","doi":"10.1136/sti.60.2.121","DOIUrl":"https://doi.org/10.1136/sti.60.2.121","url":null,"abstract":"<p><p>Painless swelling of the parotid salivary gland was observed in a patient presenting with secondary syphilis. This case is of special interest to venereologists and surgeons as parotitis associated with syphilis may be mistaken for common tumours of the parotid glands. A diagnosis of syphilitic parotitis should be considered in patients presenting with swollen parotid salivary glands in countries where syphilis is prevalent.</p>","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":"60 2","pages":"121-2"},"PeriodicalIF":0.0,"publicationDate":"1984-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/sti.60.2.121","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17758894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Differentiation of gonococcal and non-gonococcal neisseriae by the superoxol test.","authors":"H Young, A B Harris, J W Tapsall","doi":"10.1136/sti.60.2.87","DOIUrl":"https://doi.org/10.1136/sti.60.2.87","url":null,"abstract":"We evaluated the superoxol (catalase) test as a means of differentiating gonococci from related species of organisms which were cultured from a variety of anatomical sites. An isolate was almost certainly not a gonococcus if it gave a negative superoxol test result, as all but one of 596 available gonococci gave positive test results. However, a proportion of the non-gonococcal neisseriae and isolates of Branhamella catarrhalis, also gave positive test results. The superoxol test is thus a useful addition to the techniques available for the characterisation of gonococci, but additional procedures are needed to confirm the identities of isolates giving positive results.","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":"60 2","pages":"87-9"},"PeriodicalIF":0.0,"publicationDate":"1984-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/sti.60.2.87","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17481890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"T cell proliferative responses to Chlamydia trachomatis antigen in vitro in patients with a history of gynaecological chlamydia infection.","authors":"E Qvigstad, M Onsrud, K Skaug","doi":"10.1136/sti.60.2.132","DOIUrl":"https://doi.org/10.1136/sti.60.2.132","url":null,"abstract":"","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":"60 2","pages":"132"},"PeriodicalIF":0.0,"publicationDate":"1984-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/sti.60.2.132","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17664156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fifth meeting of the International Society for STD Research","authors":"R. Catterall","doi":"10.1136/sti.60.2.129","DOIUrl":"https://doi.org/10.1136/sti.60.2.129","url":null,"abstract":"The fifth meeting of the International Society for STD Research was held at the Seattle Sheraton Hotel on 1-3 August 1983. It was preceded by a clinical update course on Sexually Transmitted Diseases (STDs) held on 31 July 1983 at the same hotel. About 300 participants took part in a lively meeting in which the current state of knowledge of several sexually transmitted diseases and syndromes were reviewed by experts in their particular fields. The standards of the papers and their presentation was very high and many lively discussions had to be curtailed by the chairman because of lack of time. Dr King Holmes of Seattle reviewed the whole field of STDs, and suggested that we might now be seeing the emergence of a third generation of STDs, of which the acquired immune deficiency syndrome (AIDS) was the first and most striking example. He also drew attention to the recent clarification of several STD syndromes such as genital ulcer disease, lower genital tract infection in women, pelvic inflammatory disease, ectopic pregnancy and infertility, fetal and neonatal infections, and genital neoplastic disease and its relation to certain viral infections. The review was very detailed but only included conditions which were increasing in incidence or remaining very prevalent. For example, no mention was made of the virtual disappearance","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":"18 1","pages":"129 - 131"},"PeriodicalIF":0.0,"publicationDate":"1984-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85069841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ceftizoxime in the treatment of uncomplicated gonorrhoea.","authors":"R C Spencer, T Smith, M D Talbot","doi":"10.1136/sti.60.2.90","DOIUrl":"https://doi.org/10.1136/sti.60.2.90","url":null,"abstract":"<p><p>A total of 74 men and 26 women with uncomplicated gonorrhoea were treated with ceftizoxime sodium 0.5 g intramuscularly. The cure rate was 99% and included successful treatment of four infections due to beta-lactamase producing organisms. The minimum inhibitory concentrations (MICs) of ceftizoxime in vitro were very much lower than those of penicillin and cefuroxime, and side effects were minimal. We conclude that ceftizoxime is effective against Neisseria gonorrhoeae in vivo and in vitro.</p>","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":"60 2","pages":"90-1"},"PeriodicalIF":0.0,"publicationDate":"1984-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/sti.60.2.90","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17384309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R A Strugnell, C J Handley, L Drummond, S Faine, D A Lowther, S R Graves
{"title":"Polyanions in syphilis: evidence that glycoproteins and macromolecules resembling glycosaminoglycans are synthesised by host tissues in response to infection with Treponema pallidum.","authors":"R A Strugnell, C J Handley, L Drummond, S Faine, D A Lowther, S R Graves","doi":"10.1136/sti.60.2.75","DOIUrl":"https://doi.org/10.1136/sti.60.2.75","url":null,"abstract":"<p><p>We investigated by means of radiolabelled precursors the source and nature of the polyanionic macromolecules present in rabbit tissues during active syphilis infection. Previous studies indicated that Treponema pallidum itself does not synthesise glycosaminoglycans, at least in vitro. In replicate experiments on unilaterally infected rabbits, tissue from the orchitic testis incorporated two to three times more 35S-sulphate and 3H-glucosamine (on a wet weight basis) than tissue from the non-orchitic contralateral testis. Incorporation of 35S-sulphate was independent of the number of viable T pallidum organisms present in the infested tissue, which suggested that incorporation represented biosynthesis by the host and not the treponeme. Testes from syphilitic rabbits two days after treatment with high doses (100 mg/kg) of penicillin incorporated less 35S-sulphate than untreated infected testes, but more than normal uninfected rabbit testes. This suggests that active syphilitic infection was necessary for maximum biosynthesis of the macromolecule(s) by host tissue. Hydrodynamic profiles showed incorporation of radiolabelled precursors into two distinct fractions of different sizes, which may represent a proteoglycan and a sulphated glycoprotein. Alcian blue staining of syphilitic testes at or after peak orchitis showed focal deposition of newly synthesised polyanionic components during peak orchitis and a more generalised fibrosis in testes after peak orchitis.</p>","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":"60 2","pages":"75-82"},"PeriodicalIF":0.0,"publicationDate":"1984-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/sti.60.2.75","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17758897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"STD in British Columbia.","authors":"R D Catterall","doi":"10.1136/sti.60.2.127","DOIUrl":"https://doi.org/10.1136/sti.60.2.127","url":null,"abstract":"","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":"60 2","pages":"127-8"},"PeriodicalIF":0.0,"publicationDate":"1984-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/sti.60.2.127","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17603772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Treatment of uncomplicated anogenital gonorrhoea with a single oral dose of 3 g amoxycillin combined with 250 mg clavulanic acid.","authors":"A H De Silva, S A Bashi, R Basu Roy","doi":"10.1136/sti.60.2.132-a","DOIUrl":"https://doi.org/10.1136/sti.60.2.132-a","url":null,"abstract":"Sir, The importance of Chlamydia trachomatis in genital tract infections is well established.1-4 The humoral immune responses during chlamydial infections have been examined with several serological techniques,5 and in vitro cellular immune responses to chlamydial antigens in man have been studied with different assays.6-8 We report on the immune response after local and more severe chlamydial infections. One group of patients consisted of 10 women who had had acute salpingitis 1-2 years before, probably caused by C trachomatis. The women had had a positive chlamydial culture from the cervix and a fourfold or more rise in chlamydial IgG antibody titre during the disease. The other group consisted of 10 women who 1-2 months earlier had had chlamydial cervicitis, with only lower genital tract symptoms. T cells and non-T cells were prepared from defibrinated blood, as described previously.8 A suspension of partially purified C trachomatis subtype LGV-2 was used as antigen throughout the study.8 An enzyme","PeriodicalId":22309,"journal":{"name":"The British Journal of Venereal Diseases","volume":"60 2","pages":"132-3"},"PeriodicalIF":0.0,"publicationDate":"1984-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/sti.60.2.132-a","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17758896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}